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Original Article

Comparative Human Cellular Radiosensitivity: I. The Effect of SV40 Transformation and Immortalisation on the Gamma-irradiation Survival of Skin Derived Fibroblasts from Normal Individuals and from Ataxia-telangiectasia Patients and Heterozygotes

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Pages 911-928 | Received 06 Apr 1988, Accepted 25 Jul 1988, Published online: 03 Jul 2009

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Shujuan Chen, Gang Wang, G.Mike Makrigiorgos & Brendan D Price. (2004) Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells. Biochemical and Biophysical Research Communications 317:4, pages 1037-1044.
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Mark O'Driscoll, Victor L. Ruiz-Perez, C. Geoffrey Woods, Penny A. Jeggo & Judith A. Goodship. (2003) A splicing mutation affecting expression of ataxia–telangiectasia and Rad3–related protein (ATR) results in Seckel syndrome. Nature Genetics 33:4, pages 497-501.
Crossref
Y. DaiB. KyselaL. A. HanakahiK. ManolisE. RiballoM. StummT. O. HarvilleS. C. WestM. A. OettingerP. A. Jeggo. (2003) Nonhomologous end joining and V(D)J recombination require an additional factor. Proceedings of the National Academy of Sciences 100:5, pages 2462-2467.
Crossref
George Martin, Fuki Hisama & Sherman WeissmanM Stephen Meyn. 2003. Chromosomal Instability and Aging. Chromosomal Instability and Aging.
Pierre-Marie Girard, Enriqueta Riballo, Adrian C Begg, Alastair Waugh & Penny A Jeggo. (2002) Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene 21:27, pages 4191-4199.
Crossref
Mark O'Driscoll, Karen M. Cerosaletti, Pierre-M Girard, Yan Dai, Markus Stumm, Boris Kysela, Betsy Hirsch, Andrew Gennery, Susan E. Palmer, Jörg Seidel, Richard A. Gatti, Raymonda Varon, Marjorie A. Oettinger, Heidemarie Neitzel, Penny A. Jeggo & Patrick Concannon. (2001) DNA Ligase IV Mutations Identified in Patients Exhibiting Developmental Delay and Immunodeficiency. Molecular Cell 8:6, pages 1175-1185.
Crossref
Enriqueta Riballo, Aidan J. Doherty, Yan Dai, Thomas Stiff, Marjorie A. Oettinger, Penny A. Jeggo & Boris Kysela. (2001) Cellular and Biochemical Impact of a Mutation in DNA Ligase IV Conferring Clinical Radiosensitivity. Journal of Biological Chemistry 276:33, pages 31124-31132.
Crossref
Yiola Marcou, Andrew D'Andrea, Penelope A Jeggo & Piers N Plowman. (2001) Normal cellular radiosensitivity in an adult Fanconi anaemia patient with marked clinical radiosensitivity. Radiotherapy and Oncology 60:1, pages 75-79.
Crossref
Maria Kraakman-van der Zwet, Wilhelmina J.I. Overkamp, Nicolaas G.J. Jaspers, Adayapalam T. Natarajan, Paul H.M. Lohman & Małgorzata Z. Zdzienicka. (2001) Complementation of chromosomal aberrations in AT/NBS hybrids: inadequacy of RDS as an endpoint in complementation studies with immortal NBS cells. Mutation Research/DNA Repair 485:3, pages 177-185.
Crossref
Marcela Savoldi‐Barbosa & Elza T. Sakamoto‐Hojo. (2001) Influence of interferon‐γ on radiation‐induced apoptosis in normal and ataxia‐telangiectasia fibroblast cell lines. Teratogenesis, Carcinogenesis, and Mutagenesis 21:6, pages 417-429.
Crossref
Theo van Laar, Theo Schouten, Alex J. van der Eb & Carrol Terleth. (2001) Induction of the SAPK activator MIG‐6 by the alkylating agent methyl methanesulfonate . Molecular Carcinogenesis 31:2, pages 63-67.
Crossref
Paul Bryan Rogers, Piers Nicholas Plowman, Sarah Jane Harris & Colin Francis Arlett. (2000) Four radiation hypersensitivity cases and their implications for clinical radiotherapy. Radiotherapy and Oncology 57:2, pages 143-154.
