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Research Article

Abrogation of P53 function by transfection of HPV16 E6 gene does not enhance resistance of human tumour cells to ionizing radiation

Pages 151-160 | Published online: 03 Jul 2009

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Ping-Kun Zhou, Yi Sun & Jing An. (2009) Interaction between viral proteins and hosts and its disturbance in the cellular responses to ionising radiation. International Journal of Radiation Biology 85:7, pages 587-597.
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Zhen Wang, Rong-Hui Xia, Dong-Xia Ye & Jiang Li. (2016) Human Papillomavirus 16 Infection and TP53 Mutation: Two Distinct Pathogeneses for Oropharyngeal Squamous Cell Carcinoma in an Eastern Chinese Population. PLOS ONE 11:10, pages e0164491.
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Claude A. Fischer, Inti Zlobec, Edith Green, Simone Probst, Claudio Storck, Alessandro Lugli, Luigi Tornillo, Markus Wolfensberger & Luigi M. Terracciano. (2009) Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality?. International Journal of Cancer 126:5, pages 1256-1262.
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Kuan-Ting Kuo, Chen-Hsiang Hsiao, Ching-Hung Lin, Lu-Ting Kuo, Shih-Hung Huang & Ming-Chieh Lin. (2008) The biomarkers of human papillomavirus infection in tonsillar squamous cell carcinoma—molecular basis and predicting favorable outcome. Modern Pathology 21:4, pages 376-386.
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William H. Westra, Janis M. Taube, M.L. Poeta, Shanaz Begum, David Sidransky & Wayne M. Koch. (2008) Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck . Clinical Cancer Research 14:2, pages 366-369.
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Carole Fakhry & Maura L. Gillison. (2006) Clinical Implications of Human Papillomavirus in Head and Neck Cancers. Journal of Clinical Oncology 24:17, pages 2606-2611.
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Todd D. Tillmanns, Scott A. Kamelle, Suresh Guruswamy, Natalie S. Gould, Teresa L. Rutledge & Doris M. Benbrook. (2005) Sensitization of cervical cancer cell lines to low-dose radiation by retinoic acid does not require functional p53. Gynecologic Oncology 97:1, pages 142-150.
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Maura L. Gillison. (2004) Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity. Seminars in Oncology 31:6, pages 744-754.
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Timothy M. Pawlik & Khandan Keyomarsi. (2004) Role of cell cycle in mediating sensitivity to radiotherapy. International Journal of Radiation Oncology*Biology*Physics 59:4, pages 928-942.
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Satoshi Tanno, Nobuyuki Yanagawa, Atsuya Habiro, Kazuya Koizumi, Yasuhiro Nakano, Manabu Osanai, Yusuke Mizukami, Toshikatsu Okumura, Joseph R. Testa & Yutaka Kohgo. (2004) Serine/Threonine Kinase AKT Is Frequently Activated in Human Bile Duct Cancer and Is Associated with Increased Radioresistance. Cancer Research 64:10, pages 3486-3490.
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Haimei Huang, Shian‐Yi Huang, Ting‐Ting Chen, Ja‐Chi Chen, Chian‐Ling Chiou & Ter‐Mei Huang. (2004) Cisplatin restores p53 function and enhances the radiosensitivity in HPV16 E6 containing SiHa cells. Journal of Cellular Biochemistry 91:4, pages 756-765.
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Vojko Djukic, Ljiljana JanosevicB.B., Milovan Dimitrijevic, Svetozar DamjanovicS.S., Predrag Pesko & Jelena Dotlic. (2003) Genetic markers for head and neck cancers: Current state of art and perspectives. Jugoslovenska medicinska biohemija Yugoslav Medical Biochemistry 22:4, pages 273-282.
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YU-CHING CHANG, HSUEH-WEI CHANG, CHU-BIN LIAO & YIN-CHANG LIU. (2002) The Roles of p53, DNA Repair, and Oxidative Stress in Ultraviolet C Induction of Proliferating Cell Nuclear Antigen Expression. Annals of the New York Academy of Sciences 973:1, pages 384-391.
