210
Views
86
CrossRef citations to date
0
Altmetric
Original

Minor contribution of direct ionization to DNA base damage inducedby heavy ions

, , , &
Pages 119-127 | Received 14 Apr 2005, Accepted 11 Jan 2006, Published online: 03 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Jean Cadet, Dimitar Angelov & J. Richard Wagner. (2022) Hydroxyl radical is predominantly involved in oxidatively generated base damage to cellular DNA exposed to ionizing radiation. International Journal of Radiation Biology 98:11, pages 1684-1690.
Read now
Pinar Demir & Feride Severcan. (2016) Monitoring radiation induced alterations in biological systems, from molecules to tissues, through infrared spectroscopy. Applied Spectroscopy Reviews 51:10, pages 839-863.
Read now
Jean Cadet, J. Richard Wagner, Vladimir Shafirovich & Nicholas E. Geacintov. (2014) One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA. International Journal of Radiation Biology 90:6, pages 423-432.
Read now
Jean Cadet, Steffen Loft, Ryszard Olinski, Mark D. Evans, Karol Bialkowski, J. Richard Wagner, Peter C. Dedon, Peter Møller, Marc M. Greenberg & Marcus S. Cooke. (2012) Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free Radical Research 46:4, pages 367-381.
Read now
Katie M. Konigsfeld, Melissa Lee, Sarah M. Urata, Joe A. Aguilera & Jamie R. Milligan. (2012) Free terminal amines in DNA-binding peptides alter the product distribution from guanine radicals produced by single electron oxidation. International Journal of Radiation Biology 88:3, pages 230-238.
Read now

Articles from other publishers (79)

Yining Jiang, Carine Clavaguéra, Suvasthika IndrajithChantal Houée‐Levin, Giel Berden, Jos Oomens & Debora Scuderi. (2023) OH Radical‐Induced Oxidation in Nucleosides and Nucleotides Unraveled by Tandem Mass Spectrometry and Infrared Multiple Photon Dissociation Spectroscopy. ChemPhysChem 24:23.
Crossref
Anne-Sophie Wozny & Claire Rodriguez-Lafrasse. (2023) The ‘stealth-bomber’ paradigm for deciphering the tumour response to carbon-ion irradiation. British Journal of Cancer 128:8, pages 1429-1438.
Crossref
Mario Alcocer-Ávila, Caterina Monini, Micaela Cunha, Étienne Testa & Michaël Beuve. (2023) Formalism of the NanOx biophysical model for radiotherapy applications. Frontiers in Physics 11.
Crossref
N. Medvedev, A. E. Volkov, R. Rymzhanov, F. Akhmetov, S. Gorbunov, R. Voronkov & P. Babaev. (2023) Frontiers, challenges, and solutions in modeling of swift heavy ion effects in materials. Journal of Applied Physics 133:10.
Crossref
Dimitar Angelov, Ramachandran Boopathi, Imtiaz Nisar Lone, Hervé Menoni, Stefan Dimitrov & Jean Cadet. (2022) Capturing Protein–Nucleic Acid Interactions by High‐Intensity Laser‐Induced Covalent Cross‐Linking † . Photochemistry and Photobiology 99:2, pages 296-312.
Crossref
Zheng Li, Chang He, Xiangming Zhou, Lixiang Wang, Ying Zhang, Guangfu Feng & Jun Fang. (2022) FeOOH nanosheet assisted metal ion coordination with porphyrins for rapid detection and removal of cadmium ions in water. Analytical Methods 14:47, pages 4947-4955.
Crossref
John M. Danforth, Luc Provencher & Aaron A. Goodarzi. (2022) Chromatin and the Cellular Response to Particle Radiation-Induced Oxidative and Clustered DNA Damage. Frontiers in Cell and Developmental Biology 10.
Crossref
Qian Li, Guoping Zhao, Wei Han, Shengmin Xu & Lijun Wu. (2022) Radiation target: Moving from theory to practice. Nuclear Analysis 1:2, pages 100024.
