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Original Article

Effect of Multiple Irradiation with Low Doses of Gamma-rays on Morphological Transformation and Growth Ability of Human Embryo Cells in Vitro

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Pages 711-718 | Received 15 Nov 1991, Accepted 26 Apr 1992, Published online: 03 Jul 2009

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Suresh I.S. Rattan. 2019. The Science of Hormesis in Health and Longevity. The Science of Hormesis in Health and Longevity 201 212 .
Suresh I.S. Rattan. 2019. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Shinko KobashigawaGenro Kashino, Keiji Suzuki, Shunichi Yamashita & Hiromu Mori. (2015) Ionizing Radiation-Induced Cell Death Is Partly Caused by Increase of Mitochondrial Reactive Oxygen Species in Normal Human Fibroblast Cells. Radiation Research 183:4, pages 455.
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Shinko Kobashigawa, Genro Kashino, Hiromu Mori & Masami Watanabe. (2015) Relief of delayed oxidative stress by ascorbic acid can suppress radiation-induced cellular senescence in mammalian fibroblast cells. Mechanisms of Ageing and Development 146-148, pages 65-71.
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Satoshi Takeshita, Naoki Matsuda, Seiji Kodama, Keiji Suzuki & Masami Watanabe. (2013) In Vitro Thermal Effects on Embryonic Cells of Endangered Hawksbill Turtle Eretmochelys imbricata . Zoological Science 30:12, pages 1038-1043.
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Takuya OKADA, Genro KASHINO, Hideki NISHIURA, Keizo TANO & Masami WATANABE. (2012) Micronuclei Formation Induced by X-ray Irradiation Does Not Always Result from DNA Double-strand Breaks. Journal of Radiation Research 53:1, pages 93-100.
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Yasuyoshi OKA, Motohiro YAMAUCHI, Masatoshi SUZUKI, Shunichi YAMASHITA & Keiji SUZUKI. (2011) Persistence and Dynamics of DNA Damage Signal Amplification Determined by Microcolony Formation and Live-cell Imaging. Journal of Radiation Research 52:6, pages 766-774.
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Suresh I. S. Rattan & Dino Demirovic. 2010. Hormesis. Hormesis 153 175 .
Keiji Suzuki, Genro Kashino, Seiji Kodama & Masami Watanabe. (2009) Long-term persistence of X-ray-induced genomic instability in quiescent normal human diploid cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 671:1-2, pages 33-39.
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Hanako YOSHII & Masami WATANABE. (2009) Intervention of Oxygen-control Ability to Radiation Sensitivity, Cell Aging and Cell Transformation. Journal of Radiation Research 50:2, pages 127-137.
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Suresh I.S. Rattan. (2008) Hormesis in aging. Ageing Research Reviews 7:1, pages 63-78.
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Fred A. MettlerJr.Jr. & Arthur C. Upton. 2008. Medical Effects of Ionizing Radiation. Medical Effects of Ionizing Radiation 473 476 .
Miwa Horikawa-Miura, Naoki Matsuda, Masahiro Yoshida, Yutaka Okumura, Toshio Mori & Masami Watanabe. (2007) The Greater Lethality of UVB Radiation to Cultured Human Cells is Associated with the Specific Activation of a DNA Damage-Independent Signaling Pathway. Radiation Research 167:6, pages 655-662.
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Nobuyuki Hamada, Giuseppe Schettino, Genro Kashino, Mita Vaid, Keiji Suzuki, Seiji Kodama, Boris Vojnovic, Melvyn Folkard, Masami Watanabe, Barry D. Michael & Kevin M. Prise. (2006) Histone H2AX Phosphorylation in Normal Human Cells Irradiated with Focused Ultrasoft X Rays: Evidence for Chromatin Movement during Repair. Radiation Research 166:1, pages 31-38.
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Masatoshi Suzuki, Keiji Suzuki, Seiji Kodama & Masami Watanabe. (2006) Phosphorylated Histone H2AX Foci Persist on Rejoined Mitotic Chromosomes in Normal Human Diploid Cells Exposed to Ionizing Radiation. Radiation Research 165:3, pages 269-276.
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Masao Suzuki, Chizuru Tsuruoka, Tatsuaki Kanai, Takeshi Kato, Fumio Yatagai & Masami Watanabe. (2006) Cellular and molecular effects for mutation induction in normal human cells irradiated with accelerated neon ions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 594:1-2, pages 86-92.
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Masatoshi Suzuki, Keiji Suzuki, Seiji Kodama & Masami Watanabe. (2006) Interstitial chromatin alteration causes persistent p53 activation involved in the radiation-induced senescence-like growth arrest. Biochemical and Biophysical Research Communications 340:1, pages 145-150.
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M. Suzuki, C. Tsuruoka, Y. Uchihori, S. Ebisawa, H. Yasuda & K. Fujitaka. (2005) Reduction in Life Span of Normal Human Fibroblasts Exposed to Very Low-Dose-Rate Charged Particles. Radiation Research 164:4, pages 505-508.
