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Journal of Dermatological Treatment Volume 33, 2022 - Issue 3
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Articles

Baricitinib improves symptoms in patients with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids: patient-reported outcomes from two randomized monotherapy phase III trials

K. Reicha Translational Research in Inflammatory Skin Diseases, Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, Skinflammation Center, Hamburg and Dermatologikum Berlin, Berlin, GermanyView further author information
,
A. M. DeLozierb Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
F. P. Nunesb Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
J. P. Thyssenc Department of Dermatology and Allergy, Herlev and Gentofte Hospital and University of Copenhagen, Copenhagen, DenmarkView further author information
,
L. F. Eichenfieldd Departments of Dermatology and Pediatrics, University of California, San Diego and Rady Children’s Hospital, San Diego, CA, USAView further author information
,
A. Wollenberge Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, GermanyView further author information
,
J. A. Ross Terresb Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
S. D. Wattsb Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
Y.-F. Chenb Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
E. L. Simpsonf Department of Dermatology, Oregon Health and Science University, Portland, OR, USAView further author information
&
J. I. Silverbergg Department of Dermatology, George Washington University School of Medicine, Washington, DC, USACorrespondence[email protected]
View further author information
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Pages 1521-1530 | Received 17 Sep 2020, Accepted 15 Oct 2020, Published online: 22 Nov 2020

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Read on this site (3)

Sarah G. Bridgeman, Anna K. Martino & Lindsay C. Strowd. (2023) Evaluating the safety and efficacy of baricitinib for the treatment of moderate-to-severe atopic dermatitis. Expert Opinion on Pharmacotherapy 0:0, pages 1-7.
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Katherine A Kelly, Patrick O Perche & Steven R Feldman. (2022) Therapeutic Potential of Tralokinumab in the Treatment of Atopic Dermatitis: A Review on the Emerging Clinical Data. Clinical, Cosmetic and Investigational Dermatology 15, pages 1037-1043.
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Svenja Müller, Thomas Bieber & Sonja Ständer. (2022) Therapeutic potential of biologics in prurigo nodularis. Expert Opinion on Biological Therapy 22:1, pages 47-58.
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Articles from other publishers (20)

