Advanced search
Publication Cover
Hematology Volume 22, 2017 - Issue 4
Submit an article Journal homepage
1,749
Views
57
CrossRef citations to date
0
Altmetric
Chronic Myeloid Leukemia

The role of long noncoding RNA HOTAIR in the acquired multidrug resistance to imatinib in chronic myeloid leukemia cells

Haiying WangDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China;Department of Hematology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, ChinaORCID Iconhttp://orcid.org/0000-0001-8051-1481View further author information
ORCID Icon,
Qian LiDepartment of Hematology and Blood and Marrow Transplantation, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin, China;Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, ChinaORCID Iconhttp://orcid.org/0000-0002-7698-4021View further author information
ORCID Icon,
Shusen TangDepartment of Hematology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, ChinaView further author information
,
Meifang LiDepartment of Hematology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, ChinaORCID Iconhttp://orcid.org/0000-0002-7698-4021View further author information
ORCID Icon,
Anhua FengDepartment of Hematology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, ChinaORCID Iconhttp://orcid.org/0000-0001-5850-0890View further author information
ORCID Icon,
Lili QinDepartment of Hematology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, ChinaView further author information
,
Zhiqiang LiuDepartment of Pathophysiology, Tianjin Medical University, Heping, Tianjin, ChinaCorrespondence[email protected]
View further author information
&
Xin WangDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, ChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-8051-1481View further author information
ORCID Icon show all
Pages 208-216 | Published online: 22 Nov 2016

Citations (57)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Bin Mao, Fan Wang, Jingxia Zhang, Qianqian Li & Kai Ying. (2022) Long non-coding RNA human leucocyte antigen complex group-18 HCG18 (HCG18) promoted cell proliferation and migration in head and neck squamous cell carcinoma through cyclin D1-WNT pathway. Bioengineered 13:4, pages 9425-9434.
Read now
Rubin Cheng, Yilan Huang, Yun Fang, Qirui Wang, Meixiu Yan & Yuqing Ge. (2021) Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia. Pharmaceutical Biology 59:1, pages 891-901.
Read now

Articles from other publishers (55)

Chenming Zhong, Zijun Xie & Shiwei Duan. (2023) H1Innovative approaches to combat anti‐cancer drug resistance: Targeting lncRNA and autophagy. Clinical and Translational Medicine 13:10.
Crossref
Huiping Shi, Liang Gao, Weili Zhang & Min Jiang. (2023) Long non‐coding RNAs regulate treatment outcome in leukemia: What have we learnt recently? . Cancer Medicine 12:13, pages 13966-13977.
Crossref
Mohammad H. Ghazimoradi, Naeim Karimpour-Fard & Sadegh Babashah. (2023) The Promising Role of Non-Coding RNAs as Biomarkers and Therapeutic Targets for Leukemia. Genes 14:1, pages 131.
Crossref
U Sangeetha Shenoy, Divya Adiga, Srikanth Gadicherla, Shama Prasada Kabekkodu, Keith D. Hunter & Raghu Radhakrishnan. (2023) HOX cluster-embedded lncRNAs and epithelial-mesenchymal transition in cancer: Molecular mechanisms and therapeutic opportunities. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:1, pages 188840.
Crossref
Siuli Shaw, Sartaj Khurana, Ayushi Mukherjee, Ranu Nayak & Sudeep Bose. 2023. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 1107 1123 .
XinYi QIAN, PengYuan LIU & Yan LU. (2022) The role of non-coding RNA in tumorigenesis, development,diagnosis and treatment. SCIENTIA SINICA Vitae 52:12, pages 1796-1806.
Crossref
Xiaoran Guan, Yeying Sun & Chunxiang Zhang. (2022) LncRNAs in blood cells: Roles in cell development and potential pathogenesis in hematological malignancies. Critical Reviews in Oncology/Hematology 180, pages 103849.
Crossref
Vladimir Gasic, Teodora Karan-Djurasevic, Djordje Pavlovic, Branka Zukic, Sonja Pavlovic & Natasa Tosic. (2022) Diagnostic and Therapeutic Implications of Long Non-Coding RNAs in Leukemia. Life 12:11, pages 1770.
Crossref
Alexander Rudich, Ramiro Garzon & Adrienne Dorrance. (2022) Non-Coding RNAs Are Implicit in Chronic Myeloid Leukemia Therapy Resistance. International Journal of Molecular Sciences 23:20, pages 12271.
Crossref
Le Yu, Jessica Wei & Pengda Liu. (2022) Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer. Seminars in Cancer Biology 85, pages 69-94.
