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Research Article

Tocotrienols inhibit growth of ZR-75–1 breast cancer cells

Pages 95-103 | Published online: 06 Jul 2009

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Wong Weng-Yew, Kanga Rani Selvaduray, Cheng Hwee Ming & Kalanithi Nesaretnam. (2009) Suppression of Tumor Growth by Palm Tocotrienols Via the Attenuation of Angiogenesis. Nutrition and Cancer 61:3, pages 367-373.
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Articles from other publishers (29)

Anh Thu Tran, Malathi Ramalinga, Habib Kedir, Robert Clarke & Deepak Kumar. (2014) Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells. European Journal of Nutrition 54:2, pages 265-272.
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R. R. S. Shaharom, M. N. Nayan, M. M. N. Radzi, R. Akbar & S. A Jusoh. (2013) Molecular docking study of a tocotrienol and P-glycoprotein. Molecular docking study of a tocotrienol and P-glycoprotein.
Barrie Tan, Ronald Watson & Victor PreedyMokenge Malafa & Kazim Husain. 2012. Tocotrienols. Tocotrienols 241 258 .
Barrie Tan, Ronald Watson & Victor PreedyFrancesca Pilolli, Marta Piroddi, Elisa Pierpaoli, Silvia Ciffolilli, Mauro Provinciali & Francesco Galli. 2012. Tocotrienols. Tocotrienols 117 134 .
Weili Xu, Ming Du, Yonghuan Zhao, Qi Wang, Wenguang Sun & Bingqing Chen. (2012) γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells. The Journal of Nutritional Biochemistry 23:7, pages 800-807.
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Dorrelyn Patacsil, Anh Thu Tran, Youn Sook Cho, Simeng Suy, Francisco Saenz, Irina Malyukova, Habtom Ressom, Sean P. Collins, Robert Clarke & Deepak Kumar. (2012) Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells. The Journal of Nutritional Biochemistry 23:1, pages 93-100.
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Kalanithi Nesaretnam, Puvaneswari Meganathan, Sheela Devi Veerasenan & Kanga Rani Selvaduray. (2011) Tocotrienols and breast cancer: the evidence to date. Genes & Nutrition 7:1, pages 3-9.
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Kanga Rani Selvaduray, Ammu K. Radhakrishnan, Methil Kannan Kutty & Kalanithi Nesaretnam. (2011) Palm tocotrienols decrease levels of pro-angiogenic markers in human umbilical vein endothelial cells (HUVEC) and murine mammary cancer cells. Genes & Nutrition 7:1, pages 53-61.
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Valentina Viola, Francesca Pilolli, Marta Piroddi, Elisa Pierpaoli, Fiorenza Orlando, Mauro Provinciali, Michele Betti, Francesco Mazzini & Francesco Galli. (2011) Why tocotrienols work better: insights into the in vitro anti-cancer mechanism of vitamin E. Genes & Nutrition 7:1, pages 29-41.
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Kanga Rani SelvadurayAmmu K. RadhakrishnanMethil Kannan KuttyKalanithi Nesaretnam. (2010) Palm Tocotrienols Inhibit Proliferation of Murine Mammary Cancer Cells and Induce Expression of Interleukin-24 mRNA. Journal of Interferon & Cytokine Research 30:12, pages 909-916.
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Wei Ney Yap, Norazean Zaiden, Yee Ling Tan, Chang Piek Ngoh, Xue Wu Zhang, Y.C. Wong, M.T. Ling & Yee Leng Yap. (2010) Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells. Cancer Letters 291:2, pages 187-199.
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Raffaella Comitato, Guido Leoni, Raffaella Canali, Roberto Ambra, Kalanithi Nesaretnam & Fabio Virgili. (2010) Tocotrienols activity in MCF-7 breast cancer cells: Involvement of ERβ signal transduction. Molecular Nutrition & Food Research 54:5, pages 669-678.
