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International Journal of Radiation Biology Volume 67, 1995 - Issue 1
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Original Article

Flow Cytometric Analysis of Micronucleus Induction in Mice by Internal Exposure to 137Cs at Very Low Dose Rates

L. Abramsson-Zetterberg Department of Genetics, Uppsala University, Box 7003, S-75007, Uppsala, Sweden, +46-18671000, +46-18672705
,
J. Grawé Department of Genetics, Uppsala University, Box 7003, S-75007, Uppsala, Sweden, +46-18671000, +46-18672705
&
G. Zetterberg Department of Genetics, Uppsala University, Box 7003, S-75007, Uppsala, Sweden, +46-18671000, +46-18672705
Pages 29-36 | Received 15 Jul 1994, Accepted 23 Sep 1994, Published online: 03 Jul 2009

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Janneke G. F. Hogervorst, Bert-Jan Baars, Leo J. Schouten, Erik J. M. Konings, R. Alexandra Goldbohm & Piet A. van den Brandt. (2010) The carcinogenicity of dietary acrylamide intake: A comparative discussion of epidemiological and experimental animal research. Critical Reviews in Toxicology 40:6, pages 485-512.
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Britt-Marie Svedenst˚l & Karl-Johan Johanson. (1998) Leukocytes and Micronucleated Erythrocytes in Peripheral Blood from Mice Exposed to 50-Hz or 20-kHz Magnetic Fields. Electro- and Magnetobiology 17:2, pages 127-143.
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L. ABRAMSSON-ZETTERBERG. (1996) Ascorbic acid is not clastogenic and does not modify the effect of extended low-dose-rate gamma-irradiation in mouse bone marrow. International Journal of Radiation Biology 70:1, pages 77-81.
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Articles from other publishers (37)

Hitesh V. Motwani, Emelie Westberg, Christian Lindh, Lilianne Abramsson-Zetterberg & Margareta Törnqvist. (2020) Serum albumin adducts, DNA adducts and micronuclei frequency measured in benzo[a]pyrene-exposed mice for estimation of genotoxic potency. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 849, pages 503127.
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Jenny Aasa, Margareta Törnqvist & Lilianne Abramsson-Zetterberg. (2017) Measurement of micronuclei and internal dose in mice demonstrates that 3-monochloropropane-1,2-diol (3-MCPD) has no genotoxic potency in vivo. Food and Chemical Toxicology 109, pages 414-420.
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Pedro Morales-Ramírez, Teresita Vallarino-Kelly & Virginia Cruz-Vallejo. (2017) Genotoxicity kinetics in murine normoblasts as an approach for the in vivo action of difluorodeoxycytidine. Cancer Chemotherapy and Pharmacology 79:5, pages 843-853.
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Jenny Aasa, Lilianne Abramsson-Zetterberg, Henrik Carlsson & Margareta Törnqvist. (2017) The genotoxic potency of glycidol established from micronucleus frequency and hemoglobin adduct levels in mice. Food and Chemical Toxicology 100, pages 168-174.
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N. Kotova, N. Hebert, E.-L. Härnwall, D. Vare, C. Mazurier, L. Douay, D. Jenssen & J. Grawé. (2015) A novel micronucleus in vitro assay utilizing human hematopoietic stem cells. Toxicology in Vitro 29:7, pages 1897-1905.
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Lilianne Abramsson-Zetterberg & Bianca-Maria Maurer. (2015) Fluoranthene and phenantrene, two predominant PAHs in heat-prepared food, do not influence the frequency of micronucleated mouse erythrocytes induced by other PAHs. Toxicology Reports 2, pages 1057-1063.
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Lilianne Abramsson-Zetterberg & Nils-Gunnar Ilbäck. (2013) The synthetic food colouring agent Allura Red AC (E129) is not genotoxic in a flow cytometry-based micronucleus assay in vivo. Food and Chemical Toxicology 59, pages 86-89.
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Lilianne Abramsson-Zetterberg, Rickard Carlsson & Salomon Sand. (2013) The use of immunomagnetic separation of erythrocytes in the in vivo flow cytometer-based micronucleus assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 752:1-2, pages 8-13.
