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Bioscience, Biotechnology, and Biochemistry Volume 82, 2018 - Issue 8
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Organic Chemistry

A curcumin-diglutaric acid conjugated prodrug with improved water solubility and antinociceptive properties compared to curcumin

Chawanphat MuangnoiNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
,
Ponsiree JithavechNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
,
Pahweenvaj Ratnatilaka Na BhuketNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
,
Wiwat SupasenaNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
,
Wisut WichitnithadNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
,
Pasarapa TowiwatNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
,
Nuansri NiwattisaiwongDepartment of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand;School of Pharmacy, Eastern Asia University, Pathumthani, Thailand
,
Ian S. HaworthDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA
&
Pornchai RojsitthisakNatural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, Thailand;Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, ThailandCorrespondence[email protected]
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Pages 1301-1308 | Received 20 Dec 2017, Accepted 01 Apr 2018, Published online: 20 Apr 2018

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Ying Peng, Mingyue Ao, Baohua Dong, Yunxiu Jiang, Lingying Yu, Zhimin Chen, Changjiang Hu & Runchun Xu. (2021) Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures. Drug Design, Development and Therapy 15, pages 4503-4525.
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Hamid Rashidzadeh, Seyed Jamal Tabatabaei Rezaei, Sahar Zamani, Elnaz Sarijloo & Ali Ramazani. (2021) pH-sensitive curcumin conjugated micelles for tumor triggered drug delivery. Journal of Biomaterials Science, Polymer Edition 32:3, pages 320-336.
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