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Hematology Volume 8, 2003 - Issue 6
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Articles

Clopidogrel: Interactions with the P2Y12 Receptor and Clinical Relevance

Robert T. DorsamThe Sol Sherry Thrombosis Research Center Temple University School of MedicinePhiladelphiaPAUSA
,
Swaminathan MurugappanDepartment of Physiology Temple University School of MedicinePhiladelphiaPAUSA
,
Zhongren DingDepartment of Physiology Temple University School of MedicinePhiladelphiaPAUSA
&
Satya P. KunapuliDepartment of Physiology Temple University School of MedicinePhiladelphiaPAUSA
Pages 359-365 | Published online: 04 Sep 2013

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Anas Najjar & Rafik Karaman. (2019) Successes, failures, and future prospects of prodrugs and their clinical impact. Expert Opinion on Drug Discovery 14:3, pages 199-220.
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Italo Porto, Simona Giubilato, Giovanni Luigi De Maria, Luigi Marzio Biasucci & Filippo Crea. (2009) Platelet P2Y12 receptor inhibition by thienopyridines: status and future. Expert Opinion on Investigational Drugs 18:9, pages 1317-1332.
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Articles from other publishers (12)

Roger Gregory Biringer. (2023) Migraine signaling pathways: purine metabolites that regulate migraine and predispose migraineurs to headache. Molecular and Cellular Biochemistry 478:12, pages 2813-2848.
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Ri Han, Hongryul Yoon, Jiho Yoo & Yoonji Lee. (2023) Systematic analyses of the sequence conservation and ligand interaction patterns of purinergic P1 and P2Y receptors provide a structural basis for receptor selectivity. Computational and Structural Biotechnology Journal 21, pages 889-898.
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Dong Pan, Xiaoming Rong, Honghong Li, Zhenhong Deng, Jia Wang, Xiaohuan Liu, Lei He, Yongteng Xu & Yamei Tang. (2022) Anti-platelet Therapy Is Associated With Lower Risk of Dementia in Patients With Cerebral Small Vessel Disease. Frontiers in Aging Neuroscience 14.
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Daisuke Kitano, Suguru Migita, Yuxin Li, Rie Takahashi, Yoshiki Taniguchi, Takafumi Kurosawa, Mitsumasa Sudo, Hironori Haruta, Takafumi Hiro, Tadateru Takayama, Masako Mitsumata, Taro Matsumoto, Yasuo Okumura & Atsushi Hirayama. (2022) Effect of Rivaroxaban and Clopidogrel Combination Therapy on In-Stent Responses After Everolimus-Eluting Stent Implantation in a Porcine Coronary Model. Journal of Atherosclerosis and Thrombosis 29:1, pages 69-81.
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Nichole Orr-Burks, Jackelyn Murray, Kyle V. Todd, Abhijeet Bakre & Ralph A. Tripp. (2021) Drug repositioning of Clopidogrel or Triamterene to inhibit influenza virus replication in vitro. PLOS ONE 16:10, pages e0259129.
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Nichole Orr-Burks, Jackelyn Murray, Kyle V. Todd, Abhijeet Bakre & Ralph A. Tripp. (2021) G-Protein-Coupled Receptor and Ion Channel Genes Used by Influenza Virus for Replication. Journal of Virology 95:9.
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Aimee M Deaton, Fan Fan, Wei Zhang, Phuong A Nguyen, Lucas D Ward & Paul Nioi. (2019) Rationalizing Secondary Pharmacology Screening Using Human Genetic and Pharmacological Evidence. Toxicological Sciences 167:2, pages 593-603.
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Chaoyan Qin, Jinfeng Zhou, Yuan Gao, Weiming Lai, Cuixia Yang, Yingying Cai, Shuai Chen & Changsheng Du. (2017) Critical Role of P2Y12 Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis. The Journal of Immunology 199:1, pages 72-81.
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Haripriya ShankarBryan N. KahnerJanani PrabhakarParth LakhaniSoochong KimSatya P. Kunapuli. (2006) G-protein–gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases. Blood 108:9, pages 3027-3034.
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Christian Gachet. (2006) REGULATION OF PLATELET FUNCTIONS BY P2 RECEPTORS. Annual Review of Pharmacology and Toxicology 46:1, pages 277-300.
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Christian Gachet. (2005) The platelet P2 receptors as molecular targets for old and new antiplatelet drugs. Pharmacology & Therapeutics 108:2, pages 180-192.
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A. Jakubowski, S. Chlopicki, R. Olszanecki, J. Jawien, M. Lomnicka, J.P. Dupin & R.J. Gryglewski. (2005) Endothelial action of thienopyridines and thienopyrimidinones in the isolated guinea pig heart. Prostaglandins, Leukotrienes and Essential Fatty Acids 72:2, pages 139-145.
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