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International Journal of Radiation Biology Volume 93, 2017 - Issue 8
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Original Articles

Synergistic effect of Ebselen and gamma radiation on breast cancer cells

Noura M. ThabetRadiation Biology Department, National Centre for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Cairo, EgyptCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-0073-7347
ORCID Icon &
Enas M. MoustafaRadiation Biology Department, National Centre for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Cairo, EgyptORCID Iconhttp://orcid.org/0000-0003-0484-5759
ORCID Icon
Pages 784-792 | Received 26 Nov 2016, Accepted 25 Apr 2017, Published online: 17 May 2017

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Enas Mahmoud Moustafa, Asmaa A. Hassan, Iman Hesham EL-Khashab & Somaya Zakaria Mansour. (2021) The role of Garcinol in abrogating cyclophosphamide/radiation nephrotoxicity via suppressing Mincle/Syk/NF-κB signaling pathway. Toxin Reviews 40:4, pages 791-802.
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Articles from other publishers (21)

Mudan Guo, En Zhang, Guiling Wang, Rui Ding, Xiuying Xu, Pengjue Fan, Yimin Zheng & Doudou Xu. (2023) Synthesis and in-vitro study of a novel ligustrazine diselenide as a potential chemotherapy drug for lung adenocarcinoma. Biomedicine & Pharmacotherapy 165, pages 114699.
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Hamza Malik Okuyan, Ziya Yurtal, İhsan Karaboğa, Filiz Kaçmaz & Aydıner Kalacı. (2022) Ebselen, an Active Seleno-Organic Compound, Alleviates Articular Cartilage Degeneration in a Rat Model of Knee Osteoarthritis. Biological Trace Element Research 201:8, pages 3919-3927.
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Noura M. Thabet, Mohamed K. Abdel-Rafei & Mohamed M. Amin. (2023) Fractionated whole body γ-irradiation aggravates arthritic severity via boosting NLRP3 and RANKL expression in adjuvant-induced arthritis model: the mitigative potential of ebselen. Inflammopharmacology 31:4, pages 1929-1949.
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Eluri Pavitra, Jyothsna Kancharla, Vivek Kumar Gupta, Kiran Prasad, Ju Yong Sung, Jigyeong Kim, Mandava Bhuvan Tej, Rino Choi, Jeong-Hwan Lee, Young-Kyu Han, Ganji Seeta Rama Raju, LVKS Bhaskar & Yun Suk Huh. (2023) The role of NF-κB in breast cancer initiation, growth, metastasis, and resistance to chemotherapy. Biomedicine & Pharmacotherapy 163, pages 114822.
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Qian Chen, Liangfang Shen & Shan Li. (2023) Emerging role of inositol monophosphatase in cancer. Biomedicine & Pharmacotherapy 161, pages 114442.
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Mohamed K. Abdel-Rafei, Moustafa A. Askar, Khaled S. Azab, Gharieb S. El-Sayyad, Mohamed Abd El Kodous, Neama M. El Fatih, Ghada El Tawill & Noura M. Thabet. (2023) FA-HA-Amygdalin@Fe2O3 and/or γ-Rays Affecting SIRT1 Regulation of YAP/TAZ-p53 Signaling and Modulates Tumorigenicity of MDA-MB231 or MCF-7 Cancer Cells. Current Cancer Drug Targets 23:2, pages 118-144.
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Forough Firoozbakht, Iman Rezaeian, Luis Rueda & Alioune Ngom. (2022) Computationally repurposing drugs for breast cancer subtypes using a network-based approach. BMC Bioinformatics 23:1.
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Hongyan Chuai, San-Qi Zhang, Huanrong Bai, Jiyu Li, Yang Wang, Jiajia Sun, Ergang Wen, Jiye Zhang & Minhang Xin. (2021) Small molecule selenium-containing compounds: Recent development and therapeutic applications. European Journal of Medicinal Chemistry 223, pages 113621.
