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Research Article

Low dose-rate fibroblast radiosensitivity and the prediction of patient response to radiotherapy

Pages 289-300 | Published online: 03 Jul 2009

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D. Słonina, M. Klimek, T. Szpytma, A. Gasinska. (2000) Comparison of the radiosensitivity of normal-tissue cells with normal-tissue reactions after radiotherapy. International Journal of Radiation Biology 76:9, pages 1255-1264.
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C. CATENA, P. PARASACCHI, D. CONTI, A. SGURA, G. TRENTA, E. RIGHI, M. M. TRINCI and M. TRINCI. (1997) Peripheral blood lymphocyte decrease and micronucleus yields during radiotherapy. International Journal of Radiation Biology 72:5, pages 575-585.
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Reem H. EL-Gebaly, Monira M. Rageh & Islam K. Maamoun. (2019) Radio-protective potential of lipoic acid free and nano-capsule against 99mTc-MIBI induced injury in cardio vascular tissue. Journal of X-Ray Science and Technology 27:1, pages 83-96.
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Sarah L. Kerns, Kuang-Hsiang Chuang, William Hall, Zachary Werner, Yuhchyau Chen, Harry Ostrer, Catharine West & Barry Rosenstein. (2018) Radiation biology and oncology in the genomic era. The British Journal of Radiology 91:1091, pages 20170949.
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Pamela Sinha, Kantha D. Arunachalam & Sathesh Kumar Annamalai. (2018) Radio-protective dosimetry of Pangasius sutchi as a biomarker, against gamma radiation dosages perceived by genotoxic assays. Ecotoxicology and Environmental Safety 164, pages 629-640.
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Farideh Koohian, Ahmad Shanei, Daryoush Shahbazi-Gahrouei, Seyed Hossein Hejazi & Mohammad-Taghi Moradi. (2017) The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by γ-Irradiation in Mice Blood Lymphocytes. Dose-Response 15:2, pages 155932581770569.
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Pedro Carlos Lara, Jesús Joaquín López-Peñalver, Virgínea de Araújo Farias, M. Carmen Ruiz-Ruiz, Francisco Javier Oliver & José Mariano Ruiz de Almodóvar. (2015) Direct and bystander radiation effects: A biophysical model and clinical perspectives. Cancer Letters 356:1, pages 5-16.
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Sarah L Kerns, Catharine M L West, C Nicolaj Andreassen, Gillian C Barnett, Søren M Bentzen, Neil G Burnet, Andre Dekker, Dirk De Ruysscher, Alison Dunning, Matthew Parliament, Chris Talbot, Ana Vega & Barry S Rosenstein. (2014) Radiogenomics: the search for genetic predictors of radiotherapy response. Future Oncology 10:15, pages 2391-2406.
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Nilufer Cinkilic, Ece Tüzün, Sibel Kahraman Çetintaş, Özgür Vatan, Dilek Yılmaz, Tolga Çavaş, Sema Tunç, Lütfi Özkan & Rahmi Bilaloğlu. (2014) Radio-protective effect of cinnamic acid, a phenolic phytochemical, on genomic instability induced by X-rays in human blood lymphocytes in vitro. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 770, pages 72-79.
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M.L.K. Chua & K. Rothkamm. (2013) Biomarkers of Radiation Exposure: Can They Predict Normal Tissue Radiosensitivity?. Clinical Oncology 25:10, pages 610-616.
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Nilufer Cinkilic, Sibel Kahraman Cetintas, Tolga Zorlu, Ozgur Vatan, Dilek Yilmaz, Tolga Cavas, Sema Tunc, Lutfi Ozkan & Rahmi Bilaloglu. (2013) Radioprotection by two phenolic compounds: Chlorogenic and quinic acid, on X-ray induced DNA damage in human blood lymphocytes in vitro. Food and Chemical Toxicology 53, pages 359-363.
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Paul F. Wilson, Hatsumi Nagasawa, Christy L. Warner, Markus M. Fitzek, John B. Little & Joel S. Bedford. (2008) Radiation Sensitivity of Primary Fibroblasts from Hereditary Retinoblastoma Family Members and Some Apparently Normal Controls: Colony Formation Ability during Continuous Low-Dose-Rate Gamma Irradiation. Radiation Research 169:5, pages 483-494.
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Sheikh M. Ismail, Monica Puppi, Sheela Prithivirajsingh, Anupama Munshi, Uma Raju, Raymond E. Meyn, Thomas A. Buchholz, Michael D. Story, William A. Brock, Luka Milas, Howard D. Thames & Craig W. Stevens. (2004) Predicting Radiosensitivity Using DNA End-Binding Complex Analysis. Clinical Cancer Research 10:4, pages 1226-1234.
