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Gynecological Endocrinology Volume 24, 2008 - Issue 9
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Genetic variants in TCF7L2 and KCNJ11 genes in a Greek population with polycystic ovary syndrome

Panagiotis Christopoulos Second Department of Obstetrics and Gynecology, School of Medicine, University of Athens, Athens, GreeceCorrespondence[email protected]
,
George Mastorakos Second Department of Obstetrics and Gynecology, School of Medicine, University of Athens, Athens, Greece
,
Maria Gazouli Department of Biology, School of Medicine, University of Athens, Athens, Greece
,
Dimitrios Panidis Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece
,
Efthimios Deligeoroglou Second Department of Obstetrics and Gynecology, School of Medicine, University of Athens, Athens, Greece
,
Ilias Katsikis Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece
,
Konstantinos Papadias Second Department of Obstetrics and Gynecology, School of Medicine, University of Athens, Athens, Greece
,
Evanthia Diamandi-Kandarakis Endocrine Section, First Department of Internal Medicine, University of Athens, Athens, Greece
&
George Creatsas Second Department of Obstetrics and Gynecology, School of Medicine, University of Athens, Athens, Greece
 show all
Pages 486-490 | Received 27 Nov 2007, Accepted 10 Mar 2008, Published online: 07 Jul 2009

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Kateryna Mykhalchenko, Daria Lizneva, Tatiana Trofimova, Walidah Walker, Larisa Suturina, Michael P. Diamond & Ricardo Azziz. (2017) Genetics of polycystic ovary syndrome. Expert Review of Molecular Diagnostics 17:7, pages 723-733.
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Bin Liu, Hui-Ming Lv, Li-Nan Li, Lei Xia, Hong-Xiu Zhang, Ya-Juan Zhang & Lei Lei. (2012) Common variants of transcription factor 7-like 2 (TCF7L2) are associated with reduced insulin secretion in women with polycystic ovary syndrome. Gynecological Endocrinology 28:8, pages 594-597.
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Xiangdong Liu, Li Li, Zi-Jiang Chen, Zhiming Lu, Yuhua Shi & Yueran Zhao. (2010) Genetic variants of cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1 and transcription factor 7-like 2 are not associated with polycystic ovary syndrome in Chinese women. Gynecological Endocrinology 26:2, pages 129-134.
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Articles from other publishers (27)