Crossref
Dimitar Angelov, Imtiaz Nisar Lone, Hervé Menoni & Jean Cadet. (2022) Interstrand Crosslinking Involving Guanine: A New Major UVC Laser‐Induced Biphotonic Oxidatively Generated DNA Damage † . Photochemistry and Photobiology 98:3, pages 662-670.
Crossref
Terry Park, Ingu Lee, Seong-Jin Son, Youngbin Na & Do-Kyeong Ko. (2022) Photochemical pathways of 8-oxo-2′-deoxyguanosine under photodegradation. AIP Advances 12:2.
Crossref
Peter Møller & Martin Roursgaard. (2021) Biomarkers of DNA Oxidation Products: Links to Exposure and Disease in Public Health Studies. Chemical Research in Toxicology 34:11, pages 2235-2250.
Crossref
Maurício S. Baptista, Jean Cadet, Alexander Greer & Andrés H. Thomas. (2021) Photosensitization Reactions of Biomolecules: Definition, Targets and Mechanisms. Photochemistry and Photobiology 97:6, pages 1456-1483.
Crossref
Yingxia Gao, Yi Zheng & Léon Sanche. (2021) Low-Energy Electron Damage to Condensed-Phase DNA and Its Constituents. International Journal of Molecular Sciences 22:15, pages 7879.
Crossref
Ahmed Shahat, Khadiza Tul Kubra, Md. Shad Salman, Md. Nazmul Hasan & Md. Munjur Hasan. (2021) Novel solid-state sensor material for efficient cadmium(II) detection and capturing from wastewater. Microchemical Journal 164, pages 105967.
Crossref
Tamon Kusumoto, Ryo Ogawara, Kazuyo Igawa, Kentaro Baba, Teruaki Konishi, Yoshiya Furusawa & Satoshi Kodaira. (2021) Scaling parameter of the lethal effect of mammalian cells based on radiation-induced OH radicals: effectiveness of direct action in radiation therapy. Journal of Radiation Research 62:1, pages 86-93.
Crossref
Durairaj Jansi Rani, Rajendran Mala, Preetha Mohan, Ravichandran Keerthana, Nagaiah Hari Prasath & Arul Selvaraj Ruby Celsia. (2020) Chitosan nanoparticle-mediated delivery of curcumin and phycocyanin for photodynamic therapy against biofilm forming bacteria. Materials Express 10:11, pages 1854-1870.
Crossref
Magdalena Szatkowska & Renata Krupa. (2020) Regulation of DNA Damage Response and Homologous Recombination Repair by microRNA in Human Cells Exposed to Ionizing Radiation. Cancers 12:7, pages 1838.
Crossref
Jessica S. Helm & Ruthann A. Rudel. (2020) Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with hormonal regulation of the breast. Archives of Toxicology 94:5, pages 1511-1549.
Crossref
Ofelia R. Alzueta, Jean Cadet, M. Consuelo Cuquerella & Miguel A. Miranda. (2020) Photosensitised biphotonic chemistry of pyrimidine derivatives. Organic & Biomolecular Chemistry 18:12, pages 2227-2232.
Crossref
Vincent Murray, Megan E. Hardie & Shweta D. Gautam. (2019) Comparison of Different Methods to Determine the DNA Sequence Preference of Ionising Radiation-Induced DNA Damage. Genes 11:1, pages 8.
Crossref
Andrea M Kaminski, Kishore K Chiruvella, Dale A Ramsden, Thomas A Kunkel, Katarzyna Bebenek & Lars C Pedersen. (2019) Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2′-guanosine. Nucleic Acids Research 47:17, pages 9410-9422.
Crossref
Hakim Belmouaddine, Guru S. Madugundu, J. Richard Wagner, Arnaud Couairon, Daniel Houde & Léon Sanche. (2019) DNA Base Modifications Mediated by Femtosecond Laser-Induced Cold Low-Density Plasma in Aqueous Solutions. The Journal of Physical Chemistry Letters 10:11, pages 2753-2760.
