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Original Article

Structure of Hydroxyl Radical-induced DNA-protein Crosslinks in Calf Thymus Nucleohistone in Vitro

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Pages 445-459 | Received 05 Feb 1988, Accepted 25 Apr 1988, Published online: 03 Jul 2009

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M. Dizdaroglu, E. Coskun & P. Jaruga. (2015) Measurement of oxidatively induced DNA damage and its repair, by mass spectrometric techniques. Free Radical Research 49:5, pages 525-548.
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Miral Dizdaroglu & Pawel Jaruga. (2012) Mechanisms of free radical-induced damage to DNA. Free Radical Research 46:4, pages 382-419.
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M. Dizdaroglu. (1992) Measurement of Radiation-induced Damage to DNA at the Molecular Level. International Journal of Radiation Biology 61:2, pages 175-183.
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Vincent Favaudon. (1989) Radiation-induced Crosslinking between Poly(deoxyadenylic-deoxythymidylic Acid) and Tripeptides Containing Aromatic Residues. International Journal of Radiation Biology 55:3, pages 353-364.
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Arnold GroehlerIVIV, Stefan Kren, Qinglu Li, Maggie Robledo-Villafane, Joshua Schmidt, Mary Garry & Natalia Tretyakova. (2018) Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury. Free Radical Biology and Medicine 120, pages 89-101.
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Miral Dizdaroglu. (2015) Oxidatively induced DNA damage and its repair in cancer. Mutation Research/Reviews in Mutation Research 763, pages 212-245.
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Yuriy Uvaydov, Nicholas E. Geacintov & Vladimir Shafirovich. (2014) Generation of guanine–amino acid cross-links by a free radical combination mechanism. Phys. Chem. Chem. Phys. 16:23, pages 11729-11736.
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N R Jena. (2012) DNA damage by reactive species: Mechanisms, mutation and repair. Journal of Biosciences 37:3, pages 503-517.
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Christopher M. Liebold, Qingxin Lei, William L. Boatright & M. Shah Jahan. (2011) Metastable Radicals and Intrinsic Chemiluminescence from Soy Proteins. Journal of Food Science 76:7, pages C1101-C1107.
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Qingxin Lei, Christopher M. Liebold, William L. Boatright & M. Shah Jahan. (2010) Distribution of Stable Free Radicals among Amino Acids of Isolated Soy Proteins. Journal of Food Science 75:7, pages C633-C640.
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William L. Boatright & M. Shah Jahan. 2010. Chemistry, Texture, and Flavor of Soy. Chemistry, Texture, and Flavor of Soy 3 21 .
Peter Tarábek, Marija Bonifačić & Dieter Beckert. (2007) Oxidation of Cyclic Dipeptides by Photoinduced H-Atom Abstraction. A Laser Flash FT EPR and Optical Spectroscopy Study. The Journal of Physical Chemistry A 111:23, pages 4958-4964.
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Wei‐Qun Shi, Jia Hu, Wei Zhao, Xiao‐Yang Su, Hui Cai, Yu‐Fen Zhao & Yan‐Mei Li. (2006) Identification of radiation‐induced cross‐linking between thymine and tryptophan by electrospray ionization‐mass spectrometry. Journal of Mass Spectrometry 41:9, pages 1205-1211.
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Clemens von Sonntag. 2006. Free-Radical-Induced DNA Damage and Its Repair. Free-Radical-Induced DNA Damage and Its Repair 211 334 .
Sharon Barker, Michael Weinfeld, Jing Zheng, Liang Li & David Murray. (2005) Identification of Mammalian Proteins Cross-linked to DNA by Ionizing Radiation. Journal of Biological Chemistry 280:40, pages 33826-33838.
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Petar M. Mitrasinovic. (2005) Cross-Linking between Thymine and Indolyl Radical:  Possible Mechanisms for Cross-Linking of DNA and Tryptophan-Containing Peptides. Bioconjugate Chemistry 16:3, pages 588-597.
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Thomas A. Shell & Debra L. Mohler. (2005) Selective targeting of DNA for cleavage within DNA–histone assemblies by a spermine–[CpW(CO)3Ph]2 conjugate. Organic & Biomolecular Chemistry 3:17, pages 3091.
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Fuqiang Ban, Maria J. Lundqvist, Russell J. Boyd & Leif A. Eriksson. (2002) Theoretical Studies of the Cross-Linking Mechanisms between Cytosine and Tyrosine. Journal of the American Chemical Society 124:11, pages 2753-2761.
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Gary M. Williams & Alan M. Jeffrey. (2000) Oxidative DNA Damage: Endogenous and Chemically Induced. Regulatory Toxicology and Pharmacology 32:3, pages 283-292.
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Michael B. Goshe, Yong Hong Chen & Vernon E. Anderson. (2000) Identification of the Sites of Hydroxyl Radical Reaction with Peptides by Hydrogen/Deuterium Exchange:  Prevalence of Reactions with the Side Chains. Biochemistry 39:7, pages 1761-1770.
