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Hematology Volume 4, 1999 - Issue 1
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Erythropoiesis

Comparison of Cytotoxic Aldehyde Generation in Beta-Thalassemia Patients Chelated with Deferoxamine or Deferiprone (L1) Versus NO Chelation

Wally J. BartfayHeart and Stroke/Lewar Centre of Excellence for Cardiovascular Research, University of Toronto, The Toronto Hospital, Toronto, Ontario, Canada
,
Denis C. LehotayThe University of Toronto, Department of Laboratory Medicine and Pathology, Toronto, Ontario, Canada
,
Graham D. SherCanadian Blood Services, Medical Scientific and Clinical Management, Ottawa, Ontario, Canada
,
Emma BartfayDepartment of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada
,
Bev TylerHeart and Stroke/Lewar Centre of Excellence for Cardiovascular Research, University of Toronto, The Toronto Hospital, Toronto, Ontario, Canada
,
Xiaoping LuoThe Hospital For Sick Children, Division of Clinical Biochemistry, Toronto, Ontario, Canada
&
Peter P. LiuHeart and Stroke/Lewar Centre of Excellence for Cardiovascular Research, University of Toronto, The Toronto Hospital, Toronto, Ontario, CanadaCorrespondence[email protected]
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Pages 67-76 | Received 10 May 1999, Published online: 13 Jul 2016

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Luigi Mancuso, Gaetano Panzarella, Tommaso Vincenzo Bartolotta, Massimo Midiri, Disma Renda & Aurelio Maggio. (2003) Cardiac complications in thalassemia: noninvasive detection methods and new directions in the clinical management. Expert Review of Cardiovascular Therapy 1:3, pages 439-452.
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Articles from other publishers (16)

G. E. Genc, Z. Ozturk & S. Gumuslu. (2017) Selenoproteins are involved in antioxidant defense systems in thalassemia. Metallomics 9:9, pages 1241-1250.
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Wally Bartfay & Emma Bartfay. (2013) A Case–Control Study Examining the Effects of Active Versus Sedentary Lifestyles on Measures of Body Iron Burden and Oxidative Stress in Postmenopausal Women. Biological Research For Nursing 16:1, pages 38-45.
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Kelsey J. WeigelSharon G. LynchSteven M. LeVine. (2014) Iron Chelation and Multiple Sclerosis. ASN Neuro 6:1, pages AN20130037.
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Sheila A Fisher, Susan J Brunskill, Carolyn Doree, Onima Chowdhury, Sarah Gooding & David J Roberts. (2013) Oral deferiprone for iron chelation in people with thalassaemia. Cochrane Database of Systematic Reviews.
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Sheila A Fisher, Susan J Brunskill, Carolyn Doree, Sarah Gooding, Onima Chowdhury & David J Roberts. (2013) Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia. Cochrane Database of Systematic Reviews.
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Matthew E. Sweeney, Joyce G. Slusser, Sharon G. Lynch, Stephen H. Benedict, Sharon L. Garcia, Laura Rues & Steven M. LeVine. (2011) Deferiprone modulates in vitro responses by peripheral blood T cells from control and relapsing–remitting multiple sclerosis subjects. International Immunopharmacology 11:11, pages 1796-1801.
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K.M. Mitchell, A.L. Dotson, K.M. Cool, A. Chakrabarty, S.H. Benedict & S.M. LeVine. (2007) Deferiprone, an orally deliverable iron chelator, ameliorates experimental autoimmune encephalomyelitis. Multiple Sclerosis Journal 13:9, pages 1118-1126.
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David Roberts, Susan Brunskill, Carolyn Doree, Senani Williams, Jo Howard & Chris Hyde. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
David Roberts, David Rees, Jo Howard, Chris Hyde & Susan Brunskill. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Breno P. EspositoWilliam BreuerPornpan SirankaprachaPensri PootrakulChaim HershkoZ. Ioav Cabantchik. (2003) Labile plasma iron in iron overload: redox activity and susceptibility to chelation. Blood 102:7, pages 2670-2677.
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Vanessa Leung & Wally Bartfay. (2002) Investigations into the systemic production of aldehyde-derived peroxidation products in a murine model of acute iron poisoning: a dose response study. Canadian Journal of Physiology and Pharmacology 80:9, pages 851-856.
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Sarah Crowe & Wally J. Bartfay. (2016) Amlodipine Decreases Iron Uptake and Oxygen Free Radical Production in the Heart of Chronically Iron Overloaded Mice. Biological Research For Nursing 3:4, pages 189-197.
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Wally J. Bartfay & Emma Bartfay. (2016) Decreasing Effects of Iron Toxicosis on Selenium and Glutathione Peroxidase Activity. Western Journal of Nursing Research 24:2, pages 119-131.
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Wally J. Bartfay & Emma Bartfay. (2001) Selenium and Glutathione Peroxidase With Beta-Thalassemia Major. Nursing Research 50:3, pages 178-183.
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Wally J. Bartfay & Emma Bartfay. (2016) Systemic Oxygen-Free Radical Production in Iron-Loaded Mice. Western Journal of Nursing Research 22:8, pages 927-935.
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Wally J. Bartfay & Emma Bartfay. (2016) Iron-Overload Cardiomyopathy: Evidence for a Free Radical– Mediated Mechanism of Injury and Dysfunction in a Murine Model. Biological Research For Nursing 2:1, pages 49-59.
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