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Original Article

Flow Cytometric Analysis of Micronuclei in the CD2 ± Subpopulation of Human Lymphocytes Enriched by Magnetic Separation

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Pages 193-202 | Received 18 Apr 1994, Accepted 27 Sep 1994, Published online: 03 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Vanessa Valdiglesias, Blanca Laffon, Eduardo Pásaro & Josefina Méndez. (2011) Evaluation of Okadaic Acid-Induced Genotoxicity in Human Cells Using the Micronucleus Test and γH2AX Analysis. Journal of Toxicology and Environmental Health, Part A 74:15-16, pages 980-992.
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W. BOCKER, C. STREFFER, W.-U. MULLER and C. YU. (1996) Technical report Automated scoring of micronuclei in binucleated human lymphocytes. International Journal of Radiation Biology 70:5, pages 529-537.
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Articles from other publishers (16)

Azeddine Elhajouji & Pascal Stadelmann. 2019. Genotoxicity Assessment. Genotoxicity Assessment 165 193 .
Blanca Laffon, Francisco Aguilera, Julia Ríos-Vázquez, Vanessa Valdiglesias & Eduardo Pásaro. (2014) Follow-up study of genotoxic effects in individuals exposed to oil from the tanker Prestige, seven years after the accident. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 760, pages 10-16.
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Azeddine Elhajouji & Magdalena Lukamowicz-Rajska. 2013. Genotoxicity Assessment. Genotoxicity Assessment 209 235 .
Magdalena Lukamowicz‐Rajska, Micheline Kirsch‐Volders, Willi Suter, Hansjoerg Martus & Azeddine Elhajouji. (2012) Miniaturized flow cytometry‐based in vitro primary human lymphocyte micronucleus assay—validation study. Environmental and Molecular Mutagenesis 53:4, pages 260-270.
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M. Lukamowicz, M. Kirsch-Volders, W. Suter & A. Elhajouji. (2011) In vitro primary human lymphocyte flow cytometry based micronucleus assay: simultaneous assessment of cell proliferation, apoptosis and MN frequency. Mutagenesis 26:6, pages 763-770.
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Micheline Kirsch-Volders, Gina Plas, Azeddine Elhajouji, Magdalena Lukamowicz, Laetitia Gonzalez, Kim Vande Loock & Ilse Decordier. (2011) The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance. Archives of Toxicology 85:8, pages 873-899.
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Magdalena Lukamowicz, Katherine Woodward, Micheline Kirsch-Volders, Willi Suter & Azeddine Elhajouji. (2011) A flow cytometry based in vitro micronucleus assay in TK6 cells-Validation using early stage pharmaceutical development compounds. Environmental and Molecular Mutagenesis 52:5, pages 363-372.
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Steven M. Bryce, Svetlana L. Avlasevich, Jeffrey C. Bemis, Magdalena Lukamowicz, Azeddine Elhajouji, Freddy Van Goethem, Marlies De Boeck, Dominiek Beerens, Hilde Aerts, Jacky Van Gompel, Joanne E. Collins, Patricia C. Ellis, Angela T. White, Anthony M. Lynch & Stephen D. Dertinger. (2008) Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 650:2, pages 181-195.
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Steven M. Bryce, Jeffrey C. Bemis, Svetlana L. Avlasevich & Stephen D. Dertinger. (2007) In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 630:1-2, pages 78-91.
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Svetlana L. Avlasevich, Steven M. Bryce, Siân E. Cairns & Stephen D. Dertinger. (2006) In vitro micronucleus scoring by flow cytometry: Differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability. Environmental and Molecular Mutagenesis 47:1, pages 56-66.
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M. Suggitt, J. Fearnley, D.J. Swaine, M. Volpato, R.M. Phillips, M.C. Bibby, P.M. Loadman & D. Anderson. (2003) Comet assay and flow cytometry analysis of DNA repair in normal and cancer cells treated with known mutagens with different mechanisms of action. Teratogenesis, Carcinogenesis, and Mutagenesis 23:S2, pages 13-29.
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Carmela Fimognari, Michael N�sse & Patrizia Hrelia. (1999) Flow cytometric analysis of genetic damage, effect on cell cycle progression, and apoptosis by thiophanate-methyl in human lymphocytes. Environmental and Molecular Mutagenesis 33:2, pages 173-176.
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Danielle Roman, Franziska Locher, Willi Suter, André Cordier & Maria Bobadilla. (1998) Evaluation of a new procedure for the flow cytometric analysis of in vitro, chemically induced micronuclei in V79 cells. Environmental and Molecular Mutagenesis 32:4, pages 387-396.
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Michael Nüsse & Kristin Marx. (1997) Flow cytometric analysis of micronuclei in cell cultures and human lymphocytes: advantages and disadvantages. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 392:1-2, pages 109-115.
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Wolfgang-Ulrich Müller, Michael Nüsse, Beate M. Miller, Anne Slavotinek, Silvia Viaggi & Christian Streffer. (1996) Micronuclei: a biological indicator of radiation damage. Mutation Research/Reviews in Genetic Toxicology 366:2, pages 163-169.
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Jurina M. Wessels & Michael Nüsse. (2005) Flow cytometric detection of micronuclei by combined staining of DNA and membranes. Cytometry 19:3, pages 201-208.
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