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Original Article

Radiation-induced DNA Damage and Repair in Radiosensitive and Radioresistant Human Tumour Cells Measured by Field Inversion Gel Electrophoresis

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Pages 703-713 | Received 29 Jun 1992, Accepted 16 Nov 1992, Published online: 03 Jul 2009

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Read on this site (6)

Kurt G. Hofer, Xiao Lin & Shi-Ping Bao. (1996) Dna Damage, Micronucleus Formation, And Cell Death from 125I Decays in Dna. Acta Oncologica 35:7, pages 825-832.
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J. M. COCO-MARTIN. (1996) Lethality of radiation-induced chromosome aberrations in human tumour cell lines with different radiosensitivities. International Journal of Radiation Biology 69:3, pages 337-344.
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J. BUSSINK. (1996) Repair of chromosome and DNA breaks versus cell survival in Chinese hamster cells. International Journal of Radiation Biology 70:1, pages 23-32.
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J.M. Coco-Martin, M.F.M.A. Smeets, M. Poggensee, E. Mooren, I. Hofland, M. van den Brug, C. Ottenheim, H. Bartelink & A.C. Begg. (1994) Use of Fluorescence in Situ Hybridization to Measure Chromosome Aberrations as a Predictor of Radiosensitivity in Human Tumour Cells. International Journal of Radiation Biology 66:3, pages 297-307.
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N. Zaffaroni, L. Orlandi, R. Villa, A. Bearzatto, E.K. Rofstad & R. Silvestrini. (1994) DNA Double-strand Break Repair and Radiation Response in Human Tumour Primary Cultures. International Journal of Radiation Biology 66:3, pages 279-285.
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M. Rosemann, B. Kanon, A.W.T. Konings & H.H. Kampinga. (1993) An Image Analysis Technique for Detection of Radiation-induced DNA Fragmentation after CHEF Electrophoresis. International Journal of Radiation Biology 64:2, pages 245-249.
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Articles from other publishers (20)

