Peter Wardman. (2018) Nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes: misonidazole, myths and mistakes. The British Journal of Radiology, pages 20170915.
Crossref
Mahvash Tavassoli & Yae-eun Suh. 2017. Squamous cell Carcinoma. Squamous cell Carcinoma
59
95
.
Muriel Bonnet, Cho Rong Hong, Yongchuan Gu, Robert F. Anderson, William R. Wilson, Frederik B. Pruijn, Jingli Wang, Kevin O. Hicks & Michael P. Hay. (2014) Novel nitroimidazole alkylsulfonamides as hypoxic cell radiosensitisers. Bioorganic & Medicinal Chemistry 22:7, pages 2123-2132.
Crossref
Nilesh K. Wagh, Zhengyuan Zhou, Sunny M. Ogbomo, Wen Shi, Susan K. Brusnahan & Jered C. Garrison. (2012)
Development of Hypoxia Enhanced
111
In-Labeled Bombesin Conjugates: Design, Synthesis, and In Vitro Evaluation in PC-3 Human Prostate Cancer
. Bioconjugate Chemistry 23:3, pages 527-537.
Crossref
Peter Wardman. 2009. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry
295
324
.
Nathan J. Ranalli, Sydney M. Evans & Kevin D. Judy. (2009) Hypoxia in Brain Tumors. Neurosurgery Quarterly 19:1, pages 1-12.
Crossref
P WARDMAN. (2009) The importance of radiation chemistry to radiation and free radical biology (The 2008 Silvanus Thompson Memorial Lecture). The British Journal of Radiology 82:974, pages 89-104.
Crossref
Lyudmila Larina & Valentin LopyrevL. Larina & V. Lopyrev. 2009. Nitroazoles: Synthesis, Structure and Applications. Nitroazoles: Synthesis, Structure and Applications
407
432
.
Cameron J. Koch. (2008)
Importance of Antibody Concentration in the Assessment of Cellular Hypoxia by Flow Cytometry: EF5
1
and Pimonidazole
. Radiation Research 169:6, pages 677-688.
Crossref
P. Wardman. (2007) Chemical Radiosensitizers for Use in Radiotherapy. Clinical Oncology 19:6, pages 397-417.
Crossref
Leo E. Gerweck, Shashirekha Vijayappa & Sergey Kozin. (2006)
Tumor pH controls the
in vivo
efficacy of weak acid and base chemotherapeutics
. Molecular Cancer Therapeutics 5:5, pages 1275-1279.
Crossref
Miriam M. Kleiter, Donald E. Thrall, David E. Malarkey, Xiaoshen Ji, David Y.W. Lee, Shu-Chuan Chou & James A. Raleigh. (2006) A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker. International Journal of Radiation Oncology*Biology*Physics 64:2, pages 592-602.
Crossref
Anna S.E. Ljungkvist, Johan Bussink, Johannes H.A.M. Kaanders, Paulus F.J.W. Rijken, Adrian C. Begg, James A. Raleigh & Albert J. van der Kogel. (2005) Hypoxic cell turnover in different solid tumor lines. International Journal of Radiation Oncology*Biology*Physics 62:4, pages 1157-1168.
Crossref
Sydney M. Evans & Cameron J. Koch. (2003) Prognostic significance of tumor oxygenation in humans. Cancer Letters 195:1, pages 1-16.
Crossref
Donald J. AbrahamEdward A. Bump, Stephen J. Hoffman & William O. Foye. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
151
214
.
P. Wardman. 2001. Radiation Chemistry - Present Status and Future Trends. Radiation Chemistry - Present Status and Future Trends
623
655
.
Andrew S. Kennedy, James A. Raleigh, Gerardo M. Perez, Dennise P. Calkins, Donald E. Thrall, Debra B. Novotny & Mahesh A. Varia. (1997) Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays. International Journal of Radiation Oncology*Biology*Physics 37:4, pages 897-905.
Crossref
Bronwyn G. Slim, William A. Denny & William R. Wilson. (1994) Does DNA targeting affect the cytotoxicity and cell uptake of basic nitroquinoline bioreductive drugs?. International Journal of Radiation Oncology*Biology*Physics 29:2, pages 311-315.
Crossref
John Parrick, Manuchehr Porssa, Lisa K. Davies, Madeleine F. Dennis, Kantilal B. Patel, Michael R.L. Stratford & Peter Wardman. (1993) Targeting radiosensitizers to DNA by minor groove binding: nitroarenes based on netropsin and distamycin. Bioorganic & Medicinal Chemistry Letters 3:8, pages 1697-1702.