Jacob P. Thyssen, Thomas Bieber, C. Elise Kleyn, Audrey Nosbaum, Susanne Grond, Helmut Petto, Elisabeth Riedl & Andreas Wollenberg. (2023) Baricitinib provides rapid and sustained improvements in absolute EASI and SCORAD outcomes in adults with moderate-to-severe atopic dermatitis. Journal of Dermatological Treatment 34:1.
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Pei-Yun Shih, Chia-Jung Li & Su-Boon Yong. (2023) Emerging trends in clinical research on Janus kinase inhibitors for atopic dermatitis treatment. International Immunopharmacology 124, pages 111029.
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Raquel Leao Orfali, Daniel Lorenzini, Aline Bressan, Anber Ancel Tanaka, Ana Maria Mósca de Cerqueira, André da Silva Hirayama, Andréa Machado Coelho Ramos, Carolina Contin Proença, Claudia Marcia de Resende Silva, Cristina Marta Maria Laczynski, Francisca Regina Carneiro, Gleison Duarte, Gunter Hans Filho, Heitor de Sá Gonçalves, Ligia Pessoa de Melo, Luna Azulay-Abulafia, Magda Blessmann Weber, Maria Cecília Rivitti-Machado, Mariana Colombini Zaniboni, Marília Ogawa, Mario Cezar Pires, Mayra Ianhez, Paulo Antonio Oldani Felix, Renan Bonamigo, Roberto Takaoka, Rosana Lazzarini, Silmara Cestari, Silvia Assumpção Soutto Mayor, Tania Cestari, Zilda Najjar Prado de Oliveira, Phyllis I. Spuls, Louise A.A. Gerbens & Valeria Aoki. (2023) Consensus on the therapeutic management of atopic dermatitis ‒ Brazilian Society of Dermatology: an update on phototherapy and systemic therapy using e-Delphi technique. Anais Brasileiros de Dermatologia 98:6, pages 814-836.
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Flaminia Antonelli, Dalma Malvaso, Giacomo Caldarola, Clara De Simone, Ketty Peris & Andrea Chiricozzi. (2023) Infectious adverse events in patients with atopic dermatitis treated with baricitinib. Immunotherapy.
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Hélio Amante Miot, Paulo Ricardo Criado, Caio César Silva de Castro, Mayra Ianhez, Carolina Talhari & Paulo Müller Ramos. (2023) JAK-STAT pathway inhibitors in dermatology. Anais Brasileiros de Dermatologia 98:5, pages 656-677.
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Andreas WollenbergLeon KircikEric SimpsonDennis BrinkerNorito KatohMaria Jose RuedaMaher IssaFan YangMeghan FeelyAndrew Alexis. (2023) Pooled Analysis of Baricitinib Tolerability in Patients With Atopic Dermatitis in Relation to Acne, Headache, and Gastrointestinal Events From 8 Clinical Trials. Dermatitis® 34:4, pages 308-314.
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Laura Maintz, Thomas Welchowski, Nadine Herrmann, Juliette Brauer, Claudia Traidl‐Hoffmann, Regina Havenith, Svenja Müller, Claudio Rhyner, Anita Dreher, Matthias Schmid & Thomas Bieber. (2023) IL‐13, periostin and dipeptidyl‐peptidase‐4 reveal endotype‐phenotype associations in atopic dermatitis. Allergy 78:6, pages 1554-1569.
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Anna M Trier & Brian S Kim. (2023) Insights into atopic dermatitis pathogenesis lead to newly approved systemic therapies. British Journal of Dermatology 188:6, pages 698-708.
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Yael Renert-Yuval, Joel Correa da Rosa, Sandra Garcet, Ana B. Pavel, Jennifer Bares, Margot Chima, Jason E. Hawkes, Patricia Gilleaudeau, Mary Sullivan-Whalen, Giselle K. Singer, James G. Krueger & Emma Guttman-Yassky. (2022) Analysis of alopecia areata surveys suggests a threshold for improved patient-reported outcomes. British Journal of Dermatology 187:4, pages 539-547.
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T. Bieber, A.S. Paller, K. Kabashima, M. Feely, M.J. Rueda, J.A. Ross Terres & A. Wollenberg. (2022) Atopic dermatitis: pathomechanisms and lessons learned from novel systemic therapeutic options. Journal of the European Academy of Dermatology and Venereology 36:9, pages 1432-1449.
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David Rosmarin, Scott Fretzin, Lindsay Strowd, Marta Casillas, Amy M. DeLozier, Zach Dawson, Sherry Chen, Na Lu & Jacob P. Thyssen. (2022) Rapid Improvement in Skin Pain Severity and Its Impact on Quality of Life in Adult Patients With Moderate-to-Severe Atopic Dermatitis From a Double-Blind, Placebo-Controlled Baricitinib Phase 3 Study. Journal of Cutaneous Medicine and Surgery 26:4, pages 377-385.
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Svenja Müller, Felix Witte & Sonja Ständer. (2022) Pruritus bei atopischer Dermatitis – vergleichende Bewertung neuer TherapieansätzePruritus in atopic dermatitis—comparative evaluation of novel treatment approaches. Die Dermatologie 73:7, pages 538-549.
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Felix Lauffer & Tilo Biedermann. (2022) Einschätzungen zur Therapie der moderaten bis schweren atopischen Dermatitis mit JanuskinaseinhibitorenJanus kinase inhibitors for the treatment of atopic dermatitis—evaluation of current data and practical experience. Die Dermatologie 73:7, pages 520-528.
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Sheridan M. Hoy. (2022) Baricitinib: A Review in Moderate to Severe Atopic Dermatitis. American Journal of Clinical Dermatology 23:3, pages 409-420.
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Danielle Rogner, Tilo Biedermann & Felix Lauffer. (2022) Treatment of Atopic Dermatitis with Baricitinib: First Real-life Experience. Acta Dermato-Venereologica 102, pages adv00677.
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Giulia Radi, Oriana Simonetti, Giulio Rizzetto, Federico Diotallevi, Elisa Molinelli & Annamaria Offidani. (2021) Baricitinib: The First Jak Inhibitor Approved in Europe for the Treatment of Moderate to Severe Atopic Dermatitis in Adult Patients. Healthcare 9:11, pages 1575.
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Kazumasa Kamei, Tomohiro Hirose, Noritoshi Yoshii & Akio Tanaka. (2021) Burden of illness, medication adherence, and unmet medical needs in Japanese patients with atopic dermatitis: A retrospective analysis of a cross‐sectional questionnaire survey. The Journal of Dermatology 48:10, pages 1491-1498.
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Jonathan I. Silverberg, Jacob P. Thyssen, Eric L. Simpson, Gil Yosipovitch, Sonja Ständer, Hernan Valdez, Ricardo Rojo, Pinaki Biswas, Daniela E. Myers, Claire Feeney & Marco DiBonaventura. (2021) Impact of Oral Abrocitinib Monotherapy on Patient-Reported Symptoms and Quality of Life in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis: A Pooled Analysis of Patient-Reported Outcomes. American Journal of Clinical Dermatology 22:4, pages 541-554.
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Felix Lauffer & Tilo Biedermann. (2021) Atopisches Ekzem: Störfeuer für eine Dreiecksbeziehung. Deutsches Ärzteblatt Online.
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Yihong He, Suyun Ji & Qinghong Yu. (2021) Effectiveness of baricitinib in prurigo‐type atopic dermatitis: A case report. Dermatologic Therapy 34:2.
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