Lei Zhao, Di Wu, Dong Mi & Yeqing Sun. (2017) Radiosensitivity and relative biological effectiveness based on a generalized target model. Journal of Radiation Research 58:1, pages 8-16.
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Iwona Grądzka & Teresa Iwaneńko. (2005) A non-radioactive, PFGE-based assay for low levels of DNA double-strand breaks in mammalian cells. DNA Repair 4:10, pages 1129-1139.
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Sheela Prithivirajsingh, Michael D Story, Sherry A Bergh, Fady B Geara, K Kian Ang, Sheikh M Ismail, Craig W Stevens, Thomas A Buchholz & William A Brock. (2004) Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation. FEBS Letters 571:1-3, pages 227-232.
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Jean-François Rosier, Lucienne Michaux, Geneviève Ameye, Björn Cedervall, Jeanne-Marie Libouton, Michèle Octave-Prignot, Christine Verellen-Dumoulin, Pierre Scalliet & Vincent Grégoire. (2003) The radioenhancement of two human head and neck squamous cell carcinomas by 2′-2′ difluorodeoxycytidine (gemcitabine; dFdC) is mediated by an increase in radiation-induced residual chromosome aberrations but not residual DNA DSBs. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 527:1-2, pages 15-26.
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Bilikere S Dwarkanath, Frido Zolzer, Sudhir Chandana, Thomas Bauch, Jawahar S Adhikari, Wolfgang U Muller, Christian Streffer & Viney Jain. (2001) Heterogeneity in 2-deoxy-D-glucose–induced modifications in energetics and radiation responses of human tumor cell lines. International Journal of Radiation Oncology*Biology*Physics 50:4, pages 1051-1061.
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Masao Suzuki, Yoko Kase, Hiroshi Yamaguchi, Tatsuaki Kanai & Koichi Ando. (2000) Relative biological effectiveness for cell-killing effect on various human cell lines irradiated with heavy-ion medical accelerator in Chiba (HIMAC) carbon-ion beams. International Journal of Radiation Oncology*Biology*Physics 48:1, pages 241-250.
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M. E. Price, V. J. McKelvey-Martin, T. Robson, D. G. Hirst & S. R. McKeown. (2000) Induction and Rejoining of DNA Double-Strand Breaks in Bladder Tumor Cells. Radiation Research 153:6, pages 788-794.
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R A Britten, S Kuny & S Perdue. (1999) Modification of non-conservative double-strand break (DSB) rejoining activity after the induction of cisplatin resistance in human tumour cells. British Journal of Cancer 79:5-6, pages 843-849.
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Anya G Polischouk, Björn Cedervall, Siv Ljungquist, Jenny Flygare, Dennis Hellgren, Reidar Grénman & Rolf Lewensohn. (1999) DNA double-strand break repair, DNA-PK, and DNA ligases in two human squamous carcinoma cell lines with different radiosensitivity. International Journal of Radiation Oncology*Biology*Physics 43:1, pages 191-198.
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M.J. Flores, T. Ortiz, J. Piñero & F. Cortés. (1998) Protection provided by exogenous DNA ligase in G0 human lymphocytes treated with restriction enzyme MspI or bleomycin as shown by the comet assay. Environmental and Molecular Mutagenesis 32:4, pages 336-343.
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N. Foray, C.F. Arlett & E.P. Malaise. (1997) Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: A closer look. Biochimie 79:9-10, pages 567-575.
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A.T. Gordon & T.J. McMillan. (1997) A role for molecular radiobiology in radiotherapy?. Clinical Oncology 9:2, pages 70-78.
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Maria A.W.H. van Waarde, Annette J. van Assen, Antonius W.T. Konings & Harm H. Kampinga. (1996) Feasibility of measuring radiation-induced DNA double strand breaks and their repair by pulsed field gel electrophoresis in freshly isolated cells from the mouse RIF-1 tumor. International Journal of Radiation Oncology*Biology*Physics 36:1, pages 125-134.
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P. Virsik-Peuckert, M. Rave-Fränk & H. Schmidberger. (1996) Further studies on the possible relationship between radiation-induced reciprocal translocations and intrinsic radiosensitivity of human tumor cells. Radiotherapy and Oncology 40:2, pages 111-119.
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Peter G. Sacks. (1996) Cell, tissue and organ culture as in vitro models to study the biology of squamous cell carcinomas of the head and neck. Cancer and Metastasis Review 15:1, pages 27-51.
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Elies C. Woudstra, Jeanette F. Brunsting, Judith M. Roesink, Antonius W.T. Konings & Harm H. Kampinga. (1996) Radiation induced DNA damage and damage repair in three human tumour cell lines. Mutation Research/DNA Repair 362:1, pages 51-59.
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Ludwika Kreja, Christoph Selig, Ulla Plappert & Wilhelm Nothdurft. (1996) Radiation-induced DNA damage in canine hemopoietic cells and stromal cells as measured by the comet assay. Environmental and Molecular Mutagenesis 27:1, pages 39-45.
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Jean Francisco, Olivier Pauwels, Stéphane Simon, Plinio Gasperin, Paul Van Houtte, Jean-Lambert Pasteels & Robert Kiss. (1995) Computer-assisted morphonuclear characterization of radiotherapy-induced effects in MXT mouse mammary adenocarcinomas surviving earlier radiotherapy. International Journal of Radiation Oncology*Biology*Physics 32:2, pages 409-419.
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M.F.M.A. Smeets, E.H.M. Mooren & A.C. Begg. (1994) The effect of radiation on G2 blocks, cyclin B expression and cdc2 expression in human squamous carcinoma cell lines with different radiosensitivities. Radiotherapy and Oncology 33:3, pages 217-227.
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Reinhard Wurm, Neil G. Burnet, Nisha Duggal, John R. Yarnold & John H. Peacock. (1994) Cellular radiosensitivity and dna damage in primary human fibroblasts. International Journal of Radiation Oncology*Biology*Physics 30:3, pages 625-633.
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