Crossref
PETER WARDMAN. 1993. Atmospheric Oxidation and Antioxidants. Atmospheric Oxidation and Antioxidants
101
127
.
David M.L. Goodgame, Christopher J. Page, David J. Williams & Ian J. Stratford. (1992) Metal complexes as radiosensitizers: Cobalt(II), copper(II), rhodium(II) and platinum(II) complexes of 3-(1-imidazoyl)propionic acid and some nitro-substituted derivatives, and the crystal structure and radiosensitizer activity of [CuL2(H2O)]2 · 2H2O, where LH = 3-[1-(4-nitroimidazoyl)]propionic acid. Polyhedron 11:19, pages 2507-2515.
Crossref
David J. Chaplin & Michael R. Horsman. (1992) Tumor blood flow changes induced by chemical modifiers of radiation response. International Journal of Radiation Oncology*Biology*Physics 22:3, pages 459-462.
Crossref
Peter Wardman, Madeleine F. Dennis, Michael R.L. Stratford & John White. (1992) Extracellular: Intracellular and subcellular concentration gradients of thiols. International Journal of Radiation Oncology*Biology*Physics 22:4, pages 751-754.
Crossref
Lloyd D. Skarsgard, David J. Chaplin, Douglas J. Wilson, Mark W. Skwarchuk, Adriana Vinczan & Jiri Kristl. (1992) The effect of hypoxia and low pH on the cytotoxicity of chlorambucil. International Journal of Radiation Oncology*Biology*Physics 22:4, pages 737-741.
Crossref
Alphonse Taghian, Franqoise Lespinasse & Marcell E. Guichard. (1991) Radiosensitization by the combination of etanidazole (SR-2508) and pimonidazole (Ro 03-8799) in human tumor xenografts. International Journal of Radiation Oncology*Biology*Physics 21:6, pages 1535-1540.
Crossref
M. E. Watts & M. Woodcock. (1991) Radiosensitization of Chinese hamster cells by pimonidazole (Ro 03–8799) at low X-ray doses. The British Journal of Radiology 64:766, pages 971-974.
Crossref
Helen B. Stone, V. Kate Hirst, Randolph Cribbs, Yung H. Luu & J. Martin Brown. (1991) A comparison of radiosensitization by etanidazole and pimonidazole in mouse tumors. International Journal of Radiation Oncology*Biology*Physics 20:5, pages 987-995.
Crossref
Peter Wardman. 1991. The Early Effects of Radiation on DNA. The Early Effects of Radiation on DNA
249
264
.
Yoshimitsu Nagao, Shigeki Sano, Masahito Ochiai & Eiichi Fujita. (1990) Biomimetic chemical, and spectroscopic evaluations for the radiosensitizing potential of N1- and N2-substituted derivatives of 3-Nitro-1,2,4-Triazole toward hypoxic cells in the radiotherapy: Remarkably different substitution effect. Tetrahedron 46:9, pages 3211-3232.
Crossref
T. C. Jenkins. 1990. The Chemistry of Antitumour Agents. The Chemistry of Antitumour Agents
342
369
.
William G. Degraff, Angelo Russo, Janet Gamson & James B. Mitchell. (1989) Evaluation of nitroimidazole hypoxic cell radiosensitizers in a human tumor cell line high in intracellular glutathione. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 1021-1024.
Crossref
Michael R.L. Stratford, Madeleine F. Dennis, Margaret E. Watts, Rodeina R. Watfa & Michael Woodcock. (1989) Radiosensitizer-DNA interactions in relation to intracellular uptake. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 1007-1010.
Crossref
J. Martin Brown. (1989) Keynote address: Hypoxic cell radiosensitizers: Where next?. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 987-993.
Crossref
Peter Wardman, Madeleine F. Dennis & John White. (1989) A probe for intracellular concentrations of drugs: Delayed fluorescence from acridine orange. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 935-938.
Crossref
Paul Workman. (1989) Micropharmacokinetics of chemical modifiers. International Journal of Radiation Oncology*Biology*Physics 16:4, pages 897-906.
Crossref
Peter Wardman. (1989) Molecular mechanisms of oxygen and “electron-affinic” radiosensitizers. International Journal of Radiation Oncology*Biology*Physics 16:1, pages 286-287.
Crossref
P. Workman. 1989. Drug Delivery in Cancer Treatment II. Drug Delivery in Cancer Treatment II
79
102
.
H.F.V. Newman, R. Ward, P. Workman & N.M. Bleehen. (1988) The multi-dose clinical tolerance and pharmacokinetics of the combined radiosensitizers, Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International Journal of Radiation Oncology*Biology*Physics 15:5, pages 1073-1083.
