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Computer Methods in Biomechanics and Biomedical Engineering Volume 16, 2013 - Issue 6
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Article

Computational fluid dynamics analysis of surgical adjustment of left ventricular assist device implantation to minimise stroke risk

Andres F. OsorioDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USA
,
Ruben OsorioDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USA
,
Andres CeballosDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USA
,
Reginald TranDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USA
,
William ClarkDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USA
,
Eduardo A. DivoDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USA;School of Engineering Technology, Daytona State College, Daytona Beach, FL, USA
,
I. Ricardo Argueta-MoralesCongenital Heart Institute at Arnold Palmer Hospital for Children, Orlando, FL, USA
,
Alain J. KassabDepartment of MechanicalMaterials and Aerospace Engineering, College of Engineering and Computer Science, University of Central Florida, Orlando, FL, USACorrespondence[email protected]
&
William M. DeCampliCongenital Heart Institute at Arnold Palmer Hospital for Children, Orlando, FL, USA;Department of SurgeryCollege of Medicine, University of Central Florida, Orlando, FL, USA
 show all
Pages 622-638 | Received 13 Jun 2011, Accepted 03 Oct 2011, Published online: 21 Dec 2011

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Ray Prather, Eduardo Divo, Alain Kassab & William DeCampli. (2022) In-silico analysis of outflow graft implantation orientation and cerebral thromboembolism incidence for full LVAD support. Computer Methods in Biomechanics and Biomedical Engineering 25:11, pages 1249-1261.
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ThuyTien Nguyen, I. Ricardo Argueta-Morales, Stephen Guimond, William Clark, Andres Ceballos, Ruben Osorio, Eduardo A. Divo, William M. De Campli & Alain J. Kassab. (2016) Computational analysis of pediatric ventricular assist device implantation to decrease cerebral particulate embolization. Computer Methods in Biomechanics and Biomedical Engineering 19:7, pages 789-799.
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Articles from other publishers (39)

Byron A. Zambrano, Shannon I. Wilson, Salma Zook, Bansi Vekaria, Michael R. Moreno & Mahwash Kassi. (2023) Computational investigation of outflow graft variation impact on hemocompatibility profile in LVADs . Artificial Organs.
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Akshita Sahni, Erin E. McIntyre, Jay D. Pal & Debanjan Mukherjee. (2023) Quantitative Assessment of Aortic Hemodynamics for Varying Left Ventricular Assist Device Outflow Graft Angles and Flow Pulsation. Annals of Biomedical Engineering 51:6, pages 1226-1243.
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Michele Girfoglio, Francesco Ballarin, Giuseppe Infantino, Francesca Nicoló, Andrea Montalto, Gianluigi Rozza, Roberto Scrofani, Marina Comisso & Francesco Musumeci. (2022) Non-intrusive PODI-ROM for patient-specific aortic blood flow in presence of a LVAD device. Medical Engineering & Physics 107, pages 103849.
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Venkat Keshav Chivukula, Gavin Loera, Dina Dragoljic, Jasmine Martinez, Jennifer A. Beckman, Song Li, Claudius Mahr & Alberto Aliseda. (2022) A Computational Hemodynamics Approach to Left Ventricular Assist Device (LVAD) Optimization Validated in a Large Patient Cohort. ASAIO Journal 68:7, pages 932-939.
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Ray Prather, Eduardo Divo, Alain Kassab & William DeCampli. (2021) Computational Fluid Dynamics Study of Cerebral Thromboembolism Risk in Ventricular Assist Device Patients: Effects of Pulsatility and Thrombus Origin. Journal of Biomechanical Engineering 143:9.
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Sung-Min Cho, Pouya Tahsili-Fahadan, Ahmet Kilic, Chun Woo Choi, Randall C. Starling & Ken Uchino. (2021) A Comprehensive Review of Risk Factor, Mechanism, and Management of Left Ventricular Assist Device–Associated Stroke. Seminars in Neurology.
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Michael McElroy, Yongcheol Kim, Giampaolo Niccoli, Rocco Vergallo, Alexander Langford-Smith, Filippo Crea, Frank Gijsen, Thomas Johnson, Amir Keshmiri & Stephen J. White. (2021) Identification of the haemodynamic environment permissive for plaque erosion. Scientific Reports 11:1.
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Michael McElroy, Antonios Xenakis & Amir Keshmiri. (2020) Impact of heart failure severity on ventricular assist device haemodynamics: a computational study. Research on Biomedical Engineering 36:4, pages 489-500.
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Omid Amili, Robroy MacIver & Filippo Coletti. (2020) Magnetic Resonance Imaging Based Flow Field and Lagrangian Particle Tracking From a Left Ventricular Assist Device. Journal of Biomechanical Engineering 142:2.
