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Hematology Volume 8, 2003 - Issue 1
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Research Article

Impaired Phagocyte Antibacterial Effector Functions in β-thalassemia: A Likely Factor in the Increased Susceptibility to Bacterial Infections

Edith Wiener
Pages 35-40 | Published online: 04 Sep 2013

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Li Zhang, Li-Juan Bao, Zheng-Dong Hong, Mu-Xia Yan, Zhi-Hua Zhang, Yan-Mei Li, Qian Ye & Yi-Qian Wang. (2022) Dysregulated Serum Cytokine Production in Pediatric Patients with β-Thalassemia Major. Hemoglobin 46:4, pages 191-196.
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Articles from other publishers (23)

William J. Chen, George P. Kung & Jaya P. Gnana-Prakasam. (2022) Role of Iron in Aging Related Diseases. Antioxidants 11:5, pages 865.
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Shreya Das, Mohd Saqib, Ryan C. MengSridar V. Chittur, Ziqiang Guan, Fengyi Wan & Wei Sun. (2021) Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producing Yersinia pseudotuberculosis . Proceedings of the National Academy of Sciences 119:2.
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Annette d'Arqom, Melvanda G Putri, Yovani Savitri & Andi Muh Rahul Alfaidin. (2020) Vitamin and mineral supplementation for β-thalassemia during COVID-19 pandemic. Future Science OA, pages FSO628.
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Mario Fernández-Ruiz, Patricia Parra, Tamara Ruiz-Merlo, Francisco López-Medrano, Rafael San Juan, Natalia Polanco, Esther González, Amado Andrés & José María Aguado. (2018) Association between baseline serum hepcidin levels and infection in kidney transplant recipients: Potential role for iron overload. Transplant Infectious Disease 20:1, pages e12807.
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Rui Martins & Sylvia Knapp. (2018) Heme and hemolysis in innate immunity: adding insult to injury. Current Opinion in Immunology 50, pages 14-20.
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Ali Bazi, Iraj Shahramian, Hajar Yaghoobi, Majid Naderi & Hakim Azizi. (2017) The Role of Immune System in Thalassemia Major: A Narrative Review. Journal of Pediatrics Review 6:2.
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Teny Tjitra Sari, Arwin Ali P. Akib, Djajadiman Gatot, Alida Roswita Harahap, Saptawati Bardosono & Sri Rezeki S. Hadinegoro. (2017) Pneumococcal vaccination for splenectomized patients with thalassemia major in Indonesia. Vaccine 35:35, pages 4583-4586.
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Matthew S. Karafin, Erica Carpenter, Amy Pan, Pippa Simpson & Joshua J. Field. (2017) Older red cell units are associated with an increased incidence of infection in chronically transfused adults with sickle cell disease. Transfusion and Apheresis Science 56:3, pages 345-351.
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Rui Martins, Julia Maier, Anna-Dorothea Gorki, Kilian V M Huber, Omar Sharif, Philipp Starkl, Simona Saluzzo, Federica Quattrone, Riem Gawish, Karin Lakovits, Michael C Aichinger, Branka Radic-Sarikas, Charles-Hugues Lardeau, Anastasiya Hladik, Ana Korosec, Markus Brown, Kari Vaahtomeri, Michelle Duggan, Dontscho Kerjaschki, Harald Esterbauer, Jacques Colinge, Stephanie C Eisenbarth, Thomas Decker, Keiryn L Bennett, Stefan Kubicek, Michael Sixt, Giulio Superti-Furga & Sylvia Knapp. (2016) Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature Immunology 17:12, pages 1361-1372.
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Jun-Kai Kao, Shih-Chung Wang, Li-Wei Ho, Shi-Wei Huang, Shu-Hao Chang, Rei-Cheng Yang, Yu-Yuan Ke, Chun-Ying Wu, Jiu-Yao Wang & Jeng-Jer Shieh. (2016) Chronic Iron Overload Results in Impaired Bacterial Killing of THP-1 Derived Macrophage through the Inhibition of Lysosomal Acidification. PLOS ONE 11:5, pages e0156713.
