104
Views
37
CrossRef citations to date
0
Altmetric
Article

Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion‐associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro

, &
Pages 721-731 | Received 21 Dec 2002, Accepted 30 Jul 2003, Published online: 03 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Pablo A. Mendoza, Patricio Silva, Jorge Díaz, Cecilia Arriagada, Jimena Canales, Oscar Cerda & Vicente A. Torres. (2018) Calpain2 mediates Rab5-driven focal adhesion disassembly and cell migration. Cell Adhesion & Migration 12:3, pages 185-194.
Read now
Stephanie Hehlgans, Inga Lange, Iris Eke, Bernd Kammerer & Nils Cordes. (2011) Human head and neck squamous cell carcinoma cell lines are differentially radiosensitised by the honeybee product Propolis. International Journal of Radiation Biology 87:3, pages 243-253.
Read now
Nikolaos A Chatzizacharias, Gregory P Kouraklis & Stamatios E Theocharis. (2007) Focal adhesion kinase: a promising target for anticancer therapy. Expert Opinion on Therapeutic Targets 11:10, pages 1315-1328.
Read now
Stephanie Hehlgans, Iris Eke & Nils Cordes. (2007) An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading. International Journal of Radiation Biology 83:11-12, pages 769-779.
Read now
Divya Khaitan & B S Dwarakanath. (2006) Multicellular spheroids as an in vitro model in experimental oncology: applications in translational medicine. Expert Opinion on Drug Discovery 1:7, pages 663-675.
Read now
Francesco Marchetti, Matthew A. Coleman, Irene M. Jones & Andrew J. Wyrobek. (2006) Candidate protein biodosimeters of human exposure to ionizing radiation. International Journal of Radiation Biology 82:9, pages 605-639.
Read now

Articles from other publishers (31)

Jingduo Li, Xiupeng Zhang, Zaiyu Hou, Siqi Cai, Yingxue Guo, Limei Sun, Ailin Li, Qingchang Li, Enhua Wang & Yuan Miao. (2022) P130cas-FAK interaction is essential for YAP-mediated radioresistance of non-small cell lung cancer. Cell Death & Disease 13:9.
Crossref
Yumeng Zhang, Shu Liu, Shu Zhou, Dandan Yu, Junjie Gu, Qin Qin, Yu Cheng & Xinchen Sun. (2021) Focal adhesion kinase: Insight into its roles and therapeutic potential in oesophageal cancer. Cancer Letters 496, pages 93-103.
Crossref
Valeria Panzetta, Giuseppe La Verde, Mariagabriella Pugliese, Cecilia Arrichiello, Paolo Muto, Marco La Commara, Vittoria D'Avino, Paolo A. Netti & Sabato Fusco. (2020) Investigation of Biophysical Migration Parameters for Normal Tissue and Metastatic Cancer Cells After Radiotherapy Treatment. Frontiers in Physics 8.
Crossref
Jing Hou, Leilei Li, Haizhen Zhu, Huan Chen, Na Wei, Min Dai, Qing Ni & Xiaomao Guo. (2019) Association between breast cancer cell migration and radiosensitivity in�vitro. Oncology Letters.
Crossref
Frank Aboubakar Nana, Marie Vanderputten & Sebahat Ocak. (2019) Role of Focal Adhesion Kinase in Small-Cell Lung Cancer and Its Potential as a Therapeutic Target. Cancers 11:11, pages 1683.
Crossref
Jun-Jun Li, Wen-Zhi Tu, Xu-Ming Chen, Hou-Yu Ying, Ying Chen, Yu-Long Ge, Jing Wang, Yi Xu, Ting-Feng Chen, Xiao-Wei Zhang, Jin-Jun Ye & Yong Liu. (2018) FAK alleviates radiation-induced rectal injury by decreasing apoptosis. Toxicology and Applied Pharmacology 360, pages 131-140.
