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Original Paper

Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl/HCO3 exchanger, AE1

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Pages 423-433 | Received 23 Aug 2004, Published online: 09 Jul 2009

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Read on this site (5)

Emanuela Berrino & Claudiu T. Supuran. (2019) Novel approaches for designing drugs that interfere with pH regulation. Expert Opinion on Drug Discovery 14:3, pages 231-248.
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Min Jeong Ji & Jeong Hee Hong. (2019) An overview of carbonic anhydrases and membrane channels of synoviocytes in inflamed joints. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1615-1622.
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Emir Alper Türkoğlu, Murat Şentürk, Claudiu T. Supuran & Deniz Ekinci. (2017) Carbonic anhydrase inhibitory properties of some uracil derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 74-77.
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Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
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Erik R Swenson. (2014) Safety of carbonic anhydrase inhibitors. Expert Opinion on Drug Safety 13:4, pages 459-472.
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Articles from other publishers (21)

Alessio Nocentini & Stefano Fais. 2021. pH-Interfering Agents as Chemosensitizers in Cancer Therapy. pH-Interfering Agents as Chemosensitizers in Cancer Therapy 47 62 .
Erik R. Swenson, Akshay Kumar, Nimisha Kumar & Bernardo V. Alvarez. 2021. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets 37 77 .
Guanyu Hao, Zhi Ping Xu & Li Li. (2018) Manipulating extracellular tumour pH: an effective target for cancer therapy. RSC Advances 8:39, pages 22182-22192.
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Emanuela Berrino, Silvia Bua, Mattia Mori, Maurizio Botta, Vallabhaneni S. Murthy, Vijayaparthasarathi Vijayakumar, Yasinalli Tamboli, Gianluca Bartolucci, Alessandro Mugelli, Elisabetta Cerbai, Claudiu T. Supuran & Fabrizio Carta. (2017) Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors. Molecules 22:7, pages 1049.
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Sara Granja, Diana Tavares-Valente, Odília Queirós & Fátima Baltazar. (2017) Value of pH regulators in the diagnosis, prognosis and treatment of cancer. Seminars in Cancer Biology 43, pages 17-34.
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Tayfun Arslan, Emir Alper Türkoğlu, Murat Şentürk & Claudiu T. Supuran. (2016) Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides. Bioorganic & Medicinal Chemistry Letters 26:24, pages 5867-5870.
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Kamini Marathe, Nevin McVicar, Alex Li, Miranda Bellyou, Susan Meakin & Robert Bartha. (2016) Topiramate induces acute intracellular acidification in glioblastoma. Journal of Neuro-Oncology 130:3, pages 465-472.
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Erik R. Swenson. (2014) New Insights into Carbonic Anhydrase Inhibition, Vasodilation, and Treatment of Hypertensive-Related Diseases. Current Hypertension Reports 16:9.
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Etienne Frumence, Sandrine GenetetPierre RipocheAchille Iolascon, Immacolata Andolfo, Caroline Le Van KimYves ColinIsabelle Mouro-ChanteloupClaude Lopez. (2013) Rapid Cl − /HCO 3 − exchange kinetics of AE1 in HEK293 cells and hereditary stomatocytosis red blood cells . American Journal of Physiology-Cell Physiology 305:6, pages C654-C662.
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Andrew K. Stewart & Seth L. Alper. 2013. Seldin and Giebisch's The Kidney. Seldin and Giebisch's The Kidney 1861 1915 .
Giuseppina De Simone & Claudiu T. Supuran. (2012) (In)organic anions as carbonic anhydrase inhibitors. Journal of Inorganic Biochemistry 111, pages 117-129.
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Teresa A. Sherman, Sharath C. Rongali, Tori A. Matthews, Jason Pfeiffer & Keith Nehrke. (2012) Identification of a nuclear carbonic anhydrase in Caenorhabditis elegans. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:4, pages 808-817.
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Dario Neri & Claudiu T. Supuran. (2011) Interfering with pH regulation in tumours as a therapeutic strategy. Nature Reviews Drug Discovery 10:10, pages 767-777.
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Joseph R. CaseyWilliam S. Sly, Gul N. Shah & Bernardo V. Alvarez. (2009) Bicarbonate homeostasis in excitable tissues: role of AE3 Cl − /HCO 3 − exchanger and carbonic anhydrase XIV interaction . American Journal of Physiology-Cell Physiology 297:5, pages 1091-1102.
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Alessio Innocenti, Andrea Scozzafava & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. Bioorganic & Medicinal Chemistry Letters 19:7, pages 1855-1857.
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Alessio Innocenti, Mika Hilvo, Seppo Parkkila, Andrea Scozzafava & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors: The membrane-associated isoform XV is highly inhibited by inorganic anions. Bioorganic & Medicinal Chemistry Letters 19:4, pages 1155-1158.
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Andrew K. Stewart, Christine E. Kurschat & Seth L. Alper. 2008. Seldin and Giebisch's The Kidney. Seldin and Giebisch's The Kidney 1499 1537 .
Patricio E. Morgan, Silvia Pastoreková, Alan K. Stuart-Tilley, Seth L. Alper & Joseph R. Casey. (2007) Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters. American Journal of Physiology-Cell Physiology 293:2, pages C738-C748.
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Rema Iyer, Albert A. Barrese III, Shilpa Parakh, Christian N. Parker & Brian C. Tripp. (2006) Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. SLAS Discovery 11:7, pages 782-791.
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Haley J. Shandro & Joseph R. Casey. 2006. Chloride Movements Across Cellular Membranes. Chloride Movements Across Cellular Membranes 279 328 .
Adel KardoshNathaniel SorianoYen-Ting LiuJasim UddinNicos A. PetasisFlorence M. HofmanThomas C. ChenAxel H. Schönthal. (2005) Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non–COX-2 inhibitory analog of celecoxib. Blood 106:13, pages 4330-4338.
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