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Banafsheh Jafari Azad, Elnaz Daneshzad, Ali Pasha Meysamie & Fariba Koohdani. (2021) Chronic and acute effects of cocoa products intake on arterial stiffness and platelet count and function: A systematic review and dose-response Meta-analysis of randomized clinical trials. Critical Reviews in Food Science and Nutrition 61:3, pages 357-379.
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Quintino Reis De Araujo, James Nascimento Gattward, Suzana Almoosawi, Maria das Graças Conceição Parada Costa Silva, Paulo Alfredo De Santana Dantas & Quintino Reis De Araujo Júnior. (2016) Cocoa and Human Health: From Head to Foot—A Review. Critical Reviews in Food Science and Nutrition 56:1, pages 1-12.
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Neela Badrie, Frances Bekele, Elzbieta Sikora & Marek Sikora. (2015) Cocoa Agronomy, Quality, Nutritional, and Health Aspects. Critical Reviews in Food Science and Nutrition 55:5, pages 620-659.
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Jiyoung Kim, Jaekyoon Kim, Jaesung Shim, Chang
Yong Lee, Ki
Won Lee & Hyong
Joo Lee. (2014) Cocoa Phytochemicals: Recent Advances in Molecular Mechanisms on Health. Critical Reviews in Food Science and Nutrition 54:11, pages 1458-1472.
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RobertaR. Holt, Christian Heiss, Malte Kelm & CarlL. Keen. (2012) The Potential of Flavanol and Procyanidin Intake to Influence Age-Related Vascular Disease. Journal of Nutrition in Gerontology and Geriatrics 31:3, pages 290-323.
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Majed A. Refaai, Eugene Frenkel & Ravi Sarode. (2010) Platelet aggregation responses vary over a period of time in healthy controls. Platelets 21:6, pages 460-463.
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Khalid Rahman. (2007) Studies on free radicals, antioxidants, and co-factors. Clinical Interventions in Aging 2:2, pages 219-236.
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Yvonne Steffen, Tankred Schewe & Helmut Sies. (2006) Myeloperoxidase-mediated LDL oxidation and endothelial cell toxicity of oxidized LDL: attenuation by (−)-epicatechin. Free Radical Research 40:10, pages 1076-1085.
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H. Mani, K. Kirchmayr, C. Kläffling, M. Schindewolf, B. Luxembourg, B. Linnemann & E. Lindhoff-Last. (2004) Influence of blood collection techniques on platelet function. Platelets 15:5, pages 315-318.
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Articles from other publishers (66)
Naveen Anand Seecheran, Darin Sukha, Kathryn Grimaldos, Gabriella Grimaldos, Srivane Richard, Aleena Ishmael, Ceylon Gomes, Lirmala Kampradi, Rajeev Seecheran, Valmiki Seecheran, Lakshmipathi Peram, Darren Dookeeram, Stanley Giddings, Sherry Sandy, Anil Ramlackhansingh, Sadi Raza, Pathmanathan Umaharan, Antonio Tello-Montoliu & David Schneider. (2022)
Effect of cocoa (
Theobroma cacao
L.) on platelet function testing profiles in patients with coronary artery disease: ECLAIR pilot study
. Open Heart 9:2, pages e002066.
Crossref
Crossref
Reema Singh, Ram B. Singh, Viliam Mojto, Dominik Pella, Jan Fedacko, Viola Vargova, Krasimira Hristova, Agnieszka Wilczynska, Maria Mojtova & Anna Gvozdjáková. 2022. Functional Foods and Nutraceuticals in Metabolic and Non-Communicable Diseases. Functional Foods and Nutraceuticals in Metabolic and Non-Communicable Diseases
279
299
.
Guo-Chao Zhong, Tian-Yang Hu, Peng-Fei Yang, Yang Peng, Jing-Jing Wu, Wei-Ping Sun, Long Cheng & Chun-Rui Wang. (2021) Chocolate consumption and all-cause and cause-specific mortality in a US population: a post hoc analysis of the PLCO cancer screening trial. Aging 13:14, pages 18564-18585.
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Jun-ying Jia, Er-huan Zang, Li-juan Lv, Qin-yu Li, Chun-hua Zhang, Ying Xia, Lei Zhang, Lian-sheng Dang & Min-hui Li. (2021) Flavonoids in myocardial ischemia-reperfusion injury: Therapeutic effects and mechanisms. Chinese Herbal Medicines 13:1, pages 49-63.