Crossref
David Chauvin, Jérémy Bell, Isabelle Leray, Isabelle Ledoux-Rak & Chi Thanh Nguyen. (2019) Label-free optofluidic sensor based on polymeric microresonator for the detection of cadmium ions in tap water. Sensors and Actuators B: Chemical 280, pages 77-85.
Crossref
Weichao Zhao, Nan Hu, Dexin Ding, Dingxin Long, Sheng Li, Guangyue Li & Hui Zhang. (2018) Developmental toxicity and apoptosis in zebrafish embryos induced by low-dose γ-ray irradiation. Environmental Science and Pollution Research 26:4, pages 3869-3881.
Crossref
Jean Cadet, J. Richard Wagner & Dimitar Angelov. (2018) Biphotonic Ionization of DNA : From Model Studies to Cell . Photochemistry and Photobiology 95:1, pages 59-72.
Crossref
Jean Cadet & Thierry Douki. (2020) Formation of UV-induced DNA damage contributing to skin cancer development. Photochemical & Photobiological Sciences 17:12, pages 1816-1841.
Crossref
Jean-Pierre PougetAlexandros G. GeorgakilasJean-Luc Ravanat. (2018) Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk/Benefit Analysis. Antioxidants & Redox Signaling 29:15, pages 1447-1487.
Crossref
J.-L. Ravanat. (2018) Endogenous natural and radiation-induced DNA lesions: differences and similarities and possible implications for human health and radiological protection. Radioprotection 53:4, pages 241-248.
Crossref
Shweta D. Gautam, Megan E. Hardie & Vincent Murray. (2018) The Sequence Preference of Gamma-Radiation-Induced Damage in End-Labeled DNA after Heat Treatment. Radiation Research 189:3, pages 238-250.
Crossref
Maurício S. Baptista, Jean Cadet, Paolo Di Mascio, Ashwini A. Ghogare, Alexander Greer, Michael R. Hamblin, Carolina Lorente, Silvia Cristina Nunez, Martha Simões Ribeiro, Andrés H. Thomas, Mariana Vignoni & Tania Mateus Yoshimura. (2017) Type I and Type II Photosensitized Oxidation Reactions: Guidelines and Mechanistic Pathways. Photochemistry and Photobiology 93:4, pages 912-919.
Crossref
Jean Cadet, Kelvin J.A. Davies, Marisa HG Medeiros, Paolo Di Mascio & J. Richard Wagner. (2017) Formation and repair of oxidatively generated damage in cellular DNA. Free Radical Biology and Medicine 107, pages 13-34.
Crossref
Anne-Sophie Wozny, Alexandra Lauret, Priscillia Battiston-Montagne, Jean-Baptiste Guy, Michael Beuve, Micaela Cunha, Yannick Saintigny, Emilie Blond, Nicolas Magne, Philippe Lalle, Dominique Ardail, Gersende Alphonse & Claire Rodriguez-Lafrasse. (2017) Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect. British Journal of Cancer 116:10, pages 1340-1349.
Crossref
Ewa Barbier, Arnaud Lagorce, Amine Hachemi, Murielle Dutertre, Aurore Gorlas, Lucie Morand, Christine Saint-Pierre, Jean-Luc Ravanat, Thierry Douki, Jean Armengaud, Didier Gasparutto, Fabrice Confalonieri & Jean Breton. (2016) Oxidative DNA Damage and Repair in the Radioresistant Archaeon Thermococcus gammatolerans . Chemical Research in Toxicology 29:11, pages 1796-1809.
Crossref
Jean-Luc Ravanat & Thierry Douki. (2016) UV and ionizing radiations induced DNA damage, differences and similarities. Radiation Physics and Chemistry 128, pages 92-102.
