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Original Article

γ-Radiolysis of Poly(U) in Aqueous Solution. The Role of Primary Sugar and Base Radicals in the Release of Undamaged Uracil

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Pages 247-260 | Received 13 Feb 1984, Accepted 24 Apr 1984, Published online: 03 Jul 2009

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Read on this site (16)

Clemens von Sonntag. (2014) WEISS LECTURECarbohydrate radicals: from ethylene glycol to DNA strand breakage. International Journal of Radiation Biology 90:6, pages 416-422.
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Miral Dizdaroglu & Pawel Jaruga. (2012) Mechanisms of free radical-induced damage to DNA. Free Radical Research 46:4, pages 382-419.
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W. WANG, Y. RAZSKAZOVSKII and M. D. SEVILLA. (1997) Secondary radical attack on DNA nucleotides: reaction by addition to DNA bases and abstraction from sugars. International Journal of Radiation Biology 71:4, pages 387-399.
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S.A. Grachev, E.V. Kropachev & G.I. Litvjakova. (1995) Formation of 5-hydroxy-5,6-dihydrouracil and Release of Undamaged Uracil as a Result of Poly(U) Irradiation in N2O-saturated Aqueous Solution. International Journal of Radiation Biology 68:5, pages 543-551.
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G.D.D. Jones & P. O'Neill. (1990) The Kinetics of Radiation-induced Strand Breakage in Polynucleotides in the Presence of Oxygen: A Time-resolved Light-scattering Study. International Journal of Radiation Biology 57:6, pages 1123-1139.
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David J. Deeble & Clemens Von Sonntag. (1989) Radiation-Induced Release of Undamaged Uracil from Polyuridylic Acid and the Formation of Phosphomonoester end Groups in Irradiated Polynucleotides. Free Radical Research Communications 6:2-3, pages 133-135.
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A.M. Önal, D.G.E. Lemaire, E. Bothe & D. Schulte-Frohlinde. (1988) γ-Radiolysis of Poly(A) in Aqueous Solution: Efficiency of Strand Break Formation by Primary Water Radicals. International Journal of Radiation Biology 53:5, pages 787-796.
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Clemens Von Sonntag. (1987) New Aspects in the Free-Radical Chemistry of Pyrimidine Nucleobases. Free Radical Research Communications 2:4-6, pages 217-224.
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Danielle G.E. Lemaire, Eberhard Bothe & Dietrich Schulte-Frohlinde. (1987) Hydroxyl Radical-induced Strand Break Formation of Poly(U) in Anoxic Solution. Effect of Dithiothreitol and Tetranitromethane. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:2, pages 319-330.
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M. Shahid Akhlaq, Heinz-peter Schuchmann & Clemens Von Sonntag. (1987) The Reverse of the ‘Repair’ Reaction of Thiols: H-abstraction at Carbon by Thiyl Radicals. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:1, pages 91-102.
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David J. Deeble & Clemens Von Sonntag. (1986) Radiolysis of Poly(U) in Oxygenated Solution. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:6, pages 927-936.
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David J. Deeble, Dorothea Schulz & Clemens von Sonntag. (1986) Reactions of OH Radicals with Poly(U) in Deoxygenated Solutions: Sites of OH Radical Attack and the Kinetics of Base Release. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:6, pages 915-926.
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Clemens Von Sonntag & Heinz-Peter Schuchmann. (1985) The Radiolysis of Pyrimidines in Aqueous Solutions: An Updating Review. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:1, pages 1-34.
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H. Schuessler & H. Hartmann. (1985) Chromatographic Studies on the Radiolysis of DNA in Aqueous Solution. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 47:5, pages 509-521.
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Clemens Von Sonntag. (1984) Weiss Lecture. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 46:5, pages 507-519.
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Articles from other publishers (18)

