Advanced search
Publication Cover
International Review of Psychiatry Volume 18, 2006 - Issue 2: Lipids
Submit an article Journal homepage
380
Views
60
CrossRef citations to date
0
Altmetric
Original

Bioactive lipids in schizophrenia

Gregor E. Berger MD FMH Psych (CH) ORYGEN Youth Health and ORYGEN Research Centre, Department of Psychiatry, University of Melbourne, AustraliaCorrespondence[email protected]
,
Stefan Smesny Department of Psychiatry, University of Jena, Jena, Germany
&
G. Paul Amminger Department of Child and Adolescent Psychiatry, Medical University of Vienna, Austria
Pages 85-98 | Published online: 11 Jul 2009

Citations (60)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Andrea Schmitt, Daniel Martins-de-Souza, Schahram Akbarian, Juliana S. Cassoli, Hannelore Ehrenreich, Andre Fischer, Alfred Fonteh, Wagner F. Gattaz, Michael Gawlik, Manfred Gerlach, Edna Grünblatt, Tobias Halene, Alkomiet Hasan, Kenij Hashimoto, Yong-Ku Kim, Sophie-Kathrin Kirchner, Johannes Kornhuber, Theo F.J. Kraus, Berend Malchow, Juliana M. Nascimento, Moritz Rossner, Markus Schwarz, Johann Steiner, Leda Talib, Florence Thibaut, Peter Riederer & Peter Falkai. (2017) Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms. The World Journal of Biological Psychiatry 18:5, pages 330-356.
Read now
Molly K Larson, Elaine F Walker & Michael T Compton. (2010) Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disorders. Expert Review of Neurotherapeutics 10:8, pages 1347-1359.
Read now
Cai Song & Shannon Zhao. (2007) Omega-3 fatty acid eicosapentaenoic acid. A new treatment for psychiatric and neurodegenerative diseases: a review of clinical investigations. Expert Opinion on Investigational Drugs 16:10, pages 1627-1638.
Read now
Rao Muralikrishna Adibhatla & James F Hatcher. (2007) Role Of Lipids In Brain Injury And Diseases. Future Lipidology 2:4, pages 403-422.
Read now

Articles from other publishers (56)

Michaela Schmidt, Andrea Carlo Rossetti, Christiane Brandwein, Marco Andrea Riva, Peter Gass, Peter Elsner, Jana Hesse-Macabata, Uta-Christina Hipler, Stefan Smesny & Berko Milleit. (2022) Brain Derived Neurotrophic Factor Deficiency is Associated with Cognitive Impairment and Elevated Phospholipase A2 Activity in Plasma of Mice. Neuroscience 480, pages 167-177.
Crossref
Patrick D. McGorry & Cristina Mei. (2021) Clinical Staging for Youth Mental Disorders: Progress in Reforming Diagnosis and Clinical Care. Annual Review of Developmental Psychology 3:1, pages 15-39.
Crossref
Leda L. Talib, Alana C. Costa, Helena P. G. Joaquim, Cícero A. C. Pereira, Martinus T. Van de Bilt, Alexandre A. Loch & Wagner F. Gattaz. (2021) Increased PLA2 activity in individuals at ultra-high risk for psychosis. European Archives of Psychiatry and Clinical Neuroscience 271:8, pages 1593-1599.
Crossref
Liam Sharp & Grace Brannigan. (2021) Spontaneous lipid binding to the nicotinic acetylcholine receptor in a native membrane. The Journal of Chemical Physics 154:18.
Crossref
Rachmat Hidayat, Patricia Wulandari, Carla Raymondalexas Marchira & Budi Pratiti. (2021) Efficacof Cinnamon Extract (Cinnamomum burmannii) as Supplementation in Lir-psychotic-induced Rats through Oxidative Stress Regulation in Neuronal Cells. Open Access Macedonian Journal of Medical Sciences 9:A, pages 177-182.
Crossref
Ayedh Alqarni, Todd W. Mitchell, Patrick D. McGorry, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R. Schäfer, Maximus Berger, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y.H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Andrew Thompson, Alison Ruth Yung, G. Paul Amminger & Barbara J. Meyer. (2020) Comparison of erythrocyte omega-3 index, fatty acids and molecular phospholipid species in people at ultra-high risk of developing psychosis and healthy people. Schizophrenia Research 226, pages 44-51.
Crossref
Chuanjun Zhuo, Weihong Hou, Hongjun Tian, Lina Wang & Ranli Li. (2020) Lipidomics of the brain, retina, and biofluids: from the biological landscape to potential clinical application in schizophrenia. Translational Psychiatry 10:1.