Crossref
Jean Cadet & J. Richard Wagner. (2016) Radiation-induced damage to cellular DNA: Chemical nature and mechanisms of lesion formation. Radiation Physics and Chemistry 128, pages 54-59.
Crossref
Florent Durantel, Emmanuel Balanzat, Amine Cassimi, François Chevalier, Yvette Ngono-Ravache, Toiammou Madi, Jean-Christophe Poully, Jean-Marc Ramillon, Hermann Rothard, Frédéric Ropars, Lucas Schwob, Isabelle Testard & Yannick Saintigny. (2016) Dosimetry for radiobiology experiments at GANIL. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 816, pages 70-77.
Crossref
Ryszard Olinski, Marta Starczak & Daniel Gackowski. (2016) Enigmatic 5-hydroxymethyluracil: Oxidatively modified base, epigenetic mark or both?. Mutation Research/Reviews in Mutation Research 767, pages 59-66.
Crossref
Michael Beuve, Jean-Michel Moreau, Claire Rodriguez & Etienne Testa. (2015) Biological systems: from water radiolysis to carbon ion radiotherapy. Journal of Physics: Conference Series 629, pages 012004.
Crossref
Jean Cadet, Thierry Douki & Jean-Luc Ravanat. (2015) Oxidatively Generated Damage to Cellular DNA by UVB and UVA Radiation , . Photochemistry and Photobiology 91:1, pages 140-155.
Crossref
D. Pang, J. S. Nico, L. Karam, O. Timofeeva, W. F. Blakely, A. Dritschilo, M. Dizdaroglu & P. Jaruga. (2014) Significant disparity in base and sugar damage in DNA resulting from neutron and electron irradiation. Journal of Radiation Research 55:6, pages 1081-1088.
Crossref
Jolanta Guz, Daniel Gackowski, Marek Foksinski, Rafal Rozalski & Ryszard Olinski. (2014) Comparison of the Absolute Level of Epigenetic Marks 5-Methylcytosine, 5-Hydroxymethylcytosine, and 5-Hydroxymethyluracil Between Human Leukocytes and Sperm1. Biology of Reproduction 91:3.
Crossref
Jean Cadet & J. Richard Wagner. (2014) Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: Similarities and differences. Archives of Biochemistry and Biophysics 557, pages 47-54.
Crossref
G. S. Madugundu, J. Cadet & J. R. Wagner. (2014) Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA. Nucleic Acids Research 42:11, pages 7450-7460.
Crossref
Ewelina Zarakowska, Daniel Gackowski, Marek Foksinski & Ryszard Olinski. (2014) Are 8-oxoguanine (8-oxoGua) and 5-hydroxymethyluracil (5-hmUra) oxidatively damaged DNA bases or transcription (epigenetic) marks?. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 764-765, pages 58-63.
Crossref
J-L Ravanat, J Breton, T Douki, D Gasparutto, A Grand, W Rachidi & S Sauvaigo. (2014) Radiation-mediated formation of complex damage to DNA: a chemical aspect overview. The British Journal of Radiology 87:1035, pages 20130715.
Crossref
Jean Cadet, André Grand & Thierry Douki. 2015. Photoinduced Phenomena in Nucleic Acids II. Photoinduced Phenomena in Nucleic Acids II 249 275 .
Ryoichi Hirayama, Atsushi Ito, Miho Noguchi, Yoshitaka Matsumoto, Akiko Uzawa, Gen Kobashi, Ryuichi Okayasu & Yoshiya Furusawa. (2013) OH Radicals from the Indirect Actions of X-Rays Induce Cell Lethality and Mediate the Majority of the Oxygen Enhancement Effect. Radiation Research 180:5, pages 514-523.
Crossref
Elahe Alizadeh & Léon Sanche. (2013) Role of Humidity and Oxygen Level on Damage to DNA Induced by Soft X-rays and Low-Energy Electrons. The Journal of Physical Chemistry C 117:43, pages 22445-22453.
