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Haemostasis and Thrombosis

Experience with recombinant-activated factor VII in 30 patients with congenital factor VII deficiency

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Pages 55-62 | Published online: 04 Sep 2013

Keep up to date with the latest research on this topic with citation updates for this article.

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Alessandro Casini & Philippe de Moerloose. (2016) Factor concentrates for rare congenital coagulation disorders: where are we now?. Expert Opinion on Orphan Drugs 4:1, pages 49-62.
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Antonio Girolami, Giulia Berti de Marinis, Emanuela Bonamigo & Anna Maria Lombardi. (2012) Recombinant FVIIa concentrate-associated thrombotic events in congenital bleeding disorders other than hemophilias. Hematology 17:6, pages 346-349.
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Sujit Sheth, Gerald Soff, Beau Mitchell, David Green, Shipra Kaicker, Fernando Fireman, Oya Tugal, Ludovico Guarini, Patricia Giardina & Louis Aledort. (2012) Managing incidentally diagnosed isolated factor VII deficiency perioperatively: a brief expert consensus report. Expert Review of Hematology 5:1, pages 47-50.
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Articles from other publishers (22)

Rezan Abdul-Kadir & Keith Gomez. (2022) Reproductive health and hemostatic issues in women and girls with congenital factor VII deficiency: A systematic review. Journal of Thrombosis and Haemostasis 20:12, pages 2758-2772.
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Derek S. Sim, Cornell R. Mallari, John M. Teare, Richard I. Feldman, Maxine Bauzon & Terry W. Hermiston. (2021) In vitro characterization of CT‐001—a short‐acting factor VIIa with enhanced prohemostatic activity. Research and Practice in Thrombosis and Haemostasis 5:5, pages e12530.
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Anand Suresh Somkuwar, Saira Merchant, Rajkumar Meshram, Mukesh Waghmare, Manisha Mahalinge & Tushar Somkuwar. (2019) ISOLATED CONGENITAL FACTOR VII DEFICIENCY. Indian Journal of Child Health 06:11, pages 629-631.
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Е. М. Шифман, А. В. Куликов, Александр Михайлович Роненсон, И. С. Абазова, Л. В. Адамян, М. Д. Андреева, Н. В. Артымук, О. Р. Баев, С. В. Баринов, Т. Е. Белокриницкая, С. И. Блауман, И. В. Братищев, А. А. Бухтин, В. Я. Вартанов, А. Б. Волков, В. С. Гороховский, Н. В. Долгушина, А. Н. Дробинская, С. В. Кинжалова, И. З. Китиашвили, И. Ю. Коган, А. Ю. Королев, В. И. Краснопольский, И. И. Кукарская, М. А. Курцер, Д. В. Маршалов, А. А. Матковский, А. М. Овезов, Г. А. Пенжоян, Т. Ю. Пестрикова, В. А. Петрухин, А. М. Приходько, Н. В. Протопопова, Д. Н. Проценко, А. В. Пырегов, Ю. С. Распопин, О. В. Рогачевский, О. В. Рязанова, Г. М. Савельева, Ю. А. Семенов, С. И. Ситкин, И. Ф. Фаткуллин, Т. А. Федорова, О. С. Филиппов, М. В. Швечкова, Р. Г. Шмаков, А. В. Щеголев & И. Б. Заболотских. (2019) Профилактика, алгоритм ведения, анестезия и интенсивная терапия при послеродовых кровотечениях. Клинические рекомендации. Annals of Critical Care:3, pages 9-33.
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N. V. Artymuk, A. A. Astahov, T. E. Belokrinitskaya, A. Yu. Bulanov, I. B. Zabolotskikh, A. V. Kulikov, A. A. Matkovskiy, A. M. Ovezov, D. N. Protsenko, A. M. Ronenson, O. V. Riazanova, S. V. Sin'kov, O. S. Filippov & E. M. Shifman. (2019) Intensive care for disseminated intravascular coagulation syndrome (dic-syndrome, coagulopathy) in obstetrics. Anesteziologiya i Reanimatologiya:2, pages 5.
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Sibylle A. Kozek-Langenecker, Aamer B. Ahmed, Arash Afshari, Pierre Albaladejo, Cesar Aldecoa, Guidrius Barauskas, Edoardo De Robertis, David Faraoni, Daniela C. Filipescu, Dietmar Fries, Thorsten Haas, Matthias Jacob, Marcus D. Lancé, Juan V.L. Pitarch, Susan Mallett, Jens Meier, Zsolt L. Molnar, Niels Rahe-Meyer, Charles M. Samama, Jakob Stensballe, Philippe J.F. Van der Linden, Anne J. Wikkelsø, Patrick Wouters, Piet Wyffels & Kai Zacharowski. (2017) Management of severe perioperative bleeding. European Journal of Anaesthesiology 34:6, pages 332-395.
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M. Faranoush, Hassan Abolghasemi, Gh. Toogeh, M. Karimi, P. Eshghi, M. Managhchi, H. Hoorfar, B. Keikhaei Dehdezi, A. Mehrvar, B. Khoeiny, K. Kamyar, R. Heshmat, M. R. Baghaeipour, N. B. Mirbehbahani, R. Fayazfar, M. Ahmadinejad & M. Naderi. (2014) A Comparison Between Recombinant Activated Factor VII (Aryoseven) and Novoseven in Patients With Congenital Factor VII Deficiency. Clinical and Applied Thrombosis/Hemostasis 21:8, pages 724-728.