Crossref
Qianhui Yu, Zhisong He, Dmitry Zubkov, Shuyun Huang, Ilia Kurochkin, Xiaode Yang, Tobias Halene, Lothar Willmitzer, Patrick Giavalisco, Schahram Akbarian & Philipp Khaitovich. (2018) Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders. Molecular Psychiatry 25:11, pages 2952-2969.
Crossref
Helena P. G. Joaquim, Alana Caroline Costa, Maurício Henriques Serpa, Leda L. Talib & Wagner F. Gattaz. (2019) Reduced Annexin A3 in schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 270:4, pages 489-494.
Crossref
Monia Perugini, Carmine Merola, Michele Amorena, Michele D'Angelo, Annamaria Cimini & Elisabetta Benedetti. (2019) Sublethal exposure to propylparaben leads to lipid metabolism impairment in zebrafish early‐life stages. Journal of Applied Toxicology 40:4, pages 493-503.
Crossref
Wen-Chen Ouyang, Gwo-Ching Sun & Mei-Chi Hsu. (2020) Omega-3 fatty acids in cause, prevention and management of violence in schizophrenia: Conceptualization and application. Aggression and Violent Behavior 50, pages 101347.
Crossref
Gregor E. Berger. 2019. Clinical Staging in Psychiatry. Clinical Staging in Psychiatry 191 203 .
Seyed Tayebati. (2018) Phospholipid and Lipid Derivatives as Potential Neuroprotective Compounds. Molecules 23:9, pages 2257.
Crossref
Arshiya Shamim, Tarique Mahmood, Farogh Ahsan, Arun Kumar & Paramdeep Bagga. (2018) Lipids: An insight into the neurodegenerative disorders. Clinical Nutrition Experimental 20, pages 1-19.
Crossref
Mai H. Philipsen, Nhu T. N. Phan, John S. Fletcher, Per Malmberg & Andrew G. Ewing. (2018) Mass Spectrometry Imaging Shows Cocaine and Methylphenidate Have Opposite Effects on Major Lipids in Drosophila Brain . ACS Chemical Neuroscience 9:6, pages 1462-1468.
Crossref
Liya Sun, Xuhan Yang, Jie Jiang, Xiaowen Hu, Ying Qing, Dandan Wang, Tianqi Yang, Chao Yang, Juan Zhang, Ping Yang, Peng Wang, Changqun Cai, Jijun Wang, Lin He & Chunling Wan. (2018) Identification of the Niacin-Blunted Subgroup of Schizophrenia Patients from Mood Disorders and Healthy Individuals in Chinese Population. Schizophrenia Bulletin 44:4, pages 896-907.
Crossref
H.J. Rogier HoendersAgna A. Bartels-VelthuisNina K. VollbehrRichard BruggemanHenderikus KnegteringJoop T.V.M. de Jong. (2018) Natural Medicines for Psychotic Disorders. Journal of Nervous & Mental Disease 206:2, pages 81-101.
Crossref
Błażej Misiak, Bartłomiej Stańczykiewicz, Łukasz Łaczmański & Dorota Frydecka. (2017) Lipid profile disturbances in antipsychotic-naive patients with first-episode non-affective psychosis: A systematic review and meta-analysis. Schizophrenia Research 190, pages 18-27.
Crossref
Miriam Schneider, Beth Levant, Martin Reichel, Erich Gulbins, Johannes Kornhuber & Christian P. Müller. (2017) Lipids in psychiatric disorders and preventive medicine. Neuroscience & Biobehavioral Reviews 76, pages 336-362.
Crossref
Erica Zamberletti, Fabiana Piscitelli, Valentina De Castro, Elisabetta Murru, Marina Gabaglio, Paola Colucci, Chiara Fanali, Pamela Prini, Tiziana Bisogno, Mauro Maccarrone, Patrizia Campolongo, Sebastiano Banni, Tiziana Rubino & Daniela Parolaro. (2017) Lifelong imbalanced LA/ALA intake impairs emotional and cognitive behavior via changes in brain endocannabinoid system. Journal of Lipid Research 58:2, pages 301-316.
Crossref
Sumit Sethi, Mirian A. F. Hayashi, Banny S. Barbosa, João G. M. Pontes, Ljubica Tasic & Elisa Brietzke. 2017. Metabolomics: From Fundamentals to Clinical Applications. Metabolomics: From Fundamentals to Clinical Applications 265 290 .