Crossref
P. Siem-Jørgensen. (1988) Text slides. The British Journal of Radiology 61:729, pages 861-862.
Crossref
Nicholas Chalmers & Jonathan Best. (1988) A method of weighing an obese, trolley-bound patient. The British Journal of Radiology 61:729, pages 861-861.
Crossref
M. R. L. Stratford, M. F. Dennis, M. E. Watts & R. R. Watfa. (1988) Radiosensitizer–DNA interactions. The British Journal of Radiology 61:729, pages 860-861.
Crossref
H.F.V. Newman, N.M. Bleehen, R. Ward & P. Workman. (1988) Hypoxic cell radiosensitizers in the treatment of high grade gliomas: A new direction using combined Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International Journal of Radiation Oncology*Biology*Physics 15:3, pages 677-684.
Crossref
N. M. Bleehen, M. I. Walton & P. Workman. 1988. Preclinical Hyperthermia. Preclinical Hyperthermia
136
148
.
G. Adams & I. J. Stratford. 1988. Radiobiology in Radiotherapy. Radiobiology in Radiotherapy
153
164
.
M. E. Watts, M. F. Dennis & M. Woodcock. (1987)
Uptake and additivity of the radiosensitising effects of Ro 03–8799 and SR-2508 in mammalian cells
in vitro
. The British Journal of Radiology 60:720, pages 1233-1235.
Crossref
R.J. Hodgkiss, R.W. Middleton, M.R.L. Stratford & R. Del Buono. (1987) Toxicity of 3-nitronaphthalimides to V79 379A Chinese hamster cells. Biochemical Pharmacology 36:9, pages 1483-1487.
Crossref
Peter Wardman. (1987) The mechanism of radiosensitization by electron-affinic compounds. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 30:5-6, pages 423-432.
Crossref
Andrew R.J. Silver, Shona S. Mcneil, Peter O'Neill, Terence C. Jenkins & Israr Ahmed. (1986) Induction of DNA strand breaks by reduced nitroimidazoles. Biochemical Pharmacology 35:22, pages 3923-3928.
Crossref
S. Dische, M. I. Saunders, M. H. Bennett, E. P. Dunphy, C. Des Rochers, M. R. L. Stratford, A. I. Minchinton & P. Wardman. (1986) A comparison of the tumour concentrations obtainable with misonidazole and Ro 03–8799. The British Journal of Radiology 59:705, pages 911-917.
Crossref
M.E. Watts, M.F. Dennis, M.R.L. Stratford & P. Wardman. (1986) Glutathione-reactive nitro compounds as radiosensitizers: Mechanistic and therapeutic implications. International Journal of Radiation Oncology*Biology*Physics 12:7, pages 1135-1138.
Crossref
Hugh F.V. Newman, Norman M. Bleehen & Paul Workman. (1986) A phase I study of the combination of two hypoxic cell radiosensitizers, Ro 03-8799 and SR-2508: Toxicity and pharmacokinetics. International Journal of Radiation Oncology*Biology*Physics 12:7, pages 1113-1116.
Crossref
J.M. Walling, I.J. Stratford, G.E. Adams, A.R.J. Silver, I. Ahmed, T.C. Jenkins & E.M. Fielden. (1986) Studies on the mechanisms of the radiosensitizing and cytotoxic properties of RSU-1069 and its analogues. International Journal of Radiation Oncology*Biology*Physics 12:7, pages 1083-1086.
Crossref
I. Ahmed, T.C. Jenkins, J.M. Walling, I.J. Stratford, P.W. Sheldon, G.E. Adams & E.M. Fielden. (1986) Analogues of RSU-1069: Radiosensitization and toxicity in vitro and in vivo. International Journal of Radiation Oncology*Biology*Physics 12:7, pages 1079-1081.
Crossref
N. Yarlett, N.C. Yarlett & D. Lloyd. (1986) Ferredoxin-dependent reduction of nitroimidazole derivatives in drug-resistant and susceptible strains of trichomonas vaginalis. Biochemical Pharmacology 35:10, pages 1703-1708.
Crossref
M. R. L. Stratford & R. J. Hodgkiss. (1986)
Radioprotection by ascorbate
in vitro
: temperature-dependent uptake
. The British Journal of Radiology 59:697, pages 83-84.
Crossref
G.E. ADAMS & I.J. STRATFORD. 1986. Bioreduction in the Activation of Drugs. Bioreduction in the Activation of Drugs
71
76
.