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International Journal of Radiation Biology Volume 76, 2000 - Issue 11
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Research Article

Radiation effects in spheroids of cells exposed to alpha emitters

D. E. Charlton
Pages 1555-1564 | Published online: 03 Jul 2009

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Roger W. Howell, Didier Rajon & Wesley E. Bolch. (2012) Monte Carlo simulation of irradiation and killing in three-dimensional cell populations with lognormal cellular uptake of radioactivity. International Journal of Radiation Biology 88:1-2, pages 115-122.
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Articles from other publishers (17)

Sumudu Katugampola, Jianchao Wang, Aprameya Prasad, Stavroula Sofou & Roger W. Howell. (2022) Predicting response of micrometastases with MIRDcell V3: proof of principle with 225Ac-DOTA encapsulating liposomes that produce different activity distributions in tumor spheroids. European Journal of Nuclear Medicine and Molecular Imaging 49:12, pages 3989-3999.
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Sumudu Katugampola, Jianchao Wang, Alex Rosen & Roger W. Howell. (2022) MIRD Pamphlet No. 27: MIRDcell V3, a Revised Software Tool for Multicellular Dosimetry and Bioeffect Modeling. Journal of Nuclear Medicine 63:9, pages 1441-1449.
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Francisco D C Guerra Liberal, Stephen J McMahon & Kevin M Prise. (2021) TOPAS a tool to evaluate the impact of cell geometry and radionuclide on alpha particle therapy. Biomedical Physics & Engineering Express 7:3, pages 035008.
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A. Bertolet, M. A. Cortés-Giraldo & A. Carabe-Fernandeza. (2020) An Analytical Microdosimetric Model for Radioimmunotherapeutic Alpha Emitters. Radiation Research 194:4.
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Francisco D.C. Guerra LiberalJoe M. O'SullivanStephen J. McMahonKevin M. Prise. (2020) Targeted Alpha Therapy: Current Clinical Applications. Cancer Biotherapy and Radiopharmaceuticals 35:6, pages 404-417.
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J. J. M. Kouwenberg, H. T. Wolterbeek, A. G. Denkova & A. J. J. Bos. (2018) Fluorescent nuclear track detectors for alpha radiation microdosimetry. Radiation Oncology 13:1.
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Christopher M. Poole, Anders Ahnesjö & Shirin A. Enger. (2015) Determination of subcellular compartment sizes for estimating dose variations in radiotherapy. Radiation Protection Dosimetry 166:1-4, pages 361-364.
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Behrooz Vaziri, Han Wu, Atam P. Dhawan, Peicheng Du & Roger W. Howell. (2014) MIRD Pamphlet No. 25: MIRDcell V2.0 Software Tool for Dosimetric Analysis of Biologic Response of Multicellular Populations. Journal of Nuclear Medicine 55:9, pages 1557-1564.
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Ernesto Amato, Antonio Italiano & Sergio Baldari. (2013) Absorbed fractions for alpha particles in ellipsoidal volumes. Physics in Medicine and Biology 58:16, pages 5449-5459.
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Didier Rajon, Wesley E. Bolch & Roger W. Howell. (2012) Survival of tumor and normal cells upon targeting with electron-emitting radionuclides. Medical Physics 40:1, pages 014101.
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Didier Rajon, Wesley E. Bolch & Roger W. Howell. (2011) Lognormal Distribution of Cellular Uptake of Radioactivity: Monte Carlo Simulation of Irradiation and Cell Killing in 3-Dimensional Populations in Carbon Scaffolds. Journal of Nuclear Medicine 52:6, pages 926-933.
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George Sgouros, John C. Roeske, Michael R. McDevitt, Stig Palm, Barry J. Allen, Darrell R. Fisher, A. Bertrand Brill, Hong Song, Roger W. Howell & Gamal Akabani. (2010) MIRD Pamphlet No. 22 (Abridged): Radiobiology and Dosimetry of α-Particle Emitters for Targeted Radionuclide Therapy. Journal of Nuclear Medicine 51:2, pages 311-328.
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John C. Roeske, Bulent Aydogan, Manuel Bardies & John L. Humm. (2008) Small-Scale Dosimetry: Challenges and Future Directions. Seminars in Nuclear Medicine 38:5, pages 367-383.
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Nicolas Chouin, Abdalkader Bitar, Albert Lisbona, Michel Chérel, François Davodeau, Jacques Barbet & Manuel Bardiès. (2007) Implementation of a Microdosimetric Model for Radioimmunotherapeutic Alpha Emitters. Cancer Biotherapy and Radiopharmaceuticals 22:3, pages 387-392.
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John C Roeske & Mark Hoggarth. (2007) Alpha-particle Monte Carlo simulation for microdosimetric calculations using a commercial spreadsheet. Physics in Medicine and Biology 52:7, pages 1909-1922.
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Olivier Couturier, Stéphane Supiot, Marie Degraef-Mougin, Alain Faivre-Chauvet, Thomas Carlier, Jean-François Chatal, François Davodeau & Michel Cherel. (2005) Cancer radioimmunotherapy with alpha-emitting nuclides. European Journal of Nuclear Medicine and Molecular Imaging 32:5, pages 601-614.
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M. Boyd, S. C. Mairs, K. Stevenson, A. Livingstone, A. M. Clark, S. C. Ross & R. J. Mairs. (2002) Transfectant mosaic spheroids: a new model for evaluation of tumour cell killing in targeted radiotherapy and experimental gene therapy. The Journal of Gene Medicine 4:5, pages 567-576.
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