Crossref
Qiliang Peng, Kaisu Lin, Yi Shen, Ping Zhou, Shaonan Fan, Yuntian Shen & Yaqun Zhu. (2018) Identification of potential genes and pathways for response prediction of neoadjuvant chemoradiotherapy in patients with rectal cancer by systemic biological analysis. Oncology Letters.
Crossref
Hitendra S. Solanki, Remya Raja, Alex Zhavoronkov, Ivan V. Ozerov, Artem V. Artemov, Jayshree Advani, Aneesha Radhakrishnan, Niraj Babu, Vinuth N. Puttamallesh, Nazia Syed, Vishalakshi Nanjappa, Tejaswini Subbannayya, Nandini A. Sahasrabuddhe, Arun H. Patil, T.S. Keshava Prasad, Daria Gaykalova, Xiaofei Chang, Rachana Sathyendran, Premendu Prakash Mathur, Annapoorni Rangarajan, David Sidransky, Akhilesh Pandey, Evgeny Izumchenko, Harsha Gowda & Aditi Chatterjee. (2018) Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor. Oncoscience 5:1-2, pages 21-38.
Crossref
E.J. Tocce, J.Z. Gasiorowski, A.J. Youssef, R. Garcia, S.J. Liliensiek, M.J. Wilson, B. Yanez-Soto, C.J. Murphy & P.F. Nealey. 2017. Comprehensive Biomaterials II. Comprehensive Biomaterials II 404 429 .
Bu-Yeo Kim, Hee Jin, Yoon-Jin Lee, Ga-Young Kang, Jaeho Cho & Yun-Sil Lee. (2016) Focal exposure of limited lung volumes to high-dose irradiation down-regulated organ development-related functions and up-regulated the immune response in mouse pulmonary tissues. BMC Genetics 17:1.
Crossref
Chongwen Gong, Runxia Gu, Honglin Jin, Yao Sun, Zhenyu Li, Jing Chen & Gang Wu. (2015) Lysyl oxidase mediates hypoxia-induced radioresistance in non-small cell lung cancer A549 cells. Experimental Biology and Medicine 241:4, pages 387-395.
Crossref
Jesus Izaguirre-Carbonell, Hirofumi Kawakubo, Hiroshi Murata, Atsushi Tanabe, Toshifumi Takeuchi, Tomoe Kusayanagi, Senko Tsukuda, Takeshi Hirakawa, Kazuki Iwabata, Yoshihiro Kanai, Keisuke Ohta, Masahiko Miura, Kengo Sakaguchi, Sachihiro Matsunaga, Hiroeki Sahara, Shinji Kamisuki & Fumio Sugawara. (2015) Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity. Scientific Reports 5:1.
Crossref
Kathryn E. Williams, Nigel J. Bundred, Göran Landberg, Robert B. Clarke & Gillian Farnie. (2015) Focal Adhesion Kinase and Wnt Signaling Regulate Human Ductal Carcinoma In Situ Stem Cell Activity and Response to Radiotherapy. Stem Cells 33:2, pages 327-341.
Crossref
Jordan J. Toutounchian, Jena J. Steinle, Patrudu S. Makena, Christopher M. Waters, Matthew W. Wilson, Barrett G. Haik, Duane D. Miller & Charles R. Yates. (2014) Modulation of Radiation Injury Response in Retinal Endothelial Cells by Quinic Acid Derivative KZ-41 Involves p38 MAPK. PLoS ONE 9:6, pages e100210.
Crossref
Iris Eke, Ellen Dickreuter & Nils Cordes. (2012) Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by β1 integrin inhibition. Radiotherapy and Oncology 104:2, pages 235-242.
Crossref
Omid Azimzadeh, Harry Scherthan, Ramesh Yentrapalli, Zarko Barjaktarovic, Marius Ueffing, Marcus Conrad, Frauke Neff, Julia Calzada-Wack, Michaela Aubele, Christian Buske, Michael J. Atkinson, Stefanie M. Hauck & Soile Tapio. (2012) Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation. Journal of Proteomics 75:8, pages 2384-2395.
