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International Journal of Radiation Biology Volume 84, 2008 - Issue 1
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Original Article

Spatio-temporal localization of HIF-1α and COX-2 during irradiation-induced oral mucositis in a rat model system

Chong-Jin Feng Department of Stomatology, The First Affiliated Hospital, Sun Yat-Sen University, GuangzhouCorrespondence[email protected]
,
Jun-Bing Guo Department of Stomatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou
,
Hong-Wei Jiang Affiliated Dental Hospital, Sun Yat-Sen University, Guangzhou
,
Shuang-Xi Zhu Department of Stomatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou
,
Chun-Yang Li Affiliated Dental Hospital, Sun Yat-Sen University, Guangzhou
,
Bin Cheng Affiliated Dental Hospital, Sun Yat-Sen University, Guangzhou
,
Yong Chen Department of Radiotherapy, Affiliated Cancer Hospital, Sun Yat-Sen University Guangzhou, P.R. China
&
Han-Yu Wang Department of Radiotherapy, Affiliated Cancer Hospital, Sun Yat-Sen University Guangzhou, P.R. China
 show all
Pages 35-45 | Received 30 Dec 2006, Accepted 01 Aug 2007, Published online: 03 Jul 2009

Citations (9)

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Yunxia Liu, Yun Ye, Guanqun Xie, Yefeng Xu, Miao Cheng, Chunling Li, Mengqi Qu & Feiye Zhu. (2023) Pharmacological Mechanism of Sancao Yuyang Decoction in the Treatment of Oral Mucositis Based on Network Pharmacology and Experimental Validation. Drug Design, Development and Therapy 17, pages 55-74.
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Articles from other publishers (8)

Fatemeh Madani, Sohrab Kazemi, Fatemeh Shirafkan, Mandana Lotfi, Seyed M. Hosseini & Ali A. Moghadamnia. (2023) Thymoquinone protects against 5‐Fluorouracil‐induced mucositis by NF‐κβ and HIF‐1 mechanisms in mice. Journal of Biochemical and Molecular Toxicology.
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Sebastian Zschaeck, Klaus Zöphel, Annekatrin Seidlitz, Daniel Zips, Jörg Kotzerke, Michael Baumann, Esther G.C. Troost, Steffen Löck & Mechthild Krause. (2021) Generation of biological hypotheses by functional imaging links tumor hypoxia to radiation induced tissue inflammation/glucose uptake in head and neck cancer. Radiotherapy and Oncology 155, pages 204-211.
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Jon Kirk, Nirav Shah, Braxton Noll, Craig B. Stevens, Marshall Lawler, Farah B. Mougeot & Jean-Luc C. Mougeot. (2018) Text mining-based in silico drug discovery in oral mucositis caused by high-dose cancer therapy. Supportive Care in Cancer 26:8, pages 2695-2705.
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Sylvia Gruber, Marlene Arnold, Nilsu Cini, Victoria Gernedl, Sabine Hetzendorfer, Lisa-Marie Kowald, Peter Kuess, Julia Mayer, Susanne Morava, Stephanie Pfaffinger, Andreas Rohorzka & Wolfgang Dörr. (2018) Radioprotective Effects of Dermatan Sulfate in a Preclinical Model of Oral Mucositis—Targeting Inflammation, Hypoxia and Junction Proteins without Stimulating Proliferation. International Journal of Molecular Sciences 19:6, pages 1684.
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Takako Nakashima, Naoya Uematsu & Kazushi Sakurai. (2017) Intra-oral administration of rebamipide liquid prevents tongue injuries induced by X-ray irradiation in rats. Supportive Care in Cancer 25:7, pages 2205-2213.
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Rajesh V. Lalla, Linda E. Choquette, Kathleen F. Curley, Robert J. Dowsett, Richard S. Feinn, Upendra P. Hegde, Carol C. Pilbeam, Andrew L. Salner, Stephen T. Sonis & Douglas E. Peterson. (2014) Randomized double-blind placebo-controlled trial of celecoxib for oral mucositis in patients receiving radiation therapy for head and neck cancer. Oral Oncology 50:11, pages 1098-1103.
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Tong Wu, Lihua Jia, Rui Du, Xiaoan Tao, Jinou Chen & Bin Cheng. (2011) Genome-wide analysis reveals the active roles of keratinocytes in oral mucosal adaptive immune response. Experimental Biology and Medicine 236:7, pages 832-843.
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Rajesh V. Lalla, Carol C. Pilbeam, Stephen J. Walsh, Stephen T. Sonis, Dorothy M. K. Keefe & Douglas E. Peterson. (2009) Role of the cyclooxygenase pathway in chemotherapy-induced oral mucositis: a pilot study. Supportive Care in Cancer 18:1, pages 95-103.
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