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Research Article

The ATM gene and the radiobiology of ataxia-telangiectasia

Pages 527-537 | Published online: 03 Jul 2009

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Read on this site (4)

Olga K. Mirzoeva & John H. J. Petrini. (2001) DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex. Molecular and Cellular Biology 21:1, pages 281-288.
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D. W. CHAN, D. P. GATELY, S. URBAN, A. M. GALLOWAY, S. p. LEES-MILLER, T. YEN & J. ALLALUNIS-TURNER. (1998) Lack of correlation between ATM protein expression and tumour cell radiosensitivity. International Journal of Radiation Biology 74:2, pages 217-224.
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N. FORAY, A. PRIESTLEY, G. ALSBEIH, C. BADIE, E. P. CAPULAS, C. F. ARLETT and E. P. MALAISE. (1997) Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks. International Journal of Radiation Biology 72:3, pages 271-283.
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Articles from other publishers (46)

Laura El Nachef, Elise Berthel, Mélanie L. Ferlazzo, Eymeric Le Reun, Joelle Al-Choboq, Juliette Restier-Verlet, Adeline Granzotto, Laurène Sonzogni, Michel Bourguignon & Nicolas Foray. (2022) Cancer and Radiosensitivity Syndromes: Is Impaired Nuclear ATM Kinase Activity the Primum Movens?. Cancers 14:24, pages 6141.
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Jean-Pierre Pouget, Catherine Lozza, Emmanuel Deshayes, Vincent Boudousq & Isabelle Navarro-Teulon. (2015) Introduction to Radiobiology of Targeted Radionuclide Therapy. Frontiers in Medicine 2.
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Rainer Poltz & Michael Naumann. (2012) Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention. BMC Systems Biology 6:1, pages 125.
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Nicolas Foray & Pierre Verrelle. (2011) Réparations et réparatoses : entre modèles moléculaires et réalité clinique. Bulletin du Cancer 98:3, pages 257-275.
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Victoria J. WestonCeri E. OldreiveAnna SkowronskaDavid G. OscierGuy PrattMartin J. S. DyerGraeme SmithJudy E. Powell, Zbigniew Rudzki, Pamela KearnsPaul A. H. MossA. Malcolm R. TaylorTatjana Stankovic. (2010) The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Blood 116:22, pages 4578-4587.
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Jeesun Kim & Paul K.Y. Wong. (2009) Oxidative Stress Is Linked to ERK1/2-p16 Signaling-mediated Growth Defect in ATM-deficient Astrocytes. Journal of Biological Chemistry 284:21, pages 14396-14404.
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Joachim Schneider, Thomas Illig, Albert Rosenberger, Heike Bickeböller & Hans-Erich Wichmann. (2008) Detection of ATM Gene Mutations in Young Lung Cancer Patients: A Population-based Control Study. Archives of Medical Research 39:2, pages 226-231.
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M. John Hicks, Jill R. Roth, Claudia A. Kozinetz & Lisa L. Wang. (2007) Clinicopathologic Features of Osteosarcoma in Patients With Rothmund-Thomson Syndrome. Journal of Clinical Oncology 25:4, pages 370-375.
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Hiroshi YAMAGUCHI, Hiroshi OHARA & Anthony J. WAKER. (2006) A Model for the Induction of DNA Damages and their Evolution into Cell Clonogenic Inactivation. Journal of Radiation Research 47:2, pages 197-211.
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Xiaolin Bi, Min Gong, Deepa Srikanta & Yikang S Rong. (2005) Drosophila ATM and Mre11 Are Essential for the G2/M Checkpoint Induced by Low-Dose Irradiation. Genetics 171:2, pages 845-847.
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Takehiko Nohmi & Ken-ichi Masumura. (2005) Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens. Environmental and Molecular Mutagenesis 45:2-3, pages 150-161.
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Martin Kühne, Enriqueta Riballo, Nicole Rief, Kai Rothkamm, Penny A. Jeggo & Markus Löbrich. (2004) A Double-Strand Break Repair Defect in ATM-Deficient Cells Contributes to Radiosensitivity. Cancer Research 64:2, pages 500-508.
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Tetsuya Kawata, Hisao Ito, Kerry George, Honglu Wu, Takashi Uno, Kouichi Isobe & Francis A. Cucinotta. (2003) Radiation-Induced Chromosome Aberrations in Ataxia Telangiectasia Cells: High Frequency of Deletions and Misrejoining Detected by Fluorescence In Situ Hybridization . Radiation Research 159:5, pages 597-603.
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Kerstin Borgmann, Barbara Röper, Rafaat Abd El-Awady, Sophie Brackrock, Maika Bigalke, Tilo Dörk, Winfried Alberti, Ekkehard Dikomey & Jochen Dahm-Daphi. (2002) Indicators of late normal tissue response after radiotherapy for head and neck cancer: fibroblasts, lymphocytes, genetics, DNA repair, and chromosome aberrations. Radiotherapy and Oncology 64:2, pages 141-152.
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A R Gennery, A J Cant & P A Jeggo. (2000) Immunodeficiency associated with DNA repair defects. Clinical and Experimental Immunology 121:1, pages 1-7.
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Qishen PangTracy A. ChristiansonWinifred KeebleJane DiazGregory R. FaulknerCarol ReifsteckSusan OlsonGrover C. Bagby. (2001) The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality. Blood 98:5, pages 1392-1401.
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Yu-Quan Shi, Ling Li, Oezden Sanal, Ilhan Tezcan, Gillian C Emery, Hans Blattmann & Nigel E.A Crompton. (2001) High levels of delayed radiation-induced apoptosis observed in lymphoblastoid cell lines from ataxia-telangiectasia patients. International Journal of Radiation Oncology*Biology*Physics 49:2, pages 555-559.
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Grant S Stewart, Richard S Maser, Tanja Stankovic, Debra A Bressan, Mark I Kaplan, Nikolaas G.J Jaspers, Anja Raams, Philip J Byrd, John H.J Petrini & A.Malcolm R Taylor. (1999) The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder. Cell 99:6, pages 577-587.
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Maria E. Cardenas, M. Cristina Cruz, Maurizio Del Poeta, Namjin Chung, John R. Perfect & Joseph Heitman. (1999) Antifungal Activities of Antineoplastic Agents: Saccharomyces cerevisiae as a Model System To Study Drug Action . Clinical Microbiology Reviews 12:4, pages 583-611.
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Claire Alapetite, Pierre Thirion, Anne de la Rochefordi�re, Jean-Marc Cosset & Ethel Moustacchi. (1999) Analysis by alkaline comet assay of cancer patients with severe reactions to radiotherapy: Defective rejoining of radioinduced dna strand breaks in lymphocytes of breast cancer patients. International Journal of Cancer 83:1, pages 83-90.
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