Crossref
Congxue Hu, Yingqi Xu, Feng Li, Wanqi Mi, He Yu, Xinran Wang, Xin Wen, Shuaijun Chen, Xia Li, Yanjun Xu & Yunpeng Zhang. (2022) Identifying and characterizing drug sensitivity-related lncRNA-TF-gene regulatory triplets. Briefings in Bioinformatics 23:5.
Crossref
Chunming Zhu, Xia Wang, Yuan Wang & Kefeng Wang. (2022) Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistance. Cell Death Discovery 8:1.
Crossref
Wangkai Xie, Man Chu, Gendi Song, Ziyi Zuo, Zheng Han, Chenbin Chen, Yuyun Li & Zhi-wei Wang. (2022) Emerging roles of long noncoding RNAs in chemoresistance of pancreatic cancer. Seminars in Cancer Biology 83, pages 303-318.
Crossref
Swagata Roy, Neeldeep Ganguly & Satarupa Banerjee. (2022) Exploring clinical implications and role of non-coding RNAs in lung carcinogenesis. Molecular Biology Reports 49:7, pages 6871-6883.
Crossref
Jiehan Li, Shuning Guo, Zhenqiang Sun & Yang Fu. (2022) Noncoding RNAs in Drug Resistance of Gastrointestinal Stromal Tumor. Frontiers in Cell and Developmental Biology 10.
Crossref
Siuli Shaw, Sartaj Khurana, Ayushi Mukherjee, Ranu Nayak & Sudeep Bose. 2022. Handbook of Animal Models and its Uses in Cancer Research. Handbook of Animal Models and its Uses in Cancer Research 1 17 .
Rawda Ahmed Alaa Eldin, Amany Ahmed Osman, Mona Fathey Abdel Fattah Hassan, Shereen Abdel Monem Ibrahim & Yasmin Nabil El-Sakhawy. (2021) HOTAIR expression and prognostic impact in acute myeloid leukemia patients. Egyptian Journal of Medical Human Genetics 22:1.
Crossref
Saeedeh Salimi, Saman Sargazi, Milad Heidari Nia, Fariba Mirani Sargazi & Marzieh Ghasemi. (2021) Genetic variants of HOTAIR are associated with susceptibility to recurrent spontaneous abortion: A preliminary case–control study . Journal of Obstetrics and Gynaecology Research 47:11, pages 3767-3778.
Crossref
Nonthaphat Kent Wong, Shumeng Luo, Eudora Y. D. Chow, Fei Meng, Adenike Adesanya, Jiahong Sun, Herman M. H. Ma, Wenfei Jin, Wan-Chun Li, Shea Ping Yip & Chien-Ling Huang. (2021) The Tyrosine Kinase-Driven Networks of Novel Long Non-coding RNAs and Their Molecular Targets in Myeloproliferative Neoplasms. Frontiers in Cell and Developmental Biology 9.
Crossref
Haiping Song, Lijuan Chen, Wei Liu, Xiaoli Xu, Yongming Zhou, Jianhua Zhu, Xuexing Chen, Ziping Li & Hao Zhou. (2021) Depleting long noncoding RNA HOTAIR attenuates chronic myelocytic leukemia progression by binding to DNA methyltransferase 1 and inhibiting PTEN gene promoter methylation. Cell Death & Disease 12:5.
Crossref
Ning Bai, Ya Gan, Xitong Li, Shuting Gao, Wenquan Yu, Ruiyong Wang & Junbiao Chang. (2020) The role of chlorine atom on the binding between acrylonitrile derivatives and fat mass and obesity‐associated protein. Journal of Molecular Recognition 34:4.
Crossref
Rosalin Mishra, Hima Patel, Samar Alanazi, Mary Kate Kilroy & Joan T. Garrett. (2021) PI3K Inhibitors in Cancer: Clinical Implications and Adverse Effects. International Journal of Molecular Sciences 22:7, pages 3464.
Crossref
Sanhita Mitra, Somsundar Veppil Muralidharan, Mirco Di Marco, Prasanna Kumar Juvvuna, Subazini Thankaswamy Kosalai, Silke Reischl, Daniel Jachimowicz, Santhilal Subhash, Ivan Raimondi, Leo Kurian, Maite Huarte, Per Kogner, Matthias Fischer, John Inge Johnsen, Tanmoy Mondal & Chandrasekhar Kanduri. (2021) Subcellular Distribution of p53 by the p53-Responsive lncRNA NBAT1 Determines Chemotherapeutic Response in Neuroblastoma . Cancer Research 81:6, pages 1457-1471.
Crossref
Jean-Michel Carter, Daniel Aron Ang, Nicholas Sim, Andrea Budiman & Yinghui Li. (2021) Approaches to Identify and Characterise the Post-Transcriptional Roles of lncRNAs in Cancer. Non-Coding RNA 7:1, pages 19.
