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Ocular Immunology and Inflammation Volume 28, 2020 - Issue sup1: COTS supplement
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Invited Review

Tubercular Uveitis: Nuggets from Collaborative Ocular Tuberculosis Study (COTS)-1

Ilaria Testi1 Moorfields Eye Hospital, NHS Foundation Trust, London, UKView further author information
, MD,
Rupesh Agrawal2 National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore;3 School of Material Science and Engineering, Nanyang Technological University, Singapore, Singapore;4 Singapore Eye Research Institute, Singapore, SingaporeORCID Iconhttps://orcid.org/0000-0002-6662-5850View further author information
, MD, FRCS,ORCID Icon,
Sarakshi Mahajan5 Byers Eye Institute, Stanford University, Palo Alto, CA, USAView further author information
, MBBS,
Aniruddha Agarwal6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, IndiaORCID Iconhttps://orcid.org/0000-0003-4985-9855View further author information
, MSORCID Icon,
Dinesh Visva Gunasekeran2 National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore;3 School of Material Science and Engineering, Nanyang Technological University, Singapore, SingaporeView further author information
, MBBS,
Dhananjay Raje7 MDS Bioanalytics, Nagpur, IndiaView further author information
, PhD,
Kanika Aggarwal6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, IndiaView further author information
, MS,
Somasheila I. Murthy8 Tej Kohli Cornea Institute, LV Prasad Eye Institute, Hyderabad, IndiaView further author information
, DNB,
Mark Westcott1 Moorfields Eye Hospital, NHS Foundation Trust, London, UKView further author information
, FRCOphth,
Soon Phaik Chee4 Singapore Eye Research Institute, Singapore, Singapore;9 Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeORCID Iconhttps://orcid.org/0000-0002-6308-5721View further author information
, FRCSEdORCID Icon,
Peter McCluskey10 Department of Clinical Ophthalmology & Eye Health, Central Clinical School, Save Sight Institute, The University of Sydney, Sydney, AustraliaView further author information
, MD,
Su Ling Ho2 National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, SingaporeView further author information
, FRCSGlasg,
Stephen Teoh2 National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, SingaporeView further author information
, FRCSEd,
Luca Cimino11 Ocular Immunology Unit, Azienda USL IRCCS, Reggio Emilia, ItalyORCID Iconhttps://orcid.org/0000-0001-7956-9950View further author information
, MDORCID Icon,
Jyotirmay Biswas12 Department of Ophthalmology, Sankara Nethralaya, Chennai, IndiaView further author information
, MS,
Shishir Narain13 Department of Ophthalmology, Shroff Eye Centre, New Delhi, IndiaView further author information
, MD,
Manisha Agarwal14 Department of Ophthalmology, Dr Shroff’s Charity Eye Hospital Daryaganj, New Delhi, IndiaView further author information
, MS,
Padmamalini Mahendradas15 Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, IndiaView further author information
, DNB,
Moncef Khairallah16 Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, TunisiaView further author information
, MD,
Nicholas Jones17 Department of Ophthalmology, University of Manchester, Manchester, UKView further author information
, FRCSOphth,
Ilknur Tugal-Tutkun18 Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul University, Instanbul, TurkeyORCID Iconhttps://orcid.org/0000-0002-4020-453XView further author information
, MDORCID Icon,
Kalpana Babu19 Prabha Eye Clinic & Research Centre, Vittala International Institute of Ophthalmology, Bangalore, IndiaView further author information
, DNB,
Soumayava Basu20 Department of Ophthalmology, LV Prasad Eye Institute, Bhubaneswar, IndiaView further author information
, MS,
Ester Carreño21 Departamento de Oftalmología, Hospital Universitario Fundacion Jimenez Diaz, Madrid, SpainView further author information
, MD,
Richard Lee22 Department of Ophthalmology, Bristol Eye Hospital, Bristol, UKView further author information
, PhD,
Hassan Al-Dhibi23 Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi ArabiaView further author information
, MD,
Bahram Bodaghi24 DHU SightRestore, Department of Ophthalmology, Sorbonne University, Paris, FranceView further author information
, MD,
Alessandro Invernizzi25 Eye Clinic, Department of Biomedical and Clinical Science “L. Sacco”, Luigi Sacco Hospital, University of Milan, Milan, ItalyORCID Iconhttps://orcid.org/0000-0003-3400-1987View further author information
, MDORCID Icon,
