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International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine Volume 50, 1986 - Issue 6
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Original Article

Differential Radiosensitization of Human Tumour Cells by 3-aminobenzamide and Benzamide: Inhibitors of Poly(ADP-ribosylation)

Peter J. Thraves Department of Radiation Medicine, The Vincent T. Lombardi Cancer Research Center, Georgetown University Medical Center, 3800 Reservoir Road, N.W., Washington, D.C., 20007, U.S.A.
,
Kenneth L. Mossman Department of Radiation Medicine, The Vincent T. Lombardi Cancer Research Center, Georgetown University Medical Center, 3800 Reservoir Road, N.W., Washington, D.C., 20007, U.S.A.
,
Terrence Brennan Department of Radiation Medicine, The Vincent T. Lombardi Cancer Research Center, Georgetown University Medical Center, 3800 Reservoir Road, N.W., Washington, D.C., 20007, U.S.A.
&
Anatoly Dritschilo Department of Radiation Medicine, The Vincent T. Lombardi Cancer Research Center, Georgetown University Medical Center, 3800 Reservoir Road, N.W., Washington, D.C., 20007, U.S.A.
Pages 961-972 | Received 13 Mar 1986, Accepted 15 May 1986, Published online: 03 Jul 2009

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Lloyd R. Kelland & G. Gordon Steel. (1988) Modification of Radiation Dose-rate Sparing Effects in a Human Carcinoma of the Cervix Cell Line by Inhibitors of DNA Repair. International Journal of Radiation Biology 54:2, pages 229-244.
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Qing Wang. (2015) Cancer predisposition genes: molecular mechanisms and clinical impact on personalized cancer care: examples of Lynch and HBOC syndromes. Acta Pharmacologica Sinica 37:2, pages 143-149.
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Joana M. Senra, Brian A. Telfer, Kim E. Cherry, Cian M. McCrudden, David G. Hirst, Mark J. O'Connor, Stephen R. Wedge & Ian J. Stratford. (2011) Inhibition of PARP-1 by Olaparib (AZD2281) Increases the Radiosensitivity of a Lung Tumor Xenograft. Molecular Cancer Therapeutics 10:10, pages 1949-1958.
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C. Powell, C. Mikropoulos, S.B. Kaye, C.M. Nutting, S.A. Bhide, K. Newbold & K.J. Harrington. (2010) Pre-clinical and clinical evaluation of PARP inhibitors as tumour-specific radiosensitisers. Cancer Treatment Reviews 36:7, pages 566-575.
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Vicente Notario, Silvia Mateo-Lozano, Joaquín Villar & Oscar M. Tirado. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling 2859 2871 .
Viatcheslav A Soldatenkov, Irina N Trofimova, Ana Rouzaut, Frank McDermott, Anatoly Dritschilo & Vicente Notario. (2002) Differential regulation of the response to DNA damage in Ewing's sarcoma cells by ETS1 and EWS/FLI-1. Oncogene 21:18, pages 2890-2895.
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Mark P. Mattson, Weiming Fu & Peisu Zhang. 2001. Telomerase, Aging and Disease. Telomerase, Aging and Disease 131 150 .
Viatcheslav A. Soldatenkov & Mark Smulson. (2000) Poly(ADP-ribose) polymerase in DNA damage-response pathway:Implications for radiation oncology. International Journal of Cancer 90:2, pages 59-67.
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Patrick J. Deschavanne & Bernard Fertil. (1996) A review of human cell radiosensitivity in vitro. International Journal of Radiation Oncology*Biology*Physics 34:1, pages 251-266.
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D. Weltin, V. Picard, K. Aupeix, M. Varin, D. Oth, J. Marchal, P. Dufour & P. Bischoff. (1995) Immunosuppressive activities of 6(5h)-phenanthridinone, a new poly(adp-ribose)polymerase inhibitor. International Journal of Immunopharmacology 17:4, pages 265-271.
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Matías A. Avila, Juan A. Velasco, Mark E. Smulson, Anatoly Dritschilo, Rafael Castro & Vicente Notario. (2004) Functional expression of human poly(ADP‐ribose) polymerase in Schizosaccharomyces pombe results in mitotic delay at G 1 , increased mutation rate, and sensitization to radiation . Yeast 10:8, pages 1003-1017.
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W. R. Leopold & Judith S. Sebolt-Leopold. 1992. Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development. Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development 179 196 .
Lloyd R. Kelland & Katia S. Tonkin. (1989) The effect of 3-aminobenzamide in the radiation response of three human cervix carcinoma xenografts. Radiotherapy and Oncology 15:4, pages 363-369.
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N. Chavaudra, M. Halimi, C. Parmentier, N. Gaillard, S. Grinfeld & E.P. Malaise. (1989) The initial slope of human tumor cell survival curves: Its modification by the oxic cell sensitizer β-Arabinofuranosyladenine. International Journal of Radiation Oncology*Biology*Physics 16:5, pages 1267-1271.
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Peter J. Thraves, Kishor Bhatia, Mark E. Smulson & Anatoly Dritschilo. 1989. ADP-Ribose Transfer Reactions. ADP-Ribose Transfer Reactions 520 524 .
F. Darroudi, T. S. B. Zwanenburg, A. T. Natarajan, O. Driessen & A. van Langevelde. 1989. ADP-Ribose Transfer Reactions. ADP-Ribose Transfer Reactions 390 395 .
Sarada C. Prasad, Peter J. Thraves, Jane Boyle & Anatoly Dritschilo. 1989. ADP-Ribose Transfer Reactions. ADP-Ribose Transfer Reactions 94 100 .
Lloyd R. Kelland & G.Gordon Steel. (1988) Inhibition of recovery from damage induced by ionizing radiation in mammalian cells. Radiotherapy and Oncology 13:4, pages 285-299.
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David A. Boothman, Robert Schlegel & Arthur B. Pardee. (1988) Anticarcinogenic potential of DNA-repair modulators. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 202:2, pages 393-411.
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Elisabeth Kjellén, Ronald W. Pero & Per Nilsson. (1988) Comparison of low dose nicotinamide versus benzamide, administered per os, as radiosensitizers in a C3H mammary carcinoma. Radiotherapy and Oncology 12:4, pages 327-331.
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Lloyd R. Kelland, Lynne Burgess & G.Gordon Steel. (1988) Differential radiosensitization by the poly(ADP-ribose) transferase inhibitor 3-aminobenzamide in human tumor cells of varying radiosensitivity. International Journal of Radiation Oncology*Biology*Physics 14:6, pages 1239-1246.
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Arthur B. Pardee, Robert Schlegel & David A. Boothman. 1988. Anticarcinogenesis and Radiation Protection. Anticarcinogenesis and Radiation Protection 431 436 .
Peter J. Thraves, Kenneth L. Mossman, Donnamarie T. Frazier & Anatoly Dritschilo. (1986) Inhibition of potentially lethal radiation damage repair in normal and neoplastic human cells by 3-aminobenzamide: An inhibitor of poly(ADP-ribosylation). International Journal of Radiation Oncology*Biology*Physics 12:8, pages 1541-1545.
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