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Ulla Hedner. (2015) Recombinant activated factor VII: 30 years of research and innovation. Blood Reviews 29, pages S4-S8.
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H. Shirasawa, T. Yoshioka, K. Sawada & Y. Terada. (2013) Repeated recombinant activated factor VII administration in a patient with congenital factor VII deficiency undergoing modified radical hysterectomy: a case report . Haemophilia 20:1.
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F. Peyvandi, I. Garagiola & S. Seregni. (2013) Future of coagulation factor replacement therapy. Journal of Thrombosis and Haemostasis 11, pages 84-98.
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Sibylle A. Kozek-Langenecker, Arash Afshari, Pierre Albaladejo, Cesar Aldecoa Alvarez Santullano, Edoardo De Robertis, Daniela C. Filipescu, Dietmar Fries, Klaus Görlinger, Thorsten Haas, Georgina Imberger, Matthias Jacob, Marcus Lancé, Juan Llau, Sue Mallett, Jens Meier, Niels Rahe-Meyer, Charles Marc Samama, Andrew Smith, Cristina Solomon, Philippe Van der Linden, Anne Juul Wikkelsø, Patrick Wouters & Piet Wyffels. (2013) Management of severe perioperative bleeding. European Journal of Anaesthesiology 30:6, pages 270-382.
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Zafer Salcioglu, Arzu Akcay, Hulya Sayilan Sen, Gonul Aydogan, Ferhan Akici, Deniz Tugcu, Nuray Aktay Ayaz & Zafer Baslar. (2012) Factor VII Deficiency. Clinical and Applied Thrombosis/Hemostasis 18:6, pages 588-593.
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Antonio Girolami, Nicole Candeo, Silvia Vettore, Anna Maria Lombardi & Bruno Girolami. (2009) The clinical significance of the lack of arterial or venous thrombosis in patients with congenital prothrombin or FX deficiency. Journal of Thrombosis and Thrombolysis 29:3, pages 299-302.
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Won Seok LeeYoung Sil Park. (2010) A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency. Korean Journal of Pediatrics 53:10, pages 913.
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N. Liu, S. Aldea, D. François, M. Cherqui-Michel, M. Giansily-Blaizot & M. Fischler. (2009) Recombinant activated factor VII for a patient with factor VII deficiency undergoing urgent intracerebral haematoma evacuation with underlying cavernous angioma. British Journal of Anaesthesia 103:6, pages 858-860.
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Paris MargaritisElise RoyMajed N. AljamaliHarre D. DowneyUrs GigerShangzhen ZhouElizabeth MerricksAaron DillowMirella Ezban, Timothy C. NicholsKatherine A. High. (2009) Successful treatment of canine hemophilia by continuous expression of canine FVIIa. Blood 113:16, pages 3682-3689.
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Shannon L. Meeks. 2009. Transfusion Medicine and Hemostasis. Transfusion Medicine and Hemostasis 549 550 .
M. LAPECORELLA & G. MARIANI. (2008) Factor VII deficiency: defining the clinical picture and optimizing therapeutic options. Haemophilia 14:6, pages 1170-1175.
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Ali Abbas Yilmaz, Saban Yalcin, Hacer Serdaroglu, Murat Sonmezer & Asuman Uysalel. (2008) Prophylaxis with recombinant-activated factor VII (rFVIIa) for minimally invasive surgery in a patient with congenital factor VII deficiency: a case report with a single-low dose of rFVIIa. Blood Coagulation & Fibrinolysis 19:7, pages 693-695.
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B. LAURITZEN, U. HEDNER, P.B. JOHANSEN, M. TRANHOLM & M. EZBAN. (2008) Recombinant human factor VIIa and a factor VIIa‐analogue reduces heparin and low molecular weight heparin (LMWH)‐induced bleeding in rats. Journal of Thrombosis and Haemostasis 6:5, pages 804-811.
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Michael Felfernig & Michael Huepfl. (2008) Experience of recombinant activated factor VII (NovoSeven®) in the operating theatre and intensive care unit for the management of intracranial bleeding in nonhaemophilic patients. Clinical Neurology and Neurosurgery 110:3, pages 227-232.
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A. Girolami, R. Scandellari, M. Scapin & S. Vettore. 2008. Vitamin K. Vitamin K 281 374 .

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