Crossref
Corinne Petit-Frère, Emily Capulas, Debbie A. Lyon, Christopher J. Norbury, Jillian E. Lowe, Peter H. Clingen, Enriqueta Riballo, Michael H. L. Green & Colin F. Arlett. (2000) Apoptosis and cytokine release induced by ionizing or ultraviolet B radiation in primary and immortalized human keratinocytes. Carcinogenesis 21:6, pages 1087-1095.
Crossref
Theo van Laar, Theo Schouten, Esther Hoogervorst, Marga van Eck, Alex J. van der Eb & Carrol Terleth. (2000) The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway . FEBS Letters 469:1, pages 123-131.
Crossref
John N. DeSimone, Hana Dolezalova, J. Leslie Redpath & Eric J. Stanbridge. (2000) Prolonged Cell Cycle Arrest in Irradiated Human Diploid Skin Fibroblasts: The Role of Nutrient Deprivation. Radiation Research 153:2, pages 131-143.
Crossref
M. Stephen Meyn. (2001) Ataxia‐telangiectasia, cancer and the pathobiology of the ATM gene . Clinical Genetics 55:5, pages 289-304.
Crossref
Maria Kraakman-van der Zwet, Wilhelmina J.I Overkamp, Anna A Friedl, Binie Klein, Gerald W.C.T Verhaegh, Nicolaas G.J Jaspers, Alina T Midro, Friederike Eckardt-Schupp, Paul H.M Lohman & Małgorzata Z Zdzienicka. (1999) Immortalization and characterization of Nijmegen Breakage Syndrome fibroblasts. Mutation Research/DNA Repair 434:1, pages 17-27.
Crossref
R.I. Mackay & J.H. Hendry. (1999) The modelled benefits of individualizing radiotherapy patients’ dose using cellular radiosensitivity assays with inherent variability. Radiotherapy and Oncology 50:1, pages 67-75.
Crossref
Susan Varghese, Rupert K. Schmidt-Ullrich, Anatoly Dritschilo & Mira Jung. (1999) Enhanced radiation late effects and cellular radiation sensitivity in an ATM heterozygous breast cancer patient. Radiation Oncology Investigations 7:4, pages 231-237.
Crossref
Marie‐Hélène Gaugler, Claire Squiban, Marie Claraz, Karin Schweitzer, Babette Weksler, Patrick Gourmelon & Anne Van der Meeren. (2008) Characterization of the response of human bone marrow endothelial cells to in vitro irradiation . British Journal of Haematology 103:4, pages 980-989.
Crossref
Youichi Odagiri, Hiroyuki Uchida & Satomi Shibazaki. (1997) Interindividual variation in cytogenetic response to X-ray and colchicine measured with the cytokinesis-block micronucleus assay. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 381:1, pages 1-13.
Crossref
J.A. Hanson, E.M. Parry, A.R. Gibbs, J.B. Court, M.A.H. Pour-Faizi, I.J. Kerby & E.A. Bean. (1997) Characterization of Highly Radiosensitive Cell Lines from a Human Ovarian Small-Cell Cancer. Gynecologic Oncology 67:2, pages 147-153.
Crossref
Murray A Francis, Paramjeet S Bagga, Raghbir S Athwal & Andrew J Rainbow. (1997) Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair. Mutation Research/DNA Repair 385:1, pages 59-74.
Crossref
Carl N Sprung, Tracy M Bryan, Roger R Reddel & John P Murnane. (1997) Normal telomere maintenance in immortal ataxia telangiectasia cell lines. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 379:2, pages 177-184.
Crossref
W. Budach. (1997) Genetische Prädisposition und Strahlenempfindlichkeit von TumorenGenetic predisposition and tumor radiation sensitivity. Strahlentherapie und Onkologie 173:9, pages 469-479.
Crossref
Volker Rudat, Andreas Dietz, Christian Conradt, Klaus-Josef Weber & Michael Flentje. (1997) In vitro radiosensitivity of primary human fibroblasts. Lack of correlation with acute radiation toxicity in patients with head and neck cancer. Radiotherapy and Oncology 43:2, pages 181-188.