Debra A. Goldstein26 Feinberg School of Medicine, Department of Ophthalmology, Northwestern University, Chicago, IL, USAView further author information
, MD,
Carl P. Herbort27 Centre for Ophthalmic Specialised Care, University of Lausanne, Lausanne, SwitzerlandView further author information
, MD,
Talin Barisani-Asenbauer28 The Centre for Ocular Inflammation and Infection (OCUVAC), Laura Bassi Centre of Expertise Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, AustriaView further author information
, PhD,
Julio J. González-López29 Department of Ophthalmology, Ramón y Cajal University Hospital, Madrid, SpainORCID Iconhttps://orcid.org/0000-0001-7210-7809View further author information
, PhDORCID Icon,
Sofia Androudi30 Department of Ophthalmology, University of Thessaly, Larissa, GreeceORCID Iconhttps://orcid.org/0000-0002-5303-7793View further author information
, MDORCID Icon,
Reema Bansal6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, IndiaView further author information
, MS,
Bruttendu Moharana6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, IndiaView further author information
, MS,
Simona Degli Esposti3 School of Material Science and Engineering, Nanyang Technological University, Singapore, SingaporeView further author information
, MD,
Anastasia Tasiopoulou1 Moorfields Eye Hospital, NHS Foundation Trust, London, UKView further author information
, MD,
Sengal Nadarajah1 Moorfields Eye Hospital, NHS Foundation Trust, London, UKView further author information
, MD,
Mamta Agarwal12 Department of Ophthalmology, Sankara Nethralaya, Chennai, IndiaView further author information
, DNB,
Sharanya Abraham12 Department of Ophthalmology, Sankara Nethralaya, Chennai, IndiaView further author information
, MD,
Ruchi Vala15 Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, IndiaView further author information
, MD,
Ramandeep Singh6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, IndiaView further author information
, MS,
Aman Sharma31 Department of Rheumatology, PGIMER, Chandigarh, IndiaORCID Iconhttps://orcid.org/0000-0003-0813-1243View further author information
, MDORCID Icon,
Kusum Sharma32 Department of Microbiology, PGIMER, Chandigarh, IndiaView further author information
, PhD,
Manfred Zierhut33 Centre of Ophthalmology, Department of Ophthalmology, University of Tuebingen, Tuebingen, GermanyView further author information
, PhD,
Andres Rousselot34 Department of Ophthalmology, Universidad del Salvador of Buenos Aires, Buenos Aires, ArgentinaView further author information
, MD,
Robert Grant35 Faculty of Health, Social Care and Education, Kingston University and St George’s, University of London, London, UKView further author information
, MD,
Onn Min Kon36 Chest and Allergy Clinic, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UKView further author information
, MRCP,
Emmett T. Cunningham37 The Francis I. Proctor Foundation, UCSF School of Medicine, San Francisco, California, USAView further author information
, PhD,
John Kempen38 Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA;39 MCM Eye Unit, MyungSung Christian Medical Center and MyungSung Medical School, Addis Ababa, EthiopiaView further author information
, PhD,
Quan Dong Nguyen5 Byers Eye Institute, Stanford University, Palo Alto, CA, USAView further author information
, PhD,
Carlos Pavesio1 Moorfields Eye Hospital, NHS Foundation Trust, London, UKView further author information
, FRCSOpth &
Vishali Gupta6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, IndiaCorrespondence[email protected]
View further author information
, MS show all
Pages 8-16 | Received 23 Feb 2019, Accepted 16 Jul 2019, Published online: 25 Nov 2019

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Yuslay Fernández-Zamora, Luciana Peixoto Finamor, Luci Meire P Silva, Denise S. Rodrigues, Ricardo P. Casaroli-Marano & Cristina Muccioli. (2023) Role of Interferon-Gamma Release Assay for the Diagnosis and Clinical Follow up in Ocular Tuberculosis. Ocular Immunology and Inflammation 31:2, pages 304-311.
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Aniruddha Agarwal & Alessandro Invernizzi. (2022) The Role of Optical Coherence Tomography and Optical Coherence Tomography Angiography in the Differential Diagnosis of Posterior Uveitis. Ocular Immunology and Inflammation 30:3, pages 682-689.
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Jordan L Mitchell, Laura Ganis, Benjamin T. Blacklock, Harry Petrushkin, Jayne C. Hope & Danièlle A. Gunn-Moore. (2022) Ocular Tuberculosis: More than ‘Of Mice and Men’. Ocular Immunology and Inflammation 30:1, pages 34-38.