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Crossref
Thomas Sinegre, Dorian Teissandier, Dragan Milenkovic, Christine Morand & Aurélien Lebreton. (2019) Epicatechin influences primary hemostasis, coagulation and fibrinolysis. Food & Function 10:11, pages 7291-7298.
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Crossref
Anna Gvozdjakova, Reema Singh, Ram B. Singh, Toru Takahashi, Jan Fedacko, Krasimira Hristova, Agnieszka Wilczynska, Mária Mojtová & Viliam Mojto. 2019. The Role of Functional Food Security in Global Health. The Role of Functional Food Security in Global Health
317
345
.
Martina Montagnana, Elisa Danese, Donato Angelino, Pedro Mena, Alice Rosi, Marco Benati, Matteo Gelati, Gian Luca Salvagno, Emmanuel J. Favaloro, Daniele Del Rio & Giuseppe Lippi. (2018) Dark chocolate modulates platelet function with a mechanism mediated by flavan-3-ol metabolites. Medicine 97:49, pages e13432.
Crossref
Crossref
Asim K. Duttaroy. 2018. Nutraceuticals and Human Blood Platelet Function. Nutraceuticals and Human Blood Platelet Function
171
190
.
Tracie D. Locklear, Gail B. Mahady, Joanna Michel, Jillian De Gezelle, Angela I. Calderón, Jordan Alma McLeroy, Jesse Alice McLeroy, Brian J. Doyle, Esperanza J. Carcache de Blanco, Kelvin Nuñez Martinez & Alice L. Perez. 2018. Maternal Death and Pregnancy-Related Morbidity Among Indigenous Women of Mexico and Central America. Maternal Death and Pregnancy-Related Morbidity Among Indigenous Women of Mexico and Central America
63
111
.
Daniel A. Steinhaus, Elizabeth Mostofsky, Emily B. Levitan, Kirsten S. Dorans, Niclas Håkansson, Alicja Wolk & Murray A. Mittleman. (2017) Chocolate intake and incidence of heart failure: Findings from the Cohort of Swedish Men. American Heart Journal 183, pages 18-23.
Crossref
Crossref
Carlo Dal Lin, Marco Silvestro, Raffaele Migliorini, Francesco Tona & Massimo Fioranelli. 2017. Integrative Cardiology. Integrative Cardiology
203
221
.
Susanne Voelter-Mahlknecht. (2016) Epigenetic associations in relation to cardiovascular prevention and therapeutics. Clinical Epigenetics 8:1.
Crossref
Crossref
Eleni Kokkou, Gerasimos Siasos, Georgios Georgiopoulos, Evangelos Oikonomou, Aleksis Verveniotis, Manolis Vavuranakis, Konstantinos Zisimos, Aris Plastiras, Maria-Eleni Kollia, Christodoulos Stefanadis, Athanasios G. Papavassiliou & Dimitris Tousoulis. (2016) The impact of dietary flavonoid supplementation on smoking-induced inflammatory process and fibrinolytic impairment. Atherosclerosis 251, pages 266-272.
Crossref
Crossref
Gurvinder Rull, Zetty N. Mohd-Zain, Julian Shiel, Martina H. Lundberg, David J. Collier, Atholl Johnston, Timothy D. Warner & Roger Corder. (2015) Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation. Vascular Pharmacology 71, pages 70-78.
Crossref
Crossref
T. Walter, J. Grüttner, M. Borggrefe & S. Swoboda. (2015) Schokolade, Alkohol und KaffeeChocolate, alcohol and coffee. Der Kardiologe 9:3, pages 253-264.
Crossref
Crossref
Ilaria Peluso, Maura Palmery & Mauro Serafini. (2015) Effect of cocoa products and flavanols on platelet aggregation in humans: a systematic review. Food & Function 6:7, pages 2128-2134.
Crossref
Crossref
Paulo Zielinsky, Felipe V. Martignoni & Izabele Vian. (2014) Deleterious effects of maternal ingestion of cocoa upon fetal ductus arteriosus in late pregnancy. Frontiers in Pharmacology 5.
Crossref
Crossref
E.M. Bachmair, L.M. Ostertag, X. Zhang & B. de Roos. (2014) Dietary manipulation of platelet function. Pharmacology & Therapeutics 144:2, pages 97-113.
Crossref
Crossref
Connie H. Miller, Anne S. Rice, Katherine Garrett & Sidney F. Stein. (2014) Gender, race and diet affect platelet function tests in normal subjects, contributing to a high rate of abnormal results. British Journal of Haematology 165:6, pages 842-853.
