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International Journal of Radiation Biology Volume 64, 1993 - Issue 2
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Original Article

Radioprotective Effects of Cimetidine in Mouse Bone Marrow Cells Exposed to γ-rays as Assayed by the Micronucleus Test

H. Mozdarani School of Medical Sciences, Tarbiat Modarres University, PO Box 14155-4838, Tehran, I.R., Iran
&
A. Gharbali School of Medical Sciences, Tarbiat Modarres University, PO Box 14155-4838, Tehran, I.R., Iran
Pages 189-194 | Received 08 Sep 1992, Accepted 18 Mar 1993, Published online: 03 Jul 2009

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Simin Fazelipour, Seyyed B. Kiaei, Zahra Tootian, Seyyed A. Haeri, Omid Zehtabvar & Javad Sadeghinezhad. (2015) Cimetidine administration decreases radiogenic damage on the thyroid gland in mice. International Journal of Radiation Biology 91:3, pages 218-223.
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Articles from other publishers (22)

Leyla Ansari, Amin Banaei, Leila Dastranj, Mehrsa Majdaeen, Hassan Vafapour, Hamed Zamani, Gholamreza Ataei & Razzagh Abedi-Firouzjah. (2021) Evaluating the radioprotective effect of single dose and daily oral consumption of green tea, grape seed, and coffee bean extracts against gamma irradiation. Applied Radiation and Isotopes 174, pages 109781.
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KarimAfsar dizaj, AliShabestani Monfared, Hossein Mozdarani, Ali Naeiji, Abolfazl Razzaghdoust, Karimollah Hajian-tilaki, Bahareh Aboufazeli, Fatemeh Niksirat & Sajad Borzoueisileh. (2021) Combined effect of oral famotidine and cimetidine on the survival of lethally irradiated mice: An in vivo study. Journal of Cancer Research and Therapeutics 17:4, pages 865.
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Serazhutdin Abdullaev, Gulchachak Minkabirova, Ekaterina Karmanova, Vadim Bruskov & Azhub Gaziev. (2018) Metformin prolongs survival rate in mice and causes increased excretion of cell-free DNA in the urine of X-irradiated rats. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 831, pages 13-18.
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Ding-Wen Jiang, Qing-Rong Wang, Xian-Rong Shen, Ying He, Tian-Tian Qian, Qiong Liu, Deng-Yong Hou, Yu-Ming Liu, Wei Chen, Xin Ren & Ke-Xian Li. (2017) Radioprotective effects of cimetidine on rats irradiated by long-term, low-dose-rate neutrons and 60Co γ-rays. Military Medical Research 4:1.
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Laura Bannister, Rebecca Mantha, Yvonne Devantier, Eugenia Petoukhov, Chantal Brideau, Mandy Serran & Dmitry Klokov. (2016) Dose and Radioadaptive Response Analysis of Micronucleus Induction in Mouse Bone Marrow. International Journal of Molecular Sciences 17:9, pages 1548.
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M. Zangeneh, H. Mozdarani & A. Mahmoudzadeh. (2015) Potent radioprotective effects of combined regimens of famotidine and vitamin C against radiation-induced micronuclei in mouse bone marrow erythrocytes. Radiation and Environmental Biophysics 54:2, pages 175-181.
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A. Razzaghdoust, H. Mozdarani & B. Mofid. (2014) Famotidine as a radioprotector for rectal mucosa in prostate cancer patients treated with radiotherapyFamotidin als Schutz der Enddarmschleimhaut vor Strahlenbelastung während der Strahlentherapie von Prostatakarzinompatienten. Strahlentherapie und Onkologie 190:8, pages 739-744.
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Abolfazl Razzaghdoust, Hossein Mozdarani, Bahram Mofid, S. Mahmoud R. Aghamiri & Amir H. Heidari. (2014) Reduction in radiation-induced lymphocytopenia by famotidine in patients undergoing radiotherapy for prostate cancer. The Prostate 74:1, pages 41-47.