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Ruey-Hwang Chou & Haimei Huang. (2002) Restoration of p53 tumor suppressor pathway in human cervical carcinoma cells by sodium arsenite. Biochemical and Biophysical Research Communications 293:1, pages 298-306.
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DAVID H. GORSKI, HELENA J. MAUCERI & RALPH R. WEICHSELBAUM. 2002. Gene Therapy of Cancer. Gene Therapy of Cancer 435 448 .
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Ruey-Hwang Chou & Haimei Huang. (2002) Sodium arsenite suppresses human papillomavirus-16 E6 gene and enhances apoptosis in E6-transfected human lymphoblastoid cells. Journal of Cellular Biochemistry 84:3, pages 615-624.
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Yoshifumi Matsui, Yukihiro Tsuchida & Peter C. Keng. (2001) Effects of p53 Mutations on Cellular Sensitivity to Ionizing Radiation. American Journal of Clinical Oncology 24:5, pages 486-490.
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Katja Lindel, Karl T. Beer, Jean Laissue, Richard H. Greiner & Daniel M. Aebersold. (2001) Human papillomavirus positive squamous cell carcinoma of the oropharynx. Cancer 92:4, pages 805-813.
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Seth R. Schwartz, Bevan Yueh, James K. McDougall, Janet R. Daling & Stephen M. Schwartz. (2016) Human Papillomavirus Infection and Survival in Oral Squamous Cell Cancer: A Population‐Based Study. Otolaryngology–Head and Neck Surgery 125:1, pages 1-9.
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Lynne Hampson, El Said Abd El Hady, James V. Moore, Henry Kitchener & Ian N. Hampson. (2001) The HPV16 E6 and E7 proteins and the radiation resistance of cervical carcinoma. The FASEB Journal 15:8, pages 1445-1447.
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Larry H Thompson & David Schild. (2001) Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 477:1-2, pages 131-153.
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Zhimin Tong, Gurmit Singh & Andrew J. Rainbow. (2000) The Role of the p53 Tumor Suppressor in the Response of Human Cells to Photofrin-mediated Photodynamic Therapy. Photochemistry and Photobiology 71:2, pages 201-210.
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Zhimin Tong, Gurmit Singh & Andrew J. Rainbow. (2000) The Role of the p53 Tumor Suppressor in the Response of Human Cells to Photofrin-mediated Photodynamic Therapy. Photochemistry and Photobiology 71:2, pages 201.
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L Enns, D Murray & R Mirzayans. (1999) Effects of the protein kinase inhibitors wortmannin and KN62 on cellular radiosensitivity and radiation-activated S phase and G1/S checkpoints in normal human fibroblasts. British Journal of Cancer 81:6, pages 959-965.
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Constanze Geiger, Klaus J. Weber & Frederik Wenz. (1999) Radiation induced chromosome aberrations and clonogenic survival in human lymphoblastoid cell lines with different p53 statusBestrahlungsinduzierte chromosomenaberrationen und klonogenes überleben in humanen lymphoblasten mit unterschiedlichen p53-status. Strahlentherapie und Onkologie 175:6, pages 289-292.
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Frank Lohr, Holger Hof, Klaus -Josef Weber, Detlev Latz & Frederik Wenz. (1998) X-Ray induced changes in immunostaining of proliferating cell nuclear antigen (PCNA) in V79 hamster fibroblastsDetektion von PCNA (Proliferating Cell Nuclear Antigen) nach Photonenbestrahlung in V79-Hamsterzellen. Strahlentherapie und Onkologie 174:11, pages 575-579.
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Ruud WiggenraadM.D.M.D., Reinder TammingaM.Sc.M.Sc., Paul BlokM.D.M.D., Remigio RouseM.D.M.D. & Jo HermansPh.D.Ph.D.. (1998) The Prognostic Significance of P53 Expression for Survival and Local Control in Rectal Carcinoma Treated with Surgery and Postoperative Radiotherapy. International Journal of Radiation Oncology*Biology*Physics 41:1, pages 29-35.
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