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Research Article

Detection and evaluation of chromosomal aberrations induced by high doses of-irradiation using immunogold-silver painting of prematurely condensed chromosomes

Pages 517-520 | Published online: 03 Jul 2009

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Usha Yadav, Nagesh Nagabhushana Bhat, Kapil Bansidhar Shirsath, Utkarsha Sagar Mungse & Balvinder Kaur Sapra. (2020) Multifaceted applications of pre-mature chromosome condensation in radiation biodosimetry. International Journal of Radiation Biology 96:10, pages 1274-1280.
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Justyna Miszczyk & Kamila Rawojć. (2020) Effects of culturing technique on human peripheral blood lymphocytes response to proton and X-ray radiation. International Journal of Radiation Biology 96:4, pages 424-433.
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Yuichi Kanasugi, Nobuyuki Hamada, Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Takehiko Kakizaki, Yasuhiko Kobayashi & Kaoru Takakura. (2007) Role of DNA-PKcs in the bystander effect after low- or high-LET irradiation. International Journal of Radiation Biology 83:2, pages 73-80.
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Articles from other publishers (30)

Eisuke Gotoh. 2023. Chromosome Analysis. Chromosome Analysis 41 51 .
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Roel Quintens, Sarah Baatout & Marjan Moreels. 2020. Stress Challenges and Immunity in Space. Stress Challenges and Immunity in Space 519 533 .
Eisuke Gotoh. 2019. Radiation Cytogenetics. Radiation Cytogenetics 47 60 .
Xue Lu, Hua Zhao, Jiang-Bin Feng, Xiao-Tao Zhao, De-Qing Chen & Qing-Jie Liu. (2016) Dose response of multiple parameters for calyculin A-induced premature chromosome condensation in human peripheral blood lymphocytes exposed to high doses of cobalt-60 gamma-rays. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 807, pages 47-54.
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Sangeeta Dutta, M.H. Yashavarddhan, Nitya Nand Srivastava, Rajiv Ranjan, Sania Bajaj, Bhargab Kalita, Abhinav Singh, Swaran J.S. Flora & Manju Lata Gupta. (2016) Countering effects of a combination of podophyllotoxin, podophyllotoxin β-D-glucoside and rutin hydrate in minimizing radiation induced chromosomal damage, ROS and apoptosis in human blood lymphocytes. Food and Chemical Toxicology 91, pages 141-150.
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Eisuke Gotoh. 2015. Chromatin Protocols. Chromatin Protocols 53 66 .
Rupak Pathak & Pataje G. S. Prasanna. 2014. Molecular Toxicology Protocols. Molecular Toxicology Protocols 171 181 .
I. Romero, O. Garcia, A. I. Lamadrid, E. Gregoire, J. E. Gonzalez, W. Morales, C. Martin, J.-F. Barquinero & P. Voisin. (2013) Assessment of simulated high-dose partial-body irradiation by PCC-R assay. Journal of Radiation Research 54:5, pages 863-871.
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Roser Puig, Leonardo Barrios, Mònica Pujol, Maria Rosa Caballín & Joan-Francesc Barquinero. (2013) Suitability of scoring PCC rings and fragments for dose assessment after high-dose exposures to ionizing radiation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 757:1, pages 1-7.
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Marjan Moreels, Roel Quintens & Sarah Baatout. 2012. Stress Challenges and Immunity in Space. Stress Challenges and Immunity in Space 345 356 .
Tomisato Miura & William F. Blakely. (2011) Optimization of calyculin A-induced premature chromosome condensation assay for chromosome aberration studies. Cytometry Part A 79A:12, pages 1016-1022.
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Sreedevi Balakrishnan, kapil Shirsath, Nagesh Bhat & Kshiti Anjaria. (2010) Biodosimetry for high dose accidental exposures by drug induced premature chromosome condensation (PCC) assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 699:1-2, pages 11-16.