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Hiroshi Moriwaki, Takahiro Nakagawa & Hiromitsu Nakanishi. (2012) Electrospray ionization mass spectrometric observation of the interaction between cesium ions and amino acids. Rapid Communications in Mass Spectrometry 26:23, pages 2822-2826.
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Scott A. Peslak, Jesse Wenger, Jeffrey C. Bemis, Paul D. Kingsley, Jenna M. Frame, Anne D. Koniski, Yuhchyau Chen, Jacqueline P. Williams, Kathleen E. McGrath, Stephen D. Dertinger & James Palis. (2011) Sublethal radiation injury uncovers a functional transition during erythroid maturation. Experimental Hematology 39:4, pages 434-445.
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Lilianne Abramsson-Zetterberg & Kettil Svensson. (2011) 4-Methylbenzophenone and benzophenone are inactive in the micronucleus assay. Toxicology Letters 201:3, pages 235-239.
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Lilianne Abramsson-Zetterberg, Ulla Beckman Sundh & Roland Mattsson. (2010) Cyanobacterial extracts and microcystin-LR are inactive in the micronucleus assay in vivo and in vitro. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 699:1-2, pages 5-10.
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Margareta Törnqvist, Birgit Paulsson, Anna C. Vikström & Fredrik Granath. (2008) Approach for Cancer Risk Estimation of Acrylamide in Food on the Basis of Animal Cancer Tests and in Vivo Dosimetry. Journal of Agricultural and Food Chemistry 56:15, pages 6004-6012.
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Stephen D. Dertinger, Ying Tsai, Irena Nowak, Ollivier Hyrien, Hongliang Sun, Jeffrey C. Bemis, Dorothea K. Torous, Peter Keng, James Palis & Yuhchyau Chen. (2007) Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose–response and time-course profiles measured by flow cytometry. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 634:1-2, pages 119-125.
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Lilianne Abramsson-Zetterberg, Madelene Svensson & Lars Johnsson. (2007) No evidence of genotoxic effect in vivo of the phytosterol oxidation products triols and epoxides. Toxicology Letters 173:2, pages 132-139.
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Maria A. Andersson, Kierstin V. Petersson Grawé, Oskar M. Karlsson, Lilianne A.G. Abramsson-Zetterberg & Björn E. Hellman. (2007) Evaluation of the potential genotoxicity of chromium picolinate in mammalian cells in vivo and in vitro. Food and Chemical Toxicology 45:7, pages 1097-1106.
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Makoto Hayashi, James T. MacGregor, David G. Gatehouse, David H. Blakey, Stephen D. Dertinger, Lilianne Abramsson-Zetterberg, Gopala Krishna, Takeshi Morita, Antonella Russo, Norihide Asano, Hiroshi Suzuki, Wakako Ohyama & Dave Gibson. (2007) In vivo erythrocyte micronucleus assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 627:1, pages 10-30.
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Lilianne Abramsson-Zetterberg, Jennie Wong & Nils-Gunnar Ilbäck. (2005) Acrylamide tissue distribution and genotoxic effects in a common viral infection in mice. Toxicology 211:1-2, pages 70-76.
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Jan Grawé, Johannes Biko, Reinhard Lorenz, Christoph Reiners, Helga Stopper, Stanislav Vershenya, Vladimir Vukicevic & Klaus Hempel. (2005) Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 583:1, pages 12-25.
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Lilianne Abramsson-Zetterberg & Kettil Svensson. (2005) Semicarbazide is not genotoxic in the flow cytometry-based micronucleus assay in vivo. Toxicology Letters 155:2, pages 211-217.
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T. Husøy, L. Abramsson-Zetterberg, H.B. Ølstørn, J.E. Paulsen & J. Alexander. (2005) Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 580:1-2, pages 111-118.
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Louise J.K. Durling & Lilianne Abramsson-Zetterberg. (2005) A comparison of genotoxicity between three common heterocyclic amines and acrylamide. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 580:1-2, pages 103-110.
