Advanced search
Publication Cover
International Journal of Radiation Biology Volume 79, 2003 - Issue 8
Submit an article Journal homepage
93
Views
39
CrossRef citations to date
0
Altmetric
DNA damage: mutation, chromatid breaks, strand breaks

Modelling study on the protective role of OH radical scavengers and DNA higher‐order structures in induction of single‐ and double‐strand break by gamma‐radiation

A. Valota Università degli Studi di Milano, Dipartimento di Fisica, via Celoria 16, I‐20133 Milan, ItalyCorrespondence[email protected]
,
F. Ballarini Università degli Studi di Pavia, Dipartimento di Fisica Nucleare e Teorica, and INFN—Sezione di Pavia, via Bassi 6, I‐27100 Pavia, Italy
,
W. Friedland GSF‐Institute of Radiation Protection, Ingolstädter Landstr. 1, D‐85758 Neuherberg (Munich), Germany
,
P. Jacob Università degli Studi di Milano, Dipartimento di Fisica, via Celoria 16, I‐20133 Milan, Italy
,
A. Ottolenghi Università degli Studi di Pavia, Dipartimento di Fisica Nucleare e Teorica, and INFN—Sezione di Pavia, via Bassi 6, I‐27100 Pavia, Italy
&
H. G. Paretzke GSF‐Institute of Radiation Protection, Ingolstädter Landstr. 1, D‐85758 Neuherberg (Munich), Germany
Pages 643-653 | Received 18 Nov 2002, Accepted 30 May 2003, Published online: 03 Jul 2009

Citations (39)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Daniele Alloni, Alessandro Campa, Werner Friedland, Luca Mariotti & Andrea Ottolenghi. (2012) Track structure, radiation quality and initial radiobiological events: Considerations based on the PARTRAC code experience. International Journal of Radiation Biology 88:1-2, pages 77-86.
Read now

Articles from other publishers (38)