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Carita Lindholm, Daniela Stricklin, Alicja Jaworska, Armi Koivistoinen, Wendla Paile, Eva Arvidsson, Joanna Deperas-Standylo & Andrzej Wojcik. (2010) Premature Chromosome Condensation (PCC) Assay for Dose Assessment in Mass Casualty Accidents. Radiation Research 173:1, pages 71-78.
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Z.Z. Wang, W.J. Li, D.J. Zhi, Q.X. Gao, Y. Qu & B.Q. Wang. (2009) Prematurely condensed chromosome fragments in human lymphocytes induced by high doses of high-linear-energy-transfer irradiation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 679:1-2, pages 9-12.
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Eisuke Gotoh. 2009. Chromatin Protocols. Chromatin Protocols 83 92 .
J.M. Kramer, A. Evans, K. Drury & K. Moore. (2008) Calyculin-A improves chromosome condensation for cytogenetic analysis of blastomeres from bovine and murine eight-cell stage embryos. Theriogenology 70:4, pages 692-703.
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Eisuke Gotoh, Aya Funada, Mayumi Mohri, Ryonfa Lee & Kaoru Takakura. (2008) High yields of isochromatid breaks and successive formation of chromosome exchanges may lead to reproductive cell death following high-LET irradiation. Open Life Sciences 3:2, pages 121-133.
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Eisuke Gotoh. (2007) Visualizing the dynamics of chromosome structure formation coupled with DNA replication. Chromosoma 116:5, pages 453-462.
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Z. Z. Wang, W. J. Li, D. J. Zhi, X. G. Jing, W. Wei, Q. X. Gao & B. Liu. (2007) Biodosimetry estimate for high-LET irradiation. Radiation and Environmental Biophysics 46:3, pages 229-235.
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Ana I. LAMADRID, Omar GARCÍA, Martine DELBOS, Philippe VOISIN & Laurence ROY. (2007) PCC-ring Induction in Human Lymphocytes Exposed to Gamma and Neutron Irradiation. Journal of Radiation Research 48:1, pages 1-6.
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Eisuke Gotoh & Marco Durante. (2006) Chromosome condensation outside of mitosis: Mechanisms and new tools. Journal of Cellular Physiology 209:2, pages 297-304.
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William F. Blakely, Charles A. Salter & Pataje G.S. Prasanna. (2005) EARLY-RESPONSE BIOLOGICAL DOSIMETRY???RECOMMENDED COUNTERMEASURE ENHANCEMENTS FOR MASS-CASUALTY RADIOLOGICAL INCIDENTS AND TERRORISM. Health Physics 89:5, pages 494-504.
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Malgorzata I. Srebniak, Gizela G. Trapp, Angelika K. Wawrzkiewicz, Wojciech Kaźmierczak & Andrzej K. Wiczkowski. (2016) The Usefulness of Calyculin A for Cytogenetic Prenatal Diagnosis. Journal of Histochemistry & Cytochemistry 53:3, pages 391-394.
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Tetsuya Kawata, Hisao Ito, Kerry George, Honglu Wu & Francis A. Cucinotta. (2004) Chromosome Aberrations Induced by High-LET Radiations. Biological Sciences in Space 18:4, pages 216-223.
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Masao Suzuki, Chang-qing Piao, Eric J. Hall & Tom K. Hei. (2001) Cell Killing and Chromatid Damage in Primary Human Bronchial Epithelial Cells Irradiated with Accelerated 56 Fe Ions . Radiation Research 155:3, pages 432-439.
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Pataje G.S Prasanna, Nestor D Escalada & William F Blakely. (2000) Induction of premature chromosome condensation by a phosphatase inhibitor and a protein kinase in unstimulated human peripheral blood lymphocytes: a simple and rapid technique to study chromosome aberrations using specific whole-chromosome DNA hybridization probes for biological dosimetry. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466:2, pages 131-141.
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REIKO KANDA. (2000) Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry. Journal of Radiation Research 41:1, pages 1-8.
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S. Ghosh, N. Paweletz & D. Schroeter. (1998) Cdc2-Independent Induction of Premature Mitosis by Okadaic Acid in HeLa Cells. Experimental Cell Research 242:1, pages 1-9.
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