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Original Articles

Tocilizumab for the Treatment of Behçet Uveitis that Failed Interferon Alpha and Anti-Tumor Necrosis Factor-Alpha Therapy

, MD, , MD & , MD
Pages 1005-1014 | Received 16 Apr 2017, Accepted 11 Jul 2017, Published online: 11 Oct 2017

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Read on this site (7)

Alice Bitossi, Irene Mattioli, Alessandra Bettiol, Adalgisa Palermo, Danilo Malandrino, Daniela Bacherini, Gianni Virgili, Fabrizio Giansanti, Lorenzo Vannozzi & Elena Silvestri. (2023) Non-anti TNFα biologic agents for noninfectious uveitis associated with systemic inflammatory diseases: a systematic review. Expert Review of Clinical Immunology 19:5, pages 549-560.
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Antonio Vitale, Valeria Caggiano, Virginia Berlengiero, Maria Orsetta Perfetti, Jurgen Sota, Gian Marco Tosi, Bruno Frediani, Luca Cantarini & Claudia Fabiani. (2023) Comparing biologic options for the management of Behcet’s disease-related uveitis. Expert Review of Clinical Immunology 19:3, pages 315-328.
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Gunay Uludag, Irmak Karaca, Amir Akhavanrezayat, Cigdem Yasar, Wataru Matsumiya, Brandon Huy Pham, Muhammad Sohail Halim, Ngoc Trong Tuong than, Yasir J. Sepah, Diana V. Do & Quan Dong Nguyen. (2022) Efficacy and Safety of Tocilizumab in the Management of Non-Infectious Uveitis Failed with Conventional Immunomodulatory and Anti-TNFα Therapies. Ocular Immunology and Inflammation 0:0, pages 1-7.
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Ilknur Tugal-Tutkun & Pinar Çakar Özdal. (2020) Behçet’s disease uveitis: is there a need for new emerging drugs?. Expert Opinion on Emerging Drugs 25:4, pages 531-547.
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Mitsuhiro Akiyama, Yuko Kaneko & Tsutomu Takeuchi. (2020) Does microbiome contribute to HLA-B52-positive Takayasu arteritis?. Modern Rheumatology 30:1, pages 213-217.
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Emmett T. Cunningham & Manfred Zierhut. (2018) Uveitic Macular Edema. Ocular Immunology and Inflammation 26:7, pages 987-990.
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Mohammad Avarand, Mine Esen Baris, Leila Taheri & Suzan Guven Yılmaz. Efficacy of Pegylated Interferon Alpha-2a in Uveitic Macular Edema Refractory to Biologic Agents. Ocular Immunology and Inflammation 0:0, pages 1-6.
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Articles from other publishers (34)

