Advanced search
Publication Cover
International Journal of Radiation Biology Volume 62, 1992 - Issue 4
Submit an article Journal homepage
8
Views
20
CrossRef citations to date
0
Altmetric
Original Article

Effects of Trypanothione on the Biological Activity of Irradiated Transforming DNA

S. Awad Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA
,
G.B. Henderson Laboratory of Medical Biochemistry, Rockefeller University, New York, NY, 10021, USA
,
A. Cerami The Picower Institute for Medical Research, 350 Community Drive, Manhasset, NY, 11030, USA
&
K.D. Held Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA
Pages 401-407 | Received 28 Oct 1991, Accepted 18 Mar 1992, Published online: 03 Jul 2009

Citations (20)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Hossein Mozdarani & Mahdieh Salimi. (2006) Numerical chromosome abnormalities in 8-cell embryos generated from γ-irradiated male mice in the absence and presence of vitamin E. International Journal of Radiation Biology 82:11, pages 817-822.
Read now
J. Gutierrez Correa & A. O. M. Stoppani. (1993) Inactivation of Lipoamide Dehydrogenase by Cobalt(II) and Iron(II) Fenton Systems: Effect of Metal Chelators, Thiol Compounds and Adenine Nucleotides. Free Radical Research Communications 19:5, pages 303-314.
Read now

Articles from other publishers (18)

Vahab Ali, Sachidananda Behera, Afreen Nawaz, Asif Equbal & Krishna Pandey. 2022. 75 155 .
Marcelo A. Comini. 2022. Redox Chemistry and Biology of Thiols. Redox Chemistry and Biology of Thiols 555 584 .
Héctor Lucio, Miguel A. Toro, María‐José Camarasa, Sonsoles Velázquez, Federico Gago & Antonio Jiménez‐Ruiz. (2020) Pseudoirreversible slow‐binding inhibition of trypanothione reductase by a protein–protein interaction disruptor. British Journal of Pharmacology 177:22, pages 5163-5176.
Crossref
Alan Talevi, Carolina Carrillo & Marcelo Comini. (2019) The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies. Current Medicinal Chemistry 26:36, pages 6614-6635.
Crossref
Jason Lin, Bing-Yu Chiang, Chi-Chi Chou, Tzu-Chieh Chen, Yi-Ju Chen, Yu-Ju Chen & Chun-Hung Lin. (2015) Glutathionylspermidine in the Modification of Protein SH Groups: The Enzymology and Its Application to Study Protein Glutathionylation. Molecules 20:1, pages 1452-1474.
Crossref
Zohreh Noaparast & Seyed Jalal Hosseinimehr. (2013) Radioprotective agents for the prevention of side effects induced by radioiodine-131 therapy. Future Oncology 9:8, pages 1145-1159.
Crossref
Koen Van LaerChris J. HamiltonJoris Messens. (2013) Low-Molecular-Weight Thiols in Thiol–Disulfide Exchange. Antioxidants & Redox Signaling 18:13, pages 1642-1653.
Crossref
Marcelo A. Comini & Leopold Flohé. 2013. Trypanosomatid Diseases. Trypanosomatid Diseases 167 199 .
Joris Messens, Nicolas Rouhier & Jean-François Collet. 2013. Oxidative Stress and Redox Regulation. Oxidative Stress and Redox Regulation 59 84 .
Kadia Y. Mullings, Nicole Sukdeo, Uthaiwan Suttisansanee, Yanhong Ran & John F. Honek. (2012) Ni2+-activated glyoxalase I from Escherichia coli: Substrate specificity, kinetic isotope effects and evolution within the βαβββ superfamily. Journal of Inorganic Biochemistry 108, pages 133-140.
Crossref
Matthew P. Fitzgerald, Joshua M. Madsen, Mitchell C. Coleman, Melissa L. T. Teoh, Scott G. Westphal, Douglas R. Spitz, Rafael Radi & Frederick E. Domann. (2010) Transgenic Biosynthesis of Trypanothione Protects Escherichia coli from Radiation-Induced Toxicity. Radiation Research 174:3, pages 290-296.
Crossref
R. Luise Krauth-Siegel & Marcelo A. Comini. (2008) Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism. Biochimica et Biophysica Acta (BBA) - General Subjects 1780:11, pages 1236-1248.
Crossref
I. B. Mosse & P. M. Marozik. 2008. Simulation and Assessment of Chemical Processes in a Multiphase Environment. Simulation and Assessment of Chemical Processes in a Multiphase Environment 409 433 .
Luise R. Krauth-Siegel, Marcelo A. Comini & Tanja Schlecker. 2007. Peroxiredoxin Systems. Peroxiredoxin Systems 231 251 .
Juan Diego Maya .Antonio Morello .. (2005) Inhibition of Glutathione Synthesis as a Potential Therapeutic Strategy Against Chagas’ Disease. Journal of Biological Sciences 5:6, pages 847-854.
Crossref
C. El Hanine Lmoumène, D. Conte, J.-P. Jacquot & C. Houée-Levin. (2000) Redox Properties of Protein Disulfide Bond in Oxidized Thioredoxin and Lysozyme:  A Pulse Radiolysis Study. Biochemistry 39:31, pages 9295-9301.
Crossref
Emmanuel Tetaud, Faouzi Manai, Michael P. Barrett, Kari Nadeau, Christopher T. Walsh & Alan H. Fairlamb. (1998) Cloning and Characterization of the Two Enzymes Responsible for Trypanothione Biosynthesis in Crithidia fasciculata. Journal of Biological Chemistry 273:31, pages 19383-19390.
Crossref
John M. KELLY, Martin C. TAYLOR, Keith SMITH, Karl J. HUNTER & Alan H. FAIRLAMB. (2005) Phenotype of recombinant Leishmania donovani and Trypanosoma cruzi which over‐express trypanothione reductase . European Journal of Biochemistry 218:1, pages 29-37.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.