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Laurel M. M. Marsh, Michael C. Barbour, Venkat Keshav Chivukula, Fanette Chassagne, Cory M. Kelly, Samuel H. Levy, Louis J. Kim, Michael R. Levitt & Alberto Aliseda. (2019) Platelet Dynamics and Hemodynamics of Cerebral Aneurysms Treated with Flow-Diverting Stents. Annals of Biomedical Engineering 48:1, pages 490-501.
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F. Malone, E. McCarthy, P. Delassus, J. H. Buhk, J. Fiehler & L. Morris. (2019) Embolus Analog Trajectory Paths Under Physiological Flowrates Through Patient-Specific Aortic Arch Models. Journal of Biomechanical Engineering 141:10.
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Rishi Thaker, Raquel Araujo-Gutierrez, Hernan G. Marcos-Abdala, Tanushree Agrawal, Nadia Fida & Mahwash Kassi. (2019) Innovative Modeling Techniques and 3D Printing in Patients with Left Ventricular Assist Devices: A Bridge from Bench to Clinical Practice. Journal of Clinical Medicine 8:5, pages 635.
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Matteo Selmi, Wei-Che Chiu, Venkat Keshav Chivukula, Giulio Melisurgo, Jennifer Ann Beckman, Claudius Mahr, Alberto Aliseda, Emiliano Votta, Alberto Redaelli, Marvin J Slepian, Danny Bluestein, Federico Pappalardo & Filippo Consolo. (2018) Blood damage in Left Ventricular Assist Devices: Pump thrombosis or system thrombosis?. The International Journal of Artificial Organs 42:3, pages 113-124.
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Ajay Kadakkal & Samer S. Najjar. (2018) Neurologic Events in Continuous-Flow Left Ventricular Assist Devices. Cardiology Clinics 36:4, pages 531-539.
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Kellie Cao & William Tang. (2018) Application of Wireless Power Transfer in Totally Implantable Heart Pump. Application of Wireless Power Transfer in Totally Implantable Heart Pump.
Renzo Y. Loyaga-Rendon, Milena Jani, David Fermin, Jennifer K. McDermott, Diane Vancamp & Sangjin Lee. (2017) Prevention and Treatment of Thrombotic and Hemorrhagic Complications in Patients Supported by Continuous-Flow Left Ventricular Assist Devices. Current Heart Failure Reports 14:6, pages 465-477.
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Hyo Won Choi, Tong Luo, Jose A. Navia & Ghassan S. Kassab. (2017) Role of Aortic Geometry on Stroke Propensity based on Simulations of Patient-Specific Models. Scientific Reports 7:1.
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Anthony R. Prisco, Alberto Aliseda, Jennifer A. Beckman, Nahush A. Mokadam, Claudius Mahr & Guilherme J. M. Garcia. (2017) Impact of LVAD Implantation Site on Ventricular Blood Stagnation. ASAIO Journal 63:4, pages 392-400.
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Kenneth I. Aycock, Robert L. Campbell, Keefe B. Manning & Brent A. Craven. (2016) A resolved two-way coupled CFD/6-DOF approach for predicting embolus transport and the embolus-trapping efficiency of IVC filters. Biomechanics and Modeling in Mechanobiology 16:3, pages 851-869.
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Ray O. Prather, Alain Kassab, Marcus William Ni, Eduardo Divo, Ricardo Argueta-Morales & William M. DeCampli. (2017) Multi-scale pulsatile CFD modeling of thrombus transport in a patient-specific LVAD implantation. International Journal of Numerical Methods for Heat & Fluid Flow 27:5, pages 1022-1039.
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Sindhoor Bhat, Jayakala Mathew, Komrakshi R. Balakrishnan & Ramarathnam Krishna Kumar. (2017) Effect of Outflow Graft Size on Flow in the Aortic Arch and Cerebral Blood Flow in Continuous Flow Pumps: Possible Relevance to Strokes. ASAIO Journal 63:2, pages 144-149.
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Alberto Aliseda, Venkat Keshav Chivukula, Patrick Mcgah, Anthony R. Prisco, Jennifer A. Beckman, Guilherme J. M. Garcia, Nahush A. Mokadam & Claudius Mahr. (2017) LVAD Outflow Graft Angle and Thrombosis Risk. ASAIO Journal 63:1, pages 14-23.
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Stefan Klotz, Roza Meyer-Saraei, Alex Frydrychowicz, Michael Scharfschwerdt, Leon M. Putman, Stefanie Halder & Hans-Hinrich Sievers. (2016) Proposing a novel technique to exclude the left ventricle with an assist device: insights from 4-dimensional flow magnetic resonance imaging. European Journal of Cardio-Thoracic Surgery 50:3, pages 439-445.