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Tung-Kwang Lee, Ron R Allison, Kevin F O’Brien, Roberta M Johnke, Karen I Christie, James L Naves, Charles J Kovacs, Hyder Arastu & Ulf L Karlsson. (2003) Lymphocyte radiosensitivity correlated with pelvic radiotherapy morbidity. International Journal of Radiation Oncology*Biology*Physics 57:1, pages 222-229.
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Maria Widel, Sylwia Jedrus, Beata Lukaszczyk, Katarzyna Raczek-Zwierzycka & Andrzej Swierniak. (2003) Radiation-Induced Micronucleus Frequency in Peripheral Blood Lymphocytes is Correlated with Normal Tissue Damage in Patients with Cervical Carcinoma Undergoing Radiotherapy. Radiation Research 159:6, pages 713-721.
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Kerstin Borgmann, Barbara Röper, Rafaat Abd El-Awady, Sophie Brackrock, Maika Bigalke, Tilo Dörk, Winfried Alberti, Ekkehard Dikomey & Jochen Dahm-Daphi. (2002) Indicators of late normal tissue response after radiotherapy for head and neck cancer: fibroblasts, lymphocytes, genetics, DNA repair, and chromosome aberrations. Radiotherapy and Oncology 64:2, pages 141-152.
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Gijsbert Peter Raaphorst, Shawn Malone, Ghazi Alsbeih, Louis Souhani, Eva Szumacher & Andre Girard. (2002) Skin fibroblasts in vitro radiosensitivity can predict for late complications following AVM radiosurgery. Radiotherapy and Oncology 64:2, pages 153-156.
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Neil G. Burnet & John H. Peacock. (2002) NORMAL CELLULAR RADIOSENSITIVITY IN AN ADULT FANCONI ANAEMIA PATIENT WITH MARKED CLINICAL RADIOSENSITIVITY (1). Radiotherapy and Oncology 62:3, pages 350-351.
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R.P Hill, H.-P Rodemann, J.H Hendry, S.A Roberts & M.S Anscher. (2001) Normal tissue radiobiology: from the laboratory to the clinic. International Journal of Radiation Oncology*Biology*Physics 49:2, pages 353-365.
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G.P. Raaphorst, S. Malone, J. Szanto & R. Gray. (2000) Severe normal tissue complication correlates with increased in vitro fibroblast radiosensitivity in radical prostate radiotherapy: A case report. International Journal of Cancer 90:6, pages 336-342.
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Ghazi Alsbeih, Shawn Malone, Catherine Lochrin, Andre Girard, Bernard Fertil & G.Peter Raaphorst. (2000) Correlation between normal tissue complications and in vitro radiosensitivity of skin fibroblasts derived from radiotherapy patients treated for variety of tumors. International Journal of Radiation Oncology*Biology*Physics 46:1, pages 143-152.
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A M Eastham, B Marples, A E Kiltie, C J Orton & C M L West. (1999) Fibroblast radiosensitivity measured using the comet DNA-damage assay correlates with clonogenic survival parameters. British Journal of Cancer 79:9-10, pages 1366-1371.
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U Kasten, N Plottner, J Johansen, J Overgaard & E Dikomey. (1999) Ku70/80 gene expression and DNA-dependent protein kinase (DNA-PK) activity do not correlate with double-strand break (dsb) repair capacity and cellular radiosensitivity in normal human fibroblasts. British Journal of Cancer 79:7-8, pages 1037-1041.
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R.I. Mackay & J.H. Hendry. (1999) The modelled benefits of individualizing radiotherapy patients’ dose using cellular radiosensitivity assays with inherent variability. Radiotherapy and Oncology 50:1, pages 67-75.
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Neil G. Burnet, Jørgen Johansen, Ingela Turesson, Jan Nyman & John H. Peacock. (1998) Describing patients' normal tissue reactions: Concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity. International Journal of Cancer 79:6, pages 606-613.
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Carsten Herskind, Søren M Bentzen, Jens Overgaard, Marie Overgaard, Michael Bamberg & H.Peter Rodemann. (1998) Differentiation state of skin fibroblast cultures versus risk of subcutaneous fibrosis after radiotherapy. Radiotherapy and Oncology 47:3, pages 263-269.
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