Crossref
Guru S. Madugundu, J. Richard Wagner, Jean Cadet, Konstantin Kropachev, Byeong Hwa Yun, Nicholas E. Geacintov & Vladimir Shafirovich. (2013) Generation of Guanine–Thymine Cross-Links in Human Cells by One-Electron Oxidation Mechanisms. Chemical Research in Toxicology 26:7, pages 1031-1033.
Crossref
Jean Cadet, Thierry Douki, Jean-Luc Ravanat & J. Richard Wagner. 2013. Frontiers of Bioanalytical Chemistry. Frontiers of Bioanalytical Chemistry 269 288 .
Jean Cadet, Jean-Luc Ravanat, Marisa TavernaPorro, Hervé Menoni & Dimitar Angelov. (2012) Oxidatively generated complex DNA damage: Tandem and clustered lesions. Cancer Letters 327:1-2, pages 5-15.
Crossref
Jean Cadet, Thierry Douki, Jean-Luc Ravanat & J. Richard Wagner. (2012) Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts. Bioanalytical Reviews 4:2-4, pages 55-74.
Crossref
Jean Cadet, Stéphane Mouret, Jean-Luc Ravanat & Thierry Douki. (2012) Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†. Photochemistry and Photobiology 88:5, pages 1048-1065.
Crossref
C. Rodriguez-Lafrasse & J. Balosso. (2012) De la trace des ions carbone à l’efficacité thérapeutique de l’hadronthérapie. Cancer/Radiothérapie 16:1, pages 16-24.
Crossref
Jean Cadet, Thierry Douki, Didier Gasparutto, Jean‐Luc Ravanat & J.  Richard Wagner. 2012. Encyclopedia of Radicals in Chemistry, Biology and Materials. Encyclopedia of Radicals in Chemistry, Biology and Materials.
Xin Zhou, Ning Li, Yanling Wang, Yipei Wang, Xin Zhang & Hong Zhang. (2011) Effects of X-irradiation on mitochondrial DNA damage and its supercoiling formation change. Mitochondrion 11:6, pages 886-892.
Crossref
Jean Cadet, Thierry Douki & Jean-Luc Ravanat. (2011) Measurement of oxidatively generated base damage in cellular DNA. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 711:1-2, pages 3-12.
Crossref
Jean Cadet & Thierry Douki. (2011) Oxidatively Generated Damage to DNA by UVA Radiation in Cells and Human Skin. Journal of Investigative Dermatology 131:5, pages 1005-1007.
Crossref
Jean Cadet, Thierry Douki & Jean-Luc Ravanat. 2011. Studies on Experimental Models. Studies on Experimental Models 579 604 .
Alexandros G. Georgakilas, Stewart M. Holt, Jessica M. Hair & Charles W. Loftin. (2010) Measurement of Oxidatively‐Induced Clustered DNA Lesions Using a Novel Adaptation of Single Cell Gel Electrophoresis (Comet Assay). Current Protocols in Cell Biology 49:1.
Crossref
Jessica M. Hair, Georgia I. Terzoudi, Vasiliki I. Hatzi, Katie A. Lehockey, Devika Srivastava, Weixin Wang, Gabriel E. Pantelias & Alexandros G. Georgakilas. (2010) BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions. Chemico-Biological Interactions 188:2, pages 350-358.
Crossref
Jean Cadet, Thierry Douki & Jean-Luc Ravanat. (2010) Oxidatively generated base damage to cellular DNA. Free Radical Biology and Medicine 49:1, pages 9-21.
Crossref
Jean Cadet, Thierry Douki & Jean‐Luc Ravanat. 2010. The Chemical Biology of DNA Damage. The Chemical Biology of DNA Damage 53 80 .
Karin Magnander, Ragnar Hultborn, Kristina Claesson & Kecke Elmroth. (2010) Clustered DNA Damage in Irradiated Human Diploid Fibroblasts: Influence of Chromatin Organization. Radiation Research 173:3, pages 272-282.