Crossref
Crossref
Nasiruddin Khan, Olha Khymenets, Mireia Urpí-Sardà, Sara Tulipani, Mar Garcia-Aloy, María Monagas, Ximena Mora-Cubillos, Rafael Llorach & Cristina Andres-Lacueva. (2014) Cocoa Polyphenols and Inflammatory Markers of Cardiovascular Disease. Nutrients 6:2, pages 844-880.
Crossref
Crossref
Laura S. Latham, Zeb K. Hensen & Deborah S. Minor. (2014) Chocolate-Guilty Pleasure or Healthy Supplement?. The Journal of Clinical Hypertension 16:2, pages 101-106.
Crossref
Crossref
Roland von Känel, Rebecca Meister, Monika Stutz, Petra Kummer, Angela Arpagaus, Susanne Huber, Ulrike Ehlert & Petra Wirtz. (2017) Effects of dark chocolate consumption on the prothrombotic response to acute psychosocial stress in healthy men. Thrombosis and Haemostasis 112:12, pages 1151-1158.
Crossref
Crossref
Davide Grassi & Claudio Ferri. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease
1009
1023
.
Wendy J Hollands, Shikha Saha, Osman Hayran, Nadiya Boyko, Maria Glibetic, Aleksandra Konic-Ristic, Mariam Jorjadze & Paul A Kroon. (2013)
Lack of effect of bioactive-rich extracts of pomegranate, persimmon, nettle, dill, kale and
Sideritis
and isolated bioactives on platelet function
. Journal of the Science of Food and Agriculture 93:14, pages 3588-3594.
Crossref
Crossref
Sara Arranz, Palmira Valderas-Martinez, Gemma Chiva-Blanch, Rosa Casas, Mireia Urpi-Sarda, Rosa M. Lamuela-Raventos & Ramon Estruch. (2013) Cardioprotective effects of cocoa: Clinical evidence from randomized clinical intervention trials in humans. Molecular Nutrition & Food Research 57:6, pages 936-947.
Crossref
Crossref
B. Maneesha Silva, Anna E. Hosman, Hannah L. Devlin & Claire L. Shovlin. (2013) Lifestyle and Dietary Influences on Nosebleed Severity in Hereditary Hemorrhagic Telangiectasia. The Laryngoscope 123:5, pages 1092-1099.
Crossref
Crossref
Piet Borgdorff & Geert Jan Tangelder. (2013) Migraine Relief by Chilis and Other Alternative Medications - Caused by Platelet Inhibition?. Headache: The Journal of Head and Face Pain 53:2, pages 386-387.
Crossref
Crossref
Mark F. McCarty. (2013) Dietary nitrate and reductive polyphenols may potentiate the vascular benefit and alleviate the ulcerative risk of low-dose aspirin. Medical Hypotheses 80:2, pages 186-190.
Crossref
Crossref
Emad Al-Dujaili, Catherine Tsang & Suzana Almoosawi. 2013. Chocolate in Health and Nutrition. Chocolate in Health and Nutrition
341
353
.
Nancy J. Correa-Matos & Catherine Christie. 2013. Chocolate in Health and Nutrition. Chocolate in Health and Nutrition
289
301
.
Susanna C. LarssonJarmo VirtamoAlicja Wolk. (2012) Chocolate consumption and risk of stroke. Neurology 79:12, pages 1223-1229.
Crossref
Crossref
Piet Borgdorff & Geert Jan Tangelder. (2012) Migraine: Possible Role of Shear‐Induced Platelet Aggregation With Serotonin Release. Headache: The Journal of Head and Face Pain 52:8, pages 1298-1318.
Crossref
Crossref
Vèronique Habauzit & Christine Morand. (2011) Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: an update for clinicians. Therapeutic Advances in Chronic Disease 3:2, pages 87-106.
Crossref
Crossref
R. CARNEVALE, L. LOFFREDO, P. PIGNATELLI, C. NOCELLA, S. BARTIMOCCIA, S. DI SANTO, F. MARTINO, E. CATASCA, L. PERRI & F. VIOLI. (2012) Dark chocolate inhibits platelet isoprostanes via NOX2 down‐regulation in smokers. Journal of Thrombosis and Haemostasis 10:1, pages 125-132.
Crossref
Crossref
T. K. LimT. K. Lim. 2012. Edible Medicinal And Non Medicinal Plants. Edible Medicinal And Non Medicinal Plants
208
251
.