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Emmett T Cunningham$suffix/text()$suffix/text() & Manfred Zierhut. (2020) HIV/AIDS and the Eye. Ocular Immunology and Inflammation 28:7, pages 1005-1006.
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Ilaria Testi, Rupesh Agrawal, Sarakshi Mahajan, Aniruddha Agarwal, Dinesh Visva Gunasekeran, Dhananjay Raje, Kanika Aggarwal, Somasheila I. Murthy, Mark Westcott, Soon-Phaik Chee, Peter Mccluskey, Su Ling Ho, Stephen Teoh, Luca Cimino, Jyotirmay Biswas, Shishir Narain, Manisha Agarwal, Padmamalini Mahendradas, Moncef Khairallah, Nicholas Jones, Ilknur Tugal-Tutkun, Kalpana Babu, Soumayava Basu, Ester Carreño, Richard Lee, Hassan Al-Dhibi, Bahram Bodaghi, Alessandro Invernizzi, Debra A. Goldstein, Carl P. Herbort, Talin Barisani-Asenbauer, Julio J González-López, Sofia Androudi, Reema Bansal, Bruttendu Moharana, Simona Degli Esposti, Anastasia Tasiopoulou, Sengal Nadarajah, Mamta Agarwal, Sharanaya Abraham, Ruchi Vala, Ramandeep Singh, Aman Sharma, Kusum Sharma, Manfred Zierhut, Onn Min Kon, Emmett T. Cunningham, John H. Kempen, Quan Dong Nguyen, Carlos Pavesio & Vishali Gupta. (2020) The Collaborative Ocular Tuberculosis Study (COTS)-1: A Multinational Descriptive Review of Tubercular Uveitis in Paediatric Population. Ocular Immunology and Inflammation 28:sup1, pages 58-64.
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Aniruddha Agarwal, Rupesh Agrawal, Dhananjay Raje, Ilaria Testi, Sarakshi Mahajan, Dinesh Visva Gunasekeran, Kanika Aggarwal, Somasheila I. Murthy, Mark Westcott, Soon-Phaik Chee, Peter Mccluskey, Su Ling Ho, Stephen Teoh, Luca Cimino, Jyotirmay Biswas, Shishir Narain, Manisha Agarwal, Padmamalini Mahendradas, Moncef Khairallah, Nicholas Jones, Ilknur Tugal-Tutkun, Kalpana Babu, Soumayava Basu, Ester Carreño, Richard Lee, Hassan Al-Dhibi, Bahram Bodaghi, Alessandro Invernizzi, Debra A. Goldstein, Carl P. Herbort, Talin Barisani-Asenbauer, Julio J. González-López, Sofia Androudi, Reema Bansal, Bruttendu Moharana, Simona Degli Esposti, Anastasia Tasiopoulou, Sengal Nadarajah, Mamta Agarwal, Sharanya Abraham, Ruchi Vala, Ramandeep Singh, Aman Sharma, Kusum Sharma, Manfred Zierhut, Onn Min Kon, Emmett T. Cunningham, John H. Kempen, Quan Dong Nguyen, Carlos Pavesio & Vishali Gupta. (2020) Twenty-four Month Outcomes in the Collaborative Ocular Tuberculosis Study (COTS)-1: Defining the “Cure” in Ocular Tuberculosis. Ocular Immunology and Inflammation 28:sup1, pages 65-73.
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Dinesh Visva Gunasekeran, Rupesh Agrawal, Ilaria Testi, Aniruddha Agarwal, Sarakshi Mahajan, Quan Dong Nguyen, Carlos Pavesio & Vishali Gupta. (2020) Lessons in Digital Epidemiology from COTS-1: Coordinating Multicentre Research across 10 Countries Using Operational and Technology Innovation to Overcome Funding Deficiencies. Ocular Immunology and Inflammation 28:sup1, pages 1-7.
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Anamika Patel, Anup Kelgaonkar, Hrishikesh KazaMudit TyagiSomasheila MurthyAvinash Pathengay & Soumyava Basu. (2021) Recent Advances in Diagnosis and Treatment of Infectious Uveitis Prevalent in Asia-Pacific Region. Asia-Pacific Journal of Ophthalmology 10:1, pages 99-108.
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