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Ocular Immunology and Inflammation Volume 28, 2020 - Issue 2
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Original Article

Uveitis in Patients Treated with CTLA-4 and PD-1 Checkpoint Blockade Inhibition

Michel M. Sun M.D., Ph.D.Department of Ophthalmology, Jules Stein Eye Institute, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7983-4985View further author information
ORCID Icon,
Ralph D. Levinson M.D.Department of Ophthalmology, Jules Stein Eye Institute, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USAView further author information
,
Artur Filipowicz D.O.Department of Ophthalmology, Massachusetts Eye Research and Surgical Institution, Waltham, MA, USAView further author information
,
Stephen Anesi M.D.Department of Ophthalmology, Massachusetts Eye Research and Surgical Institution, Waltham, MA, USAView further author information
,
Henry J. Kaplan M.D.Department of Ophthalmology, University of Louisville, Louisville, KY, USAView further author information
,
Wei Wang M.D., Ph.D.Department of Ophthalmology, University of Louisville, Louisville, KY, USAView further author information
,
Debra A. Goldstein M.D.Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USAView further author information
,
Sapna Gangaputra M.D.Department of Ophthalmology, Vanderbilt Eye Institute, Nashville, TN, USAView further author information
,
Robert T. Swan M.D.Department of Ophthalmology, SUNY Upstate Medical University, Syracuse, NY, USAView further author information
,
H. Nida Sen M.D.National Eye Institute, NIH, Bethesda, MD, USAView further author information
&
Lynn K. Gordon M.D., Ph.D.Department of Ophthalmology, Jules Stein Eye Institute, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USAView further author information
 show all
Pages 217-227 | Received 09 Oct 2018, Accepted 30 Jan 2019, Published online: 01 Mar 2019

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Richmond Woodward, Andrew Gross, Grant A. Justin, Glenn J. Jaffe & Dilraj S. Grewal. (2023) Bilateral Panuveitis in an Adolescent with Autoimmune Lymphoproliferative Syndrome Due to CTLA4 Haploinsufficiency. Ocular Immunology and Inflammation 0:0, pages 1-5.
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Yinchen Shen, Yuanyuan Gong & Li Su. (2023) Diagnostic Challenges in PD-1 Inhibitor Induced Panuveitis in a Teenage Girl with Chest Soft Tissue Sarcoma - A Case Report. Ocular Immunology and Inflammation 0:0, pages 1-4.
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Qianqian Fan, Huan Chen, Yang Hu & Bin Zhao. (2023) Evaluation of uveitis events in real-world patients receiving immune checkpoint inhibitors based on the FAERS database. Cutaneous and Ocular Toxicology 42:2, pages 68-73.
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Yan-Li Hou, Di-Ya Wang, Jie-Xuan Hu, Ru-Yue Tian, Wei Wang, Qiang Su, Hongyang Li & Yan-Ling Wang. (2022) Risk of Ophthalmic Adverse Events in Patients Treated with Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-analysis. Ocular Immunology and Inflammation 30:6, pages 1449-1459.
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Andrew M Philip, Stephen D Anesi, C Stephen Foster & Peter Chang. (2022) Ocular Inflammatory Complications of Treatment for Metastatic Melanoma. Ocular Immunology and Inflammation 0:0, pages 1-5.
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Busra Yilmaz Tugan, Berna Ozkan & Ozlem Sonmez. (2021) Recurrent Episodes with Serous Retinal Detachment and Anterior Uveitis in a Patient Using Nivolumab (Anti -PD-1 Antibody) Therapy: A case report and literature review. Seminars in Ophthalmology 36:8, pages 794-799.
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Sarah Touhami, Mathilde Leclercq, Dinu Stanescu-Segall, Valérie Touitou & Bahram Bodaghi. (2021) Differential Diagnosis of Vitritis in Adult Patients. Ocular Immunology and Inflammation 29:4, pages 786-795.
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Caberry W Yu, Matthew Yau, Natalie Mezey, Ishraq Joarder & Jonathan A Micieli. (2020) Neuro-ophthalmic Complications of Immune Checkpoint Inhibitors: A Systematic Review. Eye and Brain 12, pages 139-167.
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Tessnim R. Ahmad, Thuy Doan, John A. Gonzales, Nisha R. Acharya & Edmund Tsui. (2020) Clinical Course of Preexisting Uveitis during Treatment of Lung Cancer with Durvalumab. Ocular Immunology and Inflammation 28:4, pages 566-570.
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Larissa A. Habib, Natalie Wolkow, Suzanne K. Freitag & Michael K. Yoon. (2019) Advances in Immunotherapy and Periocular Malignancy. Seminars in Ophthalmology 34:4, pages 327-333.
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Christian Kim, Samantha Paul & Jose Echegaray. (2023) Update on Immune Checkpoint Inhibitor-Associated Uveitis. Current Ophthalmology Reports 11:3, pages 57-67.
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Yunyun Zhu, Qiuyue Yu, Guannan Su, Na Shao, Jie Feng, Xiang Luo, Chunjiang Zhou & Peizeng Yang. (2023) Interferon-α2a induces CD4+ T cell apoptosis and suppresses Th1/Th17 responses via upregulating IRF1-mediated PDL1 expression in dendritic cells from Behcet’s uveitis. Clinical Immunology 250, pages 109303.
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Safia Hsin, Theodor Stappler, Ann Schalenbourg & Yan Guex-Crosier. (2023) Bilateral Severe Panuveitis Occurring during Cancer Immunotherapy with Dabrafenib and Trametinib Therapy Due to Toxoplasmosis Reactivation. Klinische Monatsblätter für Augenheilkunde 240:04, pages 574-577.
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Linyang Gan, Huan Chen, Xiaowei Liu & Li Zhang. (2023) Ophthalmic immune-related adverse events associated with immune checkpoint inhibitors. Frontiers in Immunology 14.
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Nika Vrabic, Ana Fakin, Polona Jaki Mekjavic, Urska Janzic, Martina Vrankar & Natasa Vidovic Valentincic. (2022) Various clinical presentations of uveitis associated with durvalumab treatment. Radiology and Oncology 56:2, pages 129-137.
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Justus G. Garweg. (2022) Uveitisinduktion durch immunonkologische Therapien, speziell Checkpoint-Inhibitoren. Klinische Monatsblätter für Augenheilkunde 239:04, pages 575-581.
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