Deepti Mishra & Sourav Pal. (2009) Ionization potential and structure relaxation of adenine, thymine, guanine and cytosine bases and their base pairs: A quantification of reactive sites. Journal of Molecular Structure: THEOCHEM 902:1-3, pages 96-102.
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Saurabh Das & Parikshit C. Mandal. (2009) Influence of Ni(II) and Fe(III) complexes of 1,2 dihydroxy 9,10 anthraquinone on the modification in calf thymus DNA upon gamma irradiation. Radiation Physics and Chemistry 78:1, pages 37-41.
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Rajib L. Sarma, Murshida Karim & Chitrani Medhi. (2007) Ab initio and DFT studies on nucleobase radicals of nucleotides. Journal of Molecular Structure: THEOCHEM 805:1-3, pages 17-25.
Crossref
S. Cecchini, S. Girouard, M. A. Huels, L. Sanche & D. J. Hunting. (2004) Single-Strand-Specific Radiosensitization of DNA by Bromodeoxyuridine. Radiation Research 162:6, pages 604-615.
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Clemens von Sonntag. (2003) Free-radical-induced chain scission and cross-linking of polymers in aqueous solution—an overview. Radiation Physics and Chemistry 67:3-4, pages 353-359.
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Yue Jiang, Wei-zhen Lin, Si-de Yao, Nian-yun Lin & Da-yuan Zhu. (1999) Fast repair of oxidizing OH adducts of DNA by hydroxycinnamic acid derivatives. A pulse radiolytic study. Radiation Physics and Chemistry 54:4, pages 355-359.
Crossref
Clemens von Sonntag. 1999. Advances in DNA Damage and Repair. Advances in DNA Damage and Repair 407 418 .
Clemens von Sonntag & Heinz‐Peter Schuchmann. (2003) The Elucidation of Peroxyl Radical Reactions in Aqueous Solution with the Help of Radiation‐Chemical Methods. Angewandte Chemie International Edition in English 30:10, pages 1229-1253.
Crossref
Helmut Görner. (1991) Chromophore loss of uracil derivatives and polyuridylic acid in aqueous solution caused by 248 nm laser pulses and continuous UV irradiation: Mechanism of the photohydration of pyrimidines. Journal of Photochemistry and Photobiology B: Biology 10:1-2, pages 91-110.
Crossref
Roman Osman, Karol Miaskiewicz & Harel Weinstein. 1992. Physical and Chemical Mechanisms in Molecular Radiation Biology. Physical and Chemical Mechanisms in Molecular Radiation Biology 423 452 .
Clemens von Sonntag. 1991. Physical and Chemical Mechanisms in Molecular Radiation Biology. Physical and Chemical Mechanisms in Molecular Radiation Biology 287 321 .
Clemens von Sonntag & Heinz-Peter Schuchmann. 1990. Sulfur-Centered Reactive Intermediates in Chemistry and Biology. Sulfur-Centered Reactive Intermediates in Chemistry and Biology 409 414 .
A.W. Jabir, D.J. Deeble, P.A. Wheatley, C.J. Smith, B.J. Parsons, P.C. Beaumont & A.J. Swallow. (1989) DNA modifications as a means of detecting the irradiation of wheat. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 34:6, pages 935-940.
Crossref
Clemens von Sonntag. (1987) Pulse radiolysis of nucleic acids and their base constituents: An updating review. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 30:5-6, pages 313-330.
Crossref
Herbert Schott, Heidereich v. Biedersee, Clemens von Sonntag & Dietrich Schulte‐Frohlinde. (2003) Synthesis of homologues of deoxyribouridylic acid in preparative amounts using the triester method. Die Makromolekulare Chemie 187:4, pages 809-827.
Crossref
Clemens von Sonntag. 1986. Mechanisms of DNA Damage and Repair. Mechanisms of DNA Damage and Repair 51 59 .
Franklin Hutchinson. 1985. Progress in Nucleic Acid Research and Molecular Biology Volume 32. Progress in Nucleic Acid Research and Molecular Biology Volume 32 115 154 .
DIETRICH SCHULTE-FROHLINDE & CLEMENS VON SONNTAG. 1985. Oxidative Stress. Oxidative Stress 11 40 .

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