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Ocular Immunology and Inflammation Volume 27, 2019 - Issue 1
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Long-Term Efficacy and Safety of Interferon Alpha-2a in the Treatment of Chinese Patients with Behçet’s Uveitis Not Responding to Conventional Therapy

Peizeng YangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaCorrespondence[email protected]
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, MD, PhD,
Guo HuangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MM,
Liping DuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Zi YeThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Ke HuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Chaokui WangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Jian QiThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Liang LiangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Lili WuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MD, PhD,
Qingfeng CaoThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing, P. R. ChinaView further author information
, MS &
Aize KijlstraUniversity Eye Clinic Maastricht, Maastricht, The NetherlandsView further author information
, PhD show all
Pages 7-14 | Received 03 May 2017, Accepted 20 Sep 2017, Published online: 17 Oct 2017

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Carla Gaggiano, Jurgen Sota, Stefano Gentileschi, Valeria Caggiano, Salvatore Grosso, Gian Marco Tosi, Bruno Frediani, Luca Cantarini & Claudia Fabiani. (2020) The current status of biological treatment for uveitis. Expert Review of Clinical Immunology 16:8, pages 787-811.
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Articles from other publishers (15)

Zhenyu Zhong, Guannan Su & Peizeng Yang. (2023) Risk factors, clinical features and treatment of Behçet's disease uveitis. Progress in Retinal and Eye Research 97, pages 101216.
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Ezgi Deniz Batu, Seher Sener, Veysel Cam, Nuray Aktay Ayaz & Seza Ozen. (2023) Treatment with Biologic Drugs in Pediatric Behçet’s Disease: A Comprehensive Analysis of the Published Data. BioDrugs 37:6, pages 813-828.
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Desmond Patrick Kidd. (2023) Neurological involvement by Behçet’s syndrome: clinical features, diagnosis, treatment and outcome. Practical Neurology 23:5, pages 386-400.
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Biao Li, Haoran Li, Qun Huang & Yanlin Zheng. (2023) Shaping the Future of Behçet’s Uveitis Management: A Comprehensive Review of Efficacy, Challenges, and Prospects of Biologic Therapies. Ophthalmology and Therapy.
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Kun He, Xiaxiao Yan & Dong Wu. (2023) Intestinal Behcet’s Disease: A Review of the Immune Mechanism and Present and Potential Biological Agents. International Journal of Molecular Sciences 24:9, pages 8176.
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Yunyun Zhu, Qiuyue Yu, Guannan Su, Na Shao, Jie Feng, Xiang Luo, Chunjiang Zhou & Peizeng Yang. (2023) Interferon-α2a induces CD4+ T cell apoptosis and suppresses Th1/Th17 responses via upregulating IRF1-mediated PDL1 expression in dendritic cells from Behcet’s uveitis. Clinical Immunology 250, pages 109303.
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Simple GuptaK. ShyamsundarMohini Agrawal, Nitin VichareJyotirmay Biswas. (2022) Current Knowledge of Biologics in Treatment of Noninfectious Uveitis. Journal of Ocular Pharmacology and Therapeutics 38:3, pages 203-222.
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Luxi Sun, Yunxia Hou, Lifan Zhang, JinJing Liu, Lu Li, Zhimian Wang, Xin Yu, Menghao Zhang, Xiaoqing Liu, Yan Zhao & Wenjie Zheng. (2022) Effectiveness and safety of low-dose interferon alpha-2a treatment in Behçet’s Syndrome with refractory vascular or neurological involvement: a case series. Therapeutic Advances in Chronic Disease 13, pages 204062232211112.
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Fatema T. Elgengehy, Sherif M. Gamal, Nesreen Sobhy, Ibrahem Siam, Ahmed M. Soliman, Ghada W. Elhady & Tamer A. Gheita. (2021) Vasculitis damage index in Behçet’s disease. Advances in Rheumatology 61:1.
Crossref
Yujing Qian, Yi Qu, Fei Gao, Minghang Pei, Anyi Liang, Junyan Xiao, Chan Zhao & Meifen Zhang. (2021) Comparison of the Safety and Efficacy of Interferon Alpha-2a and Cyclosporine-A When Combined With Glucocorticoid in the Treatment of Refractory Behçet’s Uveitis: A Randomized Controlled Prospective Study. Frontiers in Pharmacology 12.
Crossref
Sang-Wan Chung. (2021) Vasculitis: From Target Molecules to Novel Therapeutic Approaches. Biomedicines 9:7, pages 757.
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Zhenyu Zhong, Guannan Su, Aize Kijlstra & Peizeng Yang. (2021) Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis. Progress in Retinal and Eye Research 80, pages 100866.
Crossref
Peizeng YangPeizeng Yang. 2021. Atlas of Uveitis. Atlas of Uveitis 155 161 .
Peizeng YangPeizeng Yang. 2021. Atlas of Uveitis. Atlas of Uveitis 339 410 .
Yılmaz Özyazgan & Ilknur Tugal-Tutkun. 2020. Behçet Syndrome. Behçet Syndrome 51 71 .

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