Crossref
Chun Yao, Fanzhi Kong, Senlin Zhang, Guihua Wang, Peng She & Qingqing Zhang. (2020) Long non‐coding RNA BANCR promotes proliferation and migration in oral squamous cell carcinoma via MAPK signaling pathway. Journal of Oral Pathology & Medicine 50:3, pages 308-315.
Crossref
Anindya Dutta, Ananya Roy & Subhrangsu Chatterjee. (2021) Long noncoding RNAs in cancer immunity: a new avenue in drug discovery. Drug Discovery Today 26:1, pages 264-272.
Crossref
Murilo S. Amaral, Lucas F. Maciel, Gilbert O. Silveira, Giovanna G. O. Olberg, João V. P. Leite, Lucas K. Imamura, Adriana S. A. Pereira, Patricia A. Miyasato, Eliana Nakano & Sergio Verjovski-Almeida. (2020) Long non-coding RNA levels can be modulated by 5-azacytidine in Schistosoma mansoni. Scientific Reports 10:1.
Crossref
Ajaz A. Bhat, Salma N. Younes, Syed Shadab Raza, Lubna Zarif, Sabah Nisar, Ikhlak Ahmed, Rashid Mir, Sachin Kumar, Surender K. Sharawat, Sheema Hashem, Imadeldin Elfaki, Michal Kulinski, Shilpa Kuttikrishnan, Kirti S. Prabhu, Abdul Q. Khan, Santosh K. Yadav, Wael El-Rifai, Mohammad A. Zargar, Hatem Zayed, Mohammad Haris & Shahab Uddin. (2020) Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance. Molecular Cancer 19:1.
Crossref
Jiahong Jiang, Shaohai Wang, Zehua Wang, Jing Cai, Lingling Han, Lisha Xie, Qing Han, Wenwen Wang, Yifan Zhang, Xiaoqi He & Chun Yang. (2020) HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer. Cancer Chemotherapy and Pharmacology 86:2, pages 295-305.
Crossref
Soudeh Ghafouri-Fard, Mohammadhosein Esmaeili & Mohammad Taheri. (2020) Expression of non-coding RNAs in hematological malignancies. European Journal of Pharmacology 875, pages 172976.
Crossref
Wenxiao Jiang, Jun Xia, Shangdan Xie, Ruanmin Zou, Shuya Pan, Zhi-wei Wang, Yehuda G. Assaraf & Xueqiong Zhu. (2020) Long non-coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs. Drug Resistance Updates 50, pages 100683.
Crossref
Ancuta Jurj, Sergiu Pasca, Patric Teodorescu, Ciprian Tomuleasa & Ioana Berindan-Neagoe. (2020) Basic knowledge on BCR-ABL1-positive extracellular vesicles. Biomarkers in Medicine 14:6, pages 451-458.
Crossref
Cristine Dieter, Eloir Dutra Lourenco & Natália Emerim Lemos. (2020) Association of long non-coding RNA and leukemia: A systematic review. Gene 735, pages 144405.
Crossref
Taruna Rajagopal, Srikanth Talluri, R.L. Akshaya & Nageswara Rao Dunna. (2020) HOTAIR LncRNA: A novel oncogenic propellant in human cancer. Clinica Chimica Acta 503, pages 1-18.
Crossref
Fei-Yan WangZhen-Yang Gu & Chun-Ji Gao. (2020) Emerging role of long non-coding RNAs in normal and malignant hematopoiesis. Chinese Medical Journal 133:4, pages 462-473.
Crossref
Yidi Qu, Hor-Yue Tan, Yau-Tuen Chan, Hongbo Jiang, Ning Wang & Di Wang. (2020) The functional role of long noncoding RNA in resistance to anticancer treatment. Therapeutic Advances in Medical Oncology 12, pages 175883592092785.
Crossref
Wen-Tao Wang, Cai Han, Yu-Meng Sun, Tian-Qi Chen & Yue-Qin Chen. (2019) Noncoding RNAs in cancer therapy resistance and targeted drug development. Journal of Hematology & Oncology 12:1.
Crossref
Jing Yang, Ji Nie, Xuelei Ma, Yuquan Wei, Yong Peng & Xiawei Wei. (2019) Targeting PI3K in cancer: mechanisms and advances in clinical trials. Molecular Cancer 18:1.
Crossref
Si-Li Wang, Yun Huang, Rui Su & Yong-Yang Yu. (2019) Silencing long non-coding RNA HOTAIR exerts anti-oncogenic effect on human acute myeloid leukemia via demethylation of HOXA5 by inhibiting Dnmt3b. Cancer Cell International 19:1.
Crossref
Morgane Gourvest, Pierre Brousset & Marina Bousquet. (2019) Long Noncoding RNAs in Acute Myeloid Leukemia: Functional Characterization and Clinical Relevance. Cancers 11:11, pages 1638.