Isabella Sudano, Andreas J. Flammer, Georg Noll & Roberto Corti. 2012. Chocolate and Health. Chocolate and Health
103
113
.
Owais Khawaja, J. Michael Gaziano & Luc Djoussé. (2011) Chocolate and Coronary Heart Disease: A Systematic Review. Current Atherosclerosis Reports 13:6, pages 447-452.
Crossref
Crossref
L. Fernández-Murga, J.J. Tarín, M.A. García-Perez & A. Cano. (2011) The impact of chocolate on cardiovascular health. Maturitas 69:4, pages 312-321.
Crossref
Crossref
Ingrid A.-L Persson, Karin Persson, Staffan Hägg & Rolf G G Andersson. (2011) Effects of Cocoa Extract and Dark Chocolate on Angiotensin-converting Enzyme and Nitric Oxide in Human Endothelial Cells and Healthy Volunteers–A Nutrigenomics Perspective. Journal of Cardiovascular Pharmacology 57:1, pages 44-50.
Crossref
Crossref
Ulf G. BronasDonald R. Dengel. (2010) Influence of Vascular Oxidative Stress and Inflammation on the Development and Progression of Atherosclerosis. American Journal of Lifestyle Medicine 4:6, pages 521-534.
Crossref
Crossref
Elizabeth MostofskyEmily B. LevitanAlicja WolkMurray A. Mittleman. (2010) Chocolate Intake and Incidence of Heart Failure. Circulation: Heart Failure 3:5, pages 612-616.
Crossref
Crossref
Lei Jia, Xuan Liu, Yong Yi Bai, Shao Hua Li, Kai Sun, Chen He & Rutai Hui. (2010) Short-term effect of cocoa product consumption on lipid profile: a meta-analysis of randomized controlled trials. The American Journal of Clinical Nutrition 92:1, pages 218-225.
Crossref
Crossref
Raika Koli, Iris Erlund, Antti Jula, Jukka Marniemi, Pirjo Mattila & Georg Alfthan. (2010) Bioavailability of Various Polyphenols from a Diet Containing Moderate Amounts of Berries. Journal of Agricultural and Food Chemistry 58:7, pages 3927-3932.
Crossref
Crossref
A. Spadafranca, C. Martinez Conesa, S. Sirini & G. Testolin. (2009) Effect of dark chocolate on plasma epicatechin levels, DNA resistance to oxidative stress and total antioxidant activity in healthy subjects. British Journal of Nutrition 103:7, pages 1008-1014.
Crossref
Crossref
Francesco VioliPasquale PignatelliStefania Basili. (2010) Nutrition, Supplements, and Vitamins in Platelet Function and Bleeding. Circulation 121:8, pages 1033-1044.
Crossref
Crossref
Mark F. McCarty, Jorge Barroso-Aranda & Francisco Contreras. (2010) Potential complementarity of high-flavanol cocoa powder and spirulina for health protection. Medical Hypotheses 74:2, pages 370-373.
Crossref
Crossref
Luisa M. Ostertag, Niamh O'Kennedy, Paul A. Kroon, Garry G. Duthie & Baukje de Roos. (2010) Impact of dietary polyphenols on human platelet function - A critical review of controlled dietary intervention studies. Molecular Nutrition & Food Research 54:1, pages 60-81.
Crossref
Crossref
Gerald Rimbach, Mona Melchin, Jennifer Moehring & Anika Wagner. (2009) Polyphenols from Cocoa and Vascular Health—A Critical Review. International Journal of Molecular Sciences 10:10, pages 4290-4309.
Crossref
Crossref
Roberto CortiAndreas J. FlammerNorman K. HollenbergThomas F. Lüscher. (2009) Cocoa and Cardiovascular Health. Circulation 119:10, pages 1433-1441.
Crossref
Crossref
Nina Rolf, Ralf Knoefler, Peter Bugert, Siegmund Gehrisch, Gabriele Siegert, Eberhard Kuhlisch & Meinolf Suttorp. (2009) Clinical and laboratory phenotypes associated with the aspirin-like defect: a study in 17 unrelated families. British Journal of Haematology 144:3, pages 416-424.
Crossref
Crossref
Manfredi Rizzo & Kaspar Berneis. (2008) Recent Insights on Dark Chocolate Consumption and Cardiovascular Risk. Southern Medical Journal 101:12, pages 1194.
Crossref
Crossref
Miruais S. Hamed, Steven Gambert, Kevin P. Bliden, Oscar Bailon, Singla Anand, Mark J. Antonino, Fatema Hamed, Udaya S. Tantry & Paul A. Gurbel. (2008) Dark Chocolate Effect on Platelet Activity, C-Reactive Protein and Lipid Profile: A Pilot Study. Southern Medical Journal 101:12, pages 1203-1208.
Crossref
Crossref
M. Mozaffarieh, M.C. Grieshaber, S. Orgül & J. Flammer. (2008) The Potential Value of Natural Antioxidative Treatment in Glaucoma. Survey of Ophthalmology 53:5, pages 479-505.
Crossref
Crossref
Bryan Bordeaux, Lisa R. Yanek, Taryn F. Moy, Linda W. White, Lewis C. Becker, Nauder Faraday & Diane M. Becker. (2007) Casual Chocolate Consumption and Inhibition of Platelet Function. Preventive Cardiology 10:4, pages 175-180.
Crossref
Crossref
Eric L Ding, Susan M Hutfless, Xin Ding & Saket Girotra. (2006) Chocolate and Prevention of Cardiovascular Disease: A Systematic Review. Nutrition & Metabolism 3:1.
Crossref
Crossref
A.C. Kaliora, G.V.Z. Dedoussis & H. Schmidt. (2006) Dietary antioxidants in preventing atherogenesis. Atherosclerosis 187:1, pages 1-17.
Crossref
Crossref
Stan Heptinstall, Jane May, Sue Fox, Catherine Kwik-Uribe & Lian Zhao. (2006) Cocoa Flavanols and Platelet and Leukocyte Function: Recent In Vitro and Ex Vivo Studies in Healthy Adults. Journal of Cardiovascular Pharmacology 47:Supplement 2, pages S197-S205.
Crossref
Crossref
Roberta R. Holt, Lucas Actis-Goretta, Tony Y. Momma & Carl L. Keen. (2006) Dietary Flavanols and Platelet Reactivity. Journal of Cardiovascular Pharmacology 47:Supplement 2, pages S187-S196.
Crossref
Crossref
Janice F. Wang-Polagruto, Amparo C. Villablanca, John A. Polagruto, Luke Lee, Roberta R. Holt, Heather R. Schrader, Jodi L. Ensunsa, Francene M. Steinberg, Harold H. Schmitz & Carl L. Keen. (2006) Chronic Consumption of Flavanol-rich Cocoa Improves Endothelial Function and Decreases Vascular Cell Adhesion Molecule in Hypercholesterolemic Postmenopausal Women. Journal of Cardiovascular Pharmacology 47:Supplement 2, pages S177-S186.
Crossref
Crossref
Charalambos Vlachopoulos, Nikolaos Alexopoulos & Christodoulos Stefanadis. (2006) Effect of dark chocolate on arterial function in healthy individuals: Cocoa instead of ambrosia?. Current Hypertension Reports 8:3, pages 205-211.
Crossref
Crossref
Mary B. Engler & Marguerite M. Engler. (2006) The Emerging Role of Flavonoid-Rich Cocoa and Chocolate in Cardiovascular Health and Disease. Nutrition Reviews 64:3, pages 109-118.
Crossref
Crossref
Merlin W. Ariefdjohan & Dennis A. Savaiano. (2005) Chocolate and Cardiovascular Health: Is It Too Good To Be True?. Nutrition Reviews 63:12, pages 427-430.
Crossref
Crossref
Christian Heiss, Petra Kleinbongard, Andrè Dejam, Sandra Perré, Hagen Schroeter, Helmut Sies & Malte Kelm. (2005) Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers. Journal of the American College of Cardiology 46:7, pages 1276-1283.
Crossref
Crossref
R. M. Lamuela-RaventósA. I. Romero-Pérez, C. Andrés-Lacueva & A. Tornero. (2016) Review: Health Effects of Cocoa Flavonoids. Food Science and Technology International 11:3, pages 159-176.
Crossref
Crossref
Helmut Sies, Tankred Schewe, Christian Heiss & Malte Kelm. (2005) Cocoa polyphenols and inflammatory mediators. The American Journal of Clinical Nutrition 81:1, pages 304S-312S.
Crossref
Crossref
Paul Harrison, Helen Segal, Charlene Furtado, Salim Verjee, Kampta Sukhu & Michael F. Murphy. (2004) High incidence of defective high-shear platelet function among platelet donors. Transfusion 44:5, pages 764-770.
Crossref
Crossref