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Original Article

Use of Radiation Quality as a Probe for DNA Lesion Complexity

Pages 43-48 | Received 10 Aug 1993, Accepted 03 Sep 1993, Published online: 03 Jul 2009

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Read on this site (11)

Tomoko Abe, Yusuke Kazama & Tomonari Hirano. (2015) Ion Beam Breeding and Gene Discovery for Function Analyses Using Mutants. Nuclear Physics News 25:4, pages 30-34.
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P-W Chang, Q-M Zhang, K Takatori, A Tachibana & S Yonei. (2005) Increased sensitivity to sparsely ionizing radiation due to excessive base excision in clustered DNA damage sites in . International Journal of Radiation Biology 81:2, pages 115-123.
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T. Ohnishi, A. Takahashi, T. Yano, H. Matsumoto, X. Wang, K. Ohnishi, T. Tamamoto, K. Tsuji, Y. Furusawa & O. Yukawa. (1998) Hyperthermic enhancement of tumour growth inhibition by accelerated carbon-ions in transplantable human esophageal cancer. International Journal of Hyperthermia 14:2, pages 195-202.
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W. SONTAG. (1997) A discrete cell survival model including repair after high dose-rate of ionizing radiation. International Journal of Radiation Biology 71:2, pages 129-144.
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H. C. NEWMAN, K. M. PRISE, M. FOLKARD and B. D. MICHAEL. (1997) DNA double-strand break distributions in X-ray and alpha-particle irradiated V79 cells: evidence for non-random breakage. International Journal of Radiation Biology 71:4, pages 347-363.
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A. OTTOLENGHI, F. MONFORTI and M. MERZAGORA. (1997) A Monte Carlo calculation of cell inactivation by light ions. International Journal of Radiation Biology 72:5, pages 505-513.
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S. RITTER. (1996) Comparison of chromosomal damage induced by X-rays and Ar ions with an LET of 1840 keV/ mum in G1 V79 cells. International Journal of Radiation Biology 69:2, pages 155-166.
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B. D. MICHAEL. (1996) A multiple-radical model for radiation action on DNA and the dependence of OER on LET. International Journal of Radiation Biology 69:3, pages 351-358.
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J. Heilmann, G. Taucher-Scholz & G. Kraft. (1995) Induction of DNA Double-strand Breaks in CHO-K1 Cells by Carbon Ions. International Journal of Radiation Biology 68:2, pages 153-162.
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K.M. Prise, M. Folkard, H.C. Newman & B.D. Michael. (1994) Effect of Radiation Quality on Lesion Complexity in Cellular DNA. International Journal of Radiation Biology 66:5, pages 537-542.
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V. Michalik & D. Frankenberg. (1994) Simple and Complex Double-strand Breaks Induced by Electrons. International Journal of Radiation Biology 66:5, pages 467-470.
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Articles from other publishers (36)

