Advanced search
Publication Cover
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine Volume 51, 1987 - Issue 4
Journal homepage
10
Views
24
CrossRef citations to date
0
Altmetric
Original Article

Hypoxia-selective Radiosensitization of Mammalian Cells by Nitracrine, an Electron-affinic DNA Intercalator

Peter B. Roberts Institute of Nuclear Sciences, Department of Scientific and Industrial Research, Private Bag, Lower Hutt, New Zealand
,
Robert F. Anderson The Gray Laboratory of the Cancer Research Campaign, Mount Vernon Hospital, Northwood, Middlesex, HA6 2RN, U.K.
&
William R. Wilson Section of Oncology, Department of Pathology, University of Auckland School of Medicine, Private Bag, Auckland, New Zealand
Pages 641-654 | Received 15 Sep 1986, Accepted 14 Nov 1986, Published online: 03 Jul 2009

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

I. G. C. Robertson, T. J. Bland & B. D. Palmer. (1996) Effect of substituents on the metabolism of nitracrine in rat. Xenobiotica 26:5, pages 559-569.
Read now

Articles from other publishers (23)

Karim Asadpour‐Zeynali, Mir Reza Majidi, Parvaneh Najafi‐Marandi & Zinalabedin Norysaray. (2013) Electrocatalytic Reduction of Metronidazole on Bismuth Modified Pencil‐lead Electrode. Journal of the Chinese Chemical Society 60:10, pages 1253-1259.
Crossref
Ambarish Ray, Parikshit Chandra Mandal, Atish Dipankar Jana, William S. Sheldrick, Swastik Mondal, Monika Mukherjee & Mahammad Ali. (2008) Cyanometallate incorporated supramolecular networks based on a nitroalkyl-substituted CuIIN4 precursor: Synthesis, crystal structure, thermal and electrochemical studies. Polyhedron 27:14, pages 3112-3122.
Crossref
G-One Ahn & J. Martin Brown. 2006. Multimodal Concepts for Integration of Cytotoxic Drugs. Multimodal Concepts for Integration of Cytotoxic Drugs 67 91 .
P.C Mandal. (2004) Reactions of the nitro radical anion of metronidazole in aqueous and mixed solvent: a cyclic voltammetric study. Journal of Electroanalytical Chemistry 570:1, pages 55-61.
Crossref
Marek Gniazdowski & Leszek Szmigiero. (1995) Nitracrine and its congeners—An overview. General Pharmacology: The Vascular System 26:3, pages 473-481.
Crossref
Bronwyn G. Slim, William A. Denny & William R. Wilson. (1994) Does DNA targeting affect the cytotoxicity and cell uptake of basic nitroquinoline bioreductive drugs?. International Journal of Radiation Oncology*Biology*Physics 29:2, pages 311-315.
Crossref
M. GUICHARD & E. LARTIGAU. 1994. Relative Radiation Sensitivities of Human Organ Systems, Part IV. Relative Radiation Sensitivities of Human Organ Systems, Part IV 123 147 .
K. U. Ingold. 1994. Nitrogen-Centered Radicals, Aminoxyls and Related Radicals. Nitrogen-Centered Radicals, Aminoxyls and Related Radicals 547 555 .
Małgorzata Walicka, Leszek Szmigiero, Ewa Ciesielska & Iwona Gradzka. (1993) Are lethal effects of nitracrine on L5178Y cell sublines associated with DNA-protein crosslinks?. Biochemical Pharmacology 46:4, pages 615-620.
Crossref
Maria V. Papadopoulou, Michael W. Epperly, Donna S. Shields & William D. Bloomer. (2005) Radiosensitization and Hypoxic Cell Toxicity of NLA‐1 and NLA‐2, Two New Bioreductive Compounds. Japanese Journal of Cancer Research 83:4, pages 410-414.
Crossref
William R. Wilson & William A. Denny. 1992. Congress Proceedings. Congress Proceedings 796 801 .
Robert F. Anderson, William A. Denny, Peter B. Roberts, Peter Wardman, John White & William R. Wilson. (1992) Correlation of the radiosensitization potency afforded by nitroacridine intercalators with their electron scavenging efficiency in DNA. International Journal of Radiation Oncology*Biology*Physics 22:3, pages 537-540.
Crossref
R.F. Martin & L. Denison. (1992) DNA ligands as radiomodifiers: Studies with minor-groove binding bibenzimidazoles. International Journal of Radiation Oncology*Biology*Physics 23:3, pages 579-584.
Crossref
Isabel Freitas & Gian Franco Baronzio. (1991) New trends in photobiology. Journal of Photochemistry and Photobiology B: Biology 11:1, pages 3-30.
Crossref
Mark J. Suto. 1991. 151 160 .
M.P. Cornago, M.C. Lopez Zumel, M.V. Alvarez & M.C. Izquierdo. (1990) Glyoxylic compounds as radiosensitizers of hypoxic cells. Biochemical Medicine and Metabolic Biology 43:3, pages 253-262.
Crossref
W. A. Denny. 1990. The Chemistry of Antitumour Agents. The Chemistry of Antitumour Agents 1 29 .
R. Panicucci, R. Heal, K. Laderoute, D. Cowan, R.A. Mcclelland & A.M. Rauth. (1989) NLP-1: A DNA intercalating hypoxic cell radiosensitizer and cytotoxin. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 1039-1043.
Crossref
William R. Wilson & Robert F. Anderson. (1989) The reaction between nitracrine and glutathione: Implications for hypoxic cell radiosensitization and cytotoxicity. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 1001-1005.
Crossref
H.C. Goel & A.R. Roa. (1988) Radiosensitizing effect of camphor on transplantable mammary adenocarcinoma in mice. Cancer Letters 43:1-2, pages 21-27.
Crossref
Lynnette R. Ferguson & Pierre van Zijl. (1988) Mutagenic and clastogenic activity of nitracrine analogues in cultured V79 Chinese hamster cells. Mutation Research/Genetic Toxicology 204:4, pages 655-663.
Crossref
Lynnette R. Ferguson & Pamela M. Turner. (1987) Frameshift mutagenesis by nitracrine analogues in wild-type, uvrB, polA and recA strains of Salmonella typhimurium, with and without plasmid pKM101. Mutation Research/DNA Repair Reports 184:1, pages 13-21.
Crossref
Peter Wardman. (1987) The mechanism of radiosensitization by electron-affinic compounds. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 30:5-6, pages 423-432.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.