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Ocular Immunology and Inflammation Volume 30, 2022 - Issue 1
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Research Article

Is Keratoconus an Inflammatory Disease? The Implication of Inflammatory Pathways

I-Ping LohDepartment of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New ZealandCorrespondence[email protected]
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, MSc &
Trevor SherwinDepartment of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New ZealandView further author information
, PhD
Pages 246-255 | Received 30 Jan 2020, Accepted 05 Jun 2020, Published online: 13 Aug 2020

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Tim Berger, Nóra Szentmáry, Ning Chai, Elias Flockerzi, Loay Daas, Tanja Stachon & Berthold Seitz. (2023) In Vitro Expression Analysis of Cytokines and ROS-Related Genes in Human Corneal Fibroblasts and Keratocytes of Healthy and Keratoconus Corneas. Ocular Immunology and Inflammation 0:0, pages 1-10.
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Nazan Acar Eser, Ozlem Dikmetas, Sibel Kocabeyoglu, Cagman Tan & Murat Irkec. (2023) Evaluation of Keratoconus Disease with Tear Cytokine and Chemokine Levels Before and After Corneal Cross-Linking Treatment. Ocular Immunology and Inflammation 0:0, pages 1-7.
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Charles W McMonnies. (2022) Mechanisms of corneal trauma in response to rubbing and other intraocular pressure elevating activities in keratoconus. Expert Review of Ophthalmology 17:6, pages 405-414.
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Articles from other publishers (13)

Rohit Shetty, Krithikaa Mahendran, Parth D. Joshi, Nallathambi Jeyabalan, Chaitra Jayadev & Debashish Das. (2023) Corneal stromal regeneration—keratoconus cell therapy: a review. Graefe's Archive for Clinical and Experimental Ophthalmology.
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Francesco Aiello, Gabriele Gallo Afflitto, Francesca Ceccarelli, Flavia Garzione, Giulio Pocobelli, Carolina Pinci, Giorgio Di Lorenzo, Alberto Siracusano & Carlo Nucci. (2023) Keratoconus and Personality Traits: A Case–Control Study. Cornea Publish Ahead of Print.
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L.E. Cano-Gómez, E. Casillas-Casillas, P. Andrade-Lozano, J. Ventura-Juárez & L.F. Barba-Gallardo. (2023) Modelo animal de ectasia corneal en conejo mediante inyección intraestromal de colagenasa tipo ii. Archivos de la Sociedad Española de Oftalmología 98:4, pages 206-212.
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Pheagane M.W. Nkoana, Vanessa R. Moodley & Khathutshelo P. Mashige. (2023) Keratoconic patient profile and management at public sector facilities in South Africa. African Vision and Eye Health 82:1.
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Mohammad Shirvani, Farhad Soufi, Alireza Nouralishahi, Kimia Vakili, Amirhosseinn Salimi, Brandon Lucke-Wold, Farideh Mousavi, Saman Mohammadzadehsaliani & Shokoufeh Khanzadeh. (2022) The Diagnostic Value of Neutrophil to Lymphocyte Ratio as an Effective Biomarker for Eye Disorders: A Meta-Analysis. BioMed Research International 2022, pages 1-15.
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Mahesh R. Joshi, Kenrick J. Voison, Marianne Piano, Niall Farnon & Peter J. Bex. (2022) A novel tool for quantitative measurement of distortion in keratoconus. Eye.
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Xiao-Dan Hao, Hua Gao, Wen-Hua Xu, Chan Shan, Ying Liu, Zhi-Xia Zhou, Kun Wang & Pei-Feng Li. (2022) Systematically Displaying the Pathogenesis of Keratoconus via Multi-Level Related Gene Enrichment-Based Review. Frontiers in Medicine 8.
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Qian Wang, Yuqing Deng, Saiqun Li, Xinyue Du, Xuan Zhao, Tingting Zhang & Jin Yuan. (2021) Corneal biomechanical changes in allergic conjunctivitis. Eye and Vision 8:1.
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Leanne M. Little & J. Bradley Randleman. (2021) Cogan syndrome masquerading as corneal ectasia. American Journal of Ophthalmology Case Reports 24, pages 101215.
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Sharon D’Souza, Archana Padmanabhan Nair, Ganesh Ram Sahu, Tanuja Vaidya, Rohit Shetty, Pooja Khamar, Ritika Mullick, Sneha Gupta, Mor M. Dickman, Rudy M. M. A. Nuijts, Rajiv R. Mohan, Arkasubhra Ghosh & Swaminathan Sethu. (2021) Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile. Scientific Reports 11:1.
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Prince Kwaku Akowuah, Emmanuel Kobia‐Acquah, Richard Donkor, Joseph Adjei‐Anang & Stephen Ankamah‐Lomotey. (2021) Keratoconus in Africa: A systematic review and meta‐analysis. Ophthalmic and Physiological Optics 41:4, pages 736-747.
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Philipp Anders, Xuefei Song, Bence György, Nora Szentmary, Berthold Seitz & Zisis Gatzioufas. (2021) Effect of prolactin on normal and keratoconus human corneal stromal fibroblasts in vitro. PLOS ONE 16:4, pages e0249344.
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Ahmet Elbeyli & BengiEce Kurtul. (2021) Systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio levels are associated with keratoconus. Indian Journal of Ophthalmology 69:7, pages 1725.
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