Crossref
Chi, Wang, Wang, Yu & Yang. (2019) Long Non-Coding RNA in the Pathogenesis of Cancers. Cells 8:9, pages 1015.
Crossref
Feng Zhang, Haiwei Ni, Xiaoman Li, Hai Liu, Tao Xi & Lufeng Zheng. (2019) Lnc RNA FENDRR attenuates adriamycin resistance via suppressing MDR 1 expression through sponging HuR and miR‐184 in chronic myelogenous leukaemia cells . FEBS Letters 593:15, pages 1993-2007.
Crossref
Dimitra-Ioanna Lampropoulou, Gerasimos Aravantinos, Hector Katifelis, Foivos Lazaris, Konstantinos Laschos, Theodosios Theodosopoulos, Christos Papadimitriou & Maria Gazouli. (2019) Long non-coding RNA polymorphisms and prediction of response to chemotherapy based on irinotecan in patients with metastatic colorectal cancer. Cancer Biomarkers 25:2, pages 213-221.
Crossref
Gabriela Cruz-Miranda, Alfredo Hidalgo-Miranda, Diego Bárcenas-López, Juan Núñez-Enríquez, Julian Ramírez-Bello, Juan Mejía-Aranguré & Silvia Jiménez-Morales. (2019) Long Non-Coding RNA and Acute Leukemia. International Journal of Molecular Sciences 20:3, pages 735.
Crossref
Jingyi Yan, Didi Chen, Xiaolei Chen, Xuecheng Sun, Qiantong Dong, Changyuan Hu, Feng Zhou & Wei Chen. (2019) Downregulation of lncRNA CCDC26 contributes to imatinib resistance in human gastrointestinal stromal tumors through IGF-1R upregulation. Brazilian Journal of Medical and Biological Research 52:6.
Crossref
Jingyi Yan, Didi Chen, Xiaolei Chen, Xuecheng Sun, Qiantong Dong, Zhou Du & Tingting Wang. (2018) Identification of imatinib‑resistant long non‑coding RNAs in gastrointestinal stromal tumors. Oncology Letters.
Crossref
Nonthaphat Kent Wong, Chien-Ling Huang, Rashidul Islam & Shea Ping Yip. (2018) Long non-coding RNAs in hematological malignancies: translating basic techniques into diagnostic and therapeutic strategies. Journal of Hematology & Oncology 11:1.
Crossref
Feng Wen, Yi-Xiong Cao, Ze-Yu Luo, Pei Liao & Zhong-Wei Lu. (2018) LncRNA MALAT1 promotes cell proliferation and imatinib resistance by sponging miR-328 in chronic myelogenous leukemia. Biochemical and Biophysical Research Communications 507:1-4, pages 1-8.
Crossref
Wei Sun, Ying Shi, Zhifei Wang, Jiye Zhang, Hanhui Cai, Jungang Zhang & Dongsheng Huang. (2018) Interaction of long-chain non-coding RNAs and important signaling pathways on human cancers (Review). International Journal of Oncology.
Crossref
Fabio Corrà, Chiara Agnoletto, Linda Minotti, Federica Baldassari & Stefano Volinia. (2018) The Network of Non-coding RNAs in Cancer Drug Resistance. Frontiers in Oncology 8.
Crossref
Kha Wai Hon, Nadiah Abu, Nurul-Syakima Ab Mutalib & Rahman Jamal. (2018) miRNAs and lncRNAs as Predictive Biomarkers of Response to FOLFOX Therapy in Colorectal Cancer. Frontiers in Pharmacology 9.
Crossref
Lu HanHai-Chao ZhangLi LiCai-Xia LiXu DiXin Qu. (2018) Retracted: Downregulation of Long Noncoding RNA HOTAIR and EZH2 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Human Breast Cancer Cells . Cancer Biotherapy and Radiopharmaceuticals 33:6, pages 241-251.
Crossref
Yiping Sun, Ying Xie, Luping Du, Jingwu Sun & Zhiqiang Liu. (2018) Inhibition of BRD4 attenuates cardiomyocyte apoptosis via NF-κB pathway in a rat model of myocardial infarction. Cardiovascular Therapeutics 36:2, pages e12320.
Crossref
Akshay Malhotra, Manju Jain, Hridayesh Prakash, Karen M. Vasquez & Aklank Jain. (2017) The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer. Oncotarget 8:66, pages 110671-110684.
Crossref
A. Sayad, A. Hajifathali & M. Taheri. (2017) Polymorphisms in lncRNA HOTAIR and Susceptibility to Acute Myeloid Leukemia in Iranian Patients. Journal of Biology and Today's World 6:2.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.