Crossref
Nourreddine Belmadoui, Fabien Boussicault, Maurizio Guerra, Jean-Luc Ravanat, Chryssostomos Chatgilialoglu & Jean Cadet. (2010) Radiation-induced formation of purine 5′,8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen. Organic & Biomolecular Chemistry 8:14, pages 3211.
Crossref
Jean Cadet, Thierry Douki, Didier Gasparutto, Jean‐Luc Ravanat & J. Richard Wagner. 2009. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry 69 97 .
Jean Cadet, Thierry Douki, Jean-Luc Ravanat & Paolo Di Mascio. (2009) Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation. Photochemical & Photobiological Sciences 8:7, pages 903-911.
Crossref
S. Lacombe & C. Le Sech. (2009) Advances in radiation biology: Radiosensitization in DNA and living cells. Surface Science 603:10-12, pages 1953-1960.
Crossref
A. Kish, G. Kirkali, C. Robinson, R. Rosenblatt, P. Jaruga, M. Dizdaroglu & J. DiRuggiero. (2009) Salt shield: intracellular salts provide cellular protection against ionizing radiation in the halophilic archaeon, Halobacterium salinarum NRC-1 . Environmental Microbiology 11:5, pages 1066-1078.
Crossref
Ivano Tavernelli, Marie-Pierre Gaigeot, Rodolphe Vuilleumier, Carlos Stia, Marie-Anne Hervé du Penhoat & Marie-Françoise Politis. (2008) Time-Dependent Density Functional Theory Molecular Dynamics Simulations of Liquid Water Radiolysis. ChemPhysChem 9:14, pages 2099-2103.
Crossref
Thierry Douki, Zakaria Ksoury, Caroline Marie, Alain Favier, Jean-Luc Ravanat & Anne Maitre. (2008) Genotoxicity of Combined Exposure to Polycyclic Aromatic Hydrocarbons and UVA-A Mechanistic Study. Photochemistry and Photobiology 84:5, pages 1133-1140.
Crossref
Jean Cadet & Paolo Di Mascio. 2008. Modified Nucleosides. Modified Nucleosides 29 47 .
Jean Cadet, Thierry Douki & Jean-Luc Ravanat. (2008) Oxidatively Generated Damage to the Guanine Moiety of DNA: Mechanistic Aspects and Formation in Cells. Accounts of Chemical Research 41:8, pages 1075-1083.
Crossref
Tracey A. Dobbs, Philip Palmer, Zoitsa Maniou, Martine E. Lomax & Peter O’Neill. (2008) Interplay of two major repair pathways in the processing of complex double-strand DNA breaks. DNA Repair 7:8, pages 1372-1383.
Crossref
Dave C. Francisco, Prakash Peddi, Jessica M. Hair, Brittany A. Flood, Angela M. Cecil, Peter T. Kalogerinis, George Sigounas & Alexandros G. Georgakilas. (2008) Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and nonmalignant MCF-10A cells. Free Radical Biology and Medicine 44:4, pages 558-569.
Crossref
Christophe Hennequin, Laurent Quero & Vincent Favaudon. (2008) Déterminants et facteurs prédictifs pour la radiosensibilité tumorale. Cancer/Radiothérapie 12:1, pages 3-13.
Crossref
Guido Frosina. (2007) The current evidence for defective repair of oxidatively damaged DNA in Cockayne syndrome. Free Radical Biology and Medicine 43:2, pages 165-177.
Crossref
A. Ly, J.A. Aguilera & J.R. Milligan. (2007) Kinetic behavior of the reaction between hydroxyl radical and the SV40 minichromosome. Radiation Physics and Chemistry 76:6, pages 982-987.
Crossref
Jean Cadet, Thierry Douki, Carine Badouard, Alain Favier & Jean-Luc Ravanat. 2007. Oxidative Damage to Nucleic Acids. Oxidative Damage to Nucleic Acids 1 13 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.