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Motohiro Yamauchi, Keiji Suzuki, Seiji Kodama & Masami Watanabe. (2005) Abnormal stability of wild-type p53 protein in a human lung carcinoma cell line. Biochemical and Biophysical Research Communications 330:2, pages 483-488.
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Kumio Okaichi, Miwa IDE, Aya Usui & Yutaka Okumura. (2004) Hypergravity Induces Phosphorylation of p53 at Serine 15, but not an Expression of p53-downstream Genes. Journal of Radiation Research 45:3, pages 399-403.
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Masao S. Sasaki. (2003) Radioadaptive response and genomic instability: a phenotypic dichotomy of genome–environment interaction. International Congress Series 1258, pages 11-19.
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Masao Suzuki, Chizuru Tsuruoka, Tatsuaki Kanai, Takeshi Kato, Fumio Yatagai & Masami Watanabe. (2003) Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells.. Biological Sciences in Space 17:4, pages 302-306.
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Masao Suzuki, Hiroshi Yasuda, Ryonfa Lee, Chisa Ohira, Hideyuki Majima, Yoko Yamaguchi, Chizuru Yamaguchi & Kazunobu Fujitaka. (2002) Cellular response in normal human cells exposed to chronically low-dose radiation in heavy-ion radiation field. International Congress Series 1236, pages 323-326.
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Masami Watanabe, Keiji Suzuki & Seiji Kodama. (2002) Specific gene expression by extremely low-dose ionizing radiation which related to enhance proliferation of normal human diploid cells. International Congress Series 1236, pages 237-239.
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Mana Miyakoda, Keiji Suzuki, Seiji Kodama & Masami Watanabe. (2002) Activation of ATM and phosphorylation of p53 by heat shock. Oncogene 21:7, pages 1090-1096.
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Seiji Kodama, Isao Mori, Kanaklata Roy, Zhi Yang, Keiji Suzuki & Masami Watanabe. (2001) Culture Condition-Dependent Senescence-Like Growth Arrest and Immortalization in Rodent Embryo Cells. Radiation Research 155:1, pages 254-262.
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Keiji Suzuki, Isao Mori, Yukiko Nakayama, Mana Miyakoda, Seiji Kodama & Masami Watanabe. (2001) Radiation-Induced Senescence-like Growth Arrest Requires TP53 Function but not Telomere Shortening. Radiation Research 155:1, pages 248-253.
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Naoki Matsuda, Miwa Horikawa, Li-Hong Wang, Masahiro Yoshida, Kumio Okaichi, Yutaka Okumura & Masami Watanabe. (2007) Differential Activation of ERK 1/2 and JNK in Normal Human Fibroblast-like Cells in Response to UVC Radiation Under Different Oxygen Tensions ¶. Photochemistry and Photobiology 72:3, pages 334-339.
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Jagadish C. Ghosh, Yuko Izumida, Keiji Suzuki, Seiji Kodama & Masami Watanabe. (2000) Dose-Dependent Biphasic Accumulation of TP53 Protein in Normal Human Embryo Cells after X Irradiation. Radiation Research 153:3, pages 305-311.
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Naoki Matsuda, Miwa Horikawa, Li-Hong Wang, Masahiro Yoshida, Kumio Okaichi, Yutaka Okumura & Masami Watanabe. (2000) Differential Activation of ERK 1/2 and JNK in Normal Human Fibroblast-like Cells in Response to UVC Radiation Under Different Oxygen Tensions¶. Photochemistry and Photobiology 72:3, pages 334.
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Keiji Suzuki, Seiji Kodama & Masami Watanabe. (1999) Recruitment of ATM Protein to Double Strand DNA Irradiated with Ionizing Radiation. Journal of Biological Chemistry 274:36, pages 25571-25575.
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M Suzuki, Y Kase, T Kanai & K Ando. (1998) Correlation between cell death and induction of non-rejoining PCC breaks by carbon-ion beams. Advances in Space Research 22:4, pages 561-568.
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Takeki Tsutsui, Yuriko Tanaka, Yuko Matsudo, Koko Hasegawa, Takafumi Fujino, Seiji Kodama & J. Carl Barrett. (1997) Extended lifespan and immortalization of human fibroblasts induced by x-ray irradiation. Molecular Carcinogenesis 18:1, pages 7-18.
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M. Suzuki, M. Watanabe, T. Kanai, Y. Kase, F. Yatagai, T. Kato & S. Matsubara. (1996) Let dependence of cell death, mutation induction and chromatin damage in human cells irradiated with accelerated carbon ions. Advances in Space Research 18:1-2, pages 127-136.
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M. Durante, G.F. Grossi & T.C. Yang. (1996) Radiation-induced chromosomal instability in human mammary epithelial cells. Advances in Space Research 18:1-2, pages 99-108.
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Manabu Yamazaki, Michiko Tsuchida, Ken‐yu Kobayashi, Toshiaki Takezawa & Yuichi Mori. (2004) A novel method to prepare multicellular spheroids from varied cell types. Biotechnology and Bioengineering 48:1, pages 17-24.
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