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Miral Dizdaroglu. 1999. Advances in DNA Damage and Repair. Advances in DNA Damage and Repair 67 87 .
Byung YuMiral Dizdaroglu. 1998. Methods in Aging Research. Methods in Aging Research 607 620 .
Syota Morimoto, Hiroshi Hatta, Shin-ichi Fujita, Tomochika Matsuyama, Tôru Ueno & Sei-ichi Nishimoto. (1998) Hydroxyl radical-induced cross-linking of thymine and lysine: Identification of the primary structure and mechanism. Bioorganic & Medicinal Chemistry Letters 8:7, pages 865-870.
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Jochen J. Brocks, Frank M. Welle, Hans-Dieter Beckhaus & Christoph Rüchardt. (1997) Are α-centered peptide radicals stabilized by a capto-dative effect?. Tetrahedron Letters 38:44, pages 7721-7724.
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Steven G. Swarts, George S. Smith, Lan Miao & Kenneth T. Wheeler. (1996) Effects of formic acid hydrolysis on the quantitative analysis of radiation-induced DNA base damage products assayed by gas chromatography/mass spectrometry. Radiation and Environmental Biophysics 35:1, pages 41-53.
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Steven A. Altman, Tomasz H. Zastawny, Lisa Randers-Eichhorn, Marco A. Cacciuttolo, Steven A. Akman, Miral Dizdaroglu & Govind Rao. (1995) Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions. Free Radical Biology and Medicine 19:6, pages 897-902.
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Shinya Toyokuni, Toshiaki Mori, Hiroshi Hiai & Miral Dizdaroglu. (2006) Treatment of wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes dna‐protein cross‐linking between thymine and tyrosine in their renal chromatin. International Journal of Cancer 62:3, pages 309-313.
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Mary S. Weir, David L. Springer, Brian D. Thrall, Alfred F. Fuciarelli & Charles G. Edmonds. 1994. 115 122 .
Miral Dizdaroglu. 1994. Oxygen Radicals in Biological Systems Part D. Oxygen Radicals in Biological Systems Part D 3 16 .
Song Mao Chiu, Liang Yan Xue, Libby R. Friedman & Nancy L. Oleinick. (2002) Copper ion-mediated sensitization of nuclear matrix attachment sites to ionizing radiation. Biochemistry 32:24, pages 6214-6219.
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David Becker & Michael D. Sevilla. 1993. Advances in Radiation Biology - DNA and Chromatin Damage Caused by Radiation. Advances in Radiation Biology - DNA and Chromatin Damage Caused by Radiation 121 180 .
Miral Dizdaroglu. (1992) Oxidative damage to DNA in mammalian chromatin. Mutation Research/DNAging 275:3-6, pages 331-342.
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James A. McCloskey & Pamela F. Crain. (1992) Progress in mass spectrometry of nucleic acid constituents: analysis of xenobiotic modifications and measurements at high mass. International Journal of Mass Spectrometry and Ion Processes 118-119, pages 593-615.
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Ryszard Olinski, Zeena Nackerdien & Miral Dizdaroglu. (1992) DNA-protein cross-linking between thymine and tyrosine in chromatin of ?-irradiated or H2O2-treated cultured human cells. Archives of Biochemistry and Biophysics 297:1, pages 139-143.
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James A. McCloskey & Pamela F. Crain. 1992. Advances in Mass Spectrometry. Advances in Mass Spectrometry 593 615 .
Zeena Nackerdien, Govind Rao, Marco A. Cacciuttolo, Ewa Gajewski & Miral Dizdaroglu. (2002) Chemical nature of DNA-protein cross-links produced in mammalian chromatin by hydrogen peroxide in the presence of iron or copper ions. Biochemistry 30:20, pages 4873-4879.
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Barry Halliwell & Okezie I. Aruoma. (2001) DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems. FEBS Letters 281:1-2, pages 9-19.
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Miral Dizdaroglu. (1991) Chemical determination of free radical-induced damage to DNA. Free Radical Biology and Medicine 10:3-4, pages 225-242.
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A. F. Fuciarelli, W. F. Blakely, B. J. Wegher & M. Dizdaroglu. 1991. The Early Effects of Radiation on DNA. The Early Effects of Radiation on DNA 405 408 .
Ewa Gajewski, Govind Rao, Zeena Nackerdien & Miral Dizdaroglu. (2002) Modification of DNA bases in mammalian chromatin by radiation-generated free radicals. Biochemistry 29:34, pages 7876-7882.
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Ewa Gajewski & Miral Dizdaroglu. (2002) Hydroxyl radical induced cross-linking of cytosine and tyrosine in nucleohistone. Biochemistry 29:4, pages 977-980.
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Miral Dizdaroglu. 1990. Mass Spectrometry. Mass Spectrometry 842 857 .
Miral Dizdaroglu & Ewa Gajewski. 1990. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants 530 544 .

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