Gerwyn Morris, Ken Walder, Basant K. Puri, Michael Berk & Michael Maes. (2015) The Deleterious Effects of Oxidative and Nitrosative Stress on Palmitoylation, Membrane Lipid Rafts and Lipid-Based Cellular Signalling: New Drug Targets in Neuroimmune Disorders. Molecular Neurobiology 53:7, pages 4638-4658.
Crossref
Fulvio D’Acquisto. (2016) Editorial overview: Immunomodulation: Exploiting the circle between emotions and immunity: impact on pharmacological treatments. Current Opinion in Pharmacology 29, pages viii-xii.
Crossref
Xianlin Han. 2016. Lipidomics. Lipidomics 377 404 .
S. M. Cotton, K. M. Filia, A. Ratheesh, K. Pennell, S. Goldstone & P. D. McGorry. (2015) Early psychosis research at Orygen, The National Centre of Excellence in Youth Mental Health. Social Psychiatry and Psychiatric Epidemiology 51:1, pages 1-13.
Crossref
Ab Latif Wani, Sajad Ahmad Bhat & Anjum Ara. (2015) Omega-3 fatty acids and the treatment of depression: a review of scientific evidence. Integrative Medicine Research 4:3, pages 132-141.
Crossref
Khaled Al Awam, Ida Sibylle Haußleiter, Ed Dudley, Rossen Donev, Martin Brüne, Georg Juckel & Johannes Thome. (2014) Multiplatform metabolome and proteome profiling identifies serum metabolite and protein signatures as prospective biomarkers for schizophrenia. Journal of Neural Transmission 122:S1, pages 111-122.
Crossref
William V. Bobo, Judith L. Rapoport, Anissa Abi‐Dargham, S. Hossein Fatemi & Herbert Y. Meltzer. 2015. Psychiatry. Psychiatry 303 319 .
G P Amminger, A Mechelli, S Rice, S-W Kim, C M Klier, R K McNamara, M Berk, P D McGorry & M R Schäfer. (2015) Predictors of treatment response in young people at ultra-high risk for psychosis who received long-chain omega-3 fatty acids. Translational Psychiatry 5:1, pages e495-e495.
Crossref
Patrick McGorry, Matcheri Keshavan, Sherilyn Goldstone, Paul Amminger, Kelly Allott, Michael Berk, Suzie Lavoie, Christos Pantelis, Alison Yung, Stephen Wood & Ian Hickie. (2014) Biomarkers and clinical staging in psychiatry. World Psychiatry 13:3, pages 211-223.
Crossref
Tuulia Hyötyläinen & Matej Orešič. (2014) Systems biology strategies to study lipidomes in health and disease. Progress in Lipid Research 55, pages 43-60.
Crossref
Sarah Dassati, Andreas Waldner & Rüdiger Schweigreiter. (2014) Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain. Neurobiology of Aging 35:7, pages 1632-1642.
Crossref
S Smesny, B Milleit, U-C Hipler, C Milleit, M R Schäfer, C M Klier, M Holub, I Holzer, G E Berger, M Otto, I Nenadic, M Berk, P D McGorry, H Sauer & G P Amminger. (2013) Omega-3 fatty acid supplementation changes intracellular phospholipase A2 activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis. Molecular Psychiatry 19:3, pages 317-324.
Crossref
Stefan Smesny, Christian E. H. Schmelzer, Anke Hinder, Alexandra Köhler, Christiane Schneider, Maria Rudzok, Ulrike Schmidt, Berko Milleit, Christine Milleit, Igor Nenadic, Heinrich Sauer, Reinhard H. H. Neubert & Joachim W. Fluhr. (2013) Skin Ceramide Alterations in First-Episode Schizophrenia Indicate Abnormal Sphingolipid Metabolism. Schizophrenia Bulletin 39:4, pages 933-941.
Crossref
Julieta Ramos-Loyo, Virginia Medina-Hernández, Mirna Estarrón-Espinosa, Alejandro Canales-Aguirre, Ulises Gómez-Pinedo & Luis F. Cerdán-Sánchez. (2013) Sex differences in lipid peroxidation and fatty acid levels in recent onset schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 44, pages 154-161.
Crossref
Paul Sunday Ogunro, Benjamin Adekunle Eegunranti, Adeniran Samuel Atiba, Elizabeth Olufunke Oke & Joel Olufunminiyi Akande. (2013) Status of antioxidant defense and lipid peroxidation in schizophrenics with positive, negative and cognitive symptoms. Free Radicals and Antioxidants 3:1, pages 20-24.
