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Original Article

Cellular Radiosensitivity in Ataxia-telangiectasia

Pages S87-S96 | Received 23 May 1994, Accepted 16 Jul 1994, Published online: 03 Jul 2009

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Read on this site (5)

Parisa Amirifar, Mohammad Reza Ranjouri, Martin Lavin, Hassan Abolhassani, Reza Yazdani & Asghar Aghamohammadi. (2020) Ataxia-telangiectasia: epidemiology, pathogenesis, clinical phenotype, diagnosis, prognosis and management. Expert Review of Clinical Immunology 16:9, pages 859-871.
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Penny Jeggo & Martin F. Lavin. (2009) Cellular radiosensitivity: How much better do we understand it?. International Journal of Radiation Biology 85:12, pages 1061-1081.
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Wim Jongmans, Michèle Vuillaume, Krystyna Chrzanowska, Dominique Smeets, Karl Sperling & Janet Hall. (1997) Nijmegen Breakage Syndrome Cells Fail To Induce the p53-Mediated DNA Damage Response following Exposure to Ionizing Radiation. Molecular and Cellular Biology 17:9, pages 5016-5022.
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A. ANTOCCIA, R. RICORDY, P. MARASCHIO, S. PRUDENTE and C. TANZARELLA. (1997) Chromosomal sensitivity to clastogenic agents and cell cycle perturbations in Nijmegen Breakage Syndrome lymphoblastoid cell lines. International Journal of Radiation Biology 71:1, pages 41-49.
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E. C. WOUDSTRA. (1996) Chromatin structure and cellular radiosensitivity: a comparison of two human tumour cell lines. International Journal of Radiation Biology 70:6, pages 693-703.
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Shinji Yasuhira, Takeshi Saito, Chihaya Maesawa & Tomoyuki Masuda. (2012) Sensor and effector kinases in DNA damage checkpoint regulate capacity for homologous recombination repair of fission yeast in G2 phase. DNA Repair 11:8, pages 666-675.
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Pankaj Kumar Singh, Raj Kumar, Ashok Sharma, Rajesh Arora, Raman Chawla, Swatantra Kumar Jain, Rajendra Prasad Tripathi & Rakesh Kumar Sharma. (2011) Role of Apoptotic Proteins in REC-2006 Mediated Radiation Protection in Hepatoma Cell Lines. Evidence-Based Complementary and Alternative Medicine 2011, pages 1-11.
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Yuko Fukuda, Reiko Ishida, Katsunori Aoki, Kazuhiko Nakahara, Tohru TakashiKeiji Mochida, Osamu Suzuki, Junichiro Matsuda & Masataka Kasai. (2008) Contribution of Translin to Hematopoietic Regeneration after Sublethal Ionizing Irradiation. Biological and Pharmaceutical Bulletin 31:2, pages 207-211.
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Momoe KAN'O, Tetsuya KAWATA, Hisao ITO, Naoyuki SHIGEMATSU, Cuihua LIU, Takashi UNO, Kouich ISOBE, Hiroyuki KAWAKAMI, Francis CUCINOTTA, Kerry GEORGE & Atsushi KUBO. (2007) Repair of Potentially Lethal Damage in Normal Cells and Ataxia Telangiectasia Cells; Consideration of Non-Homologous End-Joining. Journal of Radiation Research 48:1, pages 31-38.
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Yadvinder Bhuller & Peter G. Wells. (2006) A Developmental Role for Ataxia-Telangiectasia Mutated in Protecting the Embryo from Spontaneous and Phenytoin-Enhanced Embryopathies in Culture. Toxicological Sciences 93:1, pages 156-163.
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Shuji Kishi. 2006. Handbook of Models for Human Aging. Handbook of Models for Human Aging 317 338 .
Markus Löbrich & Penny A. Jeggo. (2005) The two edges of the ATM sword: Co-operation between repair and checkpoint functions. Radiotherapy and Oncology 76:2, pages 112-118.
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Tetsuya Kawata, Hisao Ito, Kerry George, Honglu Wu, Takashi Uno, Kouichi Isobe & Francis A. Cucinotta. (2003) Radiation-Induced Chromosome Aberrations in Ataxia Telangiectasia Cells: High Frequency of Deletions and Misrejoining Detected by Fluorescence In Situ Hybridization . Radiation Research 159:5, pages 597-603.
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Mark O’Driscoll & Penny Jeggo. (2002) Immunological disorders and DNA repair. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 509:1-2, pages 109-126.
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Reiko Ishida, Haruo Okado, Hiroko Sato, Chieko Shionoiri, Katsunori Aoki & Masataka Kasai. (2002) A role for the octameric ring protein, Translin, in mitotic cell division. FEBS Letters 525:1-3, pages 105-110.
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M. E. Karabinis, D. Larson, C. Barlow, A. Wynshaw-Boris & A. R. Moser. (2001) Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in ApcMin/+ mice. Carcinogenesis 22:2, pages 343-346.
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Patrick Sung, Kelly Miguel Trujillo & Stephen Van Komen. (2000) Recombination factors of Saccharomyces cerevisiae. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 451:1-2, pages 257-275.
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P. Formichi, C. Battisti, S.A. Tripodi, P. Tosi & A. Federico. (2000) Apoptotic response and cell cycle transition in ataxia telangiectasia cells exposed to oxidative stress. Life Sciences 66:20, pages 1893-1903.
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Deniz Meydan, Tohr Nilsson, Magnus Törnblom, Lars Hagmar, Dennis Hellgren, James C Fuscoe & Bo Lambert. (1999) The frequency of illegitimate TCRβ/γ gene recombination in human lymphocytes: influence of age, environmental exposure and cytostatic treatment, and correlation with frequencies of t(14;18) and hprt mutation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 444:2, pages 393-403.
