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A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort

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Pages 99-113 | Published online: 13 Aug 2009

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Meisam Barati, Masoumeh Jabbari, Hamid Nickho, Mojgan Esparvarinha, Amirreza Javadi Mamaghani, Hasan Majdi, Anwar Fathollahi & Sayed Hossein Davoodi. (2021) Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review. Nutrition and Cancer 73:6, pages 956-967.
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Christina E. Larder, Michèle M. Iskandar & Stan Kubow. (2023) Collagen Hydrolysates: A Source of Bioactive Peptides Derived from Food Sources for the Treatment of Osteoarthritis. Medicines 10:9, pages 50.
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Daniel Martínez-Puig, Ester Costa-Larrión, Nuria Rubio-Rodríguez & Patricia Gálvez-Martín. (2023) Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge. Nutrients 15:6, pages 1332.
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Mahesh Shenoy, Nishath Sayed Abdul, Zeeshan Qamar, Bader Musfer Al Bahri, Khalid Zuhair K Al Ghalayini & Ateet Kakti. (2022) Collagen Structure, Synthesis, and Its Applications: A Systematic Review. Cureus.
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Ji-Eun Kim, Eun-Young Kwon & Youngji Han. (2022) A Collagen Hydrolysate Containing Tripeptides Ameliorates Sarcopenia in Middle-Aged Mice. Molecules 27:9, pages 2718.
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Ting-Yu Chang, Kuo-Cheng Lan, Kuo-Tai Hua & Shing-Hwa Liu. (2022) In vitro genotoxicity assessment and 28-day repeated dose oral toxicity study of steady-calcium formula in rats. Toxicology Reports 9, pages 834-841.
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Paul T. von Hippel. (2021) Do collagen supplements reduce symptoms of osteoarthritis? Meta-analytic results do not support strong conclusions. International Orthopaedics 45:12, pages 3283-3284.
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Jun-Hui Cheng, Xiao-Yu Zhang, Zhen Wang, Xia Zhang, Shi-Cheng Liu, Xiao-Yan Song, Yu-Zhong Zhang, Jun-Mei Ding, Xiu-Lan Chen & Fei Xu. (2021) Potential of Thermolysin-like Protease A69 in Preparation of Bovine Collagen Peptides with Moisture-Retention Ability and Antioxidative Activity. Marine Drugs 19:12, pages 676.
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Ali Mobasheri, Armaghan Mahmoudian, Ursule Kalvaityte, Ilona Uzieliene, Christina E. Larder, Michèle M. Iskandar, Stan Kubow, Paulo Cesar Hamdan, Cyro Scala de AlmeidaJrJr, Lacey J. Favazzo, Luc J.C. van Loon, Pieter J. Emans, Pérola G. Plapler & Michael J. Zuscik. (2021) A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?. Current Rheumatology Reports 23:11.
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Christina E. Larder, Michèle M. Iskandar & Stan Kubow. (2021) Gastrointestinal Digestion Model Assessment of Peptide Diversity and Microbial Fermentation Products of Collagen Hydrolysates. Nutrients 13:8, pages 2720.
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Anaam Mohammed & Siran He. (2021) A Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy of a Hydrolyzed Chicken Collagen Type II Supplement in Alleviating Joint Discomfort. Nutrients 13:7, pages 2454.
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Denise Zdzieblik, Judith Brame, Steffen Oesser, Albert Gollhofer & Daniel König. (2021) The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial. Nutrients 13:2, pages 523.
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Chisa Tometsuka, Noriko Funato, Kazunori Mizuno & Yuki Taga. (2021) Long-term intake of ginger protease-degraded collagen hydrolysate reduces blood lipid levels and adipocyte size in mice. Current Research in Food Science 4, pages 175-181.
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Germain Honvo, Laetitia Lengelé, Alexia Charles, Jean-Yves Reginster & Olivier Bruyère. (2020) Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review With Evidence Mapping. Rheumatology and Therapy 7:4, pages 703-740.
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Harshita Arora, Nan Shang, Khushwant S. Bhullar & Jianping Wu. (2020) Pea protein-derived tripeptide LRW shows osteoblastic activity on MC3T3-E1 cells via the activation of the Akt/Runx2 pathway . Food & Function 11:8, pages 7197-7207.
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