Crossref
Moses O Akiibinu, Omobola A Ogundahunsi & Ebenezer O Ogunyemi. (2012) Inter-relationship of plasma markers of oxidative stress and thyroid hormones in schizophrenics. BMC Research Notes 5:1.
Crossref
G P Amminger, M R Schäfer, C M Klier, J-M Slavik, I Holzer, M Holub, S Goldstone, T J Whitford, P D McGorry & M Berk. (2011) Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seeking ultra-high-risk individuals. Molecular Psychiatry 17:12, pages 1150-1152.
Crossref
G Paul Amminger & Patrick D McGorry. (2011) Update on Omega-3 Polyunsaturated Fatty Acids in Early-Stage Psychotic Disorders. Neuropsychopharmacology 37:1, pages 309-310.
Crossref
Laure Buydens-Branchey, Marc Branchey & Joseph R. Hibbeln. (2011) Higher n−3 fatty acids are associated with more intense fenfluramine-induced ACTH and cortisol responses among cocaine-abusing men. Psychiatry Research 188:3, pages 422-427.
Crossref
Benjamin Pickard. (2011) Progress in defining the biological causes of schizophrenia. Expert Reviews in Molecular Medicine 13.
Crossref
Joachim Klosterkötter. (2011) Early detection of schizophrenia. Neurology, Psychiatry and Brain Research 17:1, pages 1-10.
Crossref
Stefan Smesny, Berko Milleit, Igor Nenadic, Christoph Preul, Daniel Kinder, Jürgen Lasch, Ingo Willhardt, Heinrich Sauer & Christian Gaser. (2010) Phospholipase A2 activity is associated with structural brain changes in schizophrenia. NeuroImage 52:4, pages 1314-1327.
Crossref
Ramadhan Oruch, Anders Lund, Ian F. Pryme & Holm Holmsen. (2010) An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?. Journal of Chemical Biology 3:2, pages 67-88.
Crossref
Christoph U. Correll, Marta Hauser, Andrea M. Auther & Barbara A. Cornblatt. (2010) Research in people with psychosis risk syndrome: a review of the current evidence and future directions. Journal of Child Psychology and Psychiatry 51:4, pages 390-431.
Crossref
Rao Muralikrishna AdibhatlaJames Franklin Hatcher. (2010) Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities. Antioxidants & Redox Signaling 12:1, pages 125-169.
Crossref
Ziqiang Guan. (2009) Discovering novel brain lipids by liquid chromatography/tandem mass spectrometry. Journal of Chromatography B 877:26, pages 2814-2821.
Crossref
P. Milev, S. Miranowski & K. O. Lim. 2009. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology 403 442 .
Gregor E Berger, Stephen J Wood, R Mark Wellard, Tina M Proffitt, Mirabel McConchie, G Paul Amminger, Graeme D Jackson, Dennis Velakoulis, Christos Pantelis & Patrick D McGorry. (2008) Ethyl-Eicosapentaenoic Acid in First-Episode Psychosis. A 1H-MRS Study. Neuropsychopharmacology 33:10, pages 2467-2473.
Crossref
Joachim Klosterkötter, Frauke Schultze-Lutter & Stephan Ruhrmann. (2008) Kraepelin and psychotic prodromal conditions. European Archives of Psychiatry and Clinical Neuroscience 258:S2, pages 74-84.
Crossref
Laure Buydens-Branchey & Marc Branchey. (2008) Long-chain n-3 polyunsaturated fatty acids decrease feelings of anger in substance abusers. Psychiatry Research 157:1-3, pages 95-104.
Crossref
Scott D. Mendelson. 2008. Metabolic Syndrome and Psychiatric Illness. Metabolic Syndrome and Psychiatric Illness 141 186 .
Rao Muralikrishna Adibhatla & J. F. Hatcher. 2008. Lipids in Health and Disease. Lipids in Health and Disease 241 268 .
Emanuel Schwarz & Sabine Bahn. 2009. Biomarkers for Psychiatric Disorders. Biomarkers for Psychiatric Disorders 75 96 .
Gregor Berger, Margaret Dell?Olio, Paul Amminger, Barbara Cornblatt, Lisa Phillips, Alison Yung, Yung Yan, Michael Berk & Patrick McGorry. (2007) Neuroprotection in emerging psychotic disorders. Early Intervention in Psychiatry 1:2, pages 114-127.
Crossref
X. Sun, D. Zhou, P. Zhang, E. G. Moczydlowski & G. G. Haddad. (2007) β-Subunit–Dependent Modulation of hSlo BK Current by Arachidonic Acid . Journal of Neurophysiology 97:1, pages 62-69.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.