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Original Article

An Ionizing Radiation-sensitive Mutant of CHO Cells: Irs-20. III. Chromosome Aberrations, DNA Breaks and Mitotic Delay

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Pages 571-582 | Received 21 Jul 1993, Accepted 10 Jan 1994, Published online: 03 Jul 2009

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R. K. Ratnayake, V. A. Semenenko & R. D. Stewart. (2006) Retrospective analysis of double-strand break rejoining data collected using warm-lysis PFGE protocols. International Journal of Radiation Biology 82:2, pages 139-139.
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R. K. Ratnayake, V. A. Semenenko & R. D. Stewart. (2005) Retrospective analysis of double-strand break rejoining data collected using warm-lysis PFGE protocols. International Journal of Radiation Biology 81:6, pages 421-428.
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Articles from other publishers (16)

Yu-Fen Lin, Hatsumi Nagasawa, John B. Little, Takamitsu A. Kato, Hung-Ying Shih, Xian-Jin Xie, Paul F. Wilson Jr.John R. Brogan, Akihiro Kurimasa, David J. Chen, Joel S. Bedford & Benjamin P. C. Chen. (2014) Differential Radiosensitivity Phenotypes of DNA-PKcs Mutations Affecting NHEJ and HRR Systems following Irradiation with Gamma-Rays or Very Low Fluences of Alpha Particles. PLoS ONE 9:4, pages e93579.
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Xiaoyan Yu, Hongyan Wang, Ping Wang, Benjamin P.C. Chen & Ya Wang. (2011) The Ku-dependent non-homologous end-joining pathway contributes to low-dose radiation-stimulated cell survival. Journal of Cellular Physiology 226:2, pages 369-374.
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Hatsumi Nagasawa, John B. Little, Yu-Fen Lin, Sairei So, Akihiro Kurimasa, Yuanlin Peng, John R. Brogan, David J. Chen, Joel S. Bedford & Benjamin P. C. Chen. (2011) Differential Role of DNA-PKcs Phosphorylations and Kinase Activity in Radiosensitivity and Chromosomal Instability. Radiation Research 175:1, pages 83-89.
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Hatsumi Nagasawa, John R. Brogan, Yuanlin Peng, John B. Little & Joel S. Bedford. (2010) Some unsolved problems and unresolved issues in radiation cytogenetics: A review and new data on roles of homologous recombination and non-homologous end joining. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 701:1, pages 12-22.
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Satyendra K. Singh, Weizhong Wu, Wenqi Wu, Minli Wang & George Iliakis. (2009) Extensive Repair of DNA Double-Strand Breaks in Cells Deficient in the DNA-PK-Dependent Pathway of NHEJ after Exclusion of Heat-Labile Sites. Radiation Research 172:2, pages 152.
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. 2008. Beyond Apoptosis. Beyond Apoptosis 41 53 .
Takamitsu A. Kato, Paul F. Wilson, Hatsumi Nagasawa, Markus M. Fitzek, Michael M. Weil, John B. Little & Joel S. Bedford. (2007) A defect in DNA double strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans. DNA Repair 6:6, pages 818-829.
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Takamitsu A. Kato, Hatsumi Nagasawa, Michael M. Weil, J. B. Little & J. S. Bedford. (2006) Levels of γ-H2AX Foci after Low-Dose-Rate Irradiation Reveal a DNA DSB Rejoining Defect in Cells from Human ATM Heterozygotes in Two AT Families and in Another Apparently Normal Individual . Radiation Research 166:3, pages 443-453.
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Susan M. Bailey & Joel S. Bedford. (2006) Studies on chromosome aberration induction: What can they tell us about DNA repair?. DNA Repair 5:9-10, pages 1171-1181.
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Yuanlin Peng, Rick G. Woods, Heather Beamish, Ruiqiong Ye, Susan P. Lees-Miller, Martin F. Lavin & Joel S. Bedford. (2005) Deficiency in the Catalytic Subunit of DNA-Dependent Protein Kinase Causes Down-Regulation of ATM. Cancer Research 65:5, pages 1670-1677.
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Kerstin Borgmann, Mirco Dede, Agnieszka Wrona, Ingo Brammer, Jens Overgaard & Ekkehard Dikomey. (2004) For X-irradiated normal human fibroblasts, only half of cell inactivation results from chromosomal damage. International Journal of Radiation Oncology*Biology*Physics 58:2, pages 445-452.
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Joel S. Bedford & William C. Dewey. (2002) Historical and Current Highlights in Radiation Biology: Has Anything Important Been Learned by Irradiating Cells?. Radiation Research 158:3, pages 251-291.
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R. D. Stewart. (2001) Two-Lesion Kinetic Model of Double-Strand Break Rejoining and Cell Killing. Radiation Research 156:4, pages 365-378.
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Nesrin A Asaad, Zhao-Chong Zeng, Jun Guan, John Thacker & George Iliakis. (2000) Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants. Oncogene 19:50, pages 5788-5800.
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A van Duijn-Goedhart, M.Z Zdzienicka, K Sankaranarayanan & P.P.W van Buul. (2000) Differential responses of Chinese hamster mutagen sensitive cell lines to low and high concentrations of calicheamicin and neocarzinostatin. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 471:1-2, pages 95-105.
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Fanqing Chen, Scott R Peterson, Michael D Story & David J Chen. (1996) Disruption of DNA-PK in Ku80 mutant xrs-6 and the implications in DNA double-strand break repair. Mutation Research/DNA Repair 362:1, pages 9-19.
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