Igor Shuryak. (2019) Enhancing low-dose risk assessment using mechanistic mathematical models of radiation effects. Journal of Radiological Protection 39:4, pages S1-S13.
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Michael N. Cornforth & Bradford D. Loucas. (2018) A Cytogenetic Profile of Radiation Damage. Radiation Research 191:1, pages 1.
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Susanne Burdak-Rothkamm & Kai Rothkamm. (2018) Radiation-induced bystander and systemic effects serve as a unifying model system for genotoxic stress responses. Mutation Research/Reviews in Mutation Research 778, pages 13-22.
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Robert D. Stewart. (2018) Induction of DNA Damage by Light Ions Relative to 60 Co γ-rays . International Journal of Particle Therapy 5:1, pages 25-39.
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Christian P Karger & Peter Peschke. (2017) RBE and related modeling in carbon-ion therapy. Physics in Medicine & Biology 63:1, pages 01TR02.
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Bradford D. Loucas & Michael N. Cornforth. (2013) The LET Dependence of Unrepaired Chromosome Damage in Human Cells: A Break Too Far?. Radiation Research 179:4, pages 393-405.
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Ryuichi Okayasu. (2011) Repair of DNA damage induced by accelerated heavy ions—A mini review. International Journal of Cancer 130:5, pages 991-1000.
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Glen A. Bird. 2012. Encyclopedia of Sustainability Science and Technology. Encyclopedia of Sustainability Science and Technology 5572 5619 .
A Carabe-Fernandez, R G Dale & H Paganetti. (2011) Repair kinetic considerations in particle beam radiotherapy. The British Journal of Radiology 84:1002, pages 546-555.
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Lori J. Chappell, Mary K. Whalen, Sheena Gurai, Artem Ponomarev, Francis A. Cucinotta & Janice M. Pluth. (2010) Analysis of Flow Cytometry DNA Damage Response Protein Activation Kinetics after Exposure to X Rays and High-Energy Iron Nuclei. Radiation Research 174:6a, pages 691-702.
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Uli Weber & Gerhard Kraft. (2009) Comparison of Carbon Ions Versus Protons. The Cancer Journal 15:4, pages 325-332.
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Mary K. Whalen, Sukhleen K. Gurai, Hengameh Zahed-Kargaran & Janice M. Pluth. (2008) Specific ATM-Mediated Phosphorylation Dependent on Radiation Quality. Radiation Research 170:3, pages 353-364.
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Nathalie Gault, Odile Rigaud, Jean-Luc Poncy & Jean-Louis Lefaix. (2007) Biochemical Alterations in Human Cells Irradiated with α Particles Delivered by Macro- or Microbeams. Radiation Research 167:5, pages 551-562.
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Hatim Fakir, Rainer K. Sachs, Bo Stenerlöw & Werner Hofmann. (2006) Clusters of DNA Double-Strand Breaks Induced by Different Doses of Nitrogen Ions for Various LETs: Experimental Measurements and Theoretical Analyses. Radiation Research 166:6, pages 917-927.
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M. Scholz. 2006. Microdosimetric Response of Physical and Biological Systems to Low- and High-LET Radiations. Microdosimetric Response of Physical and Biological Systems to Low- and High-LET Radiations 1 73 .
Dalong Pang, James E. Rodgers, Barry L. Berman, Sergey Chasovskikh & Anatoly Dritschilo. (2005) Spatial Distribution of Radiation-Induced Double-Strand Breaks in Plasmid DNA as Resolved by Atomic Force Microscopy. Radiation Research 164:6, pages 755-765.
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M. Pinto, K. M. Prise & B. D. Michael. (2005) Evidence for Complexity at the Nanometer Scale of Radiation-Induced DNA DSBs as a Determinant of Rejoining Kinetics. Radiation Research 164:1, pages 73-85.
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E. Tsoulou, C. A. Kalfas & E. G. Sideris. (2005) Conformational Properties of DNA after Exposure to Gamma Rays and Neutrons. Radiation Research 163:1, pages 90-97.
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M. Pinto, K. M. Prise & B. D. Michael. (2004) A Monte Carlo Model of DNA Double-Strand Break Clustering and Rejoining Kinetics for the Analysis of Pulsed-Field Gel Electrophoresis Data. Radiation Research 162:4, pages 453-463.