Jingyi Bian, Juan Duran, Wook-Geun Shin, Jose Ramos-Méndez, Jack C Sankey, Lilian Childress, Jan Seuntjens & Shirin A Enger. (2023) GEANT4-DNA simulation of temperature-dependent and pH-dependent yields of chemical radiolytic species. Physics in Medicine & Biology 68:12, pages 124002.
Crossref
Marc Benjamin Hahn. (2023) Accessing radiation damage to biomolecules on the nanoscale by particle-scattering simulations. Journal of Physics Communications 7:4, pages 042001.
Crossref
Flore Chappuis, Veljko Grilj, Hoang Ngoc Tran, Sara A. Zein, François Bochud, Claude Bailat, Sébastien Incerti & Laurent Desorgher. (2023) Modeling of scavenging systems in water radiolysis with Geant4-DNA. Physica Medica 108, pages 102549.
Crossref
Alaina Bui, Hamed Bekerat, Lilian Childress, Jack Sankey, Jan Seuntjens & Shirin A. Enger. (2023) Effects of incoming particle energy and cluster size on the G-value of hydrated electrons. Physica Medica 107, pages 102540.
Crossref
Katsuhiko Minami, Shiori Iida & Kazuhiro Maeshima. 2022. DNA Damage and Double Strand Breaks - Part A. DNA Damage and Double Strand Breaks - Part A 29 51 .
Jing Tang, Qinfeng Xiao, Zhiguo Gui, Baosheng Li & Pengcheng Zhang. (2020) Simulation of Proton-Induced DNA Damage Patterns Using an Improved Clustering Algorithm. Radiation Research 194:4.
Crossref
Kamila Sofińska, Natalia Wilkosz, Marek Szymoński & Ewelina Lipiec. (2020) Molecular Spectroscopic Markers of DNA Damage. Molecules 25:3, pages 561.
Crossref
Jelena Tamuliene, Liudmila Romanova, Vasyl Vukstich, Alexander Papp, Laura Baliulyte & Alexander Snegursky. (2019) The impact of low-energy ionizing radiation on glutamine. International Journal of Mass Spectrometry 444, pages 116185.
Crossref
Jelena Tamulienė, Liudmila Romanova, Vasyl Vukstich, Alexander Papp, Laura Baliulytė & Alexander Snegursky. (2018) On the influence of low-energy ionizing radiation on the amino acid molecule: Valine case. Lithuanian Journal of Physics 58:2.
Crossref
Igor Shuryak, Vera Y. Matrosova, Elena K. Gaidamakova, Rok Tkavc, Olga Grichenko, Polina Klimenkova, Robert P. Volpe & Michael J. Daly. (2017) Microbial cells can cooperate to resist high-level chronic ionizing radiation. PLOS ONE 12:12, pages e0189261.
Crossref
Gabriel Famulari, Piotr Pater & Shirin A Enger. (2017) Microdosimetry calculations for monoenergetic electrons using Geant4-DNA combined with a weighted track sampling algorithm. Physics in Medicine & Biology 62:13, pages 5495-5508.
Crossref
Vincent J. Cannistraro, Santhi Pondugula, Qian Song & John-Stephen Taylor. (2015) Rapid Deamination of Cyclobutane Pyrimidine Dimer Photoproducts at TCG Sites in a Translationally and Rotationally Positioned Nucleosome in Vivo. Journal of Biological Chemistry 290:44, pages 26597-26609.
Crossref
Marjan Tajik, Amir S.H. Rozatian & Farid Semsarha. (2015) Simulation of ultrasoft X-rays induced DNA damage using the Geant4 Monte Carlo toolkit. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 342, pages 258-265.
Crossref
Christophe Lavelle & Nicolas Foray. (2014) Chromatin structure and radiation-induced DNA damage: From structural biology to radiobiology. The International Journal of Biochemistry & Cell Biology 49, pages 84-97.
Crossref
D. Alloni, L.G. Mariotti & A. Ottolenghi. 2014. Comprehensive Biomedical Physics. Comprehensive Biomedical Physics 1 22 .
Hideaki Takata, Tomo Hanafusa, Toshiaki Mori, Mari Shimura, Yutaka Iida, Kenichi Ishikawa, Kenichi Yoshikawa, Yuko Yoshikawa & Kazuhiro Maeshima. (2013) Chromatin Compaction Protects Genomic DNA from Radiation Damage. PLoS ONE 8:10, pages e75622.
Crossref
P Lazarakis, M U Bug, E Gargioni, S Guatelli, H Rabus & A B Rosenfeld. (2012) Comparison of nanodosimetric parameters of track structure calculated by the Monte Carlo codes Geant4-DNA and PTra. Physics in Medicine and Biology 57:5, pages 1231-1250.
Crossref
Anita Krisko, Magali LeroyMiroslav Radman & Matthew Meselson. (2012) Extreme anti-oxidant protection against ionizing radiation in bdelloid rotifers. Proceedings of the National Academy of Sciences 109:7, pages 2354-2357.
Crossref
Werner Friedland, Michael Dingfelder, Pavel Kundrát & Peter Jacob. (2011) Track structures, DNA targets and radiation effects in the biophysical Monte Carlo simulation code PARTRAC. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 711:1-2, pages 28-40.
Crossref