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Neide Galvão Nascimento, Marlos Cortez Sampaio, Renata Amaral Olivo & Catarina Teixeira. (2010) Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators involved. Toxicon 55:2-3, pages 343-352.
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Mahmoud Toulany, Rainer Kehlbach, H. Peter Rodemann & Hossein Mozdarani. (2010) Radiocontrast media affect radiation-induced DNA damage repair in vitro and in vivo by affecting Akt signalling. Radiotherapy and Oncology 94:1, pages 110-116.
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H. Mozdarani & P. Ghoraeian. (2008) Modulation of gamma-ray-induced apoptosis in human peripheral blood leukocytes by famotidine and vitamin C. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 649:1-2, pages 71-78.
Crossref
Seyed Jalal Hosseinimehr, Aziz Mahmoudzadeh & Shahram Akhlagpour. (2006) Captopril protects mice bone marrow cells against genotoxicity induced by gamma irradiation. Cell Biochemistry and Function 25:4, pages 389-394.
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Seyed Jalal HOSSEINIMEHR, Mohammad AZADBAKHT, Seyedeh Maryam MOUSAVI, Aziz MAHMOUDZADEH & Shahram AKHLAGHPOOR. (2007) Radioprotective Effects of Hawthorn Fruit Extract Against Gamma Irradiation in Mouse Bone Marrow Cells. Journal of Radiation Research 48:1, pages 63-68.
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S J Hosseinimehr & A Nemati. (2006) Radioprotective effects of hesperidin against gamma irradiation in mouse bone marrow cells. The British Journal of Radiology 79:941, pages 415-418.
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SEYED JALAL HOSSEINIMEHR, HASSAN TAVAKOLI, GHOLAMREZA POURHEIDARI, ALIGHOLI SOBHANI & ABBAS SHAFIEE. (2003) Radioprotective Effects of Citrus Extract Against γ-Irradiation in Mouse Bone Marrow Cells. Journal of Radiation Research 44:3, pages 237-241.
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HOSSEIN MOZDARANI. (2003) Radioprotective Properties of Histamine H2 Receptor Antagonists: Present and Future Prospects.. Journal of Radiation Research 44:2, pages 145-149.
Crossref
David Murray & William H. McBride. 2001. Kirk-Othmer Encyclopedia of Chemical Technology. Kirk-Othmer Encyclopedia of Chemical Technology.
YURI MIURA, KAZUNORI ANZAI, JUN-ICHI UEDA & TOSHIHIKO OZAWA. (2000) Novel Approach to In Vivo Screening for Radioprotective Activity in Whole Mice: In Vivo Electron Spin Resonance Study Probing the Redox Reaction of Nitroxyl. Journal of Radiation Research 41:2, pages 103-111.
Crossref
Hossein Mozdarani & Shahdokht Kamali. (1998) Antigenotoxic effects of cimetidine against benzene induced micronuclei in mouse bone marrow erythrocytes. Toxicology Letters 99:1, pages 53-61.
Crossref
Hossein Mozdarani & Ali R Khoshbin-Khoshnazar. (1998) In vivo protection by cimetidine against fast neutron-induced micronuclei in mouse bone marrow cells. Cancer Letters 124:1, pages 65-71.
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Hossein Mozdarani & Ali H. Saberi. (1994) Induction of cytogenetic adaptive response of mouse bone marrow cells to radiation by therapeutic doses of bleomycin sulfate and actinomycin D as assayed by the micronucleus test. Cancer Letters 78:1-3, pages 141-150.
Crossref
Michael F. Salamone & Kathleen H. Mavournin. (2006) Bone marrow micronucleus assay: A review of the mouse stocks used and their published mean spontaneous micronucleus frequencies. Environmental and Molecular Mutagenesis 23:4, pages 239-273.
Crossref

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