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Hooshang Nikjoo & Shuzo Uehara. 2003. Charged Particle and Photon Interactions with Matter. Charged Particle and Photon Interactions with Matter.
Yong Zhao, Zheng Tan, Yan-hua Du & Guan-ying Qiu. (2003) Electrophoresis examination of strand breaks in plasmid DNA induced by low-energy nitrogen ion irradiation. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 211:2, pages 211-218.
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M. Scholz. 2003. Radiation Effects on Polymers for Biological Use. Radiation Effects on Polymers for Biological Use 95 155 .
Björn Rydberg, Lawrence Heilbronn, William R. Holley, Markus Löbrich, Cary Zeitlin, Aloke Chatterjee & Priscilla K. Cooper. (2002) Spatial Distribution and Yield of DNA Double-Strand Breaks Induced by 3–7 MeV Helium Ions in Human Fibroblasts. Radiation Research 158:1, pages 32-42.
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J-P. Pouget, S. Frelon, J-L. Ravanat, I. Testard, F. Odin & J. Cadet. (2002) Formation of Modified DNA Bases in Cells Exposed either to Gamma Radiation or to High-LET Particles 1 . Radiation Research 157:5, pages 589-595.
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B. Fayard, A. Touati, F. Abel, M. A. Herve du Penhoat, I. Despiney-Bailly, F. Gobert, M. Ricoul, A. L'Hoir, M. F. Politis, M. A. Hill, D. L. Stevens, L. Sabatier, E. Sage, D. T. Goodhead & A. Chetioui. (2002) Cell Inactivation and Double-Strand Breaks: The Role of Core Ionizations, as Probed by Ultrasoft X Rays. Radiation Research 157:2, pages 128-140.
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Akihisa Takahashi, Ken Ohnishi, Xinjiang Wang, Misaki Kobayashi, Hideki Matsumoto, Tetsuro Tamamoto, Hideo Aoki, Yoshiya Furusawa, Osami Yukawa & Takeo Ohnishi. (2000) The dependence of p53 on the radiation enhancement of thermosensitivity at different let. International Journal of Radiation Oncology*Biology*Physics 47:2, pages 489-494.
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E. Lukášová, S. Kozubek, R. Govorun, M. Repin, L. Rýznar, E. Krasavin, M. Kozubek & V. Kroha. 1999. Fundamentals for the Assessment of Risks from Environmental Radiation. Fundamentals for the Assessment of Risks from Environmental Radiation 195 202 .
. (2016) Genetic susceptibility to cancer: ICRP Publication 79. Annals of the ICRP 28:1-2, pages 1-157.
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Akihisa Takahashi, Tomoaki Yano, Hideki Matsumoto, Xinjiang Wang, Ken Ohnishi, Tetsurou Tamamoto, Kou Tsuji, Osami Yukawa & Takeo Ohnishi. (1998) Effects of accelerated carbon-ions on growth inhibition of transplantable human esophageal cancer in nude mice. Cancer Letters 122:1-2, pages 181-186.
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E Nasonova, S Ritter, T Fomenkova & G Kraft. (1998) Induction of chromosomal damage in CHO-K1 cells and their repair-deficient mutant xrs5 by X-ray and particle irradiation. Advances in Space Research 22:4, pages 569-578.
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B E Lehnert & E H Goodwin. (1997) A new mechanism for DNA alterations induced by alpha particles such as those emitted by radon and radon progeny.. Environmental Health Perspectives 105:suppl 5, pages 1095-1101.
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M. Ahmad Chaudhry & Michael Weinfeld. (1997) Reactivity of Human Apurinic/Apyrimidinic Endonuclease andEscherichia coli Exonuclease III with Bistranded Abasic Sites in DNA. Journal of Biological Chemistry 272:25, pages 15650-15655.
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G. Taucher-Scholz, J. Heilmann & G. Kraft. (1996) Induction of DNA strand breaks by heavy ions. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 107:1-4, pages 318-322.
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D. T. Goodhead. (1995) Molecular and cell models of biological effects of heavy ion radiation. Radiation and Environmental Biophysics 34:2, pages 67-72.
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J. Cadet, I. Girault, M. Gromova, D. Molko, F. Odin & M. Polverelli. (1995) Effects of heavy ions on nucleic acids: Measurement of the damage. Radiation and Environmental Biophysics 34:1, pages 55-57.
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N. Foray, C.F. Arlett & E.P. Malaise. (1995) Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia telangiectasia human fibroblast cell line. Biochimie 77:11, pages 900-905.
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