Crossref
Masanobu HAYASHI, Kazuhisa UEHARA, Rikio KIRISAWA, Daiji ENDOH, Soichiro ARAI & Toyo OKUI. (1997) Abnormal G1 Arrest in the Cell Lines from LEC Strain Rats after X-Irradiation.. Journal of Veterinary Medical Science 59:9, pages 769-773.
Crossref
Michael H.L Green, Adam J Marcovitch, Susan A Harcourt, Jillian E Lowe, Irene C Green & Colin F Arlett. (1997) Hypersensitivity of ataxia-telangiectasia fibroblasts to a nitric oxide donor. Free Radical Biology and Medicine 22:1-2, pages 343-347.
Crossref
Anthony R.M. Sproston, Catharine M.L. West & Jolyon H. Hendry. (1997) Cellular radiosensitivity in human severe-combined-immunodeficiency (SCID) syndromes. Radiotherapy and Oncology 42:1, pages 53-57.
Crossref
M. S. Meyn. 1997. Genetic Instability and Tumorigenesis. Genetic Instability and Tumorigenesis 71 148 .
Simon Attard-Montalto, Vaskar Saha, Judith Kingston, Nicholas Plowman, Malcolm Taylor, Colin Arlett, Bryn Bridges & Osborn Eden. (1996) Increased radiosensitivity in a child with T-cell non-Hodgkin's lymphoma. Medical and Pediatric Oncology 27:6, pages 565-570.
Crossref
Robert G. Bristow, Samuel Benchimol & Richard P. Hill. (1996) The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiotherapy and Oncology 40:3, pages 197-223.
Crossref
Masanobu Hayashi, Kumiko Ishimori, Akihiko Maeda, Tomomasa Watanabe, Soichiro Arai & Toyo Okui. (1996) Radioresistant DNA synthesis in fibroblast cell lines derived from LEC strain rats. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 352:1-2, pages 117-121.
Crossref
Patrick J. Deschavanne & Bernard Fertil. (1996) A review of human cell radiosensitivity in vitro. International Journal of Radiation Oncology*Biology*Physics 34:1, pages 251-266.
Crossref
Mira JungYin ZhangSung LeeAnatoly Dritschilo. (1995) Correction of Radiation Sensitivity in Ataxia Telangiectasia Cells by a Truncated IκB-α. Science 268:5217, pages 1619-1621.
Crossref
John P. Murnane. (1995) Cell cycle regulation in response to DNA damage in mammalian cells: A historical perspective. Cancer and Metastasis Reviews 14:1, pages 17-29.
Crossref
Michael Baumann. 1995. Late Sequelae in Oncology. Late Sequelae in Oncology 3 12 .
Mira Jung, Alexandre Dimtchev, Yin Zhang & Anatoly Dritschilo. (2007) Identification of gene(s) involved in carcinogenic progression of ataxia telangiectasia cells. Radiation Oncology Investigations 3:6, pages 272-278.
Crossref
A Di Leonardo, S P Linke, K Clarkin & G M Wahl. (1994) DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.. Genes & Development 8:21, pages 2540-2551.
Crossref
Reinhard Wurm, Neil G. Burnet, Nisha Duggal, John R. Yarnold & John H. Peacock. (1994) Cellular radiosensitivity and dna damage in primary human fibroblasts. International Journal of Radiation Oncology*Biology*Physics 30:3, pages 625-633.
Crossref
Michael H.L. Green, Jillian E. Lowe, Alastair P.W. Waugh, Kay E. Aldridge, Jane Cole & Colin F. Arlett. (1994) Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells. Mutation Research/DNAging 316:2, pages 91-102.
Crossref
Michael H.L. Green, Alastair P.W. Waugh, Jillian E. Lowe, Susan A. Harcourt, Jane Cole & Colin F. Arlett. (1994) Effect of deoxyribonucleosides on the hypersensitivity of human peripheral blood lymphocytes to UV-B and UV-C irradiation. Mutation Research/DNA Repair 315:1, pages 25-32.
Crossref
Mira Oh Jung, Yin Zhang, Zahra Salehi, Francis Kern & Anatoly Dritschilo. (2006) Modification of ataxia telangiectasia cellular radiation sensitivity and resistant dna synthesis by transformation with episomally maintained vectors. Radiation Oncology Investigations 2:6, pages 257-263.