Crossref
Kathryn Graham, Kim Moran-Jones, Owen J. Sansom, Valerie G. Brunton & Margaret C. Frame. (2011) FAK Deletion Promotes p53-Mediated Induction of p21, DNA-Damage Responses and Radio-Resistance in Advanced Squamous Cancer Cells. PLoS ONE 6:12, pages e27806.
Crossref
C Jean, P Gravelle, J-J Fournie & G Laurent. (2011) Influence of stress on extracellular matrix and integrin biology. Oncogene 30:24, pages 2697-2706.
Crossref
Iris Eke & Nils Cordes. (2011) Radiobiology goes 3D: How ECM and cell morphology impact on cell survival after irradiation. Radiotherapy and Oncology 99:3, pages 271-278.
Crossref
Iris Eke & Nils Cordes. (2011) Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures. Radiotherapy and Oncology 99:3, pages 279-286.
Crossref
Bo Deng, Wei Huang, Qun-You Tan, Xiao-Qing Fan, Yao-Guang Jiang, Ling Liu, Ya-Yi Zhong, Yong-Gang Liang & Ru-Wen Wang. (2012) Breast Cancer Anti-Estrogen Resistance Protein 1 (BCAR1/p130cas) in Pulmonary Disease Tissue and Serum. Molecular Diagnosis & Therapy 15:1, pages 31-40.
Crossref
E.J. Tocce, S.J. Liliensiek, M.J. Wilson, B. Yanez-Soto, P.F. Nealey & C.J. Murphy. 2011. Comprehensive Biomaterials. Comprehensive Biomaterials 527 546 .
Nadezhda Tikhmyanova, Joy L. Little & Erica A. Golemis. (2009) CAS proteins in normal and pathological cell growth control. Cellular and Molecular Life Sciences 67:7, pages 1025-1048.
Crossref
Stephanie Hehlgans, Inga Lange, Iris Eke & Nils Cordes. (2009) 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. Radiotherapy and Oncology 92:3, pages 371-378.
Crossref
Stephanie Hehlgans, Michael Haase & Nils Cordes. (2007) Signalling via integrins: Implications for cell survival and anticancer strategies. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1775:1, pages 163-180.
Crossref
Nils Cordes. (2006) Integrin-mediated cell–matrix interactions for prosurvival and antiapoptotic signaling after genotoxic injury. Cancer Letters 242:1, pages 11-19.
Crossref
Stephana Carelli, Giorgia Zadra, Valentina Vaira, Monica Falleni, Luca Bottiglieri, Mario Nosotti, Anna Maria Di Giulio, Alfredo Gorio & Silvano Bosari. (2006) Up-regulation of focal adhesion kinase in non-small cell lung cancer. Lung Cancer 53:3, pages 263-271.
Crossref
N Cordes, J Seidler, R Durzok, H Geinitz & C Brakebusch. (2005) β1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury. Oncogene 25:9, pages 1378-1390.
Crossref
Nils Cordes. 2006. Cell Adhesion and Cytoskeletal Molecules in Metastasis. Cell Adhesion and Cytoskeletal Molecules in Metastasis 141 162 .
Young Min Chung, Byoung-Gie Kim, Chang-Soo Park, Seung Jae Huh, Jhingook Kim, Jong Kuk Park, Sun Mi Cho, Byung Soo Kim, Jun Suk Kim, Young Do Yoo & Duk-Soo Bae. (2005) Increased expression of ICAM-3 is associated with radiation resistance in cervical cancer. International Journal of Cancer 117:2, pages 194-201.
Crossref
N Cordes & V Meineke. (2005) Modification of the cellular radiation survival and proliferation response by cell-matrix interactions: implications for integrin targeting in therapeutic approaches for radiation accident patients. The British Journal of Radiology Supplement_27:1, pages 152-156.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.