Publication Cover
AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 26, 2014 - Issue 4
700
Views
62
CrossRef citations to date
0
Altmetric
Original Articles

The neurodevelopment of HIV-infected infants on HAART compared to HIV-exposed but uninfected infants

, &
Pages 497-504 | Received 29 Nov 2012, Accepted 04 Sep 2013, Published online: 14 Oct 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

N Comley-White, Joanne Potterton & Veronica Ntsiea. (2023) Disability, fatigue and peripheral neuropathy in adolescents with perinatal HIV infection. Vulnerable Children and Youth Studies 18:4, pages 517-529.
Read now
Nicolette Comley-White, Veronica Ntsiea & Joanne Potterton. (2023) Physical functioning in adolescents with perinatal HIV. AIDS Care 0:0, pages 1-10.
Read now
Nicolette Comley-White, Joanne Potterton & Veronica Ntsiea. (2022) The physical sequelae of growing into adolescence with perinatally acquired HIV: a scoping review. Physical Therapy Reviews 27:2, pages 158-168.
Read now
Stacy Maddocks, MZ Nakooda, Saul Cobbing, Jill Hanass-Hancock & Verusia Chetty. (2021) Perceptions of care and rehabilitation for children living with HIV in KwaZulu-Natal province, South Africa. Vulnerable Children and Youth Studies 16:2, pages 151-165.
Read now
Renate Strehlau, Tamryn van Aswegen, Megan Burke, Louise Kuhn & Joanne Potterton. (2020) A description of early neurodevelopment in a cohort of HIV-exposed uninfected children. AIDS Care 32:11, pages 1421-1428.
Read now
Ruili Li, Wei Wang, Yuanyuan Wang, Sönke Peters, Xiaodong Zhang & Hongjun Li. (2019) Effects of early HIV infection and combination antiretroviral therapy on intrinsic brain activity: a cross-sectional resting-state fMRI study. Neuropsychiatric Disease and Treatment 15, pages 883-894.
Read now
S. E. Brassell & J. Potterton. (2019) Prevalence of disability in HIV-infected children attending an urban paediatric HIV clinic in Johannesburg, South Africa. Vulnerable Children and Youth Studies 14:2, pages 95-115.
Read now
Tasvi Naik, Joanne Potterton, Gregory Bodley Firth, Kerry S. Wilson & Carolyn R. Humphries. (2018) A comparison of the clinical presentation of with HIV infected (HIVE) to uninfected (CP) children with spastic diplegia in South Africa. Vulnerable Children and Youth Studies 13:3, pages 195-206.
Read now
Helen Mebrahtu, Victoria Simms, Rudo Chingono, Zivai Mupambireyi, Helen A. Weiss, Patience Ndlovu, Ricky Malaba, Frances M. Cowan & Lorraine Sherr. (2018) Postpartum maternal mental health is associated with cognitive development of HIV-exposed infants in Zimbabwe: a cross-sectional study. AIDS Care 30:sup2, pages 74-82.
Read now
Robyn Jess Meissner, Jessica Ferguson, Caraleigh Otto, Pam Gretschel & Elelwani Ramugondo. (2017) A play-informed, caregiver-implemented, home-based intervention for HIV-positive children and their families living in low-income conditions in South Africa. World Federation of Occupational Therapists Bulletin 73:2, pages 83-87.
Read now
Charlotte Blokhuis, Neeltje A Kootstra, Matthan WA Caan & Dasja Pajkrt. (2016) Neurodevelopmental delay in pediatric HIV/AIDS: current perspectives. Neurobehavioral HIV Medicine 7, pages 1-13.
Read now

Articles from other publishers (50)

Esther Jebor Chongwo, Catherine J. Wedderburn, Moses Kachama Nyongesa, Antipa Sigilai, Paul Mwangi, Janet Thoya, Rachel Odhiambo, Katana Ngombo, Beatrice Kabunda, Charles R. Newton & Amina Abubakar. (2023) Neurocognitive outcomes of children exposed to and living with HIV aged 3–5 years in Kilifi, Kenya. Frontiers in Reproductive Health 5.
Crossref
Violeta J. Rodriguez, Demy Alfonso, Hannah VanLandingham, Sofia Kozlova, Zachary J. Resch, Jason R. Soble & Deborah L. Jones. (2023) Prevalence of neurodevelopmental delays in infants with perinatal HIV infection in comparison with HIV exposure in rural South Africa. AIDS 37:8, pages 1239-1245.