Crossref
John P. Murnane & Jeffrey L. Schwartz. (1993) Cell checkpoint and radiosensitivity. Nature 365:6441, pages 22-22.
Crossref
Simon Powell, Stephen Whitaker, John Peacock & Tevor McMillan. (1993) Ataxia telangiectasia: An investigation of the repair defect in the cell line AT5BIVA by plasmid reconstitution. Mutation Research/DNA Repair 294:1, pages 9-20.
Crossref
Antony M. Carr, Michael H. L. Green & Alan R. Lehmann. (1992) Checkpoint policing by p53. Nature 359:6395, pages 486-486.
Crossref
Christopher N. Parris & Kenneth H. Kraemer. (1992) Ultraviolet mutagenesis in human lymphocytes: The effect of cellular transformation. Experimental Cell Research 201:2, pages 462-469.
Crossref
John K. Wiencke, Diane W. Wara, John B. Little & Karl T. Kelsey. (1992) Heterogeneity in the clastogenic response to X-rays in lymphocytes from ataxia-telangiectasia heterozygotes and controls. Cancer Causes and Control 3:3, pages 237-245.
Crossref
L. Chessa, P. Petrinelli, A. Antonelli, M. Fiorlli, R. Elli, L. Marcucci, A. Federico & E. Gandini. (2005) Heterogeneity in ataxia‐telangiectasia: Classical phenotype associated with intermediate cellular radiosensitivity. American Journal of Medical Genetics 42:5, pages 741-746.
Crossref
C.F. Arlett. 1992. Effects of Low Dose and Low Dose Rate Radiation. Effects of Low Dose and Low Dose Rate Radiation 273 292 .
John Thacker. 1992. Effects of Low Dose and Low Dose Rate Radiation. Effects of Low Dose and Low Dose Rate Radiation 77 124 .
E.P. MALAISE, PATRICK J. DESCHAVANNE & BERNARD FERTIL. 1992. Relative Radiation Sensitivities of Human Organ Systems, Part III. Relative Radiation Sensitivities of Human Organ Systems, Part III 37 70 .
Anna Antonelli, Raffaella Elli, Liana Marcucci, Roberto Bosi, Donatella Kobal & Paola Petrinelli. (1991) Human cells (normal and ataxia telangiectasia) transfected with pR plasmid are hypersensitive to DNA strand-breaking agents. Mutation Research/DNA Repair 255:1, pages 11-18.
Crossref
L. V. Mayne. 1992. Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport. Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport 347 354 .
C.N. Parris, J.R.W. Masters & M.H.L. Green. (1990) pSV3neo transfection and radiosensitivity of human cancer cell lines. Cancer Letters 55:2, pages 171-175.
Crossref
JULIA A. EWTON, ANNE KOBZA BLACK, C.F. ARLETT & JANE COLE. (1990) Radiobiological studies in the naevoid basal cell carcinoma syndrome. British Journal of Dermatology 123:5, pages 573-580.
Crossref
P. N. Plowman, B. A. Bridges, C. F. Arlett, A. Hinney & J. E. Kingston. (1990) An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia. The British Journal of Radiology 63:752, pages 624-628.
Crossref
Wayne P. Wahls & Peter D. Moore. (1990) Relative frequencies of homologous recombination between plasmids introduced into DNA repair-deficient and other mammalian somatic cell lines. Somatic Cell and Molecular Genetics 16:4, pages 321-329.
Crossref
N A Brown, G A Shun-Shin, P Lewis, W A Cramp, C Arlett, J Cole, A P Waugh & G Stephens. (1989) Relationship of cataract to radiation sensitivity.. British Journal of Ophthalmology 73:12, pages 955-959.
Crossref
S.W. Dean, L. Kincla, H.R. Sykes, A.R. Lehmann & I.A. Wise. (1989) Instability of extrachromosomal cosmid DNA in SV40-transformed human (ataxia-telangiectasia) cells. Experimental Cell Research 183:2, pages 473-483.
Crossref
John Thacker. (2005) Inherited sensitivity to X‐rays in man. BioEssays 11:2-3, pages 58-62.
Crossref

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