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Platelets Volume 34, 2023 - Issue 1
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Research article

Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets

Sagar S. Matharu1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Cassidy S. Nordmann1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Kurtis R. Ottman1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Rahul Akkem1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Douglas Palumbo1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Denzel R. D. Cruz1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Kenneth Campbell2 Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
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Gail Sievert3 Center for Clinical Translational Science, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
,
Jamie Sturgill2 Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
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James Z. Porterfield4 Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
,
Smita Joshi5 Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
,
Hammodah R. Alfar5 Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
,
Chi Peng5 Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
,
Irina D. Pokrovskaya6 Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USAView further author information
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Jeffrey A. Kamykowski6 Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USAView further author information
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Jeremy P. Wood2 Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
,
Beth Garvy4 Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY, USAView further author information
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Maria A. Aronova1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
,
Sidney W. Whiteheart5 Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USAORCID Iconhttps://orcid.org/0000-0001-5577-0473View further author information
ORCID Icon,
Richard D. Leapman1 Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USAView further author information
&
Brian Storrie6 Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4644-2504View further author information
ORCID Icon show all
Article: 2264978 | Received 06 Jul 2023, Accepted 20 Sep 2023, Published online: 07 Nov 2023

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