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Elisa Pierpaoli, Valentina Viola, Francesca Pilolli, Marta Piroddi, Francesco Galli & Mauro Provinciali. (2010) γ- and δ-tocotrienols exert a more potent anticancer effect than α-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. Life Sciences 86:17-18, pages 668-675.
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Mun‐Li Yam, Sitti Rahma Abdul Hafid, Hwee‐Ming Cheng & Kalanithi Nesaretnam. (2009) Tocotrienols Suppress Proinflammatory Markers and Cyclooxygenase‐2 Expression in RAW264.7 Macrophages. Lipids 44:9, pages 787-797.
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Raffaella Comitato, Kalanithi Nesaretnam, Guido Leoni, Roberto Ambra, Raffaella Canali, Alessandro Bolli, Maria Marino & Fabio Virgili. (2009) A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERβ signal transduction. American Journal of Physiology-Endocrinology and Metabolism 297:2, pages E427-E437.
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Liva Harinantenaina. 2008. Tocotrienols. Tocotrienols 43 60 .
Bruce Blumberg, Kameran Johnson & Tiffany Hsu. 2008. Tocotrienols. Tocotrienols 331 339 .
Charles Elson & Huanbiao Mo. 2008. Tocotrienols. Tocotrienols 185 207 .
Paul Sylvester. 2008. Tocotrienols. Tocotrienols 119 139 .
Kalanithi Nesaretnam, Teoh Hoon Koon, Kanga Rani Selvaduray, Richard S. Bruno & Emily Ho. (2008) Modulation of cell growth and apoptosis response in human prostate cancer cells supplemented with tocotrienols. European Journal of Lipid Science and Technology 110:1, pages 23-31.
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Chandan K. Sen, Savita Khanna & Sashwati Roy. (2007) Tocotrienols in health and disease: The other half of the natural vitamin E family. Molecular Aspects of Medicine 28:5-6, pages 692-728.
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Mariana Rickmann, Eva C. Vaquero, Juan Ramón Malagelada & Xavier Molero. (2007) Tocotrienols Induce Apoptosis and Autophagy in Rat Pancreatic Stellate Cells Through the Mitochondrial Death Pathway. Gastroenterology 132:7, pages 2518-2532.
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Kalanithi Nesaretnam, Wong Weng Yew & Mohd Basri Wahid. (2007) Tocotrienols and cancer: Beyond antioxidant activity. European Journal of Lipid Science and Technology 109:4, pages 445-452.
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Paul W. Sylvester. 2007. Vitamin E. Vitamin E 329 356 .
Chandan K. Sen, Savita Khanna, Cameron Rink & Sashwati Roy. 2007. Vitamin E. Vitamin E 203 261 .
Chandan K. Sen, Savita Khanna & Sashwati Roy. (2006) Tocotrienols: Vitamin E beyond tocopherols. Life Sciences 78:18, pages 2088-2098.
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KALANITHI NESARETNAM, ROBERTO AMBRA, KANGA RANI SELVADURAY, AMMU RADHAKRISHNAN, RAFFAELLA CANALI & FABIO VIRGILI. (2004) Tocotrienol-Rich Fraction from Palm Oil and Gene Expression in Human Breast Cancer Cells. Annals of the New York Academy of Sciences 1031:1, pages 143-157.
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Kalanithi Nesaretnam, Roberto Ambra, Kanga Rani Selvaduray, Ammu Radhakrishnan, Karin Reimann, Ghazali Razak & Fabio Virgili. (2004) Tocotrienol-rich fraction from palm oil affects gene expression in tumors resulting from MCF-7 cell inoculation in athymic mice. Lipids 39:5, pages 459-467.
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Mohd Sokhini Abdul Mutalib, Huzwah Khaza'ai & Klaus W.J. Wahle. (2003) Palm-tocotrienol rich fraction (TRF) is a more effective inhibitor of LDL oxidation and endothelial cell lipid peroxidation than α-tocopherol in vitro. Food Research International 36:5, pages 405-413.
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