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Robert T. Johnson, Eisuke Gotoh, Ann M. Mullinger, Anderson J. Ryan, Yosef Shiloh, Yael Ziv & Shoshana Squires. (1999) Targeting Double-Strand Breaks to Replicating DNA Identifies a Subpathway of DSB Repair That Is Defective in Ataxia-Telangiectasia Cells. Biochemical and Biophysical Research Communications 261:2, pages 317-325.
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Gang Chen, Shyng-Shiou F. Yuan, Wei Liu, Yang Xu, Kelly Trujillo, Binwei Song, Feng Cong, Stephen P. Goff, Yun Wu, Ralph Arlinghaus, David Baltimore, Paul J. Gasser, Min S. Park, Patrick Sung & Eva Y.-H.P. Lee. (1999) Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl. Journal of Biological Chemistry 274:18, pages 12748-12752.
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John Thacker. (1999) Repair of ionizing radiation damage in mammalian cells. Alternative pathways and their fidelity. Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie 322:2-3, pages 103-108.
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Carina J. Vessey, Christopher J. Norbury & Ian D. Hickson. 1999. 189 221 .
Eric G. Wright. (1999) Inherited and inducible chromosomal instability: a fragile bridge between genome integrity mechanisms and tumourigenesis. The Journal of Pathology 187:1, pages 19-27.
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Penny A Jeggo, Antony M Carr & Alan R Lehmann. (1998) Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia. Trends in Genetics 14:8, pages 312-316.
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Anna H Nowak-Wegrzyn & Howard M Lederman. (1998) A 7-Year-Old Girl with Cerebral Palsy and Multiple Warts. Annals of Allergy, Asthma & Immunology 81:3, pages 195-201.
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Shlomit Gilad, Luciana Chessa, Rami Khosravi, Pamela Russell, Yaron Galanty, Maria Piane, Richard A. Gatti, Timothy J. Jorgensen, Yosef Shiloh & Anat Bar-Shira. (1998) Genotype-Phenotype Relationships in Ataxia-Telangiectasia and Variants. The American Journal of Human Genetics 62:3, pages 551-561.
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A.R. Lehmann. (1998) Dual functions of DNA repair genes: molecular, cellular, and clinical implications. BioEssays 20:2, pages 146-155.
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Cristina Fantini, Patrizia Vernole, Bruna Tedeschi & Daniela Caporossi. (1998) Sister chromatid exchanges and DNA topoisomerase II inhibitors: effect of low concentrations of etoposide (VP-16) in ataxia telangiectasia lymphoblastoid cell lines. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 412:1, pages 1-7.
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Toshihiko Ozawa, Kouichi Tatsumi & Tada-aki HoriTakashi Imai, Masatake Yamauchi, Naohiko Seki, Takehiko Sugawara, Masashi Sagara, Toshiyuki Saito, Yoichi Matsuda, Hiroko Ito, Takahiro Nagase, Nobuo Nomura & Tada-aki Hori. 1998. Biodefence Mechanisms Against Environmental Stress. Biodefence Mechanisms Against Environmental Stress 135 144 .
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Gang Chen & Eva Y.-H. P. Lee. (1996) The Product of the ATM Gene Is a 370-kDa Nuclear Phosphoprotein. Journal of Biological Chemistry 271:52, pages 33693-33697.
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Y Xu & D Baltimore. (1996) Dual roles of ATM in the cellular response to radiation and in cell growth control.. Genes & Development 10:19, pages 2401-2410.
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Robert G. Bristow, Samuel Benchimol & Richard P. Hill. (1996) The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiotherapy and Oncology 40:3, pages 197-223.
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T Imai, M Yamauchi, N Seki, T Sugawara, T Saito, Y Matsuda, H Ito, T Nagase, N Nomura & T Hori. (1996) Identification and characterization of a new gene physically linked to the ATM gene.. Genome Research 6:5, pages 439-447.
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Chen-Mei Luo, Wei Tang, Kristin L. Mekeel, Jeffrey S. DeFrank, P. Rani Anné & Simon N. Powell. (1996) High Frequency and Error-prone DNA Recombination in Ataxia Telangiectasia Cell Lines. Journal of Biological Chemistry 271:8, pages 4497-4503.
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Stephen P. Jackson. (1996) The recognition of DNA damage. Current Opinion in Genetics & Development 6:1, pages 19-25.
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P. J. Byrd, C. M. McConville, P. Cooper, J. Parkhill, T. Stankovic, G. M. McGuire, J. A. Thick & A. M. R. Taylor. (1996) Mutations Revealed by Sequencing the 5' Half of the Gene for Ataxia Telangiectasia. Human Molecular Genetics 5:1, pages 145-149.
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Marc S. Rudoltz, Kenneth R. Blank, Gary Kao, Ruth J. Muschel & W. Gillies McKenna. (1996) Ionizing radiation and the cell cycle:A review. Radiation Oncology Investigations 4:4, pages 147-158.
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Stephen P. Jackson. (1995) Cancer Predisposition: Ataxia?telangiectasia at the crossroads. Current Biology 5:11, pages 1210-1212.
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Tamar Enoch & Chris Norbury. (1995) Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM. Trends in Biochemical Sciences 20:10, pages 426-430.
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Alan R. Lehmann & Antony M. Carr. (1995) The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer. Trends in Genetics 11:10, pages 375-377.
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N. Foray, C.F. Arlett & E.P. Malaise. (1995) Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia telangiectasia human fibroblast cell line. Biochimie 77:11, pages 900-905.
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