Aya Badeea Ismail, Marwan ’Mohammad Saeed’ Naji, İnci Nebih, Gulten Tuncel, Burcu Ozbakir, Sehime Gulsun Temel, Pinar Tulay, Gamze Mocan & Mahmut Cerkez Ergoren. (2022) The expression profile of WNT/β-catanin signalling genes in human oocytes obtained from polycystic ovarian syndrome (PCOS) patients. Zygote 30:4, pages 536-542.
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Haigang Ding, Juan Zhang, Feng Zhang, Songou Zhang, Xiaozhen Chen, Wenqing Liang & Qiong Xie. (2021) Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome. Frontiers in Endocrinology 12.
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Andreas Grigoriadis, Symela Koutounidou, Ismo Räisänen, Minas Arsenakis & Dimitra Sakellari. (2021) Interaction between TCF7L2 rs7903146 Genotype, HbA1c Levels, and the Periodontal Status of Dental Patients. European Journal of Dentistry 15:03, pages 495-501.
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F. Ramezani Tehrani, M. Zarkesh, M. Tohidi, F. Azizi & A. Zadeh-Vakili. (2017) Is the association between insulin resistance and diabetogenic haematopoietically expressed homeobox (HHEX) polymorphism (rs1111875) affected by polycystic ovary syndrome status?. Reproduction, Fertility and Development 29:4, pages 670.
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Katarzyna Ożegowska, Anna Bogacz, Joanna Bartkowiak‑Wieczorek, Agnieszka Seremak‑Mrozikiewicz & Leszek Pawelczyk. (2016) Association between the angiotensin converting enzyme gene insertion/deletion polymorphism and metabolic disturbances in women with polycystic ovary syndrome. Molecular Medicine Reports.
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Michelle R. Jones & Mark O. Goodarzi. (2016) Genetic determinants of polycystic ovary syndrome: progress and future directions. Fertility and Sterility 106:1, pages 25-32.
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Ye Tian, Wei Zhang, Shigang Zhao, Yinhua Sun, Yuehong Bian, Tailai Chen, Yanzhi Du, Jiangtao Zhang, Zhao Wang, Tao Huang, Yingqian Peng, Ping Yang, Han Zhao & Zi-Jiang Chen. (2016) FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome. Scientific Reports 6:1.
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Ramon Bossardi Ramos, Vitor Costa Fabris, Let?cia de Almeida Brondani & Poli Mara Spritzer. (2015) Association between rs7903146 and rs12255372 polymorphisms of transcription factor 7-like 2 gene and polycystic ovary syndrome: a systematic review and meta-analysis. Endocrine 49:3, pages 635-642.
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M. Aktaruzzam, M.S. Islam, M.M.R. Howlader, M.M. Hossain & M.SD. Islam. (2015) Role of KCNJ11 Gene Polymorphisms and Risk of Type 2 Diabetes Mellitus. Pharmacologia 6:5, pages 149-159.
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Polin Haghvirdizadeh, Zahurin Mohamed, Nor Azizan Abdullah, Pantea Haghvirdizadeh, Monir Sadat Haerian & Batoul Sadat Haerian. (2015) KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus. Journal of Diabetes Research 2015, pages 1-9.
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Wen-Jing ShenTian-Ren LiYan-Jie HuHong-Bo LiuMin Song. (2014) Relationships Between TCF7L2 Genetic Polymorphisms and Polycystic Ovary Syndrome Risk: A Meta-Analysis . Metabolic Syndrome and Related Disorders 12:4, pages 210-219.
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Lin Lin, Jing Yang, Yan Ding, Jing Wang & Liu Ting. (2014) Genetic Polymorphisms of TCF7L2 Lack Influence on Risk of the Polycystic Ovary Syndrome - a Systemic Analysis. Asian Pacific Journal of Cancer Prevention 15:7, pages 3331-3333.
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Polin Haghvirdizadeh, Zahurin Mohamed, Nor Azizan Abdullah, Pantea Haghvirdizadeh, Monir Sadat Haerian & Batoul Sadat Haerian. (2014) KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus. Journal of Diabetes Research 2014, pages 1-9.
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A. Ben-Salem, M. Ajina, M. Suissi, H.S. Daher, W.Y. Almawi & T. Mahjoub. (2014) Polymorphisms of transcription factor-7-like 2 (TCF7L2) gene in Tunisian women with polycystic ovary syndrome (PCOS). Gene 533:2, pages 554-557.
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Michelle Zorrilla & Alexander N. Yatsenko. (2013) The Genetics of Infertility: Current Status of the Field. Current Genetic Medicine Reports 1:4, pages 247-260.
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George Paltoglou, George Tavernarakis, Panagiotis Christopoulos, Margarita Vlassi, Maria Gazouli, Efthimios Deligeoroglou, George Creatsas & George Mastorakos. (2013) PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenaemia. Clinical Endocrinology 79:2, pages 259-266.
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Gülüm Kosova & Margrit Urbanek. (2013) Genetics of the polycystic ovary syndrome. Molecular and Cellular Endocrinology 373:1-2, pages 29-38.
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R. Saxena & C. K. Welt. (2012) Polycystic ovary syndrome is not associated with genetic variants that mark risk of type 2 diabetes. Acta Diabetologica 50:3, pages 451-457.
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Jin Ju Kim, Young Min Choi, Young Min Cho, Min A. Hong, Soo Jin Chae, Kyu Ri Hwang, Seung Sik Hwang, Sang Ho Yoon & Shin Yong Moon. (2012) Polycystic ovary syndrome is not associated with polymorphisms of the TCF7L2 , CDKAL1 , HHEX , KCNJ11 , FTO and SLC30A8 genes . Clinical Endocrinology 77:3, pages 439-445.
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Kieran J. Guinan. (2011) Worldwide Distribution of Type II Diabetes-Associated TCF7L2 SNPs: Evidence for Stratification in Europe. Biochemical Genetics 50:3-4, pages 159-179.
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Thomas M Barber & Stephen Franks. (2012) The Link between Polycystic Ovary Syndrome and both Type 1 and Type 2 Diabetes Mellitus: What Do we Know Today?. Women's Health 8:2, pages 147-154.
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Michelle R. Jones, Angela K. Chua, Emebet A. Mengesha, Kent D. Taylor, Yii-Der I. Chen, Xiaohui Li, Ronald M. Krauss, Jerome I. Rotter, Richard S. Legro, Ricardo Azziz & Mark O. Goodarzi. (2012) Metabolic and cardiovascular genes in polycystic ovary syndrome: A candidate-wide association study (CWAS). Steroids 77:4, pages 317-322.
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B. C. J. M. Fauser, K. Diedrich, P. Bouchard, F. Dominguez, M. Matzuk, S. Franks, S. Hamamah, C. Simon, P. Devroey, D. Ezcurra & C. M. Howles. (2011) Contemporary genetic technologies and female reproduction. Human Reproduction Update 17:6, pages 829-847.
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Lu KeYe-Na CheYun-xia CaoXiao-Ke WuYa-Li HuHai-xiang SunFeng-jing LiangJing SunLong YiYong Wang. (2010) Polymorphisms of the HSD17B6 and HSD17B5 Genes in Chinese Women with Polycystic Ovary Syndrome. Journal of Women's Health 19:12, pages 2227-2232.
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Onder Celik, Elif Yesilada, Seyma Hascalik, Nilufer Celik, Ibrahim Sahin, Lezzan Keskin & Elif Ozerol. (2010) Angiotensin-converting enzyme gene polymorphism and risk of insulin resistance in PCOS. Reproductive BioMedicine Online 20:4, pages 492-498.
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Pei Xu, Yena Che, Yunxia Cao, XiaoKe Wu, Haixiang Sun, Fengjing Liang, Jing Sun, Lu Ke, Long Yi & Yong Wang. (2009) Polymorphisms of TCF7L2 and HHEX genes in Chinese women with polycystic ovary syndrome. Journal of Assisted Reproduction and Genetics 27:1, pages 23-28.
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. (2009) Current World Literature. Current Opinion in Obstetrics & Gynecology 21:6, pages 541-549.
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