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Nao Kagawa, Masahiko Shimura, Akinori Takai, Satoru Endo & Kazuo Fujikawa. (2004) Relative biological effectiveness of fission neutrons for induction of micronucleus formation in mouse reticulocytes in vivo. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 556:1-2, pages 93-99.
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Lilianne Abramsson-Zetterberg. (2003) The dose-response relationship at very low doses of acrylamide is linear in the flow cytometer-based mouse micronucleus assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 535:2, pages 215-222.
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Lilianne Abramsson-Zetterberg & Premysl Slanina. (2002) Macrocyclic musk compounds—an absence of genotoxicity in the Ames test and the in vivo Micronucleus assay. Toxicology Letters 135:1-2, pages 155-163.
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L. Abramsson-Zetterberg & J. Grawé. (2001) Extended exposure of adult and fetal mice to 50 Hz magnetic field does not increase the incidence of micronuclei in erythrocytes. Bioelectromagnetics 22:5, pages 351-357.
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Karen J Sorensen, Lilianne Abramsson Zetterberg, David O Nelson, Jan Grawe & James D Tucker. (2000) The in vivo dose rate effect of chronic gamma radiation in mice: translocation and micronucleus analyses. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 457:1-2, pages 125-136.
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Polly Y Chang, Dorothea Torous, Louise Lutze-Mann & Richard Winegar. (2000) Impact of p53 status on heavy-ion radiation-induced micronuclei in circulating erythrocytes. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466:1, pages 87-96.
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Lilianne Abramsson-Zetterberg, G�sta Zetterberg, Michael Bergqvist & Jan Graw�. (2000) Human cytogenetic biomonitoring using flow-cytometric analysis of micronuclei in transferrin-positive immature peripheral blood reticulocytes. Environmental and Molecular Mutagenesis 36:1, pages 22-31.
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P. Morales-Ramírez & T. Vallarino-Kelly. (1999) Relationship between the kinetics of micronuclei induction and the mechanism of chromosome break formation by methylnitrosourea in mice in vivo. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 427:1, pages 31-38.
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Lilianne Abramsson-Zetterberg, Jan Grawé & Gösta Zetterberg. (1999) The micronucleus test in rat erythrocytes from bone marrow, spleen and peripheral blood: the response to low doses of ionizing radiation, cyclophosphamide and vincristine determined by flow cytometry. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 423:1-2, pages 113-124.
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Jan Grawé, Lilianne Abramsson-Zetterberg & Gösta Zetterberg. (1998) Low dose effects of chemicals as assessed by the flow cytometric in vivo micronucleus assay. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 405:2, pages 199-208.
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James D. Tucker, Karen J. Sorensen, Cathy S. Chu, David O. Nelson, Marilyn J. Ramsey, Cesare Urlando & John A. Heddle. (1998) The accumulation of chromosome aberrations and Dlb-1 mutations in mice with highly fractionated exposure to gamma radiation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 400:1-2, pages 321-335.
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Lilianne Abramsson-Zetterberg, Jan Grawé & Gösta Zetterberg. (1997) Erythropoiesis and the induction of micronuclei in mouse spleen determined by flow cytometry. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 394:1-3, pages 17-28.
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Lilianne Abramsson-Zetterberg, Jan Grawé & Gösta Zetterberg. (1997) Spontaneous and radiation-induced micronuclei in erythrocytes from four species of wild rodents: a comparison with CBA mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 393:1-2, pages 55-71.
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Lilianne Abramsson-Zetterberg, Gösta Zetterberg & Jan Grawé. (1996) The time-course of micronucleated polychromatic erythrocytes in mouse bone marrow and peripheral blood. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 350:2, pages 349-358.
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Anders Johannisson, Jan Graw�, Agnar Nilsson, Britt-Marie Svedenst�l & Herman Amn�us. (1995) Flow-cytometric identification and follow-up of mice exposed to x-irradiation: Evaluation of a model system. Radiation and Environmental Biophysics 34:3, pages 161-168.
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