Ina Kötter. (2023) Behçet- und Cogan-Syndrom. Laryngo-Rhino-Otologie.
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Dan Hu & Jian-Long Guan. (2023) The roles of immune cells in Behçet’s disease. Advances in Rheumatology 63:1.
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Irmak Karaca, Gunay Uludag, Wataru Matsumiya, Jonathan Regenold, Christopher Or, Azadeh Mobasserian, Muhammad Sohail Halim, Moosa Zaidi, Sherin Lajevardi, Ami Dongchau, Hashem Ghoraba & Quan Dong Nguyen. (2022) Six-month outcomes of infliximab and tocilizumab therapy in non-infectious retinal vasculitis. Eye 37:11, pages 2197-2203.
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Gülen Hatemi, Didar Uçar, Uğur Uygunoğlu, Hasan Yazici & Yusuf Yazici. (2023) Behçet Syndrome. Rheumatic Disease Clinics of North America 49:3, pages 585-602.
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Ruihan Xiao, Chunyan Lei, Yi Zhang & Meixia Zhang. (2023) Interleukin-6 in retinal diseases: From pathogenesis to therapy. Experimental Eye Research 233, pages 109556.
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Mohamed-Yacine Khitri, Alessandra Bartoli, Georgina Maalouf, Alban Deroux, Carlo Salvarani, Giacomo Emmi, Omer Karadag, Gerard Espinosa, Mathilde Leclercq, Gabriele Simonini, Mathieu Vautier, Patrice Cacoub & David Saadoun. (2023) Tocilizumab in Behçet Disease: A Multicenter Study of 30 Patients. The Journal of Rheumatology 50:7, pages 916-923.
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M. Joubert, A.-C. Desbois, F. Domont, A. Ghembaza, A. Lejoncour, A. Mirouse, G. Maalouf, M. Leclercq, S. Touhami, P. Cacoub, B. Bodaghi & D. Saadoun. (2023) Behçet's disease uveitis. La Revue de Médecine Interne.
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Morgane Joubert, Anne-Claire Desbois, Fanny Domont, Amine Ghembaza, Alexandre Le Joncour, Adrien Mirouse, Georgina Maalouf, Mathilde Leclercq, Sarah Touhami, Patrice Cacoub, Bahram Bodaghi & David Saadoun. (2023) Behçet’s Disease Uveitis. Journal of Clinical Medicine 12:11, pages 3648.
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Janine Yunfan Yang, David Goldberg & Lucia Sobrin. (2023) Interleukin-6 and Macular Edema: A Review of Outcomes with Inhibition. International Journal of Molecular Sciences 24:5, pages 4676.
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Ina Kötter. (2022) Behçet- und Cogan-Syndrom. Aktuelle Rheumatologie 48:01, pages 43-49.
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Xue Wu, Mengying Tao, Ling Zhu, Ting Zhang & Ming Zhang. (2022) Pathogenesis and current therapies for non-infectious uveitis. Clinical and Experimental Medicine 23:4, pages 1089-1106.
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Shereen H. Aboul Naga, Lameece Moustafa Hassan, Radwa T. El Zanaty, Mohammad Refaat, Rana H. Amin, Gaafar Ragab & Mahmoud M. Soliman. (2022) Behçet uveitis: Current practice and future perspectives. Frontiers in Medicine 9.
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Hua Zhong, Tian Liu, Yanying Liu, Xiaoying Zhang, Yunshan Zhou & Yin Su. (2022) Efficacy and safety of tocilizumab in Behçet’s syndrome with refractory arterial lesions: a single-centre observational cohort study in China. Rheumatology 61:7, pages 2923-2930.
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Ovgu Kul Cinar, Micol Romano, Ferhat Guzel, Paul A. Brogan & Erkan Demirkaya. (2022) Paediatric Behçet’s Disease: A Comprehensive Review with an Emphasis on Monogenic Mimics. Journal of Clinical Medicine 11:5, pages 1278.
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Luca MASTORINO, Gianluca AVALLONE, Paolo DAPAVO, Martina MERLI, Andrea AGOSTINI, Damiano GRANDINETTI, Maria T. FIERRO, Pietro QUAGLINO & Simone RIBERO. (2022) Tocilizumab and its usage for skin diseases. Italian Journal of Dermatology and Venereology 157:1.
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Shukai Zhan, Caiguang Liu, Na Li, Tong Li, Zhenyi Tian, Min Zhao, Dongxuan Wu, Minhu Chen, Zhirong Zeng & Xiaojun Zhuang. (2022) Anti-TNF-α agents for refractory intestinal Behçet’s disease: case series and meta-analysis. Therapeutic Advances in Gastroenterology 15, pages 175628482211166.
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Chun Yan, Fan Li, Min Hou, Xiaoyuan Ye, Lishi Su, Yixin Hu, Jiawen Luo & Wei Chi. (2021) Vascular Abnormalities in Peripapillary and Macular Regions of Behcet's Uveitis Patients Evaluated by Optical Coherence Tomography Angiography. Frontiers in Medicine 8.
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Fatma Alibaz-Oner & Haner Direskeneli. (2021) Advances in the Treatment of Behcet’s Disease. Current Rheumatology Reports 23:6.
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Julie Gueudry, Mathilde Leclercq, David Saadoun & Bahram Bodaghi. (2021) Old and New Challenges in Uveitis Associated with Behçet’s Disease. Journal of Clinical Medicine 10:11, pages 2318.
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Murat Kürtüncü, Burcu Altunrende & Gülşen Akman. 2021. Neuro-Behçet’s Disease. Neuro-Behçet’s Disease 123 149 .
Mathilde Leclercq, Anne-Claire Desbois, Fanny Domont, Georgina Maalouf, Sara Touhami, Patrice Cacoub, Bahram Bodaghi & David Saadoun. (2020) Biotherapies in Uveitis. Journal of Clinical Medicine 9:11, pages 3599.
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Mitsuhiro Akiyama, Yuko Kaneko & Tsutomu Takeuchi. (2020) Effectiveness of tocilizumab in Behcet's disease: A systematic literature review. Seminars in Arthritis and Rheumatism 50:4, pages 797-804.
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Kader Cetin Gedik, Micol Romano, Roberta A. Berard & Erkan Demirkaya. (2020) An Overview of Conventional and Recent Treatment Options for Behcet’s Disease. Current Treatment Options in Rheumatology 6:2, pages 99-127.
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H. Nida Sen. 2020. Whitcup and Nussenblatt's Uveitis. Whitcup and Nussenblatt's Uveitis 326 349 .
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Sinem Nihal Esatoglu & Gulen Hatemi. (2019) Update on the treatment of Behçet’s syndrome. Internal and Emergency Medicine 14:5, pages 661-675.
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Akshay S. Thomas. (2019) Biologics for the treatment of noninfectious uveitis. Current Opinion in Ophthalmology 30:3, pages 138-150.
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A.-C. Desbois, C. Terrada, P. Cacoub, B. Bodaghi & D. Saadoun. (2018) Les manifestations oculaires de la maladie de Behçet. La Revue de Médecine Interne 39:9, pages 738-745.
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Hasan Yazici, Emire Seyahi, Gulen Hatemi & Yusuf Yazici. (2018) Behçet syndrome: a contemporary view. Nature Reviews Rheumatology 14:2, pages 107-119.
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