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Mohamed K. Abdel-Rafei, Noura M. Thabet, M. I. A. Abdel Maksoud, M. Abd Elkodous, Go Kawamura, Atsunori Matsuda, A. H. Ashour, Ahmed I. El-Batal & Gharieb S. El-Sayyad. (2021) Influence of Ce3+ Substitution on Antimicrobial and Antibiofilm Properties of ZnCexFe2−xO4 Nanoparticles (X = 0.0, 0.02, 0.04, 0.06, and 0.08) Conjugated with Ebselen and Its Role Subsidised with γ-Radiation in Mitigating Human TNBC and Colorectal Adenocarcinoma Proliferation In Vitro. International Journal of Molecular Sciences 22:18, pages 10171.
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Claudio Santi, Cecilia Scimmi & Luca Sancineto. (2021) Ebselen and Analogues: Pharmacological Properties and Synthetic Strategies for Their Preparation. Molecules 26:14, pages 4230.
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Supriya Bevinakoppamath, Adel Mohammed Saleh Ahmed, Shobha Chikkavaddaraguddi Ramachandra, Prashant Vishwanath & Akila Prashant. (2021) Chemopreventive and Anticancer Property of Selenoproteins in Obese Breast Cancer. Frontiers in Pharmacology 12.
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Asmaa A. Hassan, Enas M. Moustafa, Iman Hesham EL-Khashab & Somaya Z. Mansour. (2021) Mangosteen Hinders Gamma Radiation-Mediated Oxidative Stress and Liver Injury by Down-Regulating TNF-α/NF-κB and Pro-Fibrotic Factor TGF-β1 Inducing Inflammatory Signaling. Dose-Response 19:2, pages 155932582110251.
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Cristina W. Nogueira, Nilda V. Barbosa & João B. T. Rocha. (2021) Toxicology and pharmacology of synthetic organoselenium compounds: an update. Archives of Toxicology 95:4, pages 1179-1226.
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Dominika Radomska, Robert Czarnomysy, Dominik Radomski & Krzysztof Bielawski. (2021) Selenium Compounds as Novel Potential Anticancer Agents. International Journal of Molecular Sciences 22:3, pages 1009.
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Qianqian Lu, Yi Cai, Chenyan Xiang, Tao Wu, Ying Zhao, Jun Wang, Helen Wang & Lili Zou. (2021) Ebselen, a multi-target compound: its effects on biological processes and diseases. Expert Reviews in Molecular Medicine 23.
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Jun Wang, Peng Wang, Chuanjiang Dong, Ying Zhao, Jingxuan Zhou, Chunling Yuan & Lili Zou. (2020) Mechanisms of ebselen as a therapeutic and its pharmacology applications. Future Medicinal Chemistry 12:23, pages 2141-2160.
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Sneha Hariharan & Selvakumar Dharmaraj. (2020) Selenium and selenoproteins: it’s role in regulation of inflammation. Inflammopharmacology 28:3, pages 667-695.
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Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma & Daniel Plano. (2019) Development and Therapeutic Potential of Selenazo Compounds. Journal of Medicinal Chemistry 63:4, pages 1473-1489.
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Enas Mahmoud Moustafa, Laila Ahmed Rashed, Mohammed M. El-Sebaie, Noura Magdy Thabet & Mohamed Khairy Abdel-Rafei. (2020) Crosstalk between ER-stress and apoptosis in irradiated HepG2 cells with gemcitabine: implication of PI3K/AKT and IκB/NF-κB signaling pathways. Journal of Radiation Research and Applied Sciences 13:1, pages 144-154.
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Valentina Gandin, Prajakta Khalkar, Jeremy Braude & Aristi P. Fernandes. (2018) Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment. Free Radical Biology and Medicine 127, pages 80-97.
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Gina Wall, Ashok K. Chaturvedi, Floyd L. WormleyJr.Jr., Nathan P. Wiederhold, Hoja P. Patterson, Thomas F. Patterson & José L. Lopez-Ribot. (2018) Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development. Antimicrobial Agents and Chemotherapy 62:10.
Crossref

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