Alla Synytsya, Andriy Synytsya, Petr Alexa, Richard Wagner, Marie Davídková & Karel Volka. (2011) Raman spectroscopic study on sodium hyaluronate: an effect of proton and γ irradiation. Journal of Raman Spectroscopy 42:3, pages 544-550.
Crossref
D. Alloni, A. Campa, M. Belli, G. Esposito, L. Mariotti, M. Liotta, W. Friedland, H. Paretzke & A. Ottolenghi. (2010) Monte Carlo evaluation of DNA fragmentation spectra induced by different radiation qualities. Radiation Protection Dosimetry 143:2-4, pages 226-231.
Crossref
S. Denifl, H. D. Flosadóttir, A. Edtbauer, O. Ingólfsson, T. D. Märk & P. Scheier. (2010) A detailed study on the decomposition pathways of the amino acid valine upon dissociative electron attachment. The European Physical Journal D 60:1, pages 37-44.
Crossref
Maximilian Stephan Kreipl, Werner Friedland & Herwig G. Paretzke. (2009) Interaction of ion tracks in spatial and temporal proximity. Radiation and Environmental Biophysics 48:4, pages 349-359.
Crossref
Maximilian S. Kreipl, Werner Friedland & Herwig G. Paretzke. (2008) Time- and space-resolved Monte Carlo study of water radiolysis for photon, electron and ion irradiation. Radiation and Environmental Biophysics 48:1, pages 11-20.
Crossref
S. Denifl, I. Mähr, F. Ferreira da Silva, F. Zappa, T. D. Märk & P. Scheier. (2008) Electron impact ionization studies with the amino acid valine in the gas phase and (hydrated) in helium droplets. The European Physical Journal D 51:1, pages 73-79.
Crossref
Sangyong Lim, Jinwoo Jung, Minjeong Kim, Sangryeol Ryu & Dongho Kim. (2008) Effect of ionizing radiation on the quantitative detection of Salmonella using real-time PCR. Radiation Physics and Chemistry 77:9, pages 1112-1117.
Crossref
Thilo Elsässer, Stephan Brons, Katarzyna Psonka, Michael Scholz, Ewa Gudowska-Nowak & Gisela Taucher-Scholz. (2008) Biophysical Modeling of Fragment Length Distributions of DNA Plasmids after X and Heavy-Ion Irradiation Analyzed by Atomic Force Microscopy. Radiation Research 169:6, pages 649-659.
Crossref
Werner Friedland, Herwig G. Paretzke, Francesca Ballarini, Andrea Ottolenghi, Gregor Kreth & Christoph Cremer. (2008) First steps towards systems radiation biology studies concerned with DNA and chromosome structure within living cells. Radiation and Environmental Biophysics 47:1, pages 49-61.
Crossref
Alla Synytsya, Petr Alexa, Jorrit de Boer, Markus Loewe, Martin Moosburger, Michael Würkner & Karel Volka. (2007) Raman spectroscopic study of calf thymus DNA: an effect of proton- and γ-irradiation. Journal of Raman Spectroscopy 38:11, pages 1406-1415.
Crossref
Urmila Tawar, Sandhya Bansal, Shiteshu Shrimal, Manish Singh & Vibha Tandon. (2007) Nuclear condensation and free radical scavenging: a dual mechanism of bisbenzimidazoles to modulate radiation damage to DNA. Molecular and Cellular Biochemistry 305:1-2, pages 221-233.
Crossref
Marie-Eve Dextraze, J. Richard Wagner & Darel J. Hunting. (2007) 5-Bromodeoxyuridine Radiosensitization:  Conformation-Dependent DNA Damage. Biochemistry 46:31, pages 9089-9097.
Crossref
Clemens von Sonntag. 2007. 5 20 .
Werner Friedland, Peter Jacob, Herwig G. Paretzke, Andrea Ottolenghi, Francesca Ballarini & Marco Liotta. (2006) Simulation of light ion induced DNA damage patterns. Radiation Protection Dosimetry 122:1-4, pages 116-120.
Crossref
D. Alloni, F. Ballarini, W. Friedland, M. Liotta, S. Molinelli, A. Ottolenghi, H. G. Paretzke & M. Rossetti. (2006) Role of DNA/chromatin organisation and scavenging capacity in USX- and proton- induced DNA damage. Radiation Protection Dosimetry 122:1-4, pages 141-146.
Crossref
Clemens von Sonntag. 2006. Free-Radical-Induced DNA Damage and Its Repair. Free-Radical-Induced DNA Damage and Its Repair 195 210 .
Tung-Kwang Lee, Roberta M. Johnke, Ron R. Allison, Kevin F. O'Brien & Larry J. DobbsJrJr. (2005) Radioprotective potential of ginseng. Mutagenesis 20:4, pages 237-243.
Crossref
Werner Friedland, Michael Dingfelder, Peter Jacob & Herwig G. Paretzke. (2005) Calculated DNA double-strand break and fragmentation yields after irradiation with He ions. Radiation Physics and Chemistry 72:2-3, pages 279-286.
Crossref
L. Pichl, M. Kimura, Yan Li & R.J. Buenker. (2004) Branching ratios for secondary processes of water ions induced by proton beams in radiation therapy of cancer. IEEE Transactions on Nuclear Science 51:4, pages 1407-1411.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.