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Yage Zhang, Bin Gao & Chang Yu. (2016) The hemodynamic effects of the LVAD outflow cannula location on the thrombi distribution in the aorta: A primary numerical study. Computer Methods and Programs in Biomedicine 133, pages 217-227.
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Qi ZhangBin GaoYu Chang. (2016) Effect of Different Rotational Directions of BJUT-II VAD on Aortic Swirling Flow Characteristics: A Primary Computational Fluid Dynamics Study. Medical Science Monitor 22, pages 2576-2588.
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Rosario Mazzitelli, Fergal Boyle, Eoin Murphy, Attilio Renzulli & Gionata Fragomeni. (2016) Numerical prediction of the effect of aortic Left Ventricular Assist Device outflow-graft anastomosis location. Biocybernetics and Biomedical Engineering 36:2, pages 327-343.
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Senol Piskin, Akif Ündar & Kerem Pekkan. (2015) Computational Modeling of Neonatal Cardiopulmonary Bypass Hemodynamics With Full Circle of Willis Anatomy. Artificial Organs 39:10, pages E164-E175.
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Andrew Callington, Quan Long, Prashant Mohite, Andre Simon & Tarun Kumar Mittal. (2015) Computational fluid dynamic study of hemodynamic effects on aortic root blood flow of systematically varied left ventricular assist device graft anastomosis design. The Journal of Thoracic and Cardiovascular Surgery 150:3, pages 696-704.
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William D. Clark, Benjamin A. Eslahpazir, I. Ricardo Argueta-Morales, Alain J. Kassab, Eduardo A. Divo & William M. DeCampli. (2015) Comparison Between Bench-Top and Computational Modelling of Cerebral Thromboembolism in Ventricular Assist Device Circulation. Cardiovascular Engineering and Technology 6:3, pages 242-255.
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Hyo Won Choi, Jose A. Navia & Ghassan S. Kassab. (2015) Thrombus deflector stent for stroke prevention: A simulation study. Journal of Biomechanics 48:10, pages 1789-1795.
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Jasmin S. Hanke, Sebastian V. Rojas, Andreas Martens & Jan D. Schmitto. (2015) Minimally invasive left ventricular assist device implantation with outflow graft anastomosis to the innominate artery. The Journal of Thoracic and Cardiovascular Surgery 149:4, pages e69-e70.
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Arvind Bhimaraj, Cesar Uribe & Erick E. Suarez. (2015) Physiological Impact of Continuous Flow on End-Organ Function: Clinical Implications in the Current ERA of Left Ventricular Assist Devices. Methodist DeBakey Cardiovascular Journal 11:1, pages 12-17.
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Shawn C. Shadden & Amirhossein Arzani. (2014) Lagrangian Postprocessing of Computational Hemodynamics. Annals of Biomedical Engineering 43:1, pages 41-58.
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Tim A.S. Kaufmann, Shaun D. Gregory, Martin R. B?sen, Geoff D. Tansley & Ulrich Steinseifer. (2014) Development of a Numerical Pump Testing Framework. Artificial Organs 38:9, pages 783-790.
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Mina Berty Farag, Christof Karmonik, Fabian Rengier, Matthias Loebe, Matthias Karck, Hendrik Von Tengg-Kobligk, Arjang Ruhparwar & Sasan Partovi. (2014) Review of Recent Results using Computational Fluid Dynamics Simulations in Patients Receiving Mechanical Assist Devices for End-Stage Heart Failure. Methodist DeBakey Cardiovascular Journal 10:3, pages 185.
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Alison L. Marsden, Yuri Bazilevs, Christopher C. Long & Marek Behr. (2014) Recent advances in computational methodology for simulation of mechanical circulatory assist devices. WIREs Systems Biology and Medicine 6:2, pages 169-188.
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Qi Zhang, Bin Gao, Kaiyun Gu, Yu Chang & Jinchao Xu. (2014) The Study on Hemodynamic Effect of Varied Support Models of BJUT-II VAD on Coronary Artery. ASAIO Journal 60:6, pages 643-651.
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Prahlad G. Menon, James F. Antaki, Akif Undar & Kerem Pekkan. (2013) Aortic Outflow Cannula Tip Design and Orientation Impacts Cerebral Perfusion During Pediatric Cardiopulmonary Bypass Procedures. Annals of Biomedical Engineering 41:12, pages 2588-2602.
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Andres Ceballos, I. Ricardo Argueta-Morales, Eduardo Divo, Ruben Osorio, Christopher A. Caldarone, Alain J. Kassab & William M. DeCampli. (2012) Computational Analysis of Hybrid Norwood Circulation With Distal Aortic Arch Obstruction and Reverse Blalock-Taussig Shunt. The Annals of Thoracic Surgery 94:5, pages 1540-1550.
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