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Siew M. Fong, Ke J. Wong, Masako Fukushima & Tsin W. Yeo. (2015) Thalassemia Major Is a Major Risk Factor for Pediatric Melioidosis in Kota Kinabalu, Sabah, Malaysia. Clinical Infectious Diseases 60:12, pages 1802-1807.
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Abdolreza Sotoodeh Jahromi & Karamatollah Rahmanian. (2015) Immunity to tetanus in major beta thalassemia patients. Clinical and Experimental Vaccine Research 4:2, pages 184.
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Shyh-Shin Chiou, Chao-Jung Tsao, Shih-Meng Tsai, Ye-Ru Wu, Yu-Mei Liao, Pei-Chin Lin & Li-Yu Tsai. (2014) Metabolic Pathways Related to Oxidative Stress in Patients With Hemoglobin H Disease and Iron Overload. Journal of Clinical Laboratory Analysis 28:4, pages 261-268.
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Karolina Benesova, Maja Vujić Spasić, Sebastian M. Schaefer, Jens Stolte, Tomi Baehr-Ivacevic, Katharina Waldow, Zhe Zhou, Ursula Klingmueller, Vladimir Benes, Marcus A. Mall & Martina U. Muckenthaler. (2012) Hfe Deficiency Impairs Pulmonary Neutrophil Recruitment in Response to Inflammation. PLoS ONE 7:6, pages e39363.
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Wansa Banyatsuppasin, Punnee Butthep, Vichai Atichartakarn, Ammarin Thakkinstian, Napaporn Archararit, Kovit Pattanapanyasat & Suporn Chuncharunee. (2010) Activation of mononuclear phagocytes and its relationship to asplenia and phosphatidylserine exposing red blood cells in hemoglobin E/β‐thalassemia patients. American Journal of Hematology 86:1, pages 89-92.
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Eitan Fibach, Ee‐Shien Tan, Saumya Jamuar, Ivy Ng, Johnny Amer & Eliezer A. Rachmilewitz. (2010) Amelioration of oxidative stress in red blood cells from patients with β‐thalassemia major and intermedia and E‐β‐thalassemia following administration of a fermented papaya preparation. Phytotherapy Research 24:9, pages 1334-1338.
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Caroline P. Ozment & Jennifer L. Turi. (2009) Iron overload following red blood cell transfusion and its impact on disease severity. Biochimica et Biophysica Acta (BBA) - General Subjects 1790:7, pages 694-701.
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Eitan Fibach, Ada Goldfarb & Johnny Amer. 2008. Dietary Modulation of Cell Signaling Pathways. Dietary Modulation of Cell Signaling Pathways.
Johnny Amer, Ada Goldfarb, Eliezer A. Rachmilewitz & Eitan Fibach. (2008) Fermented papaya preparation as redox regulator in blood cells of β ‐thalassemic mice and patients . Phytotherapy Research 22:6, pages 820-828.
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Moni Magrisso & Robert S. Marks. 2008. Handbook of Biosensors and Biochips. Handbook of Biosensors and Biochips.
Galia Rahav, Vania Volach, Mervyn Shapiro, Deborah Rund, Eliezer A. Rachmilewitz & Ada Goldfarb. (2006) Severe infections in thalassaemic patients: prevalence and predisposing factors. British Journal of Haematology 133:6, pages 667-674.
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Johnny Amer & Eitan Fibach. (2005) Chronic oxidative stress reduces the respiratory burst response of neutrophils from beta-thalassaemia patients. British Journal of Haematology 129:3, pages 435-441.
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Allen C. Cheng & Bart J. Currie. (2005) Melioidosis: Epidemiology, Pathophysiology, and Management. Clinical Microbiology Reviews 18:2, pages 383-416.
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