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Biocatalysis and Biotransformation Volume 38, 2020 - Issue 2
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Review Article

Enzyme promiscuity – A light on the “darker” side of enzyme specificity

Prabhjot SinglaDepartment of Biochemistry, Punjab Agricultural University, Ludhiana, India
&
Rachana D. BhardwajDepartment of Biochemistry, Punjab Agricultural University, Ludhiana, IndiaCorrespondence[email protected]
Pages 81-92 | Received 31 Jul 2019, Accepted 18 Nov 2019, Published online: 28 Nov 2019

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Dina A. Maany, Marwa I. Wahba, Mohamed Abo-Alkasem, Mostafa A. El-Abd & Abdelnasser S. S. Ibrahim. (2023) Hexavalent chromium detoxification by haloalkaliphilic Nesterenkonia sp strain NRC-Y immobilized in different matrices. Biocatalysis and Biotransformation 0:0, pages 1-15.
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Jiapeng Li, Yue Yu, Yaning Xu, Fengxi Li, Yuqi Liu, Yifei Sun, Chunyu Wang, Peng Chen & Lei Wang. (2022) Efficient synthesis of 3-hydroxy chromones via oxidative cyclization mediated by lipase. Green Chemistry Letters and Reviews 15:3, pages 689-694.
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Articles from other publishers (15)

Ke Zhang, Tingze Pan, Yangyang Sun, Zhuzhu Tang, Yuhong Ren, Hualei Wang & Dongzhi Wei. (2023) Rational identification of a catalytically promiscuous nitrilase by predicting a unique catalytic triad motif feature through an in silico strategy . Catalysis Science & Technology 13:17, pages 4932-4940.
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Pedro Sousa Sampaio & Pedro Fernandes. (2023) Machine Learning: A Suitable Method for Biocatalysis. Catalysts 13:6, pages 961.
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Rafael B. Dextro, Marli F. Fiore & Paul F. Long. (2023) Resolving Confusion Surrounding d ‐Ala‐ d ‐Ala Ligase Catalysis in Cyanobacterial Mycosporine‐Like Amino Acid (MAA) Biosynthesis . ChemBioChem 24:10.
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Sudipta Mitra, Arnab Sil, Ranjit Biswas & Suman Chakrabarty. (2023) Molecular Thermodynamic Origin of Substrate Promiscuity in the Enzyme Laccase: Toward a Broad-Spectrum Degrader of Dye Effluents. The Journal of Physical Chemistry Letters 14:7, pages 1892-1898.
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Ilya Lyagin, Nikolay Stepanov, Olga Maslova, Olga Senko, Aysel Aslanli & Elena Efremenko. (2022) Not a Mistake but a Feature: Promiscuous Activity of Enzymes Meeting Mycotoxins. Catalysts 12:10, pages 1095.
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Shayan Simay, Mostafa Akbarzadeh-Khiavi, Mohammad M. Pourseif, Jaleh Barar, Azam Safary & Yadollah Omidi. (2022) Recombinant production and characterization of L-glutaminase (glsA) as a promiscuity therapeutic enzyme. Applied Microbiology and Biotechnology 106:17, pages 5511-5524.
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Chao‐Jiu Long, Huan Cao, Ben‐Kun Zhao, Yu‐Fang Tan, Yan‐Hong He, Chu‐Sheng Huang & Zhi Guan. (2022) Merging the Non‐Natural Catalytic Activity of Lipase and Electrosynthesis: Asymmetric Oxidative Cross‐Coupling of Secondary Amines with Ketones. Angewandte Chemie International Edition 61:30.
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Chao‐Jiu Long, Huan Cao, Ben‐Kun Zhao, Yu‐Fang Tan, Yan‐Hong He, Chu‐Sheng Huang & Zhi Guan. (2022) Merging the Non‐Natural Catalytic Activity of Lipase and Electrosynthesis: Asymmetric Oxidative Cross‐Coupling of Secondary Amines with Ketones. Angewandte Chemie 134:30.
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Dennis Larsen, Michel Ferreira, Sébastien Tilloy, Eric Monflier & Sophie R. Beeren. (2022) Unnatural cyclodextrins can be accessed from enzyme-mediated dynamic combinatorial libraries. Chemical Communications 58:14, pages 2287-2290.
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Liuzhu Wang, Shuiqin Jiang, Yangyang Sun, Zeyu Yang, Zhi Chen, Hualei Wang & Dongzhi Wei. (2021) Switching the secondary and natural activity of Nitrilase from Acidovorax facilis 72 W for the efficient production of 2-picolinamide. Biotechnology Letters 43:8, pages 1617-1624.
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Nana Ma, Wenhan Fang, Chuanfei Liu, Xiangquan Qin, Xiling Wang, Longyi Jin, Binju Wang & Zhiqi Cong. (2021) Switching an Artificial P450 Peroxygenase into Peroxidase via Mechanism-Guided Protein Engineering. ACS Catalysis 11:14, pages 8449-8455.
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Maksim Nikulin & Vytas Švedas. (2021) Prospects of Using Biocatalysis for the Synthesis and Modification of Polymers. Molecules 26:9, pages 2750.
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Erika V. M. Orozco & André L. M. Porto. 2021. Biocatalysis for Practitioners. Biocatalysis for Practitioners 113 142 .
Letícia Mara Rasbold, Paulo Ricardo Heinen, José Luis Conceição Silva, Rita Cássia Garcia Simão, Marina Kimiko Kadowaki & Alexandre Maller. (2021) Cunninghamella echinulata PA3S12MM invertase: Biochemical characterization of a promiscuous enzyme . Journal of Food Biochemistry 45:4.
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Zhaoxing Liu, Jiahuang Li, Chen Jie, Bin Wu & Ning Hao. (2021) A multifunctional α-amylase BSGH13 from Bacillus subtilis BS-5 possessing endoglucanase and xylanase activities. International Journal of Biological Macromolecules 171, pages 166-176.
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