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International Journal of Radiation Biology Volume 67, 1995 - Issue 1
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Original Article

Haematopoietic Radioprotection by Cremophor EL: A Polyethoxylated Castor Oil

I. Bertoncello Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag No. 1, A'Beckett Street, Melbourne, Victoria, 3000, Australia
,
A.B. Kriegler Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag No. 1, A'Beckett Street, Melbourne, Victoria, 3000, Australia
,
D.M. Woodcock Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag No. 1, A'Beckett Street, Melbourne, Victoria, 3000, Australia
,
B. Williams Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag No. 1, A'Beckett Street, Melbourne, Victoria, 3000, Australia
,
L. Barber Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag No. 1, A'Beckett Street, Melbourne, Victoria, 3000, Australia
&
S.K. Nilsson Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag No. 1, A'Beckett Street, Melbourne, Victoria, 3000, Australia
Pages 57-64 | Received 02 Nov 1993, Accepted 18 Sep 1994, Published online: 03 Jul 2009

Citations (18)

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Joseph F. Weiss & Michael R. Landauer. (2009) History and development of radiation-protective agents. International Journal of Radiation Biology 85:7, pages 539-573.
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Thomas A. Davis, Ognoon Mungunsukh, Stephen Zins, Regina M. Day & Michael R. Landauer. (2008) Genistein induces radioprotection by hematopoietic stem cell quiescence. International Journal of Radiation Biology 84:9, pages 713-726.
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Thomas A. Davis, Tara K. Clarke, Steven R. Mog & Michael R. Landauer. (2007) Subcutaneous administration of genistein prior to lethal irradiation supports multilineage, hematopoietic progenitor cell recovery and survival. International Journal of Radiation Biology 83:3, pages 141-151.
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G. GUENECHEA. (1997) AM218, a new polyanionic polysaccharide, induces radioprotection in mice when administered shortly before irradiation. International Journal of Radiation Biology 71:1, pages 101-108.
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Articles from other publishers (14)

Tim Ruhl, Gabriele Storti & Norbert Pallua. (2018) Proliferation, Metabolic Activity, and Adipogenic Differentiation of Human Preadipocytes Exposed to 2 Surfactants In Vitro. Journal of Pharmaceutical Sciences 107:5, pages 1408-1415.
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Regina M. DAY, Michal BARSHISHAT-KUPPER, Steven R. MOG, Elizabeth A. MCCART, P. G. S. PRASANNA, Thomas A. DAVIS & Michael R. LANDAUER. (2008) Genistein Protects Against Biomarkers of Delayed Lung Sequelae in Mice Surviving High-Dose Total Body Irradiation. Journal of Radiation Research 49:4, pages 361-372.
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Sherene Loi, Danny Rischin, Michael Michael, Kally Yuen, Kerrie H. Stokes, Andrew G. Ellis, Michael J. Millward & Lorraine K. Webster. (2004) A randomized cross-over trial to determine the effect of Cremophor EL on the pharmacodynamics and pharmacokinetics of carboplatin chemotherapy. Cancer Chemotherapy and Pharmacology 54:5, pages 407-414.
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Marco B. Polee, Alex Sparreboom, Ferry A. L. M. Eskens, Ronald Hoekstra, Jacqueline van de Schaaf, Jaap Verweij, Gerrit Stoter & Ate van der Gaast. (2004) A Phase I and Pharmacokinetic Study of Weekly Paclitaxel and Carboplatin in Patients with Metastatic Esophageal Cancer. Clinical Cancer Research 10:6, pages 1928-1934.
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Sylvia S. W. Ng, William D. Figg & Alex Sparreboom. (2004) Taxane-Mediated Antiangiogenesis in Vitro . Cancer Research 64:3, pages 821-824.
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Michael R. Landauer, Venkataraman Srinivasan & Thomas M. Seed. (2003) Genistein treatment protects mice from ionizing radiation injury. Journal of Applied Toxicology 23:6, pages 379-385.
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Evangelos Briasoulis, Vasilis Karavasilis, Eleftheria Tzamakou, Constantina Haidou, Christina Piperidou & Nicholas Pavlidis. (2002) Pharmacodynamics of non-break weekly paclitaxel (Taxol) and pharmacokinetics of Cremophor-EL vehicle: results of a dose-escalation study. Anti-Cancer Drugs 13:5, pages 481-489.
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H Gelderblom, W.J Loos, J Verweij, M.E.L van der Burg, M.J.A de Jonge, E Brouwer, K Nooter, G Stoter & A Sparreboom. (2002) Modulation of cisplatin pharmacodynamics by Cremophor EL. European Journal of Cancer 38:1, pages 205-213.
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H Gelderblom, J Verweij, K Nooter & A Sparreboom. (2001) Cremophor EL. European Journal of Cancer 37:13, pages 1590-1598.
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Lia van Zuylen, Jaap Verweij & Alex Sparreboom. (2001) Role of Formulation Vehicles in Taxane Pharmacology. Investigational New Drugs 19:2, pages 125-141.
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Laila A. Ramadan, Samia A. Shouman, Mohamed M. Sayed-Ahmed & Ola H. El-Habit. (2001) Modulation of radiation-induced organs toxicity by cremophor-el in experimental animals. Pharmacological Research 43:2, pages 185-191.
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M. R. Landauer, C. A. Castro, K. A. Benson, J. B. Hogan & J. F. Weiss. (2001) Radioprotective and locomotor responses of mice treated with nimodipine alone and in combination with WR‐151327. Journal of Applied Toxicology 21:1, pages 25-31.
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Lorraine K Webster, David M Woodcock, Danny Rischin & Michael J Millward. (2016) Review : Cremophor: Pharmacological activity of an "inert" solubiliser. Journal of Oncology Pharmacy Practice 3:4, pages 186-192.
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A.I. de Vos, K. Nooter, J. Verweij, W.J. Loos, E. Brouwer, P. de Bruijn, E.J. Ruijgrok, M.E.L. van der Burg, G. Stoter & A. Sparreboom. (1997) Differential modulation of cisplatin accumulation in leukocytes and tumor cell lines by the paclitaxel vehicle Cremophor EL. Annals of Oncology 8:11, pages 1145-1150.
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