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Research Article

Dose-rate effect on radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line

Pages 241-249 | Published online: 03 Jul 2009

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Mélanie Ferlazzo, Elise Berthel, Adeline Granzotto, Clément Devic, Laurène Sonzogni, Jean-Thomas Bachelet, Sandrine Pereira, Michel Bourguignon, Alain Sarasin, Mauro Mezzina & Nicolas Foray. (2020) Some mutations in the xeroderma pigmentosum D gene may lead to moderate but significant radiosensitivity associated with a delayed radiation-induced ATM nuclear localization. International Journal of Radiation Biology 96:3, pages 394-410.
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Juliette Restier-Verlet, Aurélie Joubert, Mélanie L. Ferlazzo, Adeline Granzotto, Laurène Sonzogni, Joëlle Al-Choboq, Laura El Nachef, Eymeric Le Reun, Michel Bourguignon & Nicolas Foray. (2023) X-rays-Induced Bystander Effect Consists in the Formation of DNA Breaks in a Calcium-Dependent Manner: Influence of the Experimental Procedure and the Individual Factor. Biomolecules 13:3, pages 542.
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Juliette Restier-Verlet, Michel Drouet, Pauline Pras, Mélanie L. Ferlazzo, Adeline Granzotto, Laurène Sonzogni, Joëlle Al-Choboq, Laura El Nachef, Sabine François, Michel Bourguignon & Nicolas Foray. (2023) Molecular Influence of the ATM Protein in the Treatment of Human Cells with Different Radioprotective Drugs: Comparisons between Antioxidative and Pro-Episkevic Strategies. Biomolecules 13:3, pages 524.
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Arnaud Beddok, Chloé Lahaye, Valentin Calugaru, Ludovic De Marzi, Charles Fouillade, Samuel Salvador, Jean-Marc Fontbonne, Vincent Favaudon & Juliette Thariat. (2022) A Comprehensive Analysis of the Relationship Between Dose Rate and Biological Effects in Preclinical and Clinical Studies, From Brachytherapy to Flattening Filter Free Radiation Therapy and FLASH Irradiation. International Journal of Radiation Oncology*Biology*Physics 113:5, pages 985-995.
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Laurène Sonzogni, Mélanie L. Ferlazzo, Adeline Granzotto, Béatrice Fervers, Laurent Charlet & Nicolas Foray. (2022) DNA Double-Strand Breaks Induced in Human Cells by 6 Current Pesticides: Intercomparisons and Influence of the ATM Protein. Biomolecules 12:2, pages 250.
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Muriel Viau, Laurène Sonzogni, Mélanie L. Ferlazzo, Elise Berthel, Sandrine Pereira, Larry Bodgi, Adeline Granzotto, Clément Devic, Béatrice Fervers, Laurent Charlet & Nicolas Foray. (2021) DNA Double-Strand Breaks Induced in Human Cells by Twelve Metallic Species: Quantitative Inter-Comparisons and Influence of the ATM Protein. Biomolecules 11:10, pages 1462.
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Ghazi Alsbeih, Najla Al-Harbi, Sheikh Ismail & Michael Story. (2021) Impaired DNA Repair Fidelity in a Breast Cancer Patient With Adverse Reactions to Radiotherapy. Frontiers in Public Health 9.
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Mira Maalouf, Adeline Granzotto, Clément Devic, Larry Bodgi, Mélanie Ferlazzo, Christophe Peaucelle, Marcel Bajard, Jean-Yves Giraud, Jacques Balosso, Joël Hérault, Marie-Claude Biston, Claude Malet & Nicolas Foray. (2019) Influence of Linear Energy Transfer on the Nucleo-shuttling of the ATM Protein: A Novel Biological Interpretation Relevant for Particles and Radiation. International Journal of Radiation Oncology*Biology*Physics 103:3, pages 709-718.
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Mélanie L. Ferlazzo, Mohamed Kheir Eddine Bach-Tobdji, Amar Djerad, Laurène Sonzogni, Clément Devic, Adeline Granzotto, Larry Bodgi, Jean-Thomas Bachelet, Assia Djefal-Kerrar, Christophe Hennequin & Nicolas Foray. (2017) Radiobiological Characterization of Tuberous Sclerosis: a Delay in the Nucleo-Shuttling of ATM May Be Responsible for Radiosensitivity. Molecular Neurobiology 55:6, pages 4973-4983.
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Slawomir Kumala, Krzysztof Fujarewicz, Dheekollu Jayaraju, Joanna Rzeszowska-Wolny & Ronald Hancock. (2013) Repair of DNA Strand Breaks in a Minichromosome In Vivo: Kinetics, Modeling, and Effects of Inhibitors. PLoS ONE 8:1, pages e52966.
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A. Joubert, G. Vogin, C. Devic, A. Granzotto, M. Viau, M. Maalouf, C. Thomas, C. Colin & N. Foray. (2011) Biologie des radiations : avancées majeures et perspectives pour la radiothérapie. Cancer/Radiothérapie 15:5, pages 348-354.
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Junji Magae, Chiharu Furukawa & Hiromitsu Ogata. (2011) Dose-Rate Effect on Proliferation Suppression in Human Cell Lines Continuously Exposed to γ Rays. Radiation Research 176:4, pages 447.
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Jérôme Gastaldo, Muriel Viau, Michael Bouchot, Aurélie Joubert, Anne-Marie Charvet & Nicolas Foray. (2008) Induction and repair rate of DNA damage: A unified model for describing effects of external and internal irradiation and contamination with heavy metals. Journal of Theoretical Biology 251:1, pages 68-81.
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A. Joubert & N. Foray. (2007) Radiosensibilité intrinsèque et cassures double–brin de l'ADN dans les cellules humaines. Cancer/Radiothérapie 11:3, pages 129-142.
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Nicolas Foray, Anne-Marie Charvet, David Duchemin, Vincent Favaudon & Daniel Lavalette. (2005) The repair rate of radiation-induced DNA damage: A stochastic interpretation based on the Gamma function. Journal of Theoretical Biology 236:4, pages 448-458.
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Hiroaki Terato & Hiroshi Ide. (2004) Clustered DNA damage induced by heavy ion particles. Biological Sciences in Space 18:4, pages 206-215.
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Ekkehard Dikomey, Kerstin Borgmann, Ingo Brammer & Ulla Kasten-Pisula. (2003) Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts. Toxicology 193:1-2, pages 125-135.
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Francis A. Cucinotta. (1999) Issues in risk assessment from solar particle events. Radiation Measurements 30:3, pages 261-268.
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Ping-Kun Zhou, Anthony R.M Sproston, Brian Marples, Catherine M.L West, Geoffrey P Margison & Jolyon H Hendry. (1998) The radiosensitivity of human fibroblast cell lines correlates with residual levels of DNA double-strand breaks. Radiotherapy and Oncology 47:3, pages 271-276.
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N. Foray, C.F. Arlett & E.P. Malaise. (1997) Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: A closer look. Biochimie 79:9-10, pages 567-575.
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