Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 80, 2016 - Issue 1
Journal homepage
1,013
Views
22
CrossRef citations to date
0
Altmetric
Food & Nutrition Science

Ameliorative effect of betulin from Betula platyphylla bark on scopolamine-induced amnesic mice

Namki ChoMolecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA;College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul, Republic of Korea
,
Hyeon Woo KimCollege of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul, Republic of Korea
,
Hee Kyoung LeeInstitute for Life Science, Elcom Science Co. Ltd., Seoul, South Korea
,
Byung Ju JeonInstitute for Life Science, Elcom Science Co. Ltd., Seoul, South Korea
&
Sang Hyun SungCollege of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul, Republic of KoreaCorrespondence[email protected]
Pages 166-171 | Received 14 May 2015, Accepted 30 Jun 2015, Published online: 19 Aug 2015

Citations (22)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Mahan Farzan, Mahour Farzan, Mehrdad Shahrani, Seyedeh Parisa Navabi, Hossien Rajabi Vardanjani, Hossein Amini-Khoei & Sahreh Shabani. (2023) Neuroprotective properties of Betulin, Betulinic acid, and Ursolic acid as triterpenoids derivatives: a comprehensive review of mechanistic studies. Nutritional Neuroscience 0:0, pages 1-18.
Read now

Articles from other publishers (21)

Xin Ren, Ya Wen, Chang Li, Mu Yuan, Jiejie Zhang, Siyu Li, Xiaowei Zhang, Liang Wang & Shan Wang. (2024) Integrated network pharmacology and comprehensive bioinformatics identifying the mechanisms and molecular targets of Jieyu Anshen Granules for treating comorbidity with Alzheimer's disease and depression. Arabian Journal of Chemistry 17:2, pages 105485.
Crossref
Ting Ou-Yang, Yi Zhang, Heng-Zhen Luo, Yue Liu & Shuang-Cheng Ma. (2023) Novel compounds discovery approach based on UPLC-QTOF-MS/MS chemical profile reveals birch bark extract anti-inflammatory, -oxidative, and -proliferative effects. Journal of Ethnopharmacology 306, pages 116148.
Crossref
Da‐Hye Wang, Eun‐Hie Koh, Kyung Ae Lee & Ha Sook Chung. (2022) Chemical constituents from Betula schmidtii and their free radical scavenging, tyrosinase inhibitory, and neuroprotective activities . Bulletin of the Korean Chemical Society 44:3, pages 256-264.
Crossref
Ting Ouyang, Huafeng Yin, Jianbo Yang, Yue Liu & Shuangcheng Ma. (2022) Tissue regeneration effect of betulin via inhibition of ROS/MAPKs/NF-ĸB axis using zebrafish model. Biomedicine & Pharmacotherapy 153, pages 113420.
Crossref
Peng-Hua Shu, Hui Zhang, Nian-Ci Li, Jia-Long Zhang, Guang-Wei Liu, Yuan Yang, Shuo Zang, Shu-Jing Cai, Xia-Lan Wei, Na Sun & Fu-Gang Xiao. (2022) Natural tyrosinase inhibitors from Betula platyphylla barks . Holzforschung 76:7, pages 674-678.
Crossref
Chenyin Wang & Chaogu Zheng. (2022) Using Caenorhabditis elegans to Model Therapeutic Interventions of Neurodegenerative Diseases Targeting Microbe-Host Interactions. Frontiers in Pharmacology 13.
Crossref
Samantha Hughes, Maritza van Dop, Nikki Kolsters, David van de Klashorst, Anastasia Pogosova & Anouk M. Rijs. (2022) Using a Caenorhabditis elegans Parkinson’s Disease Model to Assess Disease Progression and Therapy Efficiency. Pharmaceuticals 15:5, pages 512.
Crossref
Qiu-yue Xiao, Tian-yuan Ye, Xiao-long Wang, Lu Han, Tong-xing Wang, Dong-mei Qi, Xiao-rui Cheng & Sheng-qi Wang. (2021) A network pharmacology-based study on key pharmacological pathways and targets of Qi Fu Yin acting on Alzheimer's disease. Experimental Gerontology 149, pages 111336.
Crossref
P. Ambili Unni, Girinath G. Pillai & S. Sajithalulu. (2021) Biological processes and key druggable targets involved in age-associated memory loss: A systematic review. Life Sciences 270, pages 119079.
Crossref
Swapnil Pandey, Suresh Chandra Phulara, Shashank Kumar Mishra, Rajesh Bajpai, Anil Kumar, Abhishek Niranjan, Alok Lehri, Dalip Kumar Upreti & Puneet Singh Chauhan. (2020) Betula utilis extract prolongs life expectancy, protects against amyloid-β toxicity and reduces Alpha Synuclien in Caenorhabditis elegans via DAF-16 and SKN-1. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 228, pages 108647.
Crossref
Shayan Amiri, Sanaz Dastghaib, Mazaher Ahmadi, Parvaneh Mehrbod, Forough Khadem, Hamid Behrouj, Mohamad-Reza Aghanoori, Filip Machaj, Mahdi Ghamsari, Jakub Rosik, Andrzej Hudecki, Abbas Afkhami, Mohammad Hashemi, Marek J. Los, Pooneh Mokarram, Tayyebeh Madrakian & Saeid Ghavami. (2020) Betulin and its derivatives as novel compounds with different pharmacological effects. Biotechnology Advances 38, pages 107409.
Crossref
Yo-Han Han, Jeong-Geon Mun, Hee Dong Jeon, Ji-Ye Kee & Seung-Heon Hong. (2019) Betulin Inhibits Lung Metastasis by Inducing Cell Cycle Arrest, Autophagy, and Apoptosis of Metastatic Colorectal Cancer Cells. Nutrients 12:1, pages 66.
Crossref
Phil Jun Lee, Hye-Jin Park, Hee Min Yoo & Namki Cho. (2019) Betulin Protects HT-22 Hippocampal Cells against ER Stress through Induction of Heme Oxygenase-1 and Inhibition of ROS Production. Natural Product Communications 14:12, pages 1934578X1989668.
Crossref
N. G. Komissarova, S. N. Dubovitskii, A. V. Orlov & O. V. Shitikova. (2019) New Conjugates of Betulin with 2-Aminoethanesulfonic Acid. Chemistry of Natural Compounds 55:2, pages 300-304.
Crossref
Madhu Kaundal, Saima Zameer, Abul Kalam Najmi, Suhel Parvez & Mohd Akhtar. (2018) Betulinic acid, a natural PDE inhibitor restores hippocampal cAMP/cGMP and BDNF, improve cerebral blood flow and recover memory deficits in permanent BCCAO induced vascular dementia in rats. European Journal of Pharmacology 832, pages 56-66.
Crossref
Madhu Kaundal, Rahul Deshmukh & Mohd Akhtar. (2018) Protective effect of betulinic acid against intracerebroventricular streptozotocin induced cognitive impairment and neuronal damage in rats: Possible neurotransmitters and neuroinflammatory mechanism. Pharmacological Reports 70:3, pages 540-548.
Crossref
Miloš Lukáč, Branislav Horváth, Martin Pisárčik, Ferdinand Devínsky & Renáta Horáková. (2018) Improved isolation of betulin and lupeol from birch bark and oxidation of their acetylated derivatives with chromyl chloride. Monatshefte für Chemie - Chemical Monthly 149:5, pages 947-952.
Crossref
Kengo Shigetomi, Naoki Okada, Takashi Kumaki, Shinya Mitsuhashi & Makoto Ubukata. (2018) Inhibitory activities of tree bark extracts against AGEs formation and their correlation with phenolic components. Wood Science and Technology 52:3, pages 873-886.
Crossref
Eun-Ju YangJu-Hee AnYoun Kyoung SonJoo-Hong YeoKyung-Sik Song. (2018) The Cytotoxic Constituents of Betula platyphylla and their Effects on Human Lung A549 Cancer Cells . Natural Product Sciences 24:4, pages 219.
Crossref
Chia-Wen Tsai, Rong-Tzong Tsai, Shih-Ping Liu, Chang-Shi Chen, Min-Chen Tsai, Shao-Hsuan Chien, Huey-Shan Hung, Shinn-Zong Lin, Woei-Cherng Shyu & Ru-Huei Fu. (2018) Neuroprotective Effects of Betulin in Pharmacological and Transgenic Caenorhabditis elegans Models of Parkinson’s Disease . Cell Transplantation 26:12, pages 1903-1918.
Crossref
Kathyani Parasram. (2017) Flavonoids and Diarylheptanoids: Neuroprotective Activities of Phytochemicals. International Journal of Pharmacology, Phytochemistry and Ethnomedicine 6, pages 82-86.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.