Crossref
Elise Davis-McFarland. 2023. Handbook of Speech-Language Therapy in Sub-Saharan Africa. Handbook of Speech-Language Therapy in Sub-Saharan Africa 315 341 .
Ruili Li, Yuxun Gao, Wei Wang, Zengxin Jiao, Bo Rao, Guangxue Liu & Hongjun Li. (2022) Altered gray matter structural covariance networks in drug-naïve and treated early HIV-infected individuals. Frontiers in Neurology 13.
Crossref
Monray E. Williams, Anicia Janse Van Rensburg, Du Toit Loots, Petrus J. W. Naudé & Shayne Mason. (2021) Immune Dysregulation Is Associated with Neurodevelopment and Neurocognitive Performance in HIV Pediatric Populations—A Scoping Review. Viruses 13:12, pages 2543.
Crossref
Sílvia Chaúque, Jyodi Mohole, Helton Zucula, Luisa Lambo, Anselmo Lisboa, Domitila Ferreira, Hanh Nguyen, Harshika Chowdhary, Belinda Macmillian, Beatriz Elias, Amir Seni & W Chris Buck. (2021) HIV Encephalopathy in ART-Naïve, Hospitalized Infants in Mozambique. Journal of Tropical Pediatrics 67:6.
Crossref
S. N. Saidkhodjaeva, E. N. Madjidova & K. Kh. Yuldashev. (2021) Diagnostic markers in the aspect of the development of HIV-encephalopathy in children. Journal Infectology 13:3, pages 55-61.
Crossref
Motlagabo Gladys Matseke, Robert A. C. Ruiter, Violeta J. Rodriguez, Karl Peltzer, Deborah L. Jones & Sibusiso Sifunda. (2021) Male Partner Involvement and Development of HIV-exposed Infants in Rural South Africa. AIDS and Behavior 25:9, pages 2712-2719.
Crossref
Vishwanath .Alok Hemal, Manju Nimesh, Meetu Singh & Sheetal Agarwal. (2021) Neurocognitive Lag in School-Aged Children Living With HIV in India and Its Relevance. Cureus.
Crossref
Reshma Sirajee, Andrea L. Conroy, Sophie Namasopo, Robert O. Opoka, Stephanie Lavoie, Sarah Forgie, Bukola O. Salami & Michael T. Hawkes. (2021) Growth Faltering and Developmental Delay in HIV-Exposed Uninfected Ugandan Infants: A Prospective Cohort Study. JAIDS Journal of Acquired Immune Deficiency Syndromes 87:1, pages 730-740.
Crossref
Jordan G. Schnoll, Brian Temsamrit, Daniel Zhang, Hongjun Song, Guo-li Ming & Kimberly M. Christian. (2019) Evaluating Neurodevelopmental Consequences of Perinatal Exposure to Antiretroviral Drugs: Current Challenges and New Approaches. Journal of Neuroimmune Pharmacology 16:1, pages 113-129.
Crossref
Manoj K. Sarma, Amrita Pal, Margaret A. Keller, Tamara Welikson, Joseph Ventura, David E. Michalik, Karin Nielsen-Saines, Jaime Deville, Andrea Kovacs, Eva Operskalski, Joseph A. Church, Paul M. Macey, Bharat Biswal & M. Albert Thomas. (2021) White matter of perinatally HIV infected older youths shows low frequency fluctuations that may reflect glial cycling. Scientific Reports 11:1.
Crossref
Nicolette Comley-White, Joanne Potterton & Veronica Ntsiea. (2021) Physical sequelae of growing into adolescence with perinatally acquired HIV: a scoping review protocol. JBI Evidence Synthesis 19:11, pages 3149-3154.
Crossref
Christelle Ackermann, Savvas Andronikou, Muhammad G. Saleh, Martin Kidd, Mark F. Cotton, Ernesta M. Meintjes & Barbara Laughton. (2020) Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments. AIDS Research and Therapy 17:1.
Crossref
Violeta J. Rodriguez, Miriam Zegarac, Dominique L. La Barrie, Manasi Soni Parrish, Gladys Matseke, Karl Peltzer & Deborah L. Jones. (2020) Validation of the Bayley Infant Neurodevelopmental Screener Among HIV-Exposed Infants in Rural South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes 85:4, pages 507-516.
Crossref
Marina White & Kristin L. Connor. (2020) In Utero HIV Exposure and the Early Nutritional Environment Influence Infant Neurodevelopment: Findings from an Evidenced Review and Meta-Analysis. Nutrients 12:11, pages 3375.
Crossref
Christina A Laurenzi, Sarah Skeen, Sarah Gordon, Olamide Akin‐Olugbade, Nina Abrahams, Melissa Bradshaw, Amanda Brand, Stefani du Toit, G J Melendez‐Torres, Mark Tomlinson, Chiara Servili, Tarun Dua & David A Ross. (2020) Preventing mental health conditions in adolescents living with HIV: an urgent need for evidence. Journal of the International AIDS Society 23:S5.
Crossref
Jennifer Jao, Deborah Kacanek, Wendy Yu, Paige L. Williams, Kunjal Patel, Sandra Burchett, Gwendolyn Scott, Elaine J. Abrams, Rhoda S. Sperling, Russell B. Van Dyke, Renee Smith & Kathleen Malee. (2020) Neurodevelopment of HIV-Exposed Uninfected Infants Born to Women With Perinatally Acquired HIV in the United States. JAIDS Journal of Acquired Immune Deficiency Syndromes 84:2, pages 213-219.
Crossref
Thomas Struyf, Queen Dube, Elizabeth A. Cromwell, Anna D. Sheahan, Robert S. Heyderman & Annelies Van Rie. (2020) The effect of HIV infection and exposure on cognitive development in the first two years of life in Malawi. European Journal of Paediatric Neurology 25, pages 157-164.
Crossref
Barbara Laughton, Shalena Naidoo, Els F.M.T. Dobbels, Michael J. Boivin, Anita Janse van Rensburg, Richard H. Glashoff, Gert U. Van Zyl, Mariana Kruger & Mark F. Cotton. (2019) Neurodevelopment at 11 months after starting antiretroviral therapy within 3 weeks of life. Southern African Journal of HIV Medicine 20:1.
Crossref
Manoj K. Sarma, Margaret A. Keller, Paul M. Macey, David E. Michalik, Judy Hayes, Karin Nielsen-Saines, Jaime Deville, Joseph A. Church, Irwin Walot & M. Albert Thomas. (2019) White matter microstructure among perinatally HIV-infected youth: a diffusion tensor imaging study. Journal of NeuroVirology 25:3, pages 313-323.
Crossref
Sarah F. Benki-Nugent, Ira Martopullo, Tony Laboso, Nancy Tamasha, Dalton C. Wamalwa, Kenneth Tapia, Agnes Langat, Elizabeth Maleche-Obimbo, Christina M. Marra, Paul Bangirana, Michael J. Boivin & Grace C. John-Stewart. (2019) High Plasma Soluble CD163 During Infancy Is a Marker for Neurocognitive Outcomes in Early-Treated HIV-Infected Children. JAIDS Journal of Acquired Immune Deficiency Syndromes 81:1, pages 102-109.
Crossref
Watsamon Jantarabenjakul, Weerasak Chonchaiya, Thanyawee Puthanakit, Tuangtip Theerawit, Jesdaporn Payapanon, Jiratchaya Sophonphan, Montida Veeravigom, Neda Jahanshad, Paul M Thompson, Jintanat Ananworanich, Kathleen Malee & Chitsanu Pancharoen. (2019) Low risk of neurodevelopmental impairment among perinatally acquired HIV ‐infected preschool children who received early antiretroviral treatment in Thailand . Journal of the International AIDS Society 22:4.
Crossref
Elelwani Ramugondo, Anande Ferreira, Donna Chung & Reinie Cordier. (2018) A Feasibility RCT Evaluating a Play-Informed, Caregiver-Implemented, Home-Based Intervention to Improve the Play of Children Who Are HIV Positive. Occupational Therapy International 2018, pages 1-15.
Crossref
Violeta J. Rodriguez, Karl Peltzer, Gladys Matseke, Stephen M. Weiss, Agnes Shine & Deborah L. Jones. (2018) Pre- and postnatal exposure to intimate partner violence among South African HIV-infected mothers and infant developmental functioning at 12 months of age. Archives of Women's Mental Health 21:6, pages 707-713.
Crossref
Laurén A. Gómez, Claudia S. Crowell, Irene Njuguna, Lisa M. Cranmer, Dalton Wamalwa, Daisy Chebet, Vincent Otieno, Elizabeth Maleche-Obimbo, Melissa GladstoneGrace John-Stewart & Sarah Benki-Nugent. (2018) Improved Neurodevelopment After Initiation of Antiretroviral Therapy in Human Immunodeficiency Virus–infected Children. Pediatric Infectious Disease Journal 37:9, pages 916-922.
Crossref
Violeta J. Rodriguez, Gladys Matseke, Ryan Cook, Seanna Bellinger, Stephen M. Weiss, Maria L. Alcaide, Karl Peltzer, Doyle Patton, Maria Lopez & Deborah L. Jones. (2017) Infant Development and Pre- and Post-partum Depression in Rural South African HIV-Infected Women. AIDS and Behavior 22:6, pages 1766-1774.
Crossref
Frances C. Robertson, Martha J. Holmes, Mark F. Cotton, Els Dobbels, Francesca Little, Barbara Laughton, André J. W. van der Kouwe & Ernesta M. Meintjes. (2018) Perinatal HIV Infection or Exposure Is Associated With Low N-Acetylaspartate and Glutamate in Basal Ganglia at Age 9 but Not 7 Years. Frontiers in Human Neuroscience 12.
Crossref
Sylvia Fitting, Kristen A. McLaurin, Rosemarie M. Booze & Charles F. Mactutus. (2017) Dose‐dependent neurocognitive deficits following postnatal day 10 HIV‐1 viral protein exposure: Relationship to hippocampal anatomy parameters. International Journal of Developmental Neuroscience 65:1, pages 66-82.
Crossref
Emmanuel C. Nwosu, Frances C. Robertson, Martha J. Holmes, Mark F. Cotton, Els Dobbels, Francesca Little, Barbara Laughton, Andre van der Kouwe & Ernesta M. Meintjes. (2017) Altered brain morphometry in 7-year old HIV-infected children on early ART. Metabolic Brain Disease 33:2, pages 523-535.
Crossref
Jadrana T. F. Toich, Paul A. Taylor, Martha J. Holmes, Suril Gohel, Mark F. Cotton, Els Dobbels, Barbara Laughton, Francesca Little, Andre J. W. van der Kouwe, Bharat Biswal & Ernesta M. Meintjes. (2018) Functional Connectivity Alterations between Networks and Associations with Infant Immune Health within Networks in HIV Infected Children on Early Treatment: A Study at 7 Years. Frontiers in Human Neuroscience 11.
Crossref
L. Sherr, I. S. Hensels, M. Tomlinson, S. Skeen & A. Macedo. (2017) Cognitive and physical development in HIV‐positive children in South Africa and Malawi: A community‐based follow‐up comparison study. Child: Care, Health and Development 44:1, pages 89-98.
Crossref
Sarah Benki-Nugent, Dalton Wamalwa, Agnes Langat, Kenneth Tapia, Judith Adhiambo, Daisy Chebet, Helen Moraa Okinyi & Grace John-Stewart. (2017) Comparison of developmental milestone attainment in early treated HIV-infected infants versus HIV-unexposed infants: a prospective cohort study. BMC Pediatrics 17:1.
Crossref
Steven R. Randall, Christopher M. R. Warton, Martha J. Holmes, Mark F. Cotton, Barbara Laughton, Andre J. W. van der Kouwe & Ernesta M. Meintjes. (2017) Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART. Frontiers in Neuroanatomy 11.
Crossref
Daynia E. Ballot, Tanusha Ramdin, David Rakotsoane, Faustine Agaba, Victor A. Davies, Tobias Chirwa & Peter A. Cooper. (2017) Use of the Bayley Scales of Infant and Toddler Development, Third Edition, to Assess Developmental Outcome in Infants and Young Children in an Urban Setting in South Africa. International Scholarly Research Notices 2017, pages 1-5.
Crossref
Daynia Elizabeth Ballot, Tanusha Ramdin, David Rakotsoane, Faustine Agaba, Tobias Chirwa, Victor Alan Davies & Peter Alan Cooper. (2017) Assessment of developmental outcome in very low birth weight infants in Southern Africa using the Bayley Scales of Infant Development (III). BMJ Paediatrics Open 1:1, pages e000091.
Crossref
Chandy C. JohnMaureen M. BlackCharles A. NelsonIIIIII. (2017) Neurodevelopment: The Impact of Nutrition and Inflammation During Early to Middle Childhood in Low-Resource Settings. Pediatrics 139:Supplement_1, pages S59-S71.
Crossref
Theresa N Mann, Kirsten A Donald, Barbara Laughton, Robert P Lamberts & Nelleke G Langerak. (2017) HIV encephalopathy with bilateral lower limb spasticity: upper limb motor function and level of activity and participation. Developmental Medicine & Child Neurology 59:4, pages 412-419.
Crossref
Kristen A. McLaurin, Rosemarie M. Booze & Charles F. Mactutus. (2016) Selective developmental alterations in The HIV-1 transgenic rat: Opportunities for diagnosis of pediatric HIV-1. Journal of NeuroVirology 23:1, pages 87-98.
Crossref
Amina Abubakar. 2017. Handbook of Applied Developmental Science in Sub-Saharan Africa. Handbook of Applied Developmental Science in Sub-Saharan Africa 117 131 .
Claudia S. Crowell & Kathleen Malee. 2017. Global Virology II - HIV and NeuroAIDS. Global Virology II - HIV and NeuroAIDS 257 282 .
Eric J. Dziuban & Emilia D. Rivadeneira. (2016) Universal Antiretroviral Treatment Eligibility for Children and Adolescents Living With HIV. Pediatric Infectious Disease Journal 35:11, pages 1225-1228.
Crossref
Kayla A. Musielak & Jodene Goldenring Fine. (2015) An Updated Systematic Review of Neuroimaging Studies of Children and Adolescents with Perinatally Acquired HIV. Journal of Pediatric Neuropsychology 2:1-2, pages 34-49.
Crossref
J. Potterton, N. Hilburn & R. Strehlau. (2016) Developmental status of preschool children receiving cART: a descriptive cohort study. Child: Care, Health and Development 42:3, pages 410-414.
Crossref
Jintanat Ananworanich, Diane Melvin, Jose T.R. Amador, Tristan Childs, Gabriela Medin, Valentina Boscolo, Alexandra Compagnucci, Suparat Kanjanavanit, Samuel Montero & Diana M. Gibb. (2016) Neurocognition and quality of life after reinitiating antiretroviral therapy in children randomized to planned treatment interruption. AIDS 30:7, pages 1075-1081.
Crossref
Amara E. Ezeamama, Florence N. Kizza, Sarah K. Zalwango, Allan K. Nkwata, Ming Zhang, Mariana L. Rivera, Juliet N. Sekandi, Robert Kakaire, Noah Kiwanuka & Christopher C. Whalen. (2016) Perinatal HIV Status and Executive Function During School-Age and Adolescence. Medicine 95:17, pages e3438.
Crossref
Heather Carryl, Melanie Swang, Jerome Lawrence, Kimberly Curtis, Herman Kamboj, Koen K. A. Van Rompay, Kristina De Paris & Mark W. Burke. (2015) Of Mice and Monkeys: Can Animal Models Be Utilized to Study Neurological Consequences of Pediatric HIV-1 Infection?. ACS Chemical Neuroscience 6:8, pages 1276-1289.
Crossref
Amina Abubakar. (2014) Biomedical Risk, Psychosocial Influences, and Developmental Outcomes: Lessons From the Pediatric HIV Population in Africa. New Directions for Child and Adolescent Development 2014:146, pages 23-41.
Crossref
Mary S. Ngoma, Jennifer A. Hunter, Jessica A. Harper, Paige T. Church, Scholastica Mumba, Mulapati Chandwe, Hélène C.F. Côté, Arianne Y.K. Albert, Mary-Lou Smith, Chisomo Selemani, Paul A. Sandstrom, Lucas Bandenduck, Utsile Ndlovu, Sara Khan, Lina Roa & Michael S. Silverman. (2014) Cognitive and language outcomes in HIV-uninfected infants exposed to combined antiretroviral therapy in utero and through extended breast-feeding. AIDS 28:Supplement 3, pages S323-S330.
Crossref
Kirsten Ann Donald, Jackie Hoare, Brian Eley & Jo M. Wilmshurst. (2014) Neurologic Complications of Pediatric Human Immunodeficiency Virus: Implications for Clinical Practice and Management Challenges in the African Setting